Clinical trials: Disc Herniations
Lumbar Disc Herniations
Detection of Bacteria in Herniated Nucleus Material in Lumbar Disc Herniations by Culture and PCR
The aim is to investigate if herniated nucleus material in lumbar disc herniations is infected with bacteria, and if so, to determine their prevalence (control group), and to determine if patients with pre-existing Modic changes…
- Trial name
- NCT02385968
- Where
- Denmark
- Volunteers
- 5 people
- Sponsor
- Spine Centre of Southern Denmark
Lumbar Disc Herniation
The Efficacy of Clinical Pilates Exercises on Individuals With Lumbar Disc Herniation
The aim of the study is to determine the effects of clinical Pilates Exercises on the level of pain, functional status, flexibility, static and dynamic endurance of the truncus muscles and quality of life in patients with lumbar…
- Trial name
- NCT03198273
- Testing
- Clinical pilates exercises, physiotherapy program
- Where
- Cyprus
- Volunteers
- 88 people
- Sponsor
- Eastern Mediterranean University
Lumbar Spine Disease, Lumbar Disc Herniation
Perioperative Local Anesthesia Block in Spine Surgery
The purpose of the this study to evaluate the feasibility, safety, and efficacy of a fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon prior to lumbosacral surgery.
- Conditions
- Lumbar Spine Disease, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- NCT05094427
- Testing
- Preoperative fluoroscopically-guided dorsal ramus block placed by the operative neurosurgeon
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Columbia University
Trigger Point Pain, Myofascial
Trigger Point Incidence After Lumbar Disc Herniation Surgery
Our purpose is to determine the incidence of trigger points in patients who remain in a fixed position for a long time during lumbar disc herniation surgery.
- Trial name
- NCT04136197
- Testing
- Manual palpation for incidence determination
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Istanbul University - Cerrahpasa
Herniated Disc, Intervertebral Disc Displacement
Efficacy of Gabapentin or Amitriptyline to Reduce Postoperative Pain After Lumbar Laminectomy and Diskectomy
The hypothesis of this study is that Gabapentin or Amitriptyline has no role in preemptive analgesia to reduce postoperative pain after lumbar diskectomies.
- Trial name
- NCT01014520
- Testing
- Gabapentin , Amitriptyline
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Tabriz University
Displacement of Intervertebral Disc Without Myelopathy
Results of Mini-open Discectomy According to Sagittal Profile
In the normal healthy population, the sagittal alignment can be divided into four types based on the size of the sacral slope and lumbar lordosis.
- Trial name
- NCT05927662
- Testing
- lumbar discectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Lumbago, Lumbar Spinal Stenosis
Post Epidural Steroid Injection Follow-up
To determine the expected pain response timeline for patients receiving epidural steroid injections, our team plans to assess patient pain severity and degree of pain relief every 3 days for 23 days.
- Conditions
- Lumbago, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- NCT04207606
- Testing
- Post Epidural Steroid Injection Follow-up
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Vanderbilt University Medical Center
Low Back Pain, Low Back Pain, Mechanical
Effects of Mechanical Versus Manual Traction in the Management of Low Back Pain.
This study compared the effects of mechanical and manual traction on pain, disability and lumbar spinal curvature in patients with discogenic low back pain
- Conditions
- Low Back Pain, Low Back Pain, Mechanical, Disc Degeneration, Disc Prolapse
- Trial name
- NCT05059249
- Testing
- Hot Pack, Manual Traction, Mechanical Traction
- Where
- Pakistan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Foundation University Islamabad
Pain, Nerve, Prolapsed Intervertebral Disc
Role Of Pregabalin To Decrease Postoperative Pain In Microdiscectomy
The purpose of this study is to compare the effect of pregabalin in reducing the neuropathic pain in postoperative patients who have undergone single level Microdiscectomy for prolapsed intervetebral lumbar disc.
- Trial name
- NCT04653792
- Testing
- Pregabalin 75mg
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Ziauddin University
Lumbar Herniated Disc
The Effect of Ozone Therapy for Lumbar Herniated Disc
The purpose of this study is to assess the efficacy (vs. placebo) of ozone infiltration and its effectiveness in comparison with micro discectomy in the treatment of lumbar herniated disc with criteria for surgery.
