Clinical trials: Disease Risk Prediction
Colorectal Cancer, Lung Metastases
AI Prediction Model and Risk Stratification for Lung Metastasis in Colorectal Cancer
Background: To assist clinicians with diagnosis and optimal treatment decision-making, we attempted to develop and validate an artificial intelligence prediction model for lung metastasis (LM) in colorectal cancer (CRC) patients.
- Trial name
- NCT05816902
- Testing
- The location of the patient's treatment
- Volunteers
- 2,779 people
- Sponsor
- Peking Union Medical College
Cardiomyopathy
Quantitive LGE Mass in Prediction of SCD in NICM Patients With Severe Cardiac Dysfunction
The purpose of this study is to establish a quantitative LGE mass based scoring system (including LGE mass on cardiac magnetic resonance , clinical features, specific medical histories, et al) for risk prediction of sudden…
- Trial name
- NCT02757742
- Where
- China
- Volunteers
- 356 people
- Sponsor
- Fu Wai Hospital, Beijing, China
Severe Preeclampsia
Risk Prediction Models for Adverse Maternal and Neonatal Outcomes in Preeclampsia
This proposal describes a single centre retrospective cross-sectional study which will address the need to further develop and test statistical risk prediction models for adverse maternal and neonatal outcomes in low-resource…
- Trial name
- NCT04058405
- Testing
- Observational
- Where
- Zimbabwe
- Volunteers
- 549 people
- Sponsor
- Mpilo Central Hospital
Coronary Artery Disease
The Predictive Value of Coronary Artery Calcium Score
In this analytical prospective study 498 patients over 40 years with any cardiovascular symptoms and without pre-established coronary artery disease ( CAD) were enrolled.
- Trial name
- NCT06311071
- Testing
- calcium score, Invasive coronary angiography
- Where
- Iran
- Volunteers
- 498 people
- Sponsor
- Shiraz University of Medical Sciences
Acute Myocardial Infraction or Chest Pain, Chronic Obstructive Pulmonary Disease (COPD)
Developing Enhanced Prediction Models
In this study, patients will be prospectively enrolled for data collection to design prediction models that integrate claims data (inpatient, outpatient, and pharmacy), electronic health record data (on clinical, social, and…
- Conditions
- Acute Myocardial Infraction or Chest Pain, Chronic Obstructive Pulmonary Disease (COPD), Congestive Heart Failure (CHF), Diabetes
- Trial name
- PREDICT (NCT02983812)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pennsylvania
Chronic Disease, Risk Assessment
Adult Disease Risk Prediction Using Wearables, Hearing, and Health Data
This prospective cohort study aims to develop and validate a personalized disease risk prediction model for adults by integrating multiple sources of health data.
- Trial name
- NCT07541547
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Health Research Institutes, Taiwan
Sarcoidosis, Pulmonary
Risk Indicators of Sarcoidosis Evolution-Unified Protocol
The purpose of this study is to develop prediction models that can prognosticate patients with sarcoidosis using clinical data and blood markers that can be obtained during a clinic visit.
- Trial name
- RISE-UP (NCT05567133)
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- University of California, San Francisco
Congenital Heart Disease, Pregnancy
Accuracy of Risk Prediction Scores in Pregnant Women
Management of pregnancy and risk stratification in congenital heart disease (CHD) population might be challenging especially due to physiological haemodynamic modifications that inevitably occur during pregnancy.
- Trial name
- PREG-GUCH (NCT04221048)
- Testing
- Retrospective observational
- Where
- France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Montpellier
Renal Cell Carcinoma (RCC), Renal Cyst
The CT-based Deep Learning Model Predicts Complications in Partial Nephrectomy
The investigators combine radiomics and deep learning to analyze the lesions more thoroughly, aiming for a more accurate prediction of complications in partial nephrectomy, and compare this approach with traditional models.
- Trial name
- NCT06876584
- Where
- China
- Volunteers
- 1,474 people
- Sponsor
- Du Lingzhi
Burnout, Sleep Disturbance
Non-Invasive Sleep Monitoring for Burnout and Retention Risk in Postgraduate Nurses
Newly graduated nurses often experience high levels of psychological stress, sleep disturbance, fatigue, and burnout during the early transition into clinical practice.
