Clinical trials: Disease Management
Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain
Analgesic Efficacy and Safety of Topical VMD-3866 Gel in Management of Pain Induced by Chemotherapy (CIPN)
Peripheral neuropathy is a disorder caused by damage to the peripheral nerves. Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of certain chemotherapy drugs, such as platinum-based compounds, taxanes…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Chemotherapy-induced Neuropathic Pain, CIPN - Chemotherapy-Induced Peripheral Neuropathy, Peripheral Neuropathic Pain
- Trial name
- NCT07072468
- Testing
- VMD-3866 Gel
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- VM Therapeutics LLC
Alcohol Use Disorder, Alcohol; Liver
CM for Patients With ALD After Liver Transplant
Alcohol associated liver disease (ALD) refers to liver injury, such as cirrhosis, that is caused by alcohol use. It affects 2 million adults in the U.S.
- Conditions
- Alcohol Use Disorder, Alcohol; Liver, Post Liver Transplant, Contingency Management
- Trial name
- NCT06304467
- Testing
- Contingency Management
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Arpan A. Patel, MD
Implementation Science, Chronic Disease Self-management
Adapting and Implementing a Chronic Disease Self-Management Program for Primary Care Patients With Opioid Use Disorder and Serious Mental Illness
The purpose of this study is to evaluate a self-management education program designed to help people with opioid use disorder (OUD), serious mental illness (SMI), and other chronic health conditions better manage their health.
- Conditions
- Implementation Science, Chronic Disease Self-management, Mental Illness, Addiction
- Trial name
- NCT07865078
- Testing
- The Chronic Disease Self-Management Program (CDSMP), Treatment as Usual plus self-management information
- Volunteers
- 40 people
- Sponsor
- University of Utah
Chronic Disease, Chronic Disease Management
Taining Golden Lake Comprehensive Chronic Disease Management Initiative
This study aims to establish the first county-level, population-based prospective cohort in Taining County, Fujian Province, China. The cohort will include at least 20,000 residents aged 18 years or older.
- Conditions
- Chronic Disease, Chronic Disease Management, Hypertension, Diabetes Mellitus
- Trial name
- TAIGOLD-CDM (NCT07308314)
- Where
- China
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Diabetes, Hypercholesterolaemia
The Effect of Providing Genetic Risk Information on Lifestyle Behaviors in African Americans
Cardiovascular disease (CVD) is a major and persistent health disparity for African Americans. Linking GAINS is a randomized pilot and feasibility study designed to evaluate whether receiving genetic risk information early in a…
- Conditions
- Diabetes, Hypercholesterolaemia, Hypertension, Obesity Type 2 Diabetes Mellitus
- Trial name
- LINKING GAINS (NCT07833384)
- Testing
- Color Genomics Genetic Testing Panels
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Choroid Disease, Caregiver
Dyadic Management Intervention in Older People With Co-occurring Cognitive Impairment and Diabetes as a Supplementary Approach to Chronic Diseases Self-Management Program
The goal of this study is to evaluate the effectiveness and implementation of a dyadic management of the Chronic Disease Self-Management Program (CDSMP) for older adults with co-occurring cognitive impairment and diabetes with…
- Conditions
- Choroid Disease, Caregiver, Self-management, Diabetes
- Trial name
- NCT07496359
- Testing
- CDSMP + caregiver support, Usual Care
- Where
- Hong Kong
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Pain, Pain Management
mHealth Intervention for Pain Self Management
This is a feasibility pilot test of a single-arm intervention to evaluate the beta version of an mHealth app-based behavioral intervention prior to scaling for a randomized controlled trial (RCT).
- Conditions
- Pain, Pain Management, Symptom Monitoring, Symptom Management
- Trial name
- PsyMINT (NCT07332377)
- Testing
- Mobile Health (mHealth) Intervention
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Longitudinal Studies, Prospective Studies
Clinical Time and Temporal Dynamics Study (CLIN-TIME)
TH-CLINICAL-TIME is a prospective, longitudinal observational study evaluating how changes in clinical measurements over time may help researchers better understand patient health trajectories and clinically meaningful outcomes.
- Conditions
- Longitudinal Studies, Prospective Studies, Biomarkers, Predictive Value of Tests
- Trial name
- CLIN-TIME (NCT07812831)
- Testing
- No Study-Assigned Intervention
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Truway Health, Inc.
Interstitial Lung Disease, Fibrotic Lung Disease
Self-efficacy and Well-being of Patients With Fibrotic Interstitial Lung Disease
Patients with fibrotic insterstitial lung disease (ILD) participating in inpatient rehabilitation or in outpatient pulmonary care will be invited to participate in this observational study.
- Conditions
- Interstitial Lung Disease, Fibrotic Lung Disease, Self Efficacy, Self-management
- Trial name
- NCT06027333
- Testing
- Inpatient rehabilitation (BRZ) or regular outpatient consultations (Insel), Blended patient education and self-management programme (PESM)
- Where
- 2 sites in Switzerland
- Volunteers
- 80 people
- Sponsor
- Berner Reha Zentrum AG
Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
The purpose of this research is to see if ketamine is effective and safe in treating children and young adults with sickle cell disease experiencing sickle cell related pain.
- Conditions
- Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease, Ketamine Infusion, Pain Management
- Trial name
- NCT07369024
- Testing
- Sub-dissociative Ketamine Infusion
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Mohsen Saidinejad
HIV, Vascular Disease
Genistein for the Reduction of Adverse Cardiovascular Events (GRACE)
People living with HIV (PLHIV) live longer because of modern HIV medicines, but even with these treatments, their bodies are more inflamed.
- Conditions
- HIV, Vascular Disease, Inflammation, Pain Management
- Trial name
- GRACE (NCT07785388)
- Testing
- Genistein (Unconjugated Isoflavones 100)
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Spinal Fusion, Hyperglycemia
Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery
This study is a randomized controlled trial that will evaluate the effect of non-invasive auricular vagal nerve stimulation on inflammatory markers, glycemic control, postoperative pain, and inflammation-related clinical outcomes…
- Conditions
- Spinal Fusion, Hyperglycemia, Postoperative Pain Management, Postoperative Care
- Trial name
- TAPIS (NCT07218133)
- Testing
- Auricular vagus nerve stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Alexander T. Yahanda
PARKINSON DISEASE (Disorder), Pain
Safinamide vs Placebo for Pain in Patients With Parkinson's Disease and Motor Fluctuations
This is a Phase III, single-center, randomized, double-blind, placebo-controlled clinical trial designed to investigate the superiority of safinamide compared to a placebo in reducing Parkinson's Disease (PD)-related pain.
- Conditions
- PARKINSON DISEASE (Disorder), Pain, Pain Management, Parkinson Disease (PD)
- Trial name
- SAVE PAIN (NCT07761936)
- Testing
- Safinamide
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Universita di Verona
Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery
ESPB vs SPSIP for Postoperative Analgesia After CABG
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral…
- Conditions
- Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery, Postoperative Pain Management
- Trial name
- ESP-SPSIP-CABG (NCT07388745)
- Testing
- Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kutahya Health Sciences University
Heart Failure, Self Care
Effect and Cost Effectiveness of a Dyadic Empowerment-based Heart Failure Management Program for Self-care
Global population aging has drastically increased healthcare spending worldwide, with the greatest portion going to hospital and community health services.
- Conditions
- Heart Failure, Self Care, Empowerment, Transitional Care
- Trial name
- NCT05806606
- Testing
- Dyadic empowerment based heart failure management program, Dyadic education program
- Where
- Hong Kong
- Volunteers
- 232 people
- Sponsor
- The University of Hong Kong
Food Insecurity, Hypertension
Delivering Food Resources & Kitchen Skills (FoRKS) to Adults With Food Insecurity and Hypertension
The goal of this clinical trial is to determine the impact of a home-delivered foods and kitchen skills program on health and nutrition in adults with high blood pressure and food insecurity.
- Conditions
- Food Insecurity, Hypertension, Nutrition, Disease Management
- Trial name
- FoRKS (NCT05856591)
- Testing
- Food Resources & Kitchen Skills (FoRKS), Enhanced Usual Care (EUC)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Indiana University
Obesity and Overweight, Obese Adolescents
Mitigation of Cardiovascular Disease Risks in Children With Extreme Obesity
The goal of this clinical trial is to learn if the drug semaglutide changes markers of disease risk as it relates to weight in children ages 12-15 years old who are obese (class 2 or 3).
- Conditions
- Obesity and Overweight, Obese Adolescents, Weight Management, Weight Loss
- Trial name
- MODERN (NCT06967389)
- Testing
- Ozempic®
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- John Bauer
COPD (Chronic Obstructive Pulmonary Disease), Self-management
Self-management Digital Intervention to Promote Physical Activity in People Living With COPD
The goal of this pilot randomized controlled trial is to evaluate the feasibility, acceptability, and preliminary effects of a theory-based self-management digital intervention (Respir'air BPCO) designed to promote physical…
- Conditions
- COPD (Chronic Obstructive Pulmonary Disease), Self-management, E-health
- Trial name
- Respir'airBPCO (NCT07262229)
- Testing
- Respir'air BPCO
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Institut et Haute Ecole de la Santé la Source
Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS)
Clinical and Economic Evaluation of Point-of-care Ultrasound-guided Infiltration for Subacromial and Carpal Tunnel Syndromes in Primary Care: a Cluster-randomized Study Protocol.
The aim of this clinical trial is to determine whether point-of-care ultrasound-guided corticosteroid injection is more effective than conventional injection guided by anatomical landmarks or standard oral medication for patients…
- Conditions
- Subacromial Impingement Syndrome, Carpal Tunnel Syndrome (CTS), Pain Management
- Trial name
- Q-EPICAP (NCT07692516)
- Testing
- Standard Oral Treatment, Conventional Infiltration, Ultrasound-Guided Infiltration
- Where
- Spain
- Volunteers
- 225 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Coronary Arterial Disease (CAD), NURSİNG
Investigation of the Relationship Between Strengthening and Ikigai Levels of Individuals With Coronary Artery Disease
cardiac rehabilitation includes topics such as smoking cessation recommendations, weight management, nutritional counseling, blood pressure management, physical activity counseling, diabetes management, psychosocial management in…
- Conditions
- Coronary Arterial Disease (CAD), NURSİNG, Disease Management, LIFE SATISFACTION
- Trial name
- NCT07040033
- Testing
- There will be no intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Kutahya Health Sciences University