- Trial name
- NCT00566007
- Testing
- Discectomy/ micro discectomy, Ozone therapy, Oxygen therapy
- Where
- Spain
- Volunteers
- 156 people
- Sponsor
- Kovacs Foundation
M-JOA Score
The Comparative Study of Full-Endoscopic Cervical Posterior Discectomy and Anterior Cervical Decompression and Fusion
Anterior cervical decompression and fusion is the standard procedure for operation of cervical disc herniations. Mobility-preserving Full-Endoscopic Cervical Posterior discectomy is the most common alternative in the case of soft…
- Trial name
- PPECD (NCT04175535)
- Testing
- Percutaneous Posterior Endoscopic Cervical Discectomy, Anterior cervical decompression and fusion
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hypertension, Disk Herniation
Effect of Hypertension on Hemodynamics in the Prone Position
Long-term use of antihypertensive drugs in patients diagnosed with hypertension may cause sharp fluctuations in the patient's hemodynamic values such as blood pressure during anesthesia.
- Trial name
- NCT06649487
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Lumbar Spine Disc Herniation
Do Oral Steroid Dose Packs Predict How Well Epidural Steroid Injections Will Work?
The purpose of this observational study is to show whether a standard oral steroid dose pack can be used as a screening tool to assess the effectiveness of a subsequent epidural steroid injection (ESI).
- Trial name
- NCT02026726
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Lumbar Disc Herniation
PMCFU of an Annular Closure System
The purpose of this retrospective chart review study is to collect the data that will be used to provide clinical evidence to support the post-market surveillance program.
- Trial name
- NCT05467072
- Testing
- Annular closure
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Intrinsic Therapeutics
Herniated Disc, Lower Back Pain
Chiropractic Prone Distraction for Lower Back Pain
Back pain is a major cause of disability in the United States. The lifetime prevalence of low back pain is estimated at 60-90%. Back pain has conservatively been estimated to involve total direct and indirect costs of over $25…
- Conditions
- Herniated Disc, Lower Back Pain, Sciatica
- Trial name
- NCT00269503
- Testing
- Prone Distraction, Side-Posture Manipulation, Side-Posture Manipulation & Prone Distraction
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Samueli Institute for Information Biology
Disk Herniated Lumbar
Efficacy and Safety of IntraSPINE® Associated With Discectomy in the Treatment of Lumbar Disc Herniation.
IntraSPINE® is a novel device that, unlike interspinous positioned implants, is unique in being placed more anteriorly in an interlaminar position, closer to the normal center of rotation of the motion segment.
- Trial name
- INTREUR (NCT03752671)
- Testing
- Insertion of INTRASPINE device, Discectomy
- Where
- France
- Volunteers
- 199 people
- Sponsor
- Quanta Medical
Lumbar Disc Disease, Lumbar Disc Herniation
Physiotherapy in Lumbar Disc Pathologies
The aim of this study is to compare the effectiveness of four physical therapy treatment approaches for lumbar region pathologies. Eighty volunteers who have back pain will be included in the study.
- Conditions
- Lumbar Disc Disease, Lumbar Disc Herniation, Low Back Pain, Mechanical, Low Back Strain
- Trial name
- NCT04061759
- Testing
- Effectiveness of four physical therapy approaches (soft tissue manual therapy, Kinesio® Taping techniques, stabilization exercises and reflex therapy) for treating lumbar disc pathologies.
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Guven Health Group
Lumbar Disk Herniation, Lumbar Spinal Stenosis
Screening and Prospective Cohort Study of Risk Factors for Enhanced Recovery After Spinal Fusion Surgery in Advanced Age Patient
To determine the high risk factors affecting accelerated recovery after spinal fusion surgery in advanced age patient.
- Conditions
- Lumbar Disk Herniation, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Cervical Spondylotic Myelopathy
- Trial name
- NCT06591442
- Testing
- This is an observational study
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Lumbar Disc Herniation, Pain, Postoperative
mTLIP vs. ITP Blocks in Lumbar Disc Surgery
to compare ultrasonography (USG)-guided intertransverse process block and modified thoracolumbar interfascial plan (mTLIP) block in the treatment of postoperative pain in patients undergoing lumbar disc herniation surgery under…
- Conditions
- Lumbar Disc Herniation, Pain, Postoperative, Regional Aneshesia
- Trial name
- NCT06391541
- Testing
- modified thoracolumbar interfacial plan block (mTLIP), Intertransverse process block (ITP)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Lumbar Disc Herniation, Chronic Low Back Pain
PTED Versus Radiofrequency Ablation for Lumbar Disc Herniation
Lumbar disc herniation (LDH) is a common and frequently-occurring disease giving rise to low back pain and (or) leg pain. There are about 1.5 million people with LDH-related pain, accounting for 10% of outpatients each year in…
- Trial name
- PTED (NCT03634046)
- Testing
- Percutaneous transforaminal endoscopic discectomy, Radiofrequency ablation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University