Clinical trials: Disorder, Mood
Seasonal Mood Disorder
Vitamin D Supplementation and Effects on Mood in Emergency Medicine Residents
Seasonal mood changes, and even feelings of depression, appear to have an association with decreased amounts of vitamin D in people living in geographic areas where exposure to sunlight during the winter months is relatively low.
- Trial name
- NCT03739671
- Testing
- Vitamin D, No Vitamin D
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Corewell Health South
Mood
Sub-chronic Effects of 5-hydroxytryptophan on Mood and Emotional Processing in Healthy Volunteers
5-hydroxytryptophan (5-HTP) is a nutritional supplement sold in many health food stores, and is taken in order to raise levels of serotonin in the brain. Serotonin is a neurotransmitter that is involved in the regulation of mood.
- Trial name
- NCT01514409
- Testing
- 5-Hydroxytryptophan, Pharmaceutical grade silica
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Depression, Anxiety
Effects of Probiotics on Mood
Recent demonstration that probiotics administration has positive effects on depressive feelings in healthy populations suggests its possible role as an adjuvant therapy for depression in clinical populations and as a non-invasive…
- Trial name
- NCT03539263
- Testing
- Bifihappy
- Where
- Italy
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Probiotical S.p.A.
Depression, Anxiety
Cognitive Behavioral Therapy Versus Ericksonian Hypnosis Therapy for Depression and Anxiety Symptoms
Title: Comparison of Cognitive Behavioral Therapy and Ericksonian Hypnosis Therapy for Depression and Anxiety Symptoms; A Controlled Randomized Study. Principal Investigator: Dr.
- Trial name
- NCT06484400
- Testing
- Cognitive Behavioral Therapy, Ericksonian Hypnotehrapy
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Istanbul Nisantasi University
Major Depressive Disorder
Prospective Clinical Cohort Study of Depression
This is a prospective clinical cohort study of depression. The study was intended to include 300 patients with depression and 100 healthy controls.
- Trial name
- NCT05775809
- Testing
- selective serotonin reuptake inhibitors, TMS
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Cognitive Impairment, Mood Disorders
Performances of a Brief Assessment Tool for the Early Diagnosis of Geriatric Syndromes by Primary Care Physicians
The AGE (Active Geriatric Evaluation) aims to develop a brief assessment tool adapted to the primary care setting.
- Conditions
- Cognitive Impairment, Mood Disorders, Urinary Incontinence, Malnutrition
- Trial name
- NCT01816087
- Testing
- brief geriatric assessment
- Where
- Switzerland
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- University of Lausanne
Depression Disorders, Affective Disorders
Prevention of Mental Disorders Through Self-efficacy Interventions
Low self-efficacy is a transdiagnostic risk factor for several mental disorders. Self-efficacy refers to one's belief that one is capable of performing a behavior necessary to successfully complete a task or achieve a goal.
- Conditions
- Depression Disorders, Affective Disorders, Prevention, Substance Use Disorders
- Trial name
- SELFTIE (NCT06738953)
- Testing
- Cognitive-Behavioral Intervention to increase Self Efficacy
- Where
- Germany
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Health and Medical University Potsdam
Major Depressive Disorder
Tracking Brain Biomarkers and Renormalization Associated With Antidepressant Transcranial Magnetic Stimulation Therapy
This study will attempt to use magnetic resonance imaging (MRI) to take a picture of the brain to learn about changes that occur in the brain during Transcranial Magnetic Stimulation (TMS) in people receiving this treatment for…
- Trial name
- INSCAPE (NCT06043401)
- Testing
- Neuroimaging with Magnetic Resonance Imaging (MRI)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Obesity
Mindful Eating and Living for Obese Women
Background: Mindfulness-based interventions may be effective in reducing the stress that may increase both obesity and inflammation.
