Clinical trials: Disorder, Mood
Depressive Disorder
Effects of Low-dose Ketamine as an Adjunct to Propofol-based Anesthesia for Electroconvulsive Therapy
Ketamine has been used successfully as the sole medication for anesthesia in the setting of electroconvulsive therapy (ECT), and has more recently been studied as an adjunct agent in combination with propofol (the most commonly…
- Trial name
- NCT02579642
- Testing
- Ketamine
- Where
- 2 sites in Canada
- Volunteers
- 48 people
- Sponsor
- University of Alberta
Depression, Postpartum
Efficacy and Safety Study of NeuroStar TMS Therapy in Patients With Major Depressive Disorder With Postpartum Onset
The purpose of this study is to evaluate the safety and effectiveness of acute NeuroStar TMS therapy in women who have postpartum depression.
- Trial name
- NCT01842542
- Testing
- NeuroStar Transcranial Magnetic Stimulation (TMS)
- Where
- 8 sites in United States
- Volunteers
- 25 people
- Sponsor
- Neuronetics
Major Depressive Disorder
Efficacy and Safety Study of ABT-436 in Major Depressive Disorder
The purpose is to study the efficacy and safety of ABT-436 in Major Depressive Disorder.
- Trial name
- NCT01741142
- Testing
- ABT-436, Escitalopram
- Where
- 18 sites in United States
- Volunteers
- 19 people
- Sponsor
- AbbVie (prior sponsor, Abbott)
Bipolar Disorder
Study of the Genetic and Environmental Factors of Vulnerability in Bipolar Disorders
Bipolar disorder is a complex, multifactorial disorder with the intervention of genetic vulnerability factors. To help the identification of these genetic factors and to improve genotype-phenotype correlation, the identification…
- Trial name
- GAN (NCT02627404)
- Testing
- Blood sample, actometer
- Where
- France
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Bipolar Disorder (BD), Bipolar Disorder (BPD)
Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models
This preclinical translational study aims to evaluate a new method of delivering lithium using gold nanoparticles for the treatment of bipolar disorder.
- Trial name
- GLAD (NCT07732933)
- Testing
- Peripheral blood sampling for PBMC isolation
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anxiety Disorder, Affective Disorders
Doing More With Less": Optimizing Psychotherapeutic Services in the Mental Health System
Psychotherapy is one of the cornerstones of mental health services. It is provided by psychiatrist, psychologists and psychiatric social worker in both hospital and out-patient services, and is assumed to require massive manpower…
- Conditions
- Anxiety Disorder, Affective Disorders, Personality Disorders
- Trial name
- NCT03608449
- Testing
- questionnaires
- Volunteers
- 100 people
- Sponsor
- Shalvata Mental Health Center
Major Depressive Disorder
Multicomponent Yoga Intervention for Major Depressive Disorder
The purpose of this study is to evaluate the efficacy of a multi-component yoga intervention featuring Sudarshan Kriya Yoga (SKY) as an adjunctive treatment for patients with Major Depressive Disorders with incomplete response to…
- Trial name
- NCT02616549
- Testing
- Sudarshan Kriya Yoga
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pennsylvania
Breastfeeding, Postnatal Depression
Mother and Late Preterm Lactation Study
Breastfeeding has various benefits for the mother and infant. It has the capability of reducing the risk of short term and long term problems for the infant, such as gastroenteritis, respiratory infections, type II diabetes and…
- Conditions
- Breastfeeding, Postnatal Depression, Stress, Psychological, Preterm Infant
- Trial name
- MAPLeS (NCT03791749)
- Testing
- Breastfeeding Support
- Where
- United Kingdom
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University College, London
Stress Disorders, Post-Traumatic, Depressive Disorder
Whole Health in VA Mental Health: Omnis Salutis
Recent Veterans of the Afghanistan and Iraq conflicts are presenting in VA care with high rates of posttraumatic stress disorder (PTSD), depression, anxiety, and substance use disorders.
- Conditions
- Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders, Substance-Related Disorders
- Trial name
- OS RCT (NCT05400252)
- Testing
- Omnis Salutis, Health and Wellness
- Where
- 2 sites in United States
- Volunteers
- 238 people
- Sponsor
- VA Office of Research and Development
Post Partum Depression
A Study to Assess the Safety of Brexanolone in the Treatment of Adolescent Female Participants With Postpartum Depression (PPD)
This is a multi-center study evaluating the safety, tolerability, and pharmacokinetics of brexanolone in the treatment of adolescent female participants with postpartum depression (PPD).
- Trial name
- NCT03665038
- Testing
- Brexanolone
- Where
- 17 sites in United States
- Volunteers
- 28 people
- Sponsor
- Supernus Pharmaceuticals, Inc.
Major Depression
Transcranial Pulse Stimulation for Depression
Transcranial pulse stimulation (TPS) is a newly developed brain stimulation therapy from Austria \& Germany with highly promising applicability in neuropsychiatric disorders.
- Trial name
- NCT05551585
- Testing
- Transcranial pulse stimulation
- Where
- Hong Kong
- Volunteers
- 80 people
- Sponsor
- The Hong Kong Polytechnic University
Bipolar Disorder
Short Term Rescue Study of Olanzapine
We will assess the effect of olanzapine compared to placebo added to prior treatment on CGI-S in a one-week randomized double-blind study.
- Trial name
- NCT00186017
- Testing
- Olanzapine/Zyprexa
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Post Partum Depression
Access to Maternity and Risk Factors in a Non-consultant Population (PROXIMA)
Characterize the psychic and medical disorders related to pregnancy and motherhood in a group of primiparous and primigratic women.
- Trial name
- NCT04506489
- Testing
- Psychological investigation
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
End Stage Renal Disease, Depression
Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes
The objective of this study is to determine the effect of music therapy during dialysis on: depression, anxiety, quality of life, blood pressure, heart rate, medication compliance, compliance with dialysis treatment, number of…
- Conditions
- End Stage Renal Disease, Depression, Anxiety, Major Depressive Disorder
- Trial name
- NCT03925168
- Testing
- Music therapy
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Tulane University
Depressive Disorder
Evaluating the Efficacy of Magnetic Seizure Therapy in Treatment Resistant Depression.
Electroconvulsive therapy (ECT) has unparalleled efficacy in treating severe depression that is resistant to common modalities of treatment, such as antidepressant medication.
- Trial name
- NCT01748708
- Testing
- Magnetic seizure therapy, Electroconvulsive therapy
- Where
- Canada
- Sponsor
- Centre for Addiction and Mental Health
Bipolar Disorder
Depakote-ER for Depressive and Bipolar Depression
Obtain information using a randomized treatment to assess the antidepressant and anxiolytic efficacy of divalproex vs. placebo for nonrefractory bipolar patients with major depressive episodes.
- Trial name
- NCT00226343
- Testing
- Depakote-ER
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Opioid Use Disorder, Severe, in Sustained Remission, Opioid Use Disorder, Severe, in Early Remission
KAP for Depression in Abstinent Opioid Users
The purpose of the study is to examine whether an investigational medication called ketamine along with psychotherapy is an effective treatment for depression in participants with a history of opioid addiction who have not abused…
- Conditions
- Opioid Use Disorder, Severe, in Sustained Remission, Opioid Use Disorder, Severe, in Early Remission, Major Depressive Disorder
- Trial name
- KReDO (NCT05193318)
- Testing
- Ketamine-assisted psychotherapy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Medical University of South Carolina
Depressive Disorder, Major Depressive Disorder
Study Evaluating Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR) In The Treatment Of Child and Adolescent Outpatients With Major Depressive Disorder
The primary purpose of this study is to evaluate the long-term safety and tolerability of Desvenlafaxine Succinate Sustained-Release (DVS SR) in child and adolescent outpatients with major depressive disorder.
- Trial name
- NCT00669110
- Testing
- Desvenlafaxine Succinate Sustained-Release Tablets (DVS SR)
- Where
- 9 sites in United States
- Volunteers
- 40 people
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Depression / Major Depressive Disorder
Adjunctive Probiotic Therapy in Major Depressive Disorder (ProMOOD)
A double-blind, randomized controlled trial (RCT) aimed at evaluating the efficacy of probiotic supplementation in patients undergoing concurrent antidepressant therapy.
- Trial name
- ProMOOD (NCT07786285)
- Testing
- OMNi-BiOTiC® STRESS Repair
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Maribor
Major Depressive Disorder
Repetitive Transcranial Magnetic Stimulation (rTMS) for Treatment Resistant Depressive Disorder
Major Depressive Disorder (MDD) is one of the most prevalent mental illnesses in North America, in which 30% - 40% fail to respond to conventional treatment.
- Trial name
- NCT01515215
- Testing
- Repetitive Transcranial Magnetic Stimulation
- Where
- Canada
- Volunteers
- 107 people
- Sponsor
- Centre for Addiction and Mental Health
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