Clinical trials: Disease;Neurological
Multiple Sclerosis
Disability, Perceived Social Support and Quality of Life in Multiple Sclerosis
The World Health Organization International Classification of Functioning, Disability and Health has shown that the environment can play a major role in patients' disability, and hence in their quality of life.
- Trial name
- QUALVIE-SEP (NCT02880553)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Fatigue Syndrome, Chronic, Epstein-Barr Virus Infection
Mental Training for CFS Following EBV Infection in Adolescents
The general aim of this study is to investigate the effect of an individually tailored mental training program in adolescents developing chronic fatigue syndrome (CFS) after an acute Epstein Barr-virus (EBV) infection.
- Trial name
- NCT02499302
- Testing
- Mental training
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Fibromyalgia
Efficacy and Safety of an Oral Growth Hormone Drug in the Treatment of Fibromyalgia
This is a 24-week, randomized, double-blind, placebo-controlled, trial to evaluate the safety, tolerability and efficacy of an orally administered growth hormone stimulating drug, (code named MK-0677) in the treatment of female…
- Trial name
- NCT00116129
- Testing
- Ibutamoren Mesylate (MK-0677)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Bennett, Robert, M.D.
Parkinson Disease
Treatment of Parkinson's Disease With a Transdermal Skin Patch
Patients with Parkinson's disease are missing the chemical neurotransmitter dopamine. This occurs as a result of destructive changes in an area of the brain responsible for making dopamine, the basal ganglia.
- Trial name
- NCT00001931
- Testing
- N-0923
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Delirium, Intensive Care Unit Syndrome
Delirium at the Intensive Care Unit - a Retrospective Cohort Study
This project seeks to describe the incidence of delirium in the Intensive Care Unit (ICU) and to identify risk and preventive factors associated with development of delirium.
- Trial name
- NCT02603731
- Where
- Denmark
- Volunteers
- 183 people
- Sponsor
- Zealand University Hospital
Inflammation, Sleep Deprivation
Circadian Rhythm Disruption Effects on Smoke Inhalation
Particulate matter exposure during smoke inhalation provokes inflammatory immune responses in people exposed to burning biomass including fire fighters and civilians.
- Conditions
- Inflammation, Sleep Deprivation, Circadian Rhythm Sleep Disorder, Shift Work Type, Smoke Inhalation
- Trial name
- NCT04955431
- Testing
- Sleep Restriction, Normal Sleep
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Montana
Deafness; Perception
Auditory Midbrain Implant Study
The objectives of the clinical study are to implant five deaf patients (those with Neurofibromatosis Type II, NF2) with a new two-shank auditory midbrain implant array (AMI; developed by Cochlear Limited) into the central nucleus…
- Trial name
- NCT02984202
- Testing
- auditory midbrain implant (AMI)
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- Hannover Medical School
Duchenne Muscular Dystrophy
HT-100 Long-term Study in DMD Patients Who Completed HALO-DMD-02
This study, HALO-DMD-03, is a follow-on study to HALO-DMD-01 and HALO-DMD-02, and allows continued open-label access to HT-100 for subjects who have completed these studies.
- Trial name
- NCT02525302
- Testing
- HT-100
- Where
- 5 sites in United States
- Volunteers
- 10 people
- Sponsor
- Akashi Therapeutics
Autism, Sleep Disturbances in Children
Differences in Rest, Emotion, and Arousal Modulation in Youth
The goal of this study is to examine the relationship between sensory responsivity, bedtime arousal levels, sleep disturbances, and daytime emotion dysregulation for autistic children (ages 6-10).
- Conditions
- Autism, Sleep Disturbances in Children, Sleep
- Trial name
- DREAMY-Autism (NCT07476937)
- Testing
- Power Down bedtime manipulation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Pittsburgh
Cardiovascular Diseases, Heart Failure, Congestive
Evaluating the Relationship Between Fatty Acids and Heart Disease
Cardiovascular disease (CVD) affects millions of people in the United States; each year, more people die from CVD than from any other disease.
- Conditions
- Cardiovascular Diseases, Heart Failure, Congestive, Atrial Fibrillation, Cerebrovascular Accident
- Trial name
- NCT00404872
- Where
- 4 sites in United States
- Volunteers
- 4,766 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Breast Feeding, Fatigue
Effects of Reflexology on Postpartum Pain, Fatigue, Sleep Quality and Lactation
The aim of this research is to determine the effect of foot reflexology applied to primiparous women who had cesarean section in the postpartum period on pain, fatigue, sleep quality and lactation.
- Conditions
- Breast Feeding, Fatigue, Sleep, Pain, Postoperative
- Trial name
- NCT04924439
- Testing
- foot reflexology
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Delirium, Postoperative Cognitive Dysfunction
Does APOE-e4 Predict Delirium and Cognitive Dysfunction After Surgery?
Patients with the APOE-ε4 genotype are at increased risk of both vascular dementia and peripheral vascular disease. Patients undergoing major vascular surgery are at particularly high risk of delirium and other, more subtle…
- Trial name
- NCT00911677
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- Ottawa Hospital Research Institute
Fatigue Syndrome, Chronic, Myalgic Encephalomyelitis
Oral Melatonin Plus Zinc Supplementation in Chronic Fatigue Syndrome/Myalgic Encephalomyelitis (CFS/ME)
The purpose of this study is to evaluate the effects of oral melatonin plus zinc supplementation in relieving self-reported fatigue in CFS/ME
- Trial name
- MELATOZINC (NCT03000777)
- Testing
- melatonin plus zinc
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Laboratorios Viñas, S.A.
Alzheimer Disease, Alzheimer Dementia
Multimodal Retinal Imaging in the Detection and Follow-up of Alzheimer's Disease
Because of a shared ontogenic origin, the retina displays similarities to the brain and spinal cord in terms of anatomy, functionality, response to insult, and immunology.
- Conditions
- Alzheimer Disease, Alzheimer Dementia, Mild Cognitive Impairment, Dementia
- Trial name
- RetAD (NCT03466177)
- Testing
- Non-invasive, multimodal retinal imaging
- Where
- Belgium
- Volunteers
- 320 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
End Stage Liver Disease
Pulmonary Rehabilitation in End-Stage Liver Disease
The purpose of this study is to assess the impact of exercise on sarcopenia and frailty. The exercise that will be performed in this study will include either pulmonary rehabilitation or a formal home based video strengthening…
- Trial name
- NCT03266575
- Testing
- Pulmonary Rehabilitation Exercise, Home Based Exercise
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Mayo Clinic
Sleep Apnoea, Cerebral Palsy
Ischaemic Stroke and Sleep Apnea in Northern Part of Finland
Obstructive sleep apnoea is a risk factor for ischaemic stroke. study hypothesis: In prospective study the investigators want to know how many ischaemic stroke patients have sleep apnoea and does thrombolysis play a role in…
- Trial name
- NCT01861275
- Testing
- Nasal CPAP
- Where
- Finland
- Volunteers
- 256 people
- Sponsor
- University of Oulu
Cerebral Palsy
Effects of Walking Analysis on Surgical Outcomes
The purpose of this study is to evaluate the effects of pre-operative gait analysis testing on surgical outcomes in children with cerebral palsy who have problems walking.
- Trial name
- NCT00114075
- Testing
- Surgery with gait analysis report, Surgery without gait analysis report
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- Agency for Healthcare Research and Quality (AHRQ)
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Dietary and Exercise Interventions in Reducing Side Effects in Patients With Stage I-IIIa Breast Cancer Receiving Aromatase Inhibitors
This phase I/II trial studies how well dietary and exercise interventions work in reducing side effects in patients with stage I-IIIa breast cancer taking aromatase inhibitors.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT03953157
- Testing
- Dietary Intervention, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Sarcopenia, Breast Cancer
Exercise Intervention for Breast Cancer Patients With Sarcopenia
Sarcopenia is a common yet underrecognized complication in breast cancer survivors during rehabilitation, characterized by loss of muscle mass, reduced muscle strength, and impaired physical function, which adversely affects…
- Trial name
- EX-BCSarc (NCT07732101)
- Testing
- "Exercise for Muscle Health" Program
- Where
- China
- Volunteers
- 104 people
- Sponsor
- Capital Medical University
Dyspepsia, Emergency
Symptomatic Relief of Acute Dyspeptic Pain in Emergency Department With Pantoprazole
The purpose of this study is to evaluate the immediate synergistic effect on the relief of severe acid-related dyspeptic pain by adding intravenous pantoprazole to the combination of oral antacid and antispasmodic agent (the…
- Conditions
- Dyspepsia, Emergency, Pain
- Trial name
- NCT01281501
- Testing
- Normal saline, Pantoprazole, Oral antacid
- Where
- Thailand
- Volunteers
- 87 people
- Sponsor
- Chulalongkorn University
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