Clinical trials: Disease-Free Survival
Non-small Cell Lung Cancer, Progression, Disease
Energy for Lymphocytes
CERTIM is a cohort created in July 2015 to set up a multidisciplinary follow-up of cancer patients treated with immune checkpoint inhibitors.
- Trial name
- ELY (NCT04879316)
- Testing
- Resting Energy Expenditure measurement
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Hôpital Cochin
Rectal Cancer
Prognostic Factors Affecting Recurrence and Disease-Free Survival After Surgical Resection for Cancer Rectum
Tumor recurrence after curative surgical resection for rectal cancer is a serious complication that greatly affects the overall morbidity and the outcome.
- Trial name
- NCT06096493
- Testing
- curative surgery for cancer rectum
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- South Valley University
Oral Squamous Cell Carcinoma
Concurrent Radiotherapy and/or Cisplatin With or Without Celecoxib in Patients With Primary Oral Squamous Cell Carcinoma
The research and development of novel anti-tumor agents in oral cancer is slow, the investigation of repositioning use of currently available drugs in clinical, such as a selective cyclooxygenase-2 (COX-2) inhibitor…
- Trial name
- NCT02739204
- Testing
- Celecoxib
- Where
- Taiwan
- Volunteers
- 270 people
- Sponsor
- China Medical University Hospital
Non-Hodgkin's Lymphoma
Rituximab and CVP Plus Interferon for Follicular Non Hodgkins Lymphoma (NHL)
Rituximab plus CVP and Interferon chemoimmunotherapy for newly diagnosed Follicular Lymphoma with FLIPI index >2
- Trial name
- LNH-Pro-05 (NCT00842114)
- Testing
- R+CVP+IFN
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Fundación Leucemia y Linfoma, Spain
Gastric Cancer
Extensive Peritoneal Lavage After Curative Gastrectomy for Gastric Cancer: A Randomised Controlled Trial
This study is carried out to determine the merit and reliability of extensive intraoperative peritoneal lavage as a preventive strategy Hypothesis: EPL significantly improve the overall survival of patients by reducing the risk…
- Trial name
- EPL (NCT02140034)
- Testing
- Extensive Peritoneal Lavage
- Where
- Singapore
- Volunteers
- 600 people
- Sponsor
- National University Hospital, Singapore
Prostate Cancer
A Degarelix Trial in Patients With Prostate Cancer
A phase III extension trial comparing the efficacy and safety of degarelix 3 month depot with the established therapy Zoladex 3 month implant in patients with prostate cancer.
- Trial name
- NCT01242748
- Testing
- Degarelix, Goserelin acetate
- Where
- 63 sites in United States, Belgium and 11 more
- Volunteers
- 288 people
- Sponsor
- Ferring Pharmaceuticals
Epithelial Ovarian Cancer
A Study to Examine Olaparib Maintenance Retreatment in Patients With Epithelial Ovarian Cancer.
The OReO study will be a Phase IIIb, randomised, double-blind, placebo-controlled, multicentre study to assess the efficacy and tolerability of Olaparib retreatment, versus matching placebo, in non-mucinous epithelial ovarian…
- Trial name
- OReO (NCT03106987)
- Testing
- Active Comparator: Olaparib tablets
- Where
- 82 sites in Belgium, Canada and 9 more
- Volunteers
- 220 people
- Sponsor
- AstraZeneca
Glioblastoma Multiforme
Application of FET-PET in Fusion With MRI in the Treatment of Glioblastoma Multiforme [TYR-GLIO]
Glioblastoma multiforme (GBM WHO IV) is the most common and aggressive primary brain tumor in adults, carrying a poor prognosis with a median survival of 12-16 months.
- Trial name
- TYR-GLIO (NCT06466031)
- Testing
- MRI & PET fusion, MRI+T1C
- Where
- Poland
- Volunteers
- 189 people
- Sponsor
- Copernicus Memorial Hospital
Metastatic Gastric Cancer
Modified Folinic Acid-Fluorouracil-Oxaliplatin Regimen + Capecitabine for Elderly With Metastatic Gastric Cancer
Elderly patients are generally underrepresented in the study populations of combination chemotherapy trials. In gastric cancer patients, oxaliplatin has shown a more favorable toxicity profile than cisplatin.
- Trial name
- MATURE (NCT02002195)
- Testing
- FOLFOX, Capecitabine
- Where
- 2 sites in Italy
- Volunteers
- 47 people
- Sponsor
- International Group of Endovascular Oncology
Barrett's Esophagus
APE-Study: Ablation of Barrett's Mucosa vs. Surveillance Without Ablation in Patients Cured From Barrett's Cancer Combined With Randomization of Esomeprazole vs. Placebo for Symptomatic Reflux Control After Successful Barrett's Ablation
This is a prospective, randomized, controlled, double-blinded, multi-center trial in a parallel-group design. Aim of the study is the evaluation of tumor-free survival after ablation (by APC, argon plasma coagulation) of…
- Trial name
- APE (NCT00546065)
- Testing
- esomeprazole treatment
- Where
- Germany
- Volunteers
- 68 people
- Sponsor
- HSK Wiesbaden
Gastric Cancer
CT Imaging and Clinical Features to Predict Outcomes in Patients With Gastric Cancer
The goal of this prospective observational study is to evaluate how well a previously developed prediction model can estimate outcomes in adults with gastric cancer.
- Trial name
- NCT07776067
- Testing
- No intervention (observational study)
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Breast Neoplasms
Docetaxel, Doxorubicin (A), Cyclophosphamide (C) (TAC) vs 5-Fluorouracil, A, C (5FAC) Breast Cancer Adjuvant Treatment
This is a prospective, non-blinded randomized phase III trial. Patients will be post-surgically stratified at inclusion first according to the participating institution, then according to menopausal status and will be randomly…
- Trial name
- NCT00121992
- Testing
- Docetaxel, 5-fluorouracil, Doxorubicin
- Where
- Spain
- Volunteers
- 1,060 people
- Sponsor
- Spanish Breast Cancer Research Group
Myelofibrosis
Study to Compare Busulfan-fludarabine With Thiotepa-fludarabine Regimen in Allogeneic Transplantation for Myelofibrosis
This study will be performed as a prospective multicenter phase II trial for compare busulfan-fludarabine reduced-intensity conditioning (RIC) with thiotepa-fludarabine RIC regimen prior to allogeneic transplantation of…
- Trial name
- GITMO-MF2010 (NCT01814475)
- Testing
- A: Fludarabine + Busulphan, B: Fludarabine + Thiotepa
- Where
- 21 sites in Italy
- Volunteers
- 62 people
- Sponsor
- Gruppo Italiano Trapianto di Midollo Osseo
Tumors, Primary Neoplasm
Perioperative Risk Study
The primary objective of this trial is to determine if perioperative risk stratification and risk-based, protocol-driven management leads to a reduction in the rate of death or serious complications compared to standard…
- Conditions
- Tumors, Primary Neoplasm, Secondary Neoplasm, Surgery
- Trial name
- PRS (NCT02456389)
- Testing
- Preoperative risk stratification, Postoperative risk stratification, Risk-based, escalating levels of care
- Where
- United States
- Volunteers
- 1,456 people
- Sponsor
- Fox Chase Cancer Center
Liver Cancer
Association Between Autologous Transfusion and Recurrence-free Survival in Patients With HCC After Resection
This prospective non-randomized controlled trial aims to determine whether autotransfusion of red blood cells salvaged before liver resection is associated with the recurrence-free survival in patients with hepatocellular…
- Trial name
- AT/HCC (NCT02654028)
- Testing
- Autotransfusion, Control group
- Where
- China
- Volunteers
- 618 people, healthy volunteers welcome
- Sponsor
- Guangxi Medical University
Prostate Cancer
Working Out M0 Bipolar Androgen Therapy
The WOMBAT study will test if BAT can prolong the time it takes for nmCRPC prostate cancer to become detectable in other areas of the body (metastatic disease).
- Trial name
- WOMBAT (NCT06594926)
- Testing
- Testosterone Enanthate
- Where
- 12 sites in Australia
- Volunteers
- 69 people
- Sponsor
- Australian and New Zealand Urogenital and Prostate Cancer Trials Group
Combined Hepatocellular-cholangiocarcinoma, Liver Neoplasms
Phase II Clinical Study on the Efficacy and Safety of the Combination of Cadonilimab and Capecitabine in Adjuvant Therapy for Combined Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma
Title: A Study of Cadonilimab Combined with Capecitabine After Surgery for Mixed Type Liver Cancer This is a phase II clinical trial.
- Trial name
- NCT07243951
- Testing
- Cadonilimab, Capecitabine
- Volunteers
- 75 people
- Sponsor
- Shanghai Zhongshan Hospital
Hematological Malignancies, Hematopoietic Stem Cell Transplantation
Haplo-PBSC+Cord vs Haplo-PBSC+BM for Hematological Malignancies Undergoing Allo-HSCT
The objective of this study was to explore whether the combination with umbilical cord blood (UCB) is associated with superior disease-free survival (DFS) in the setting of haploidentical donors (HID) transplantation.
- Trial name
- NCT05290545
- Testing
- PBSCs, Cord, BMSCs
- Where
- China
- Volunteers
- 314 people
- Sponsor
- Nanfang Hospital, Southern Medical University
Melanoma Stage I, Melanoma Stage III
Adjuvant Therapy of Skin Melanoma With Alpha Interferon and Naderin
The goal of this clinical trial is to learn if adding alpha interferon to standard treatment works to prevent skin melanoma from coming back after surgery.
- Conditions
- Melanoma Stage I, Melanoma Stage III, Melanoma Stage II, Skin Melanoma
- Trial name
- ATSMAIN (NCT07671495)
- Testing
- Surgical resection, Adjuvant Radiotherapy, interferon alfa
- Volunteers
- 278 people
- Sponsor
- MIPO Clinic
Acute Lymphoblastic Leukemia
Severe Toxicity Free Survival Following Childhood Acute Lymphoblastic Leukemia
The goal of this observational study is to quantify the burden of particularly severe, long-term adverse effects in childhood acute lymphoblastic leukemia (ALL) survivors.
- Trial name
- NCT05639673
- Where
- Denmark
- Volunteers
- 5,000 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet