Clinical trials: Disease;Neurological
Ischemic Heart Disease, Ischemic Stroke
Study to Compare 2 Doses of Polycap Versus Single Dose of Polycap With or Without Pottasium
This is a randomized double blind 2x2 factorial controlled trial to evaluate efficacy tolerability of low strength Polycap versus two doses of low strength Polycap in patients with stable cardiovascular disease in reducing blood…
- Conditions
- Ischemic Heart Disease, Ischemic Stroke, Peripheral Vascular Disease, Type 2 Diabetes Mellitus
- Trial name
- TIPSK (NCT01404078)
- Testing
- Single Dose Polycap, Double dose Polycap
- Volunteers
- 518 people
- Sponsor
- St. John's Research Institute
Trigeminal Neuralgia, Refractory Pain
Fluoroscopic-Guided Bipolar Versus Monopolar Pulsed Radiofrequency for Refractory Trigeminal Neuralgia
A prospective exploratory study aiming at comparing pulsed bipolar versus pulsed unipolar radiofrequency ablation in patients with medically refractory trigeminal neuralgia.
- Trial name
- NCT06779578
- Testing
- Bipolar pulsed radiofrequency, Mopolar pulsed radiofrequency
- Where
- 2 sites in Egypt
- Volunteers
- 20 people
- Sponsor
- Alexandria University
Intracranial Atherosclerosis
ICAS Screen Based on RIC
Intracranial atherosclerosis stenosis (ICAS) is a leading cause of ischemic stroke worldwide and increase the global burden of stroke, especially in the Asian population.
- Trial name
- RICAS (NCT06610578)
- Testing
- fundus imaging
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Shoulder Arthroscopy, Knee Arthroscopy
Oral Clonidine & Gabapentin: Improving Recovery and Pain Management After Outpatient With Major Orthopedic Surgery
The purpose of this research is to investigate the non-opioid (non-narcotic) pain-relieving medications clonidine and gabapentin to see if they decrease the amount of opioid pain medications needed after surgery, thereby reducing…
- Trial name
- NCT01112878
- Testing
- Sugar pill, Gabapentin, Clonidine
- Where
- United States
- Sponsor
- Cedars-Sinai Medical Center
Pain Management
Evaluate Safety of Tramadol in the Management of Postoperative Pain Following Surgery
The study evaluates the safety of IV tramadol managing post-operative pain following surgery.
- Trial name
- NCT03395808
- Testing
- Tramadol
- Where
- United States
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Avenue Therapeutics, Inc.
Stroke
Neurofeedback for Stroke Rehabilitation
Real-time neurofeedback aims to alter brain activation patterns through online feedback of ongoing brain activity using magnetic resonance imagining (MRI).
- Trial name
- NCT03775915
- Testing
- Neurofeedback
- Where
- United Kingdom
- Volunteers
- 27 people
- Sponsor
- University of Oxford
Brain and Central Nervous System Tumors
Pharmacologic Study of Methotrexate in Patients Undergoing Stereotactic Biopsy for Recurrent High-Grade Glioma
RATIONALE: Collecting fluid from a brain tumor using a small catheter may help doctors learn how much methotrexate gets into the tumor to kill the tumor cells.
- Trial name
- NCT00463008
- Testing
- methotrexate, pharmacological study
- Volunteers
- 12 people
- Sponsor
- New Approaches to Brain Tumor Therapy Consortium
Spinal Cord Injuries
Prognostic Value of Biochemical Markers in Cerebrospinal Fluid for Functional Outcome of Spinal Cord Injured Patients
The project is aimed to develop predictive indices of spinal cord injury severity through the analysis of cerebrospinal fluid of patient collected during acute injury.
- Trial name
- NCT01861808
- Testing
- Lumbar puncture
- Where
- 4 sites in Italy
- Volunteers
- 10 people
- Sponsor
- Azienda Usl di Bologna
Fatigue, Sleep Deprivation
Effect and Utilization of Protected Time Among Interns on Extended Duty-Hour Call Shifts
This study will test the feasibility and effectiveness of protected time for physicians in training during 30 hour shifts in a medical intensive care unit. The primary outcome will be fatigue.
- Conditions
- Fatigue, Sleep Deprivation, Depression
- Trial name
- NCT00983008
- Testing
- Protected time and Dedicated time
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Providence Health & Services
Alcohol Use Disorder
Alcohol Use Disorder and Cannabidiol
This is a double-blind, placebo-controlled, parallel group study designed to assess the efficacy of full spectrum CBD and broad spectrum CBD, compared to a placebo control (PC), to reduce drinking in participants with alcohol use…
- Trial name
- NCT05613608
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of Colorado, Denver
Traumatic Brain Injury
Neurofeedback-enhanced Mindfulness Meditation in Traumatic Brain Injury
Spaulding Rehabilitation Hospital is conducting a research study evaluating the effectiveness of the brain-training product, MUSE, an EEG-guided neurofeedback device designed to assist in cultivating a relaxed, attentive state of…
- Trial name
- NCT02615535
- Testing
- EEG neurofeedback-assisted meditation, Non-EEG feedback-assisted meditation
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Spaulding Rehabilitation Hospital
Restless Legs Syndrome
Blood Changes After Exercise in Restless Legs Syndrome
The goal of this clinical trial is to learn how exercise changes molecules in the blood in people with restless legs syndrome (RLS) to better understand the cause(s) of RLS.
- Trial name
- PEARLS (NCT06481176)
- Testing
- 12-Week RLS Exercise Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Alzheimer Disease
Study to Evaluate Dietary Supplementation With a Version of Anatabloc(R) in Subjects With Alzheimer's Disease
To explore whether dietary supplementation with a version of Anatabloc(R) exerts an effect on blood levels of amyloid beta (Aβ), or impacts global or functional measures of Alzheimer's Disease (AD) in subjects with mild to…
- Trial name
- ASAP (NCT01669876)
- Testing
- Anatabloc(R)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Rock Creek Pharmaceuticals, Inc.
Stroke
Evaluation of the Genu Neurexa Orthosis in Post Stroke Patients
Post stroke patients often suffer from decrease in strength, loss of balance and gait asymmetry. Accordingly, these patients are at high risk for falls and fall-related injury. The presence of spastic or retracted muscles, e.g.
- Trial name
- NCT01395576
- Testing
- Genu Neurexa orthosis
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Post-operative Delirium
Interest in Combining Intraoperative ElectroEncephaloGram (EEG) With Assessment of Frailty to Predict Postoperative Delirium in Patients Aged >75 Years Undergoing Major Non-cardiac Surgery
Post-operative delirium (POD) is known to be independently associated with pre-operative frailty, pre-operative cognitive status and per-operative ElectroEncephaloGram (EEG).
- Trial name
- NCT06510140
- Testing
- Detection of the Post-operative delirium (POD)
- Where
- France
- Volunteers
- 55 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Amyotrophic Lateral Sclerosis
Explore Neuroprotective Effect of Lipoic Acid in Amyotrophic Lateral Sclerosis
In this proposed study, the investigators will evaluate the safety and efficacy of lipoic acid in treatment of Amyotrophic lateral sclerosis (ALS).
- Trial name
- NCT04518540
- Testing
- lipoic acid group, control group
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Stroke, Hemiparesis After Stroke
The Impact of Neuronavigation in rTMS for Hemiplegic Stroke Patients.
This is a randomized, controlled trial investigating the efficacy and precision of neuronavigation -guided repetitive transcranial magnetic stimulation (rTMS) for motor recovery in patients with subacute stroke hemiparesis.
- Trial name
- NeurorTMS-HS (NCT07284017)
- Testing
- Neuronavigation-Assisted rTMS for Stroke Hemiparesis, Standard Localization rTMS for Stroke Hemiparesis
- Volunteers
- 30 people
- Sponsor
- Taichung Veterans General Hospital
Neoplasms, Neurodegenerative Diseases
Evaluation of the Organization of Continuity of Care for Home Hospice Patients by Four Parisian Health Networks
In Paris, France, home hospice care for terminally ill patients is organized by four "palliative care networks". These networks are responsible for information sharing and coordination of all health care professionals working…
- Conditions
- Neoplasms, Neurodegenerative Diseases, Terminal Illness
- Trial name
- DICODOM (NCT03336489)
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Pain Control
Gabapentin for Perioperative Pain Relief in Surgical Abortion
Gabapentin preoperative use for evaluation of benefit to reduce pain during and after surgical office-based abortion.
- Trial name
- NCT04292171
- Testing
- Gabapentin
- Where
- United States
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- University of Nevada, Las Vegas
Vertigo, Peripheral, Vestibular Disease
The Effect of Proprioseptive Vestibular Rehabilitation in Patients With Peripheral Vestibular Hypofunction
The aim of this study was to investigate the effect of proprioceptive vestibular rehabilitation on balance, functional mobility, posture, sensory profile and quality of life in patients with vertigo due to peripheral vestibular…
- Trial name
- NCT04687371
- Testing
- Proprioceptive vestibular exercise, Standard vestibular rehabilitation exercises, Controlled
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Inonu University
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