Clinical trials: Disk Prolapse
Lumbar Disc Herniation, Obstructive Sleep Apnea Risk Management
Daytime vs Evening Rehabilitation in Lumbar Disc Herniation Patients at High Risk for Obstructive Sleep Apnea
Lumbar disc herniation is a common musculoskeletal condition that negatively affects quality of life, physical function, and daily activities.
- Trial name
- REHAB-TIME (NCT07522021)
- Testing
- Physiotherapy and Exercise Program
- Volunteers
- 60 people
- Sponsor
- Mardin Artuklu University
Lumbar Disc Degeneration, Lumbar Disc Disease
Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement
Lumbosciatica is a very prevalent pathology. When conservative treatments fail, surgery should be considered. The traditional surgical treatment is lumbar arthrodesis.
- Conditions
- Lumbar Disc Degeneration, Lumbar Disc Disease, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06989632
- Testing
- Total lumbar disc prosthesis (Baguera®L, Spineart, Switzerland)
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- University of Valencia
Return to Work, Musculoskeletal Disease
Contact to a Physician Specialized in Social Medicine and Return to Work
The aim of this study was to investigate the impact of a rehabilitation program including a physician specialized in social medicine parallel to treatment for suspected spinal disc herniation.
- Trial name
- NCT03010384
- Testing
- Rehabilitation program
- Volunteers
- 443 people
- Sponsor
- Kirsten Fonager
Disc Herniation, Surgery
Exercise After Lumbar Disc Herniation Surgery
Physical therapy and rehabilitation may improve low back pain and quality of life after lumbar disc herniation. But there is not any agreement of its optimal start time, and rehabilitative methods.
- Trial name
- NCT06046781
- Testing
- physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 204 people
- Sponsor
- Istanbul Medeniyet University
Cervical Disc Herniation
Sensory and Functional Impairments in Cervical Disc Herniation
The aim of the study was to evaluate the levels of somatosensory perception, pain threshold and kinesiophobia in individuals with SDH, to examine their relationship with upper extremity functional skills and to compare them with…
- Trial name
- NCT07282522
- Testing
- Somatosensory Perception Tests, The Visual Analog Scale, Pain Threshold and Tolerance Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Inonu University
Radiculopathy
The Effectiveness of Selective Nerve Root Injections in Preventing the Need for Surgery
The median Orthopaedic surgery wait time in Canada is 36.7 weeks (Esmail 2008), thus there is a need to find alternative treatments for pathologies such as lumbar disc herniations (LDH).
- Trial name
- NCT01073995
- Testing
- Kenalog and Sensorcaine
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- Horizon Health Network
Prolapse
Rehabilitation After Lumbar Disc Surgery: Exercise Therapy and Brief Educational Intervention
Rehabilitation after lumbar disc surgery (prolapse) focuses on various elements such as endurance, strength, stretching and information.
- Trial name
- NCT01779544
- Testing
- Brief intervention, an educational model, Exercise therapy
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Haukeland University Hospital
Low Back Pain, Spondylolisthesis
Lumbar Interbody Fusion Using the Telamon® Peek™ Versus the Telamon® Hydrosorb™ Fusion Device
Lumbar spinal fusion is commonly performed as a "last resort" in patients with chronic low back pain caused by degenerative changes and instability of the spine.
- Conditions
- Low Back Pain, Spondylolisthesis, Spinal Stenosis, Intervertebral Disc Displacement
- Trial name
- NCT00095095
- Testing
- Lumbar Interbody Fusion
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 102 people
- Sponsor
- Medtronic Spinal and Biologics
Degenerative Disc Disease
Viable Allograft Supplemented Disc Regeneration in the Treatment of Patients With Low Back Pain
The objective of this study is to evaluate the safety and efficacy of viable allograft transplantation for the treatment of patients with symptomatic disc degeneration and tissue loss.
- Trial name
- VAST (NCT03709901)
- Testing
- Active Allograft
- Where
- 13 sites in United States
- Volunteers
- 218 people, healthy volunteers welcome
- Sponsor
- VIVEX Biologics, Inc.
Lumbar Intervertebral Disc Displacement, Cervical Intervertebral Disc Displacement
Disc Resorption in Lumbar and Cervical Disc Herniation Patients Receiving Integrative Korean Medicine Treatment
Measurement of herniated disc resorption and assessment of satisfaction regarding post-treatment state and integrative Korean medicine treatment through phone interview in 500 patients with MRI follow-up results receiving…
- Trial name
- NCT02841163
- Testing
- Herbal medicine, Acupuncture, Pharmacopuncture
- Where
- South Korea
- Volunteers
- 505 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation
STA363 in the Treatment of Lumbar Disc Herniation
The goal of this clinical trial is to establish safety and tolerability of STA363 injected into a herniated intervertebral disc in patients with sciatica due to disc herniation. The main questions the trial aims to answer are: 1.