- Conditions
- Burnout, Sleep Disturbance, Occupational Stress, Mental Health
- Trial name
- NCT07666633
- Testing
- Non-Invasive Sleep Monitoring
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Armed Forces General Hospital
Neuropathy, Diabetic, Small Nerve Fiber Neuropathy
Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy
Predicting early onset neuropathy in people with type 1 diabetes
- Conditions
- Neuropathy, Diabetic, Small Nerve Fiber Neuropathy, Type 1 Diabetes
- Trial name
- NeuroPredict (NCT05546138)
- Testing
- Skin biopsies with quantification of intra-epidermal nerve fibre density, Perception Threshold Tracking, Thermal perception thresholds
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Aalborg University Hospital
Wearable Devices
Wearable Sensors and Machine Learning for the Assessment of Biomechanical Risk in Lifting Tasks
Lifting loads can cause work-related musculoskeletal disorders. The National Institute for Occupational Safety and Health (NIOSH) established a methodology for assessing lifting actions by means of a quantitative method based on…
- Trial name
- NCT05777304
- Testing
- wearable device
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA
Endometrial Cancer
Different Risk Stratification Models for Prediction of Lymph Node Involvement in Endometrial Carcinoma
Endometrial cancer is the most common malignant disease of the female genital tract and the seventh most common cause of cancer death in women in Western countries.
- Trial name
- NCT04120649
- Testing
- hysterectomy
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Leukemia, Acute
Clinical Application of Novel Panels for Early Precision Diagnosis and Relapse Prediction in High-risk Leukemia
Based on the investigator's previous data on risk classification for acute leukemia,the investigators will design a set of panels to detect the gene expression and genomic variants (SNPs, mutation, insertion, deletion and fusion…
- Trial name
- NCT03297476
- Testing
- High-risk subtype detection panels
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Zhongda Hospital
Ischemic Stroke
Post-stroke Delirium in Ischemic Stroke Patients
This study is to investigate the predictors of post-stroke delirium, develop and validate a nomogram of post-stroke delirium in the ischemic stroke patients.
- Trial name
- NCT06005636
- Testing
- Test delirium state
- Where
- China
- Volunteers
- 985 people
- Sponsor
- Jinan University Guangzhou
Hypertension, Cardiovascular Risk
Evaluation of the Clinical Benefit of the Aktiia Blood Pressure Monitoring for Early Awareness of Hypertension and Prediction of Cardiovascular Risk
Because Aktiia S.A. has been the first-ever company to put in the market an Optical Blood Pressure Monitoring device, there is a need for Aktiia S.A.
- Conditions
- Hypertension, Cardiovascular Risk, Blood Pressure Check (Hypertension Screening)
- Trial name
- FORESEE2024 (NCT06670677)
- Testing
- Lifestyle survey completion, Unlimited on-demand blood pressure measurements with G2C, Continual blood pressure measurements with G1
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Aktiia SA
Acute Pancreatitis (AP), News-2
Predictive Performance of NEWS-2 and NEWS-Calcium Scores for In-Hospital Mortality in Older Patients With Acute Pancreatitis
Acute pancreatitis is an important gastrointestinal emergency that may lead to mortality, particularly in older patients. This retrospective, single-center observational prognostic validation study aims to compare the predictive…
- Conditions
- Acute Pancreatitis (AP), News-2, Prediction of In-Hospital Mortality in Older Patients With Acute Pancreatitis
- Trial name
- NEWS (NCT07640971)
- Testing
- Retrospective Calculation of NEWS-2 Score
- Where
- Turkey (Türkiye)
- Volunteers
- 350 people
- Sponsor
- Antalya Health Sciences University
Type 2 Diabetes Mellitus (T2DM)
Precision Diabetes Education Guided by Diabetes Complication Risk Assessment
This prospective, multicenter interventional study evaluated the implementation of precision diabetes education guided by individualized diabetes complication risk assessment in adults with type 2 diabetes.
- Trial name
- PDE (NCT07793305)
- Testing
- Precision Diabetes Education (PDE)
- Where
- 6 sites in Taiwan
- Volunteers
- 180 people
- Sponsor
- Taiwanese Association of Diabetes Educators
Low Back Pain, Neck Pain
Applying Artificial Intelligence in Developing Personalized and Sustainable Healthcare for Spinal Disorders
The primary objective is to use machine learning methods on large survey and health register data to identify participants with different treatment trajectories and health outcomes after surgical and/or conservative treatment for…
- Conditions
- Low Back Pain, Neck Pain, Disc Herniation, Disc Degeneration
- Trial name
- AID-Spine (NCT05745129)
- Where
- Norway
- Volunteers
- 165,000 people
- Sponsor
- Oslo Metropolitan University
Uterine Fibroid, Recurrence
Risk Factors and A Prediction Model of Recurrence of Uterine Fibroids
To research risk factors for recurrence of uterine fibroids and build a prediction model of recurrence of uterine fibroids to facilitate the early detection as well as the early intervention for patients who are prone to recur.
- Trial name
- NCT06234670
- Testing
- No intervertion
- Where
- China
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Wenwen Wang