Clinical trials: Disc Herniations
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Does Teicoplanin Powder Use In Lumbar Instrumentation Surgery Reduce Surgical Site Infection
Infection after spinal surgery is one of the serious complications. Spinal surgery infection can cause high morbidity, mortality, and costs.
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Scoliosis Lumbar Region, Lumbar Spondylolisthesis
- Trial name
- NCT04341831
- Testing
- Teicoplanin
- Volunteers
- 120 people
- Sponsor
- Bezmialem Vakif University
Lomber Disc Herniation
Effectiveness of High Intensity Laser Therapy in Management of Lumbar Disc Herniation
Chronic lumbar radiculopathy is a multifactorial condition typically caused by lumbar disc herniation, where degenerative changes lead to nerve root compression, resulting in radiating pain, sensory disturbances, and motor…
- Trial name
- NCT07550569
- Testing
- Hiltherapy, physiotherapy
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Baskent University
Back Pain, Neck Pain
Treatment of Chronic Thoracic and Neck and Upper Extremity Pain
To study improvements or lack thereof with the interlaminar epidural patients with or without steroids experiences mid back, upper back or neck pain with or without chest wall and upper extremity pain of at least 6-months…
- Trial name
- NCT01071369
- Testing
- Xylocaine, Xylocaine and Celestone
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Pain Management Center of Paducah
Motor Deficits, Lumbar Discectomy
Investigation of Preoperative Factors Influencing the Outcome of Motor Deficits in Patients Undergoing Lumbar Microdiskectomy
Lumbar disc herniations may result in lower limb weakness. In such cases, there is a strong indication for surgical intervention through microdiscectomy.
- Conditions
- Motor Deficits, Lumbar Discectomy, Muscle Weakness, Paresis
- Trial name
- NCT07413302
- Where
- 3 sites in Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
VAS and JOA Scores, Adverse Reaction Rates
Combined Therapy for Cervical Disc Herniation
This study mainly explores the efficacy and safety of low-temperature plasma radiofrequency ablation combined with ozone injection and collagenase in the treatment of cervical disc herniation.The primary outcomes included the…
- Conditions
- VAS and JOA Scores, Adverse Reaction Rates, Clinical Efficacy at 1 Month and 6 Months
- Trial name
- NCT06995066
- Testing
- collagenase injection into the epidural space
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Nanchong Central Hospital
Lumbar Herniated Disc
Ozone Therapy in Patients on Waiting List for Surgery Due to Disc Herniation: Prospective, Post-authorization Study
The main objective of this study is to estimate the cost-effectiveness of ozone therapy in patients on the waiting list for surgery due to disc herniation.
- Trial name
- O3HDCIRUGIA (NCT03282695)
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Bernardino Clavo, MD, PhD
Disk Herniated Lumbar
Safety and Performance of a Hernia Blocking System
Prospective, multi-center, single-arm clinical study to assess the performance of an Hernia Blocking System in preventing clinically symptomatic recurrent lumbar disc herniation.
- Trial name
- NCT04188236
- Testing
- Hernia Blocking System
- Where
- 6 sites in Spain
- Volunteers
- 30 people
- Sponsor
- NEOS Surgery
Lumbar Stenosis, Familial
Place of Ultrasound Guidance of Surgery Site in Surgery for Lumbar Canal Stenosis and Lumbar Disc Herniations
The identification of the operative site of lumbar ductal stenosis and lumbar disc herniation is classically done by radioscopy, thus inducing irradiation of the patient.
- Trial name
- NCT04124627
- Testing
- Ultrasound guidance in addition to radiographic guidance
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Medico-Chirurgicale et Obstetrique Cote d'Opale
Lumbar Disc Herniation, Lumbar Radiculopathy
The Role of Temporal Changes in Pain Response After Transforaminal Epidural Steroid Injection on Treatment Success
Transforaminal epidural steroid injection (TFESI) is a commonly used minimally invasive procedure for the treatment of lumbar radicular pain secondary to disc herniation.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Radicular Low Back Pain, Sciatica
- Trial name
- NCT07367191
- Testing
- Transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Marmara University
Pain
Clinical Effects of Gelified Ethanol Application in Cervical Disc Hernia
The aim of the study is to evaluate the clinical effects of Discogel® Radiopaque Gelified Ethanol as therapeutic substance for nucleolysis application in the patients with cervical disc hernia who had chronic pain and weakness on…
- Trial name
- NCT02834676
- Testing
- Gelified Ethanol
- Where
- Turkey (Türkiye)
- Volunteers
- 35 people
- Sponsor
- Sakarya University
Back Pain Lower Back, Magnetic Therapy
High Intensity Focused Electromagnetic Therapy on Pain and Quality of Life in Patients With Lumbar Disc Prolapse
Determine whether high intensity focused electromagnetic therapy has a significant effect on pain and quality of life in patients with lumbar disc prolapse.