- Trial name
- NCT06022263
- Testing
- Lactic Acid
- Where
- Poland
- Volunteers
- 25 people
- Sponsor
- Stayble Therapeutics
Radiculopathy, Lumbosacral Region, Radiculopathy Lumbar
The Effect of High-power Laser Therapy on Pain, Functional Disability, Range of Motion and Pressure Pain Threshold in Subjects With Radicular Low Back Pain Due to Intervertebral Disc Herniation
Low back pain is the predominant cause of disability on a global scale. In the year 2015, the worldwide point prevalence of activity-limiting low back pain stood at 7·3%, suggesting that at any given moment, 540 million…
- Trial name
- NCT06151704
- Testing
- High intensity laser therapy, Motor control exercise
- Where
- Iran
- Volunteers
- 36 people
- Sponsor
- Iran University of Medical Sciences
Symptomatic Lumbar Disc Herniation, Symptomatic Grade I Lumbar Spondylolisthesis
Neurosurgery Patient Outcomes in Treating Spinal Disorders
The creation of a multi-center cooperative research group encompassing academic and community-based spinal practices . . .
- Trial name
- Neuropoint SD (NCT01220921)
- Testing
- Lumbar Discectomy, Single-level lumbar fusion
- Where
- 13 sites in United States, Canada
- Volunteers
- 198 people
- Sponsor
- Greenwich Hospital
Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy
TFESI and Neuropathic Pain in Lumbosacral Radiculopathy
Patients with lumbosacral radiculopathy frequently experience neuropathic pain due to nerve root compression. Transforaminal epidural steroid injection (TFESI) is commonly used for pain relief in these patients.
- Conditions
- Lumbosacral Radiculopathy, Neuropathic Pain From Lumbosacral Radiculopathy, Disc Herniation With Radiculopathy
- Trial name
- NCT07799155
- Testing
- Transforaminal Epidural Steroid Injections
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Marmara University
Lumbar Spondylosis, Lumbar Spinal Stenosis
Modified Enhanced Recovery After Oblique Lateral Interbody Fusion Surgery
The goal of this randomized clinical trial is to investigate whether modified enhanced recovery after surgery (ERAS) in oblique lumbar interbody fusion (OLIF) can shorten the postoperative hospital stay among patients with lumbar…
- Conditions
- Lumbar Spondylosis, Lumbar Spinal Stenosis, Lumbar Disc Herniation
- Trial name
- MERAOLIS (NCT05854043)
- Testing
- Modified ERAS protocol, routine protocol
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Xuanwu Hospital, Beijing
Low Back Pain, Sciatica
Long-Term Course of Korean Medicine Treatment for Lumbar Disc Herniation
This observational study will assess the long-term course and effect of Korean medicine treatment in lumbar intervertebral disc herniation patients who received integrative Korean medicine treatment for 24 weeks as part of a…
- Conditions
- Low Back Pain, Sciatica, Intervertebral Disc Displacement
- Trial name
- NCT03426215
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- South Korea
- Volunteers
- 65 people
- Sponsor
- Jaseng Medical Foundation
Lumbar Disc Herniation, Radiculopathy Lumbar
Efficacy and Safety of Electroacupuncture on Lumbar Disc Herniation with Radiculopathy
Lumbar disc herniation with radiculopathy (LDHR) is the local displacement of the intervertebral disc and its contents beyond the edge of the normal intervertebral disc space, resulting in pain, weakness or numbness in the muscle…
- Trial name
- NCT06611332
- Testing
- Electroacupuncture
- Where
- China
- Volunteers
- 170 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Cervical Disc Herniation, Intervertebral Disc Displacement
Gelified Radiopaque Ethanol (Absolute Gel) in Cervical Disc Herniation: an Observational Study in Routine Clinical Practice (GENESIS)
GENESIS is a single-centre, observational, non-interventional, no-profit, investigator-initiated study conducted at Ospedale di Vimercate, ASST Brianza (Italy).
- Conditions
- Cervical Disc Herniation, Intervertebral Disc Displacement, Neck Pain, Chronic Pain
- Trial name
- GENESIS (NCT07832929)
- Testing
- Absolute Gel (radiopaque gelified ethanol)
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- Aurel Mengri
Lumbar Disc Herniation
Exploring the Distribution Patterns and Infrared Characteristics of Force-sensitive Acupoints in Different Lumbar Nerve Segments in Patients With LDH Based on "Press Quickly" Theory
Utilizing the "responsive acupoint palpation" technique and infrared thermography, we investigated the distribution patterns of pressure-sensitive acupoints across different lumbar spinal segments in patients with lumbar disc…
- Trial name
- NCT06318156
- Testing
- Infrared thermal imaging
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zhou Xingchen
Intervertebral Disc Displacement, Spinal Stenosis Lumbar
Artificial Intelligence Enabled Decision Support for Selection of Patients for Lumbar Spine Surgery
Background One third of patients operated for lumbar disc herniation (LDH) or spinal stenosis (LSS) do not achieve substantial improvement.
- Conditions
- Intervertebral Disc Displacement, Spinal Stenosis Lumbar, Lumbar Disc Herniation, Lumbar Spine Degeneration
- Trial name
- NCT06806969
- Testing
- Decision support
- Where
- Norway
- Volunteers
- 26 people
- Sponsor
- University Hospital of North Norway