Clinical trials: Discomfort
Chronic Low Back Pain
Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain
Noxious stimuli occurring intraoperatively and postoperatively generate central sensitization, decreasing pain thresholds and ultimately increasing analgesic requirements.
- Trial name
- NCT00899600
- Testing
- Ketamine, Normal saline
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
General Population, no Specific Condition
Spanish Validation Frustration Discomfort Scale
This is an observational study aimed at validating the Frustration Discomfort Scale (Harrington, 2005). A back-translation process was followed to obtain a translated version of the scale, which was refined after a discussion…
- Trial name
- NCT04238325
- Where
- Spain
- Volunteers
- 1,513 people, healthy volunteers welcome
- Sponsor
- Universitat Jaume I
Catheter Site Pain, Catheter Site Discomfort
Investigation of New Intermittent Catheter Swelling Media in Healthy Volunteers
Investigation of novel swelling media for CE marked intermittent urinary catheters. The study was a randomized, single blinded, cross-over investigation comparing a novel swelling media with a comparator swelling media in 22…
- Trial name
- NCT04633291
- Testing
- Novel swelling media, Comparator swelling media
- Where
- Denmark
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Coloplast A/S
Emergency, Pain
Tissue Interface Pressures in Athlete Medical Extraction
This study aims to establish clinical evidence for the use of scoop stretchers in the sports setting for spinal immobilisation and transport compared to the traditionally used long back boards through measuring tissue interface…
- Conditions
- Emergency, Pain, Medical Device Discomfort
- Trial name
- NCT02770638
- Testing
- Scoop Stretcher, Long Back Spinal board
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Joint Discomfort
Effect of JointIQ on Joint Discomfort in Healthy Subjects
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effects of astragaloside supplementation on joint discomfort in healthy adults.
- Trial name
- NCT07382622
- Testing
- Astragaloside
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Vaginal Discharge, Dyspareunia
Evaluation of a Novel Female Hygiene Device for Postcoital Discomfort
Previous research has shown that semen deposition in the vagina after intercourse leads to dripping, discomfort, and vaginal odor.
- Conditions
- Vaginal Discharge, Dyspareunia, Female Sexual Dysfunction, Vaginitis
- Trial name
- NCT04885556
- Testing
- Tampon-like device for absorption of sexual fluids
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Atlantic Health System
Postoperative Thirst
Treating Post-Operative Thirst With Flavoured Ice Lollies or Water - a Comparative Study to Improve Post-operative Discomfort
Patients are asked not to eat and drink before their operation, and the investigators know that this can make people feel thirstier when they wake up from their anaesthetic.
- Trial name
- THIRST (NCT06014216)
- Testing
- Flavoured ice lollies (popsicles), Water
- Where
- United Kingdom
- Volunteers
- 173 people, healthy volunteers welcome
- Sponsor
- Gloucestershire Hospitals NHS Foundation Trust
Pain, Breast Pain
e-Nature VR: Evaluation of the Impact of Virtual Reality During Breast Biopsy
Randomized clinical trial about the evaluation of the impact of the virtual reality intervention on the experience of pain, physical and psychological discomfort, well-being and anxiety of women during breast biopsy use of nature…
- Trial name
- e-Nature VR (NCT03877094)
- Testing
- Nature virtual reality video
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Respiratory Conditions Due to Unspecified External Agent
Anti-pollution Effects of AP Green Tea Extracts
The objective of this clinical trial is to evaluate the anti-pollution effects of AP green tea extracts in subjects with discomforts related to the respiratory system by prolonged exposure to particulate matter in air pollution
- Trial name
- NCT04340375
- Testing
- AP green tea extracts
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Amorepacific Corporation
Episiotomy, Wound Healing
Use of Lactic Acid Gel for Intravaginal Use, 7 Applicators x 5ml, Bayer to Reduce Post-episiotomy Discomfort
This prospective controlled study evaluates the efficacy of topical lactic acid gel in enhancing episiotomy wound healing and improving postpartum sexual quality of life.
- Conditions
- Episiotomy, Wound Healing, Postpartum Period
- Trial name
- LA30051990 (NCT06978049)
- Testing
- Topical Lactic Acid Gel (BAYER)
- Where
- Romania
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Andrew Hospital Constanta
Stress, Fatigue
Measuring the Effect of Therapeutic Massage on Pain and Discomfort in Cardiac Cath Lab Staff
The purpose of this study is to evaluate the effect of therapeutic massage in alleviating musculoskeletal pain and discomfort associated with wearing lead aprons in the cardiac cath lab.
