Clinical trials: Disease Spread
Carcinoma of the Appendix, Colorectal Cancer
Thalidomide in Treating Patients Who Have Undergone Surgery and Chemotherapy for Cancer That Has Spread Throughout the Abdomen Due to Colorectal Cancer or Appendix Cancer
RATIONALE: Thalidomide may stop the growth of tumor cells by blocking blood flow to the tumor. Giving thalidomide after surgery and chemotherapy may kill any remaining tumor cells.
- Trial name
- NCT00310076
- Testing
- thalidomide, surgery
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Wake Forest University Health Sciences
Pulmonary Tuberculosis
A Phase 2 Trial to Evaluate the Efficacy and Safety of Linezolid in Tuberculosis Patients. (LIN-CL001)
The purpose of this study is to evaluate the mycobactericidal activity, safety, tolerability, and pharmacokinetics of 6 doses of linezolid: 300 mg once per day, 300 mg twice per day, 600 mg once per day, 600 mg twice per day and…
- Trial name
- NCT02279875
- Testing
- Linezolid, HRZE (isoniazid rifampicin,pyrazinamide,ethambutol)
- Where
- 2 sites in South Africa
- Volunteers
- 113 people
- Sponsor
- Global Alliance for TB Drug Development
Neoplasms,Ovarian
Urinary Human Papilloma Virus Test in the General Population in Brittany
This is a population-based, prospective, multicenter and open-label study. 12,500 female non-respondents to the uterine cervix smear from 30 to 65 years of age in the context of the organized cervical cancer screening of the…
- Trial name
- PapU-Access (NCT03598946)
- Testing
- Urinary test
- Where
- France
- Volunteers
- 1,809 people
- Sponsor
- University Hospital, Brest
Metastatic Melanoma and Other Solid Tumors
A Study to Learn How Safe BAY2666605 is, How it Affects the Body, How it Moves Into, Through and Out of the Body, the Maximum Amount That Can be Given and Its Action Against Tumors in Adult Participants With Skin Cancer That Has Spread to Other Parts of the Body and Other Types of Advanced Cancer
Researchers are looking for a better way to treat people who have advanced cancer. In this study researchers want to learn more about a new substance called BAY2666605.
- Trial name
- NCT04809805
- Testing
- BAY2666605
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Bayer
Cervical Intraepithelial Neoplasia, Hysterectomy
Longitudinal HPV Pap in CIN and VAIN
This study will construct a longitudinal risk model of VaIN according to the HPVs distribution of cervix and vaginal for those had CIN2+.
- Conditions
- Cervical Intraepithelial Neoplasia, Hysterectomy, Human Papillomavirus, Vaginal Intraepithelial Neoplasia
- Trial name
- LHPCV (NCT05931354)
- Testing
- HPV test and Pap Smear
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chang Gung Memorial Hospital
Tuberculosis, Pulmonary
Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design
This study is a multiple-arm, multiple-stage (MAMS), phase 2, open label, randomized, controlled clinical trial that will compare the efficacy and safety of four experimental four drug regimens with a standard control regimen in…
- Trial name
- NCT01785186
- Testing
- SQ109, Rifampicin, Moxifloxacin
- Where
- 7 sites in South Africa, Tanzania
- Volunteers
- 365 people
- Sponsor
- Michael Hoelscher
Breast Cancer, Metastatic Cancer
Cellular Adoptive Immunotherapy in Treating a Patient Who Has Undergone a Donor Stem Cell Transplant for Breast Cancer That Has Spread to the Lung
RATIONALE: Biological therapy, such as cellular adoptive immunotherapy, may stimulate the immune system in different ways and stop tumor cells from growing.
- Trial name
- NCT00301730
- Testing
- aldesleukin, therapeutic tumor infiltrating lymphocytes, trastuzumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- National Cancer Institute (NCI)
COVID19
COvid-19 National Survey for Assessing VIral Spread by Nonaffected CarriErs (CON-VINCE)
CON-VINCE (COvid-19 National survey for assessing VIral spread by Non-affected CarriErs) is a national, monocentric, and longitudinal study aiming to evaluate the spread dynamics of the COVID-19 disease within the Luxembourgish…
- Trial name
- CON-VINCE (NCT04379297)
- Where
- Luxembourg
- Volunteers
- 1,870 people
- Sponsor
- Luxembourg Institute of Health
Pulmonary Tuberculosis
Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With Clofazimine (C)-TMC207 (J)-PA-824 (Pa)-Pyrazinamide (Z)
The trial will evaluate the extended bactericidal activity of 14 consecutive days of oral administration of TMC207 plus PA-824 plus Pyrazinamide plus Clofazimine, TMC207 plus PA-824 plus Pyrazinamide, TMC207 plus PA-824 plus…
- Trial name
- NC-003 (NCT01691534)
- Testing
- TMC207 (J), PA-824 (PA), pyrazinamide (Z)
- Where
- 2 sites in South Africa
- Volunteers
- 105 people
- Sponsor
- Global Alliance for TB Drug Development
Arm Lymphedema, Lymphatic Spread of Breast Cancer
Axillary Reverse Mapping Using Methylene Blue Subcutaneous Injection Can Identify Arm Lymph Nodes and Vessels, Measuring Arm Size for Lymphedema, Histopathological Examination of Arm Lymph Nodes Included With Axillary Lymph Node Dissection
study patients; axillary node negative breast cancer female, 74 patients randomly allocated in two groups each 37 patients , group I , where axillary reverse mapping(ARM) +ve nodes were preserved and axillary lymph node…
- Conditions
- Arm Lymphedema, Lymphatic Spread of Breast Cancer, Early Breast Cancer
- Trial name
- NCT04137744
- Testing
- AXILLARY REVERSE MAPPING
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Zagazig University
Tuberculosis
Xpert MTB/Rif, a New Tool for the Diagnosis of Pulmonary Tuberculosis in Two Municipalities in Brazil
Diagnosis of tuberculosis (TB) is a challenge because sputum smear, the most rapid and inexpensive test, often fails to detect the disease, in around 20 to 30% of cases.