- Trial name
- MEAL (NCT02753972)
- Testing
- Mindful Eating and Living, Active Weight Loss Control
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Depression, Involutional
Function of Catecholamines in the Brain During Depression
This study will explore brain function related to depressive symptoms and will examine DNA for genes that may be involved in depressive disorders, particularly genes that regulate synthesis and metabolism of the brain…
- Trial name
- NCT00082030
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Major Depressive Disorder
Evaluation of the Effects of Duloxetine on Norepinephrine
The purpose of this study is to evaluate how taking duloxetine 60mg every day affects the transfer of two normal body chemicals, 3,4-dihydroxyphenylglycol (DHPG) and norepinephrine (NE), across cells in blood and cerebrospinal…
- Trial name
- NCT00414323
- Testing
- Duloxetine, Escitalopram
- Where
- 2 sites in United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Depressive Disorder, Anxiety Disorder
Cost- Effectiveness Study of Brief Interventions for Mood and Anxiety Disorders
This study compares both clinical effectiveness and cost-effectiveness of a brief, intensified therapy and diagnostic method for patients with mood and/or anxiety disorders with Treatment As Usual (TAU) at five outpatient Mental…
- Trial name
- K&K (NCT01643642)
- Testing
- Cognitive behavioral treatment/farmacotherapy intervention, Treatment As Usual
- Where
- Netherlands
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Postpartum Urinary Incontinence, Postpartum Depression (PPD)
Prenatal Exercise Including Perineal Massage and Maternal-Neonatal Outcomes
The study is divided into three phases: Phase 1: Baseline survey to obtain an overall understanding of the current situation of voluntary participation in prenatal perineal massage.
- Conditions
- Postpartum Urinary Incontinence, Postpartum Depression (PPD), Neonatal Complications, Gestational Diabetes
- Trial name
- PEPM-RCT (NCT07314502)
- Testing
- Supervised prenatal exercise including antenatal perineal massage
- Where
- China
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- South China Normal University
Bipolar Disorder
Study of Aripiprazole (Abilify) in Children With Symptoms of Mania
The purpose of this study is to look at the safety and effectiveness of aripiprazole (abilify) in children with bipolar disorder and to examine whether or not patients that respond to initial mood stabilization benefit from…
- Trial name
- NCT00194077
- Testing
- Aripiprazole
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Major Depressive Disorder
Effects of Ghrelin Administration on Dopamine and Effort
Ghrelin is a stomach-derived hormone and the only known circulating peptide that stimulates appetite. Animal studies have conclusively shown that ghrelin increases dopaminergic neurotransmission and, thereby, enhances effort.
- Trial name
- NCT05318924
- Testing
- Ghrelin
- Where
- Germany
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Rheumatoid Arthritis, Inflammatory Arthritis
Sleep and Exercise in Rheumatoid Arthritis
Regular physical activity is important for people with rheumatoid arthritis (RA). Sleep requirements for adults should be on a 'sleep needs spectrum' of between 7 to 9 hours per day.
- Trial name
- NCT03140995
- Testing
- Walking Programme
- Where
- Ireland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University Hospital of Limerick
Amphetamine Dependence
Dose Response of Mirtazapine to Methamphetamine Induced Interest, Mood Elevation and Reward
The primary purpose of this study is to determine if Mirtazapine will produce a decrease in interest in the drug, a decrease in mood elevation, and/or a decrease in reward when given before methamphetamine compared to placebo.
- Trial name
- NCT00600145
- Testing
- Mirtazapine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Major Depressive Disorder, Healthy Participants
A Study of the Neurobiology of Depression
Previous research studies have shown that depression is associated with changes in structure and activity in different parts of the brain and that antidepressant medication can affect brain activity in different parts of the…
- Trial name
- NCT01051466
- Testing
- Duloxetine
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Major Depressive Disorder, Mood Disorders
Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar Disorder
This trial has two studies. In study 1, the investigators will explore the relationships between three psychobiological factors (sleep patterns, motor activity, and decision-making ability).
- Conditions
- Major Depressive Disorder, Mood Disorders, Bipolar Disorder (BD)
- Trial name
- MoodCatcher (NCT07427966)
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Depression, Bipolar Disorder
Neuro-computational Study of Thymic Fluctuations in Mood Disorders
Depression and bipolar disorder are frequent, debilitating conditions. Both are thought to be primarily caused by an impaired regulation of mood, which is why they are sometimes referred to as "mood disorders".
- Conditions
- Depression, Bipolar Disorder, Recurrent Depression, Mood Disorders
- Trial name
- MOODELING (NCT07033923)
- Testing
- Brain magnetic resonance imaging (MRI) with structural (anatomical) and functional sequences (optional), Computerized cognitive tests, Daily longitudinal monitoring by mobile MOODELING application
- Where
- 2 sites in France
- Volunteers
- 588 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier St Anne
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.