Clinical trials: Disc Herniations
Chronic Low-back Pain, Herniated Disc
LISA Post Market Clinical Follow-Up Study: Documentation of Clinical Outcomes After Surgery With LISA Implant
The study is a post-market surveillance study of the Lumbar Implant for Stiffness Augmentation (LISA), a medical device, which is used to treat low-back pain that accompanies degenerative lesions of grades II, III, and IV…
- Conditions
- Chronic Low-back Pain, Herniated Disc, Degenerative Disc Disease, Lumbar Canal Stenosis
- Trial name
- LISA-PMCF (NCT04631133)
- Testing
- Lumbar Implant for Stiffness Augmentation (LISA)
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 136 people
- Sponsor
- BACKBONE
Herniation, Disc
Clinical Study to Evaluate the Anti-adhesion Efficacy and Safety of MegaShield®-SP in Comparison With Guardix-SP Plus After Spine Surgery
This study is Interventional, Parallel, Double-blinded, Randomized study. Subjects aged 20 to 70 years who had a Lumbar discectomy or laminectomy, MegaShield-SP® and Guardix-SP Plus will be applied.
- Trial name
- NCT06369233
- Testing
- MegaShield®-SP, Guardix-SP Plus
- Where
- 4 sites in South Korea
- Volunteers
- 80 people
- Sponsor
- L&C Bio
Radiculopathy
Presentation of Lumbar Disc and Reduction of Symptoms
The trial aims to assess the hypothesis that presentation of the disc material to the patient following a lumbar microdiscectomy would positively influence the improvement in their leg and back symptoms.
- Trial name
- POLDAROS (NCT00440856)
- Testing
- Presentation of excised intervertebral disc fragments
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- St George's, University of London
Intervertebral Disc Displacement
Comparison of Software-assisted Implantation of Elastic Spine Pad (TM) With Respect to Postoperative Change in Neck Disability Index (NDI) With the Conventional Disc Spacer Squale (TM) After Anterior Cervical Discectomy for Cervical Disc Prolapse
This is an investigator-initiated study. The primary goal is to evaluate the efficacy of two different cervical disc devices (prosthesis vs rigid spacer) with respect to postoperative change in neck disability index.
- Trial name
- NCT02936765
- Testing
- Anterior cervical discectomy with prosthetic disc replacement / ESP., Anterior cervical discectomy with prosthetic disc replacement / Squale.
- Where
- Germany
- Volunteers
- 52 people
- Sponsor
- Technische Universität Dresden
Lumbar Disc Herniation
Plane Block vs Intravenous Patient Controlled Analgesia
Acute postoperative pain begins with surgical trauma and decreases with tissue healing. Untreatable postoperative pain is one of the most important problems due to the increase in respiratory, cardiac and thromboembolic…
- Trial name
- NCT04457986
- Testing
- Erector spina plane block (ESP), Modified thoracolumbar interfacial plane block (MTI), Intravenous patient controlled analgesia (IV-PCA)
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Diskapi Teaching and Research Hospital
Cervical Radiculopathy, Cervical Spondylosis
Effectiveness of Cervical Transforaminal Epidural Steroid Injection
Study Purpose: This study is intended to monitor outcomes for 1 year following cervical TFESI. Based on current clinic volume and enrollment rates into a current study of cervical epidural injections that is nearing completion…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
- Trial name
- NCT04544683
- Testing
- Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Utah
Herniated Disk Lumbar
Return to Work After Early Intervention for Lumbar Disc Herniation Versus Usual Care
The most common cause of low back pain with radiculopathy among the working population is a Lumbar Disc Herniation (LDH). In general, the natural history of sciatica is favourable with spontaneous remission.
- Trial name
- WILD (NCT04657354)
- Testing
- Assessment
- Sponsor
- Spine Centre of Southern Denmark
Disc, Herniated
Epiduroscopic Laser Discectomy Procedures
Epiduroscopy or spinal endoscopy is the imaging of the epidural space using a percutaneous and minimally invasive fiberoptic imaging device.
- Trial name
- NCT03319875
- Testing
- Epiduroscopic Laser Discectomy
- Volunteers
- 163 people
- Sponsor
- Sakarya University
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
Lumbar Disc Herniation
Comparison of Different Treatment Methods in Lumbal Disc Herniation Treatment
The aim of this study is to determine the effectiveness of three different treatment methods which consists spinal decompression, deep friction massage and exercise.
- Trial name
- NCT02572622
- Testing
- non -surgical spinal decompression therapy, deep friction massage,, electrotherapy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cervical Pain, Postural Balance
Balance Performance in Dual Task in Patients With Cervical Disc Herniation Related Chronic Neck Pain:a Comparative Study
Intense pain and moderate disability are seen most patients with symptomatic cervical disc herniation (CDH). Since neck motion and motor control are associated with changes in neck pain and disability, it is highly likely that…
- Trial name
- NCT05338788
- Testing
- neck pain and dual task
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Lumbar Disc Herniation
Clinical Study on the Use of Massage to Reconstruct the Function of Lumbar Stabilizer Muscles and Improve the "Muscle and Bone Imbalance" of Lumbar Disc Herniation
1. .Characterization of Stabilizing Muscle Dysfunction in LDH Patients Using advanced techniques such as high-density surface electromyography (HD-sEMG), this study will investigate the functional imbalance of lumbar stabilizing…
- Trial name
- NCT06946979
- Testing
- Spinal Manipulation, Medication
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Zhejiang Chinese Medical University
Intervertebral Disc Displacement, Disk Herniated Lumbar
Is Regression Possible in Lumbal Disc Herniation With Spinal Mobilization Applications?
Spinal mobilization methods are passive maneuvers that are made lighter and do not exceed the physiological range of motion in order to increase joint mobility.
- Conditions
- Intervertebral Disc Displacement, Disk Herniated Lumbar, Disc Herniation
- Trial name
- NCT05753579
- Testing
- Spinal Mobilization, Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Muş Alparslan University
Intervertebral Disk Degeneration, Intervertebral Disk Displacement
Evaluation of Bone Union Following Anterior Cervical Fusion Using a NovoMax™
The purpose of this study is to evaluate the efficacy and safety of NovoMax™ in Anterior Cervical Interbody Fusion - Comparison of NovoMax™ versus ChronOs®.
- Trial name
- NCT02425514
- Testing
- Cervios ChronOs, NovoMax™
- Where
- South Korea
- Volunteers
- 76 people
- Sponsor
- BioAlpha Inc.
Radiculopathy, Neck Pain
The Value of Traction in the Treatment of Cervical Radiculopathy
The purpose of this study is to determine the effectiveness of adding mechanical traction to standard physical therapy treatments for patients with neck and arm pain.
- Conditions
- Radiculopathy, Neck Pain, Spinal Diseases, Musculoskeletal Diseases
- Trial name
- NCT00979108
- Testing
- Physical therapy rehabilitation
- Where
- 2 sites in United States
- Volunteers
- 86 people
- Sponsor
- Intermountain Health Care, Inc.
Lumbar Disc Herniation
Wallis Interspinous Dynamic Stability System for Lumbar Disc Herniation: a Prospective Study
Lumbar disc herniation is usually treated by discectomy alone. Nonfusion system such as Wallis interspinous implants have also been successfully used in disc degenerative diseases.
- Trial name
- NCT01824108
- Testing
- Lumbar discectomy, Lumbar discectomy combined with Wallis interspinous dynamic stability system
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Guangdong Provincial People's Hospital
Lumbar Disc Herniation, Gait Analysis
Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
Prospective Observation Study of the Effect of Chuna Manipulation Therapy on Gait in Patients With Lumbar Disc Herniation
- Conditions
- Lumbar Disc Herniation, Gait Analysis, Manual Therapy
- Trial name
- NCT03858556
- Testing
- Chuna manipulation, Herbal medicine, Bee venom pharmacopuncture
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jaseng Medical Foundation
Herniated Disc
Conservative Versus Aggressive Discectomy for Primary Disc Herniation With Radiculopathy
Summary: This is a prospective randomize study to compare conservative and aggressive discectomy for treatment of disc herniation with radiculopathy.
- Trial name
- NCT01204008
- Testing
- conservative discectomy, aggressive discectomy
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Diskectomy, Intervertebral Disk Displacement
Cervical Spine; Movement Before and After Anterior Cervical Discectomy, With or Without a Cervical Disc Prosthesis
The purpose of this study is to find out if use of a cervical disc prosthesis in the treatment of a cervical disc herniation preserves or restores normal mobility and movement in the cervical spine.
- Trial name
- NCT00868335
- Testing
- Activ C disc prosthesis, Anterior cervical discectomy
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Maastricht University Medical Center
Postoperative Pain
Erector Spinae Plane Block For Lumbar Disc Hernia Repair
Pain management after lomber disc hernia repair surgery is a challenging issue for anesthetists. Erector Spinae plane block is a novel analgesic technique which could be used for this purpose.
- Trial name
- NCT03744689
- Testing
- Erector Spinae Plane block, Bupivacaine Hydrochloride, PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kocaeli University