- Trial name
- NCT01363765
- Testing
- Xpert MTB/Rif, Smear microscopy
- Where
- Brazil
- Volunteers
- 34,758 people
- Sponsor
- Ataulpho de Paiva Foundation
Cervical Intraepithelial Neoplasia, Cervical Cancer (Early Detection)
Cervical Intraepithelial Neoplasia Screening Using Liquid-Based Pap Smear Among Egyptian Women
This observational study aims to screen Egyptian women aged 25-60 for cervical intraepithelial neoplasia (CIN) using liquid-based Pap smear during routine gynecological visits at Kasr Al-Aini outpatient clinics.
- Trial name
- NCT07250841
- Testing
- Liquid-Based Pap Smear (LBC)
- Where
- Egypt
- Volunteers
- 984 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Hypertension in Pregnancy, Gestational Diabetes
Reshaping Postpartum Follow-up
The aim of this study is to evaluate the impact of personalized postpartum follow-up cards on completion of postpartum health related tasks. The intervention will consist of a card given to patients at time of discharge.
- Conditions
- Hypertension in Pregnancy, Gestational Diabetes, Cervical Dysplasia
- Trial name
- NCT06054841
- Testing
- Postpartum follow up card, Control
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Medstar Health Research Institute
Colorectal Cancer, Metastatic Cancer
Gene Therapy in Treating Patients With Colon Cancer That Has Spread to the Liver
RATIONALE: Gene therapy may make the body build an immune response to kill tumor cells. PURPOSE: Phase I trial to study the safety of NV1020 in patients who have colon cancer that has spread to the liver and has not responded to…
- Trial name
- NCT00012155
- Testing
- NV1020
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Carcinoma, Non-Small-Cell Lung
A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer (NSCLC) Which Has Spread Out.
The purpose of this study is to learn about lorlatinib for the possible treatment of lung cancer which could not be controlled. This study is seeking participants who: have lung cancer that could not be controlled.
- Trial name
- NCT06678555
- Testing
- Lorlatinib
- Where
- Taiwan
- Volunteers
- 22 people
- Sponsor
- Pfizer
Covid19, SARS-CoV2 Infection
Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask
The primary aim of the proposed research is to test the role of a newly developed reusable form-fitting fabric mask in reducing the spread of COVID-19 in a community setting comprising undergraduate students living in dormitories…
- Trial name
- NCT04979858
- Testing
- Focal Mask
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Traumatic Brain Injury
Depth Electrode Cortical Reverberation Monitoring After Traumatic Brain Injury
This is a preliminary, prospective interventional feasibility study to investigate the use of cortical reverberation (CR) monitoring in patients with traumatic brain injury (TBI) requiring a clinically indicated external…
- Trial name
- NCT07842458
- Testing
- A multi-contact depth electrode
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Samuel Cramer
Lung Cancer
Thin Prep Versus Traditional Cytological Procedure for Lung Cancer
In the diagnosis of lung cancer, the cytological sample obtained during Bronchoscopy (FBS), has an increasingly important role in the characterization of malignancy.
- Trial name
- NCT02007538
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Università degli Studi di Ferrara
COVID-19, Urologic Diseases
The Utility of Enhanced Pre and Post-surgical Work-out to Prevent the Spread of COVID-19 in a Large Urology Department
Since the outbreak of COVID-19 hit Spain in March 2020, most of the elective surgeries have been canceled everywhere. As soon as the epidemiology phase of the pandemic changed and the restrictions have been eased, different…
- Conditions
- COVID-19, Urologic Diseases, Surgery--Complications, Epidemic Disease
- Trial name
- UroCovid (NCT04409899)
- Testing
- Blood tests
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Fundacio Puigvert
HIV Infection
Co-receptor Tropism Determination of HIV-1 Subtype A Spread in the Russian Federation Using V3-based Genotyping Tools
To date, all work related to the study of HIV tropism, was performed on HIV B and C subtypes. In the studied samples, HIV variants of subtype A were virtually absent.
- Trial name
- CoTrAST (NCT01823614)
- Where
- Russia
- Volunteers
- 943 people
- Sponsor
- Dmitry Kireev