Clinical trials: Discogenic Pain, open to volunteers
Lumbar Radiculopathy
Effect of Transfer of Energy Capacitive and Resistive on Chronic Discogenic Sciatica
The goal of this clinical trial is to evaluate the effect of Transfer of Energy Capacitive and Resistive (TECAR) on pain, functional disability and electrophysiological parameters in adults with chronic discogenic sciatica .
- Trial name
- NCT07841405
- Testing
- Transfer of Energy Capacitive and Resistive (TECAR) therapy, conventional physical therapy program
- Where
- Egypt
- Volunteers
- 34 people
- Sponsor
- Cairo University
Discogenic Low Back Pain
PRP Versus NP Injections for Chronic Discogenic Low Back Pain
The purpose of this randomized, single-blind comparative-effectiveness pilot study is to compare the effectiveness of two types of injections on pain and function over 6 months in patients with chronic discogenic (originating…
- Trial name
- NCT07895225
- Testing
- Platelet-Rich Plasma (PRP) Injection, Nucleus Pulposus (NP) Injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Walter Reed National Military Medical Center
Lumbar Radiculopathy, Discogenic Lumbosacral Radiculopathy
Effect of Trans-spinal Electromagnetic Neuromodulation in Treatment of Patients With Discogenic Lumbosacral Radiculopathy
Purposes of the study To investigate the effect of adding Trans-spinal Electromagnetic Neuromodulation to conventional physical therapy in patients with Discogenic Lumbosacral Radiculopathy
- Trial name
- NCT07743424
- Testing
- Trans-spinal Electromagnetic Neuromodulation, Conventional physical therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Yara Aboelazm Abd Elaziz Mohamed
Lower Back Pain Chronic, Lumbar Degenerative Disease
Comparison of Clinical Outcomes, Complications Rate and Treatment Costs of Mini-TLIF and MIDLIF in the Treatment of Discogenic Low Back Pain
Background Degenerative disc disease (DDD) is the leading cause of lower back pain and disability, which prevalence increasing with age. When conservative treatment fails, surgical methods of spinal fusion are employed.
- Conditions
- Lower Back Pain Chronic, Lumbar Degenerative Disease, Lumbar Disc Degeneration, Degenerative Disc Disease(DDD)
- Trial name
- MID-MIS (NCT07127380)
- Testing
- Midline Lumbar Interbody Fusion (MIDLIF), Minimally Invasive Transforaminal Lumbar Interbody Fusion (mini-TLIF)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Copernicus Memorial Hospital
Discogenic Low Back Pain
PerQdisc Traditional Feasibility Trial.
This is a traditional feasibility study (TFS) study to evaluate the safety and effectiveness of the PerQdisc. The study is prospective, multicenter, and open label.
- Trial name
- NCT06860867
- Testing
- PerQdisc
- Where
- 8 sites in United States
- Volunteers
- 5 people
- Sponsor
- Spinal Stabilization Technologies
Discogenic Low Back Pain
Electroacupuncture Treatment for Discogenic Low Back Pain
Low back pain (LBP) is a prevalent clinical condition characterized by pain localized between the lower edge of the 12th rib and the gluteal fold.The incidence of LBP has been escalating annually.An epidemiological survey…
- Trial name
- NCT06703671
- Testing
- electroacupuncture group
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Beijing Hospital
Lumbar Discogenic Pain (Disorder)
Ethanol Gel Versus Steroid in Refractory Lumbar Discogenic Pain
DISCOGEL® is on the market since 2007. About 20,000 kits were sold to date (October 2017). The device re-obtained its CE mark in 2017. A clinical evaluation was performed by bibliographic route in 2016.
- Trial name
- IDIS (NCT03415828)
- Testing
- Ethanol gel, Prednisolone acetate
- Where
- 5 sites in France
- Volunteers
- 230 people
- Sponsor
- Gelscom SAS
Low Back Pain, Chronic Low-back Pain
AuriculoTherapy NeuroImaging
This is a clinical study of patients who have low back pain (for at least 6 months). The goal is to understand, with brain imaging, how auriculotherapy (an acupuncture-like stimulation of the ear) may work to relieve pain.
- Conditions
- Low Back Pain, Chronic Low-back Pain, Back Pain, Low, Lumbar Disc Disease
- Trial name
- ATNI (NCT06825390)
- Testing
- Cryo-auriculotherapy, Experimental auricular stimulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Keith M Vogt
Lumbar Discogenic Pain
The Safety/Efficacy Study of Human Umbilical Cord Mesenchymal Stem Cells Therapy (19#iSCLife®-LDP) for Lumbar Discogenic Pain
This experimental use umbilical cord mesenchymal stem cells in treatment of the early stage of lumbar discogenic pain (endogenous pain of the disc) to evaluate its safety and efficacy.
- Trial name
- NCT04104412
- Testing
- human umbilical cord mesenchymal stem cell
- Where
- China
- Volunteers
- 242 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Discogenic Back Pain Patients
Radiofrequency Ablation of Rammii Communicans Versus Annuloplasty in Discogenic Back Pain
Aim of the study Comparing the safety, efficacy, pain reduction, and functional disability between Ramii communicans radiofrequency versus Annuloplasty versus combined both techniques in patients with discogenic low back pain…
- Trial name
- NCT07360444
- Testing
- radiofrequency ablation of Rammii Communicans, Annuloplasty Radiofrequency Ablation
- Volunteers
- 90 people
- Sponsor
- Esraa Fathy Radwan Abd Elzaher
Discogenic Low Back Pain, Intervertebral Disc Degeneration
RenewDisc Trial: Endoscopic Discectomy and Autologous Stem Cell Therapy for Discogenic Low Back Pain
he RenewDisc Trial is a prospective observational clinical study evaluating outcomes in patients with confirmed discogenic low back pain who undergo standard clinical care using endoscopic spine procedures.
- Conditions
- Discogenic Low Back Pain, Intervertebral Disc Degeneration, Lumbar Disc Disease, Chronic Low Back Pain
- Trial name
- RENEWDISC (NCT07338877)
- Where
- Slovakia
- Volunteers
- 120 people
- Sponsor
- EPC Education s.r.o.
Degenerative Disc Disease
Study to Determine the Safety and Tolerability of TG-C in Subjects With Back Pain Due to Degenerative Disc Disease
The goal of this study is to evaluate the safety and tolerability of TG-C in subjects with chronic discogenic lumbar back pain due to degenerative disc disease.
- Trial name
- NCT06144970
- Testing
- TG-C High Dose, TG-C Mid Dose, TG-C Low Dose
- Volunteers
- 24 people
- Sponsor
- Kolon TissueGene, Inc.
Sciatica Due to Intervertebral Disc Disorder
Effect of Sensorimotor Training on Pain and Gait Performance in Patients With Discogenic Sciatica
This study aims to investigate the effect of sensorimotor training on gait performance in patients with discogenic sciatica.
- Trial name
- NCT07805265
- Testing
- Standard physical therapy, Sensorimotor Training
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Pain, Cervical, Discogenic Pain
Evaluation of Efficacy and Safety of Intradiscal Gelified Ethanol in Refractory Cervical Discogenic Pain
The purpose of this study is to assesse safety and efficacy of the Intradiscal Gelified Ethanol for treatment in refractory cervical discogenic pain.
- Trial name
- DISCOCERV (NCT05969392)
- Testing
- Intradiscal Gelified Ethanol (Discogel)
- Where
- 2 sites in Italy
- Volunteers
- 60 people
- Sponsor
- Gelscom SAS
Cervical Disc Herniation, Intervertebral Disc Displacement
Gelified Radiopaque Ethanol (Absolute Gel) in Cervical Disc Herniation: an Observational Study in Routine Clinical Practice (GENESIS)
GENESIS is a single-centre, observational, non-interventional, no-profit, investigator-initiated study conducted at Ospedale di Vimercate, ASST Brianza (Italy).
- Conditions
- Cervical Disc Herniation, Intervertebral Disc Displacement, Neck Pain, Chronic Pain
- Trial name
- GENESIS (NCT07832929)
- Testing
- Absolute Gel (radiopaque gelified ethanol)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aurel Mengri
Degenerative Disc Disease, Disc Degeneration
Clinical Trial Evaluating the Safety and Efficacy of Nucleus Pulposus Allograft in Participants With Degenerative Disc Disease
VIA Disc NP is a non-surgical intervention intended to supplement nucleus pulposus tissue in degenerated intervertebral discs. This is a randomized, sham-controlled, multi-center, double-blind clinical trial with an open label…
- Conditions
- Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain
- Trial name
- RESTORE (NCT06778447)
- Testing
- VIA Disc NP
- Where
- 19 sites in United States
- Volunteers
- 325 people
- Sponsor
- VIVEX Biologics, Inc.
Low Back Pain
Examination of Nociscan Impact on Low Back Pain Surgical Outcomes
This study is looking into how useful NOCISCAN is. NOCISCAN is a software as a Service (SaaS) tool that uses Magnetic Resonance (MR) spectroscopy.
- Trial name
- CLARITY (NCT06661850)
- Testing
- Fusion or TDR determined by investigator.
- Where
- 10 sites in United States
- Volunteers
- 300 people
- Sponsor
- Aclarion
Disc Herniation
Discogen for Low Back Pain
This study will be a double-blinded, two-arm, prospective, randomized controlled pilot feasibility study in 40 evaluable subjects (20 in each arm) at one study site within the United States.
- Trial name
- NCT06611397
- Testing
- Discogen Low pulsed ultrasound treatment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Columbia University
Oxidative Injury, Stress Physiological
TORNADO-Omics Techniques and Neural Networks for the Development of Predictive Risk Models
The goal of this observational study is to define a personalized risk model in the super healthy and homogeneous population of Italian Air Force high-performance pilots.
- Conditions
- Oxidative Injury, Stress Physiological, Discogenic Pain, Cardiovascular Risk Factor
- Trial name
- NCT06372054
- Testing
- Biological sample collection
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico