Clinical trials: Disk Herniated Lumbar
Disk Herniated Lumbar, Disc Disease Degenerative
Clinical Outcome and Fusion Rate of 3D Printed Interbody Fusion Cages and Titanium Coated PEEK Cages
Prospective, Randomized, Single-Blind Study for the Evaluation of the Clinical Outcome and the Fusion Rate of 3D Printed Interbody Fusion Cages and Titanium Coated PEEK Cages in Transforaminal Lumbar Interbody Fusion
- Conditions
- Disk Herniated Lumbar, Disc Disease Degenerative, Spondylolisthesis
- Trial name
- PRINTLIF (NCT05237908)
- Testing
- Transforaminal Lumbar Interbody Fusion
- Where
- Germany
- Volunteers
- 78 people
- Sponsor
- Aesculap AG
Analgesia, Disk Herniated Lumbar
Analgesia Following Lumbar Discectomy
Lumbar discectomy surgeries are often the last option for patients with disc herniation who do not improve with conservative treatments.
- Conditions
- Analgesia, Disk Herniated Lumbar, Local Infiltration
- Trial name
- NCT06869889
- Testing
- Retrolaminar plane block, Local wound infiltration
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Zagazig University
Lumbar Radiculopathy, Lumbar Herniated Disk
Does Intraoperative Application of Steroids Affect Early Outcomes in Patients Undergoing Endoscopic Lumbar Discectomy?
Prospective randomised trial assessing whether intraoperative application of steroids leads to better clinical outcomes in patients submitted to lumbar discectomy
- Trial name
- NCT07411326
- Testing
- Intervention Group, Control group (Normal Saline) (C)
- Where
- Portugal
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Disc Herniation, Disk Herniated Lumbar
Safety And Performance Of Disc Care To Prevent Lumbar Disc Herniation Recurrence
The goal of this clinical investigation is to learn about DISC Care, an Hernia Blocking System, in patients who have undergone lumbar disc hernia surgery.
- Trial name
- ACE-2 (NCT06023719)
- Testing
- DISC Care
- Where
- 7 sites in Spain
- Volunteers
- 30 people
- Sponsor
- NEOS Surgery
Back Pain With Radiation, Radiculopathy
Lumbar Operatively Inserted PerQdisc Artificial Implant Following Nuclectomy 3
This study is a First in Human, prospective, multi-center clinical study intended to collect safety and performance information for the Spinal Stabilization Technologies PerQdisc® Nucleus Replacement System and procedure…
- Conditions
- Back Pain With Radiation, Radiculopathy, Back Pain, Disc Herniation
- Trial name
- LOPAIN3 (NCT05732818)
- Testing
- PerQdisc Nucleus Replacement System
- Where
- 2 sites in Paraguay, Uzbekistan
- Volunteers
- 50 people
- Sponsor
- Spinal Stabilization Technologies
Herniated Disk Lumbar, Metabolic Syndrome
Effect of Metabolic Syndrome on Outcomes of Transforaminal Epidural Steroid Injection Treatment in Chronic Lumbar Radiculopathy
Transforaminal epidural steroid injection (TFESI) has been increasingly preferred in patients who can not benefit from conservative approach in the treatment of lumbosacral radiculopathic pain due to lumbar disc herniation.
- Trial name
- NCT05088954
- Testing
- transforaminal epidural steroid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Marmara University
Disk Herniated Lumbar
Efficacy and Safety of IntraSPINE® Associated With Discectomy in the Treatment of Lumbar Disc Herniation.
IntraSPINE® is a novel device that, unlike interspinous positioned implants, is unique in being placed more anteriorly in an interlaminar position, closer to the normal center of rotation of the motion segment.
- Trial name
- INTREUR (NCT03752671)
- Testing
- Insertion of INTRASPINE device, Discectomy
- Where
- France
- Volunteers
- 199 people
- Sponsor
- Quanta Medical
Posterolateral Disc Herniation L4-L5-S1, Disk Herniated Lumbar
Ultrasound-guided Percutaneous Electrolysis Compared to Placebo Acupuncture in Posterolateral Lumbar Disc Herniation
Lumbar discopathies are among the most common medical concerns in Europe and Spain. Globally, around 2-3% of the population is affected by this condition, which manifests as tingling, burning, itching, muscle weakness, limb pain…
- Trial name
- NCT06569069
- Testing
- US guided PE
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad de Zaragoza
Lumbar Herniated Disk
The Use of a Patient Decision Aid in the Choice of Surgery for Herniated Disc
Even though surgery due to lumbar disc herniation (LDH) shows a more rapid relief of pain and recovery, the evidence of surgery being superior to conservative treatment in the long term is inconclusive.
- Trial name
- NCT03884387
- Testing
- Patient Decision Aid
- Where
- Denmark
- Volunteers
- 142 people
- Sponsor
- Spine Centre of Southern Denmark
Low Back Pain, Radiculopathy Lumbar
Efficacy of Transforaminal Epidural Steroid and Its Combination With Ozone in Lumbar Radiculopathy
This retrospective study aimed to assess the clinical effectiveness and safety of transforaminal epidural injections of steroid and ozone mixture versus steroid alone in low back and radicular leg pain related to disk herniation.
- Conditions
- Low Back Pain, Radiculopathy Lumbar, Hernia, Disk Herniated Lumbar
- Trial name
- NCT06503835
- Testing
- Fluoroscopy Guided Transforaminal Epidural Ozone Injection, Fluoroscopy Guided Transforaminal Epidural Steroid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ibn Sina Hospital
Herniated Lumbar Disk
Confirmatory Clinical Study of Oxiplex
This is a prospective, multi-center, randomized, controlled, patient and evaluator-blinded clinical study to assess the safety and effectiveness for the reduction of pain and symptoms following lumbar surgery.
- Trial name
- NCT03433391
- Testing
- Oxiplex, Surgery Only
- Where
- 17 sites in United States
- Volunteers
- 135 people
- Sponsor
- FzioMed
Herniated Disk Lumbar
Evaluation of Plenum® Tissue Ortho to Prevent Epidural Fibrosis and Post-laminectomy Syndrome.
The goal of this clinical trial is to compare if adding a polydioxanone membrane prevents epidural fibrosis and, consequently, the rate of occurrence of the post-laminectomy syndrome in participants undergoing microdiscectomy for…
- Trial name
- NCT05776628
- Testing
- Plenum® Tissue ortho membrane (polydioxanone membrane)
- Where
- Brazil
- Volunteers
- 36 people
- Sponsor
- M3 Health
Disk Herniated Lumbar
EHR Embedded Comparative Effectiveness Studies--CPS
Randomize Everyone is a research project to develop new informatics systems and statistical methods for supporting randomization processes in EHR systems to do comparative effectiveness research.
- Trial name
- EHR-CPS (NCT04520009)
- Testing
- Activity Restriction, Activity as Tolerated
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Herniated Disk Lumbar
Return to Work After Early Intervention for Lumbar Disc Herniation Versus Usual Care
The most common cause of low back pain with radiculopathy among the working population is a Lumbar Disc Herniation (LDH). In general, the natural history of sciatica is favourable with spontaneous remission.
- Trial name
- WILD (NCT04657354)
- Testing
- Assessment
- Sponsor
- Spine Centre of Southern Denmark
Radiculopathy, Low Back Pain, Mechanical
Efficacy of Ultrasound Versus Short Wave Diathermy in the Treatment of a Slipped Disc of the Lower Back
Chronic low back pain is a common problem which results in reduced functionality, quality of life and general well being. Conservative treatment includes patient education, exercise, maintaining a healthy body mass index and…
- Conditions
- Radiculopathy, Low Back Pain, Mechanical, Herniated Disk Lumbar
- Trial name
- NCT03835182
- Testing
- Ultrasound group, Short wave diathermy group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Baskent University
Disk Herniated Lumbar
Safety and Performance of a Hernia Blocking System
Prospective, multi-center, single-arm clinical study to assess the performance of an Hernia Blocking System in preventing clinically symptomatic recurrent lumbar disc herniation.
- Trial name
- NCT04188236
- Testing
- Hernia Blocking System
- Where
- 6 sites in Spain
- Volunteers
- 30 people
- Sponsor
- NEOS Surgery
Anesthesia, Disk Herniated Lumbar
Effects of Different Types of Anaesthesia on Intraocular Pressure During Lumbar Disc Herniation Surgery
The aim of this study was to investigate the effects of anaesthesia methods on intraocular pressure during lumbar disc surgery performed in the prone position.
- Conditions
- Anesthesia, Disk Herniated Lumbar, Intraocular Pressure
- Trial name
- NCT06070480
- Testing
- Spinal Anesthesia Group, Desflurane Group, Propofol Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Disk Herniated Lumbar, Radicular Pain
Percutaneous Intradiscal Radiofrequency as A Treatment for Radicular Pain From Lumbar Disc Herniation
The goal of this clinical trial is to demonstrate the efficacy of percutaneous intradiscal radiofrequency as a treatment for radicular pain from lumbar disc herniation.
- Conditions
- Disk Herniated Lumbar, Radicular Pain, Intradiscal Radiofrequency
- Trial name
- NCT05747807
- Testing
- Percutaneous intradiscal radiofrequency treatment
- Where
- Thailand
- Volunteers
- 18 people
- Sponsor
- Chulalongkorn University
Intervertebral Disc Displacement, Disk Herniated Lumbar
Is Regression Possible in Lumbal Disc Herniation With Spinal Mobilization Applications?
Spinal mobilization methods are passive maneuvers that are made lighter and do not exceed the physiological range of motion in order to increase joint mobility.
- Conditions
- Intervertebral Disc Displacement, Disk Herniated Lumbar, Disc Herniation
- Trial name
- NCT05753579
- Testing
- Spinal Mobilization, Stabilization Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Muş Alparslan University
Disk Herniated Lumbar
Compare Effects of Ultrasound Therapy With High Intensity Laser Therapy for Treatment of Lumbar Disc Herniation.
The aim of this study is to assess and compare the effects of ultrasound therapy and High Intensity Laser Therapy, as the treatment option in case of lumbar disc herniation.
- Trial name
- NCT05261815
- Testing
- Ultrasound Therapy, High Intensity Laser Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University