Clinical trials: Diseases/Diagnoses
Stress Incontinence, Female
Evaluation of Transperineal US in Stress Incontinence
Stress urinary incontinence (SUI) has an observed prevalence of between 4%and 35%.Identified risk factors are aging, obesity and repeated pregnancies and deliveries.
- Trial name
- NCT03397368
- Testing
- Transperineal Ultrasound -
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Aljazeera Hospital
Postoperative Delirium
Comparison of DRS-R-98 and 3D-CAM in the Assessment of Postoperative Delirium in Elderly Patients
Postoperative delirium (POD) is a transient and usually fully reversible altered state of consciousness that develops acutely or subacutely after surgery, characterized by widespread, daily fluctuations in brain metabolism and…
- Trial name
- NCT05992818
- Testing
- comparing DRS-R-98 (The Delirium Rating Scale--Revised-98) and 3D-CAM (3-minute diagnostic assessment for CAM-Confusion Assessment Method-defined delirium) tests to assess postoperative delirium
- Where
- Turkey (Türkiye)
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Gestational Diabetes
Risk Factors and Diagnostic Performance of Predictors as a Screening Technique for Gestational Diabetes Mellitus
Background Gestational diabetes mellitus (GDM) is a condition that can have negative impacts on both mother and baby. Detecting GDM early is crucial, and fasting plasma glucose (FPG) has been suggested as a possible screening…
- Trial name
- NCT06109597
- Testing
- 75 g glucose tolerance test
- Where
- Saudi Arabia
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz Medical City
Internet Addiction Disorder
Examining of Occupational Balance, Executive Functions, and Quality of Life of Adolescents with Internet Gaming Disorder
Internet gaming disorder leads to social problems and isolation, neglect of daily responsibilities, behavioral disorders, and cognitive and physical impairments.
- Trial name
- NCT06497166
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Concussion
EEG Diagnostic for Repetitive Sub-concussive Head Impacts
The purpose of this study is to develop a diagnostic algorithm to help with the detection, diagnosis, and monitoring of sub-concussive head impacts.
- Trial name
- NCT05562544
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Multiple Sclerosis, Neurogenic Bladder
Neurogenic Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis
There is no consensus in the literature upon the neurourological diagnostic algorithm of the patients with multiple sclerosis (MS). The primary aim of the study is phenotyping the patients with MS.
- Trial name
- NCT05587101
- Testing
- Urodynamic Study (Filling cystometry and pressure-flow study), Questionnaires, Uroflowmetry
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
SCHIZOPHRENIA 1 (Disorder), Psychosocial Adaptation
The Effects of a Solution-Focused Approach on Psychosocial Adjustment and Treatment Compliance in Individuals Diagnosed With Schizophrenia
The aim of this study is to evaluate the effects of a solution-focused approach-based individual intervention on psychosocial adjustment and treatment adherence in individuals diagnosed with schizophrenia.
- Conditions
- SCHIZOPHRENIA 1 (Disorder), Psychosocial Adaptation, Treatment Adherence
- Trial name
- NCT07144592
- Testing
- solution-oriented approach program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Muş Alparslan University
Obesity
GLP-1 Response and Effect in Individuals With Obesity Causing Genetic Mutations
The obesity epidemic is attributable to dietary and behavioral trends acting on a person's genetic makeup to determine body mass and susceptibility to obesity-related diseases.
- Trial name
- NCT02082496
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
AD - Alzheimer's Disease, MCI
A Phase I Study of [18F]Flortaucipir PET Imaging in Chinese Subjects: Safety, Pharmacokinetics, Biodistribution, Radiation Dosimetry, and Preliminary Diagnostic Efficacy
This is a non randomized, open-label Phase I study in Chinese participants. The goal of this clinical trial is to evaluate the safety and tolerability of a radioactive imaging agent called [18F]Flortaucipir Injection, which is…
- Trial name
- NCT07580703
- Testing
- [18F]Flortaucipir Injection
- Where
- China
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Eli Radiopharma
Diagnoses Disease
Atypia of Undetermined Significance (AUS) / Follicular Lesion of Undetermined Significance (FLUS)
According to the guidelines for reporting thyroid fine needle aspirations known as The Bethesda System, the category of atypical cells known as AUS/ FLUS category has an estimated rate of 5 to 15% for malignancy.
- Trial name
- NCT03224754
- Testing
- Determination of risk of malignancy of these thyroid lesions
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Mississippi Medical Center
Type 2 Diabetes Mellitus
Examination of Dermatologic Effects From Subcutaneous Injections of ISIS 113715
10 healthy volunteers will be enrolled to each receive two subcutaneous injections of ISIS 113715 in the abdomen on Study Day 1. Each subject will receive their two injections within a 5-minute period.
- Trial name
- NCT00365781
- Testing
- ISIS 113715
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Ionis Pharmaceuticals, Inc.
TMD/Orofacial Pain, Fibromyalgia (FM)
Diagnostic and Prognostic Salivary Biomarkers in Chronic Muscle Pain
A large proportion of the adult population worldwide currently lives with chronic muscle pain, with more than half of those affected experiencing pain localized to the face and jaw.
- Trial name
- NCT06994156
- Where
- Sweden
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Acromegaly
Reproducibility and Utility of OGTT in Acromegaly
Prospective study of reproducibility and utility of growth hormone inhibition by oral glucose tolerance test for the diagnosis of acromegaly, in acromegalic and non-acromegalic subjects, with a randomized double-blind crossover…
- Trial name
- ACROTEST (NCT04066569)
- Testing
- Performed 2 diagnostic tests (2 OGTT tests with 75g of Glucose)
- Where
- France
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Education, Dementia
Reuptake of an E-Learning Programme in General Practice
The evaluate the use and diffusion of an E-learning programme in Diagnostic Evaluation of Dementia among General Practitioners (GPs) in Denmark. The hypothesis are: 1. The GPs do not use the guided instructions 2.
- Trial name
- NCT00392483
- Where
- Denmark
- Volunteers
- 3,632 people, healthy volunteers welcome
- Sponsor
- Research Unit Of General Practice, Copenhagen
Acute Coronary Syndromes, ST Elevation Myocardial Infarction
Smartphone AI Assistance for Prehospital ECG Interpretation
Prehospital providers interpret 12-lead electrocardiograms (ECGs) under time pressure and without immediate expert support. Missed acute coronary occlusion - occlusion myocardial infarction (OMI) - delays reperfusion, while false…
- Conditions
- Acute Coronary Syndromes, ST Elevation Myocardial Infarction, Non-ST Elevated Myocardial Infarction, Myocardial Infarction (MI)
- Trial name
- ECG-IA (NCT07810686)
- Testing
- Smartphone large language model assistance (GPT-4o, version-locked)
- Where
- Switzerland
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- École Supérieure de Soins Ambulanciers - College of Higher Education in Prehospital Care
Skeletal Dysplasia, Reverse Overjet
Assessment of Artificial Intelligence for Treatment Decision Recommendation of Adult Skeletal Class III Patients
The study titled "Reliability Of Artificial Intelligence for Treatment Decision Recommendation of Adult Skeletal Class III Patients" aims to assess the accuracy and dependability of artificial intelligence (AI) in providing…
- Trial name
- NCT06002373
- Where
- Egypt
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pre-Eclampsia, Severe, HELLP Syndrome
Promising Bimarker Prediction of Outcome of HELLP Syndrome.
HELLP syndrome is a life-threatening obstetric complication usually considered to be a variant or complication of pre-eclampsia.
- Conditions
- Pre-Eclampsia, Severe, HELLP Syndrome, Microangiopathy
- Trial name
- NCT03246542
- Testing
- shistocytes percentage
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- AYMAN ABDELKADER MOHAMED ABDELKADER
Caries,Dental
Artificial Intellegence Rivals Digital Bitewing in Detect Secondary Caries
This study uses digital bitewing radiography as a standard for diagnosing proximal secondary caries. Patients will undergo imaging with a parallel technique and fixed settings to ensure high-quality, consistent images.
- Trial name
- NCT06667986
- Testing
- artificial intelligence models (YOLO and Mask-RCNN)
- Volunteers
- 322 people, healthy volunteers welcome
- Sponsor
- Cairo University
Melanoma (Skin), Carcinoma
App Teaches Doctors to Diagnose Skin Cancer
This study aimed to examine if self-paced learning with a novel digital patient-case-based educational platform can increase primary care physicians' diagnostic accuracy of malignant and benign skin lesions on both the level of…
- Trial name
- NCT05661370
- Testing
- Dermloop Learn
- Where
- Denmark
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Herlev Hospital
Chronic Pancreatitis
The Diagnosis of Chronic Pancreatitis
To develop a new standardized multimodal diagnostic approach to CP considering: WP 1: Fat in faeces and functional testing; the combination of tests has to be easy to practice, should take as little time as possible and…
- Trial name
- NCT01059669
- Testing
- diagnostic test
- Where
- Norway
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
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