Clinical trials: Disease;Neurological
Learning Disabilities, Behavioural Problem
Transforming Care Experiences of Support Workers and Managers
What research question is being addressed? What is the experience of support workers, and managers, supporting people with learning disabilities who have moved from inpatient to community settings as part of the Transforming Care…
- Trial name
- NCT06508853
- Testing
- Qualitative research (no intervention)
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- King's College London
Parkinson Disease, Autonomic Nervous System Diseases
Biomarkers of Risk of Parkinson Disease
This study (https://pdrisk.ninds.nih.gov) will determine if people who have risk factors for Parkinson disease (PD) have biomarkers (objective ways to measure a disease process) that show that the disease process is actually…
- Conditions
- Parkinson Disease, Autonomic Nervous System Diseases, Pure Autonomic Failure
- Trial name
- NCT00775853
- Testing
- 6-[18F]Fluorodopamine, 6-[18F]Fluorodopa, 13N-Ammonia
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lung Cancer, Breast Cancer
Cambridge Brain Mets Trial 1
Proof of principle phase 1b / randomised phase 2 study of afatinib penetration into cerebral metastases for patients undergoing neurosurgical resection, both with and without prior low-dose, targeted radiotherapy.
- Conditions
- Lung Cancer, Breast Cancer, Brain Cancer, Advanced Breast Cancer
- Trial name
- CamBMT1 (NCT02768337)
- Testing
- Afatinib, 2 Gy targeted radiotherapy, 4 Gy targeted radiotherapy
- Where
- 6 sites in United Kingdom
- Volunteers
- 26 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Multiple Sclerosis, Epilepsy
Psychometric Evaluation in Patients With Brain Damage During Neuroinflammation
The presence of a damage to the central and / or peripheral nervous system resulting from diseases of a different nature (such as, Multiple Sclerosis, Parkinson's disease, dementia, head trauma, stroke, epilepsy or other…
- Conditions
- Multiple Sclerosis, Epilepsy, Parkinson Disease, Dementia
- Trial name
- NCT05450237
- Testing
- Psychometric Evaluations
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Neuromed IRCCS
Pregnancy Related, Analgesia, Epidural
Dural Puncture Epidural vs Standard Epidural Analgesia in Labor
This randomized prospective study compares Dural Puncture Epidural (DPE) and Standard Epidural Analgesia in term laboring women.
- Conditions
- Pregnancy Related, Analgesia, Epidural, Labor Pain
- Trial name
- DPE-LABOR (NCT07278895)
- Testing
- Dural Puncture Epidural (DPE), Standard Epidural Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Sclerosis, Multiple, Neurocognitive Impairment, Mild
The DANCEREX Proof-of-Concept Study for Chronic Neurological Disorders
The goal of this clinical trial is to test a new digital therapeutic solution which combines a holistic, multidimensional rehabilitation program based on dance and music with an innovative motivational system (DANCEREX-DTx) in…
- Conditions
- Sclerosis, Multiple, Neurocognitive Impairment, Mild, Neurocognitive Dysfunction
- Trial name
- DANCEREX-DTx (NCT06112639)
- Testing
- DANCEREX-DTx, Multidimensional dance-based program, Educational Program
- Where
- 3 sites in Italy
- Volunteers
- 192 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Becker Muscular Dystrophy
Effects of Sodium Nitrate on Blood Flow in Becker Muscular Dystrophy
This study is intended to build on a growing body of literature showing a blood flow abnormality in patients with Becker muscular dystrophy.
- Trial name
- NCT02147639
- Testing
- Sodium Nitrate, Sodium Nitrate - double dose, Increased exercise intensity
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Cedars-Sinai Medical Center
Cluster Headache, Episodic
Eptinezumab in Participants With Episodic Cluster Headache
The purpose of this study is to evaluate the efficacy of eptinezumab in participants with episodic Cluster Headache (eCH)
- Trial name
- ALLEVIATE (NCT04688775)
- Testing
- Eptinezumab
- Where
- 120 sites in United States, Belgium and 17 more
- Volunteers
- 231 people
- Sponsor
- H. Lundbeck A/S
Parkinson Disease
The Alouette Test in Parkinson Disease
Reading disorders in Parkinson's Disease (PD) are poorly evaluated due to the lack of validated tests to screen for them. They are often attributed to hand tremors associated with the disease.
- Trial name
- REPEAT (NCT03958175)
- Testing
- Alouette test (reading test)
- Volunteers
- 38 people
- Sponsor
- Hospices Civils de Lyon
Labor Pain
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women (PART II)
Combined spinal-epidural (CSE) for labor analgesia has been used for many years and is practiced commonly at our institution, especially when the patient requests immediate pain relief.
- Trial name
- NCT06655675
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Tonsillitis
Battlefield Auricular Acupuncture During Adult Tonsillectomies and Effect of Post op Pain and Nausea
The purpose of this study is to determine if auricular acupuncture significantly reduces post-operative pain in comparison to the standard of care.
- Trial name
- BFA (NCT02571075)
- Testing
- Auricular acupuncture
- Where
- United States
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Amblyopia, Amblyopia Occlusion
Monocular Action Video Game Treatment of Amblyopia
This study evaluates the effectiveness of the monocular treatment with action video-games in comparison with the occlusion therapy alone in amblyopic patients, and the satisfaction with the different evaluated treatments.
- Conditions
- Amblyopia, Amblyopia Occlusion, Unilateral Amblyopia, Anisometropic Amblyopia
- Trial name
- NCT04313257
- Testing
- Monocular Active Occlusion, Monocular Passive Occlusion
- Where
- Spain
- Volunteers
- 28 people
- Sponsor
- Universitat Politècnica de Catalunya
Stroke, Stroke Rehabilitation
Video-based Sit-to-stand Evaluation for Stroke Patients
The purpose of this study is to develop and validate a novel video-based postural evaluation tool designed to objectively measure the quality and dynamics of the Sit-to-Stand (STS) motion in stroke patients, specifically allowing…
- Trial name
- NCT07359001
- Testing
- Observation
- Where
- South Korea
- Volunteers
- 10 people
- Sponsor
- Sahmyook University
Coronary Artery Disease, Myocardial Infarction
WENBIT - Western Norway B Vitamin Intervention Trial
PURPOSE OF STUDY Observational studies have demonstrated that elevated levels of plasma total homocysteine is a risk factor for cardiovascular disease.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Cerebrovascular Stroke
- Trial name
- WENBIT (NCT00354081)
- Testing
- folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine), folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine)
- Where
- 2 sites in Norway
- Volunteers
- 3,096 people
- Sponsor
- Haukeland University Hospital
Phantom Limb Pain
Effects of Repetitive Transcranial Magnetic Stimulation in the Treatment of Phantom Limb Pain in Landmine Victims: ANTARES
Phantom Limb Pain (PLP) is a neuropathic chronic syndrome, characterized by a painful sensation in a body part that has been amputated.
- Trial name
- ANTARES (NCT01872481)
- Testing
- rTMS
- Where
- Colombia
- Volunteers
- 54 people
- Sponsor
- Fundación Cardiovascular de Colombia
Dementia, Alzheimer's Disease
Volunteers Adding Life in Dementia: VALID
Older adults with Alzheimer's disease and other forms of dementia frequently develop challenging neuropsychiatric symptoms (NPS) as a result of their illness.
- Trial name
- VALID (NCT01715181)
- Testing
- Volunteer visits
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- Queen's University
Cerebral Venous Thrombosis
Efficacy Comparison of Warfarin Versus Rivaroxaban CVT
With regard to Cerebral Venous Thrombosis (CVT) importance as a life threatening disease, specific care is necessary, Known anti-coagulants have limitations.Vitamin K antagonists such as Warfarin, require laboratory monitoring…
- Trial name
- NCT03747081
- Testing
- Rivaroxaban, Warfarin
- Where
- Iran
- Volunteers
- 50 people
- Sponsor
- Isfahan University of Medical Sciences
Delirium
The Validity of the Thai Version of the Confusion Assessment Method
The purpose of this study is to determine the validity and reliability of the Thai version of the Confusion Assessment Method for the intensive care (CAM-ICU) in the elderly and the prevalence of delirium in elderly.
- Trial name
- NCT01267630
- Where
- 3 sites in Thailand
- Volunteers
- 70 people
- Sponsor
- Chiang Mai University
Mild Cognitive Impairment
Mild Cognitive Impairment and Multidomain Intervention Package
The state of Kerala, India has the highest proportion of older adults and the burden of lifestyle diseases causes great concern.
- Trial name
- NCT06488430
- Testing
- Multidomain intervention package for preventing cognitive decline
- Where
- India
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
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