- Conditions
- Stress, Fatigue, Anxiety
- Trial name
- NCT01048164
- Testing
- Massage
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms
The Impact of Image-Assisted Colonoscope on Patient Experience, Physician Workload, and Examination Quality
Colonoscopy is the cornerstone for colorectal cancer screening, diagnosis, and post-treatment surveillance. Procedural quality is influenced by patient anatomy, particularly variations in colonic configuration such as sigmoid…
- Conditions
- Colorectal Cancer Screening, Colonic Polyps/Colonoscopy/Colorectal Neoplasms, Difficult Colonoscopy, Colonoscopy-Related Discomfort
- Trial name
- LOOP-p1 (NCT07541924)
- Testing
- CT-Based Image-Assisted Colonoscope Insertion
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- DONG WU
Gastrointestinal Symptoms
Effect of Bifidobacterium Lactis HN019 on Colonic Transit Time and Digestive Symptoms
The purpose of this study was to investigate the dose response effect of Bifidobacterium lactis HN019 supplementation on colonic transit time and gastrointestinal symptoms.
- Trial name
- NCT01171014
- Testing
- Bifidobacterium lactis HN019
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fonterra Research Centre
Determination of Clinical Effects, Presence of Inflammatory Cytokines
Long Term Comparison of Ultrasonic and Hand Instrumentation in the Maintenance of Peri-implant Tissues: A Randomized Clinical Trial
Nowadays, dental implants are a very attractive and affordable treatment option for patients. According to the American Society of Implant Dentistry the dental implant market in the U.S is projected to reach $1.3 billion by…
- Conditions
- Determination of Clinical Effects, Presence of Inflammatory Cytokines, Patients Perception of Discomfort, Titanium Scalers
- Trial name
- NCT02100384
- Testing
- Peri-implant maintenance
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Application Site Discomfort, Medical Device Discomfort
Control of Tourniquet Pain With an Axillary Ring of Subcutaneous Local Anesthetic
Purpose: Even with excellent regional anesthesia of the upper extremity, tourniquet (Tq) pain from an upper arm Tq can limit the ability to use regional anesthesia as the primary anesthetic for surgical procedures on the upper…
- Trial name
- NCT01829399
- Testing
- Bupivacaine with Epinephrine, Normal Saline
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Intubation, Nasogastric
Safety and Efficacy Study of the NG Shield, a Device Intended to Reduce Pain and Discomfort Level Related to Nasogasstric Tube Usage
The purpose of the study i to demonstrate the safety and efficacy of a device that intends to reduce pain/discomfort related to nasogfastric tube usage by reducing the friction between the tube and internal orifice (nose and…
- Trial name
- NCT00781248
- Testing
- NG Shield
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nanovibronix
Local Anaesthetic Complication, Pain
Kinetic Anesthesia Device Study
Patients experience discomfort from lidocaine injections. Vibrating kinetic anesthesia devices (KAD) have been shown to reduce pain of injections in dentistry, pediatrics, and dermatology, though no studies of lidocaine…
- Trial name
- NCT03344510
- Testing
- Kinetic Anesthesia Device, Control
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Catheter Related Bladder Discomfort
Efficacy of Hyoscine-n-butylbromide in Catheter-related Bladder Discomfort After Elective Cesarean Section.
a prospective, randomized, placebo-controlled study will be conducted to investigate whether hyoscine-n-butylbromide has preventive effects on early postoperative CRBD in patients with urinary catheters who will undergo elective…
- Trial name
- NCT03513250
- Testing
- hyoscine-n-butylbromide, control group
- Where
- Egypt
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Cairo University
Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure
Effect of Limb Occlusion Pressure Attainment on Cardiovascular, Perceptual, and Performance Responses
To test the effect of limb occlusion pressure attainment in the supine, seated, and standing position on exercise performance, vascular physiology, and muscle.
- Conditions
- Blood Flow Restriction (BFR) Training Effects, Arterial Stiffness, Blood Pressure, Muscle Morphology, Perceptions
- Trial name
- NCT06718582
- Testing
- Delfi Training Device
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Teri Herberger
Unspecified Disorder of Nose and Nasal Sinuses
Immediate Effect of Proponent-Nasal-Spray on Unspecific Discomfort in the Nose
Investigation of the immediate effect on subjective relief of symptoms by Proponent - Nasal - Spray after a one time administration (following a single dose administration in each nostril) in an open, not randomised, non-blinded…
- Trial name
- NCT03251066
- Testing
- Proponent Nasal Spray
- Where
- Switzerland
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- PRECLIN Biosystems AG