Clinical trials: Disorder, Pediatric
Child, Anesthesia Morbidity
A Study on the Effects of Midazolam on Delirium After Sevoflurane Anesthesia in Pediatric Strabismus Surgery
Sevoflurane with its rapid induction and emergence, hemodynamic stability, and nonirritating airway properties, has acquired widespread acceptance in children.
- Conditions
- Child, Anesthesia Morbidity, Delirium on Emergence
- Trial name
- NCT01680471
- Testing
- Midazolam 0.03mg/kg, Midazolam 0.05mg/kg
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Korea University Anam Hospital
CHD - Congenital Heart Disease
Ultrafast Ultrasound Imaging in Pediatric Cardiology
About 13 in 1000 children are born with heart disease. Current tools poorly assess heart filling in children, limiting treatment.
- Trial name
- NCT07255144
- Testing
- Cardiac Ultrafast Ultrasound
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Bordeaux
Developmental Disabilities, Autistic Spectrum Disorder
"Family-centered" Pediatric Rehabilitation Services in Children With Developmental Disabilities
Developmental disability is a severe chