Clinical trials: Diseases of the Genitourinary System
Prostate Cancer
Study On Lidocaine Vs. Placebo Pain Control During Transrectal Ultrasound Guided Prostate Biopsy
Patients at risk for having prostate cancer usually undergo a biopsy of their prostate. This is most often done in the private urology office.
- Trial name
- NCT00441532
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Corewell Health East
Acute Kidney Injury, Fluid Overload
Use of Biomarkers to Optimize Fluid Dosing,CRRT Initiation and Discontinuation in Pediatric ICU Patients With AKI
Acute Kidney Injury (AKI) is a common clinical problem defined by an abrupt (< 48 hour) increase in serum creatinine (SCr) resulting from an injury or insult that causes a functional or structural change in the kidney.
- Trial name
- NCT01416298
- Testing
- Continuous Renal Replacement Therapy
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Erectile Dysfunction
Clinical Investigation Using MED3000 Gel or Tadalafil Tablets in the Treatment of Erectile Dysfunction
An open-label investigation using MED3000 gel or tadalafil (5 mg) tablets in the treatment of erectile dysfunction in patients from 22 to 70 years of age. Each patients will be expected to participate for up to 30 weeks.
- Trial name
- NCT04984993
- Testing
- MED3000 (Male), Tadalafil 5mg (Male), MED3000 (Female)
- Where
- 18 sites in United States, Bulgaria and 2 more
- Volunteers
- 116 people
- Sponsor
- Futura Medical Developments Ltd.
Stress Urinary Incontinence (SUI)
Long-term Outcomes of Urethral Ligament Plication and Transvaginal Tape Surgery
In the treatment of urinary incontinence caused by coughing, sneezing, or heavy lifting, the investigators will perform urinary tract tightening surgery, both with and without a sling, to address the relaxed urinary tract.
- Trial name
- TVT/ULP (NCT07484321)
- Testing
- Transvaginal tape, Urethral ligament plication
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Sanliurfa Education and Research Hospital
HIV Infections
An Escalating Dose Tolerance Trial of BG8962 (rCD4) in Patients Who Are HIV Antibody Positive
To determine the maximal safe daily dose of BG8962 (rCD4) which can be administered by continuous subcutaneous infusion (CSCI) over 24 hours; to determine the pharmacokinetics of BG8962 when it is administered by intramuscular…
- Trial name
- NCT00000721
- Testing
- CD4 Antigens
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Dietary Modification, Kidney Diseases, Chronic
Metabolomics for Identifying Biomarkers of Dietary Intake and Kidney Disease Progression
The present record represents a secondary data analysis of the Modification of Diet in Renal Disease (MDRD) Study. For this analysis, the MDRD study data and specimens were retrieved from the National Institute of Diabetes and…
- Trial name
- MDRD (NCT03202914)
- Testing
- Usual protein and phosphorus diet, Low protein and phosphorus diet, Very low protein and phosphorus
- Where
- United States
- Volunteers
- 840 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
End Stage Renal Disease
A Guided Meditation Program in Patients Undergoing Dialysis
This is an open-label, single center, non-randomized, single-arm pilot study to determine the ability of a Relaxation and Guided Imagery Program for its ability to induce a reduction in anxiety in subjects undergoing hemodialysis…
- Trial name
- NCT04155216
- Testing
- Relaxation and guided imagery program
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The Rogosin Institute
Cardiovascular Disease, Hyperhomocysteinemia
Prevalence Of Hyperhomocysteinemia In Thai Chronic Kidney Disease (CKD) Patients
It is well recognized that patients with chronic kidney disease (CKD) have an increased risk for cardiovascular disease (CVD) and hyperhomocysteinemia appears to be a predictor of future CVD events.
- Trial name
- NCT01391416
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Bangkok Metropolitan Administration Medical College and Vajira Hospital
Prostate Cancer, Leukemia
Natural History Study of Early Life Exposures in Agriculture (ELEA)
Study Description: ELEA is an observational cohort study that will collect exposure information and biospecimens from the adult children of the Agricultural Health Study (AHS) cohort (https://aghealth.nih.gov/about; Protocol…
- Conditions
- Prostate Cancer, Leukemia, Breast Cancer, Melanoma
- Trial name
- NCT07328516
- Where
- United States
- Volunteers
- 64,277 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Kidney Failure, Respiratory Failure
Observational Study of Blood Pressure Measurements and Continuous Dialysis
Dialysis is used to control the fluid balance and metabolic state of patients with kidney disease. Control of the metabolic state, via electrolytes, can be monitored using labs that are routinely drawn from patients undergoing…
- Conditions
- Kidney Failure, Respiratory Failure, Critical Illness, Shock
- Trial name
- NCT01286506
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Chicago
Ovarian Neoplasms, Colorectal Neoplasms
An Analysis of the Response of Human Tumor Microvascular Endothelium to Ionizing Radiation
Doctors will take some tissue from the tissue removed during surgery in order to study how the blood vessels of the tumor respond to radiation therapy.
- Conditions
- Ovarian Neoplasms, Colorectal Neoplasms, Melanoma, Small Cell Lung Cancer
- Trial name
- NCT00132704
- Testing
- Ionizing radiation (IR) therapy, Ionizing radiation (IR)
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bronchopulmonary Dysplasia (BPD)
Late Low-Dose Dexamethasone in Preterm Neonates Using DART Protocol
Premature babies, especially those who need breathing support for many days, are at risk of developing a long-term lung condition called bronchopulmonary dysplasia (BPD).
- Trial name
- NCT07904104
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 93 people
- Sponsor
- Shaheed Zulfiqar Ali Bhutto Medical University
Epithelial Ovarian Cancer, Sentinel Lymph Node Detection
The Application of Sentinel Lymph Node Mapping Technique in the Surgery of Early Epithelial Ovarian Cancer
This study is a single-arm, open, multicenter, exploratory clinical study to evaluate the feasibility, sensitivity, and specificity of sentinel lymph node (SLN) mapping technology in the population with early epithelial ovarian…
- Trial name
- NCT06673511
- Testing
- Lymph node visualization, No visualization of lymph nodes
- Volunteers
- 246 people
- Sponsor
- Anhui Provincial Hospital
Ovarian Neoplasms, Ovary Cancer
Improved Diagnosis of Ovarian Cancer by Use of Circulating Tumor DNA as a Biomarker
This project investigates circulating tumor DNA (ctDNA) in patients with suspected ovarian malignancy. We hypothesize that measurement of ctDNA in women with suspected ovarian cancer can improve the diagnostic efficiency for…
- Conditions
- Ovarian Neoplasms, Ovary Cancer, Ovarian Cysts
- Trial name
- NCT05763511
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- University of Aarhus
Musculoskeletal Manipulations, Primary Prevention
Effects of Perineal Massage (PERMAS)
Perineal massage increases elasticity of myofascial perineal tissue and decreases the burning and perineal pain during labour, thus optimizing child birth, although an application protocol has not been standardized yet.
- Conditions
- Musculoskeletal Manipulations, Primary Prevention, Obstetric Labor Complications, Physical Therapy Modalities
- Trial name
- PERMAS (NCT05114811)
- Testing
- Self-provided perineal massage, Physiotherapist perineal massage: manual and instrumental (with EPI-NO)
- Where
- Spain
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Universidad de León
BPH, Benign Prostatic Hyperplasia
Moxibustion as an Adjuvant for Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms: a Pilot Study
This study aims to explore the feasibility of moxibustion as a supplementary intervention and to assess the sample size for verifying the effectiveness and safety of integrative treatment involving moxibustion compared with…
- Conditions
- BPH, Benign Prostatic Hyperplasia, Benign Prostatic Hypertrophy, Lower Urinary Tract Symptom
- Trial name
- NCT02051036
- Testing
- Moxibustion
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- JUNGNAM KWON
Premature Birth
Assessment of Autonomic Regulation During the Listening of Mother Heart Beat in Newborns
Prematurity birth lead to an early breaking link with the in utero environment. A special attention is brought in the neonatal intensive care units to reduce noise and lighting surrounding aiming to protect the newborn.
- Trial name
- Cardio_Sound (NCT04821011)
- Testing
- electronic stethoscope, acoustic listening of mother's heartbeats, Recording of the newborn's heart rate
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
HIV Infections, Acquired Immunodeficiency Syndrome
Vicriviroc in HIV-Treatment Experienced Subjects (Study P04405AM5)
Vicriviroc (vye-kri-VYE-rock) is an investigational drug (not yet approved by Government Regulatory Authorities for commercial use) that belongs to a new class of drugs, called CCR5 receptor blockers.
- Trial name
- NCT00523211
- Testing
- Vicriviroc
- Volunteers
- 506 people
- Sponsor
- Merck Sharp & Dohme LLC
HIV (Human Immunodeficiency Virus), Pain
Auricular Point Acupressure for Pain
The goal of this pilot clinical trial is to learn whether auricular point acupressure (APA) can help reduce chronic musculoskeletal pain in adults age 50 and older who are living with HIV.
- Trial name
- NCT07852611
- Testing
- Auricular Point Acupressure
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dan Song
Epithelial Ovarian Cancer, Acute Kidney Injury Due to Circulatory Failure
Effect of Sodium Thiosulfate on Nephrotoxicity of Cisplatin Intraperitoneal Heat-perfusion Chemotherapy
Ovarian cancer is the most lethal malignancy of the female genital tract. Cytoreductive surgery combined with chemotherapy is the primary treatment for ovarian cancer, and radical tumor resection is an important means to improve…
- Trial name
- NCT05877911
- Testing
- Sodium Sulfate, Hydration, Cisplatin
- Volunteers
- 110 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
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