Clinical trials: Disinfection
Normal Physiology
Effect of Genetic Differences on Levels of Water Disinfection Byproducts in Blood After Showering
This study will examine whether genetic differences among individuals affect blood levels of certain chemicals called DBPs after showering. Chemicals such as chlorine and ozone are used to kill germs in water.
- Trial name
- NCT00340535
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- National Cancer Institute (NCI)
Hand Disinfection
The Antiseptic Outcome of Traditional Hand Scrubbing Versus Hand Rubbing in Surgical Room
Hand hygiene is the cornerstone of aseptic techniques to reduce surgical site infection. The traditional surgical antisepsis involves scrubbing the skin with povidone-iodine or chlorhexidine gluconate.
- Trial name
- NCT02294604
- Testing
- ethyl alcochol, chlorhexidine and moisturizers, chlorhexidine, povidone-iodine
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Symptomatic Irreversible Pulpitis
Postoperative Pain Intensity After Pulpotomy
Introduction: This study aimed to compare postoperative pain rates following sodium hypochlorite (NaOCl) and KTP laser-assisted pulpotomy treatments in permanent teeth with deep caries, and symptomatic irreversible pulpitis.
- Trial name
- NCT05424796
- Testing
- Physiological saline, Hemostasis and cavity disinfection with NaOCl, Hemostasis and cavity disinfection with KTP laser
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Covid-19, Drug Effect
New Treatment for COVID-19 Using Ethanol Vapor Inhalation .
Since ARDS is a major complication of COVID - 19 with subsequent formation of non-cardiogenic pulmonary edema , worsening the oxygenation of the patients and foamy and even bloody sputum formation, so the idea is to use alcohol…
- Trial name
- NCT04554433
- Testing
- Ethanol with Asprin
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Hand Disinfection
Nudging Handwashing: a Cluster-randomized Trial in Bangladesh
The study will collect and analyze quantitative data regarding handwashing behaviors among school-aged children to determine the impact of nudges compared to handwashing and hygiene education programs.
- Trial name
- NCT02703974
- Testing
- Early handwashing station, Late handwashing station, Nudge
- Where
- Bangladesh
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Post-Surgical Contamination of Rigid Endoscopic Instruments
Cleaning Efficacy of Pulsed Vacuum Device on Rigid Endoscopic Instruments
This study is a prospective, comparative trial designed to evaluate the cleaning effectiveness of a novel pulsed vacuum cleaning and disinfection device against a conventional vacuum ultrasonic cleaner for rigid endoscopic…
- Trial name
- NCT07077499
- Testing
- Pulsed Vacuum Cleaning and Disinfection Device, Vacuum Ultrasonic Cleaner
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Xue Wang
Periapical Periodontitis
Comparison of Root Canal Desinfection Protocols
Evaluate and compare the disinfecting efficacy of two supplementary antimicrobial protocols in teeth with apical periodontitis
- Trial name
- NCT07439614
- Testing
- Desinfection device, Analytical microbiological methods
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Apical Periodontitis
Efficacy of Different Disinfection Technologies in Molar Non-Surgical Retreatment
Post-treatment apical periodontitis is commonly associated with persistent intracanal infection following root canal treatment. Effective disinfection of the complex root canal system during nonsurgical retreatment remains…
- Trial name
- NCT07469150
- Testing
- GentleWave System, Conventional rotary instrumentation with passive ultrasonic irrigation
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham
Periodontitis
Study of Scaling and Root Planing With PerioWave Versus Scaling and Root Planing Alone in Chronic Periodontitis
This study is to determine whether scaling and root planing (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with SRP…
- Trial name
- NCT00297531
- Testing
- PerioWave, Scaling and Root Planing
- Where
- 4 sites in Canada
- Volunteers
- 120 people
- Sponsor
- Ondine Research Laboratories
Antibacterial Effect of Diode Laser
The Microbiological Assessment of Deep Carious Lesions After Step-wise Excavation and Diode Laser Cavity Disinfection .
This study will be conducted to assess antibacterial effect of the diode laser in deep carious cavity after step wise excavation using the bacteriological assessment method.
- Trial name
- NCT03298165
- Testing
- diode laser
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Disease, Halitosis
"Study of Halitosis in Patients With Advanced Chronic Periodontitis"
The objective of this study was to evaluate whether short-term full mouth disinfection protocol could have a greater reduction in the levels of halitosis and volatile sulfur compound or not, when compared to quadrant-wise scaling…
- Conditions
- Periodontal Disease, Halitosis, Periodontitis
- Trial name
- HACP (NCT02368678)
- Testing
- Scaling and Root Planning (SRP), Full Mouth Scaling (FMS)
- Volunteers
- 30 people
- Sponsor
- Federal University of Minas Gerais
Periodontitis
SRP in Combination With PERIOWAVE in Comparison to SRP Alone in Chronic Periodontitis
This study is to determine whether scaling and root planning (SRP) followed by photodynamic disinfection results in improved outcomes that persist over time in adults with chronic periodontitis when compared with subjects with…
- Trial name
- NCT00296881
- Testing
- PERIOWAVE
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Ondine Research Laboratories
Aggressive Periodontitis
Evaluation of Efficacy of Full-mouth Disinfection in Generalized Aggressive Periodontitis Patients
The purpose of this study is to determine whether full-mouth disinfection is effective in the initial periodontal treatment of generalized aggressive periodontitis on clinical parameters, gingival crevicular fluid interleukin-1β…
- Trial name
- NCT02466646
- Testing
- Klorhex® Gel, rinse and spray, Conventional IPT, Full-mouth IPT
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Marmara University
Dental Caries
Microbiome Changes After Laser and Chlorhexidine Disinfection in Caries Removal
The aim of this study was to investigate the effects of cavity disinfection with laser and chlorhexidine on the microbiome in cavities prepared using different caries removal methods.
- Trial name
- NCT06765330
- Testing
- CHX disinfection, Laser Disinfection, Tungsten carbide bur
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Mersin University
Infected Immature Permanent Teeth
Regenerative Endodontic Therapy (RET) for the Management of Immature Non-vital Permanent Teeth in Children
This study evaluates the efficacy of Antibiotic pastes or Calcium hydroxide disinfection on healing of periapical pathology and continued root development of infected non-vital immature permanent teeth in children.
- Trial name
- NCT03327844
- Testing
- RET using antibiotics (Ciprofloxacin and Metronidazole), RET using non-setting Calcium Hydroxide
- Where
- 2 sites in Singapore
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University Health System, Singapore
Uncontrolled Type 2 Diabetes Mellitus, Severe Periodontitis
A Comparison of Single-Stage Full-Mouth Disinfection With Quadrant-Based Scaling and Root Planing in Patients With Uncontrolled Type 2 Diabetes and Severe Periodontitis: An Assessment of Its Impact on Quality of Life
This study evaluated the effects of a single-stage full mouth disinfection (FMD) protocol versus a quadrant-based tooth surface cleaning and root planing (Q-SRP) protocol on changes in clinical periodontal parameters over a…
- Trial name
- NCT07598071
- Testing
- Quadrant based scaling and root planning, full mouth disinfeciton
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Pamukkale University
Hygiene
Reducing Visitors- and Personnel-associated Infection Risk on Perinatal Care Station
The rate of infectious diseases (amnioninfection syndrome (AIS), fetal inflammatory response syndrome (FIRS), early-onset neonatal sepsis (EONS)) in perinatal care / neonatology is steadily rising in Germany.
- Trial name
- NCT03032887
- Testing
- voice prompts, agitation
- Where
- Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Dysentery, Diarrhoea
Solar Disinfection (SODIS) of Drinking Water for Use in Developing Countries or in Emergency Situations
SODISWATER was a health impact assessment study investigating the effect of sunlight to inactivate microbial pathogens in drinking water.
- Trial name
- SODISWATER (NCT01306383)
- Testing
- SODIS Bottle
- Where
- 3 sites in Cambodia, Kenya and 1 more
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- Royal College of Surgeons, Ireland
Rheumatoid Arthritis
Full Mouth Disinfection and Antibiotics for Periodontitis in High or Moderate Disease Activity Rheumatoid Arthritis
The purpose of this study is to determine whether full mouth disinfection in combination with one week antibiotic amoxicillin plus metronidazole antibiotic therapy is improving periodontitis and disease activity of rheumatoid…
- Trial name
- FMD-ABRA (NCT02096120)
- Where
- Switzerland
- Volunteers
- 8 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Apical Periodontitis
Assessment of Different Disinfection Protocols on Regenerative Potential of Mature Teeth
Regenerative endodontic procedures have been used to successfully treat human mature permanent teeth with necrotic pulps and apical periodontitis.
- Trial name
- NCT05557994
- Testing
- Method
- Where
- Egypt
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Minia University