- Trial name
- NCT07278596
- Testing
- High intensity focused electromagnetic therapy (HIFEMT), Stabilization exercise program
- Volunteers
- 60 people
- Sponsor
- Middle East University
Lumbar Disc Herniation
Subjective Intraoperative Use of Epidural Steroid Administration Following Discectomy
The purpose of this study is to determine a grading system for inflammation in lumbar disc herniation and which groups, if any, benefit most from the administration of an intra-operative epidural steroid.
- Trial name
- Intra-Op (NCT04182997)
- Testing
- Dexamethasone, saline 0.9%
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Missouri-Columbia
Lumbar Disc Herniation
A Questionnaire Survey Study for Exploring Outcomes for Patients With Disc Herniation
Background: The selection of primary outcomes that reflect the real symptoms and conditions of patients is instrumental in clinical studies on the effectiveness of specific treatment modalities.
- Trial name
- NCT05752838
- Testing
- No intervention
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Jaseng Medical Foundation
Disk Herniated Lumbar
Compare Effects of Ultrasound Therapy With High Intensity Laser Therapy for Treatment of Lumbar Disc Herniation.
The aim of this study is to assess and compare the effects of ultrasound therapy and High Intensity Laser Therapy, as the treatment option in case of lumbar disc herniation.
- Trial name
- NCT05261815
- Testing
- Ultrasound Therapy, High Intensity Laser Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Giant Thoracic Herniation, Myelopathy
Management of Giant Thoracic Disc Hernias by Thoracoscopy: Experience of 52 Cases
Introduction: Giant thoracic disc herniation is a rare condition for which surgical treatment is indicated when there are signs of spinal cord injury.
- Trial name
- GHTT (NCT03295617)
- Testing
- Thoracoscopy
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Hopital Foch
Lumbar Radiculopathy, Lumbar Disc Herniation
Prediction of TEI Success in Sciatica
Rationale: Treatment with transforaminal epidural injections is part of usual care in patients suffering from lumbar radiculopathy.
- Conditions
- Lumbar Radiculopathy, Lumbar Disc Herniation, Lumbar Spinal Stenosis
- Trial name
- POTEISS (NCT04540068)
- Testing
- Transforaminal Epidural Injection
- Where
- Netherlands
- Volunteers
- 388 people
- Sponsor
- Eduard Verheijen
Lumbar Disc Herniation, Lumbar Radiculopathy
Selective Nerve Root Block Versus Sham to Reduce Surgery for Lumbar Disc Herniation
The SELDISC trial will investigate whether a selective nerve root block can reduce the need for surgery in adults with a herniated disc in the lower back.
- Conditions
- Lumbar Disc Herniation, Lumbar Radiculopathy, Lumbar Disc Herniation With Radiculopathy
- Trial name
- SELDISC (NCT07895589)
- Testing
- Selective Nerve Root Block
- Where
- 2 sites in Sweden
- Volunteers
- 262 people
- Sponsor
- Karolinska Institutet
Lumbar Disc Herniation, Respiratory Mechanics
Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery
This prospective observational study aims to evaluate the relationship between changes in respiratory mechanics and cerebral oxygenation in adult patients undergoing elective lumbar disc surgery in the prone position under…
- Conditions
- Lumbar Disc Herniation, Respiratory Mechanics, Cerebral Oxygenation
- Trial name
- NCT07862257
- Testing
- Prone Positioning
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cervical Disc Herniation
Muscular Endurance And Its Association With Neck Pain, Disability, Neck Awareness, And Kinesiophobia
The aim of this study was to investigate the relationship of muscular endurance of the trunk, upper extremities, and scapular region as well as cervical region, with pain, neck awareness, and kinesiophobia in patients with…
- Trial name
- NCT05121467
- Testing
- Pain Assessment, Assessment of Muscular Endurance, Assessment of Neck Awareness
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Lumbar Disc Herniation, Radiculopathy Lumbar
Non-pharmacological Treatment and Pharmacological Treatment for Non-acute Lumbar Disc Herniation
This study is a 2-armed parallel, multi-centered, pragmatic clinical trial that compares the comparative effectiveness of non-pharmacological treatment and pharmacological treatment for non-acute lumbar disc herniation.
- Trial name
- NCT05003726
- Testing
- non-pharmacological treatment, pharmacological treatment
- Where
- 4 sites in South Korea
- Volunteers
- 36 people
- Sponsor
- Jaseng Hospital of Korean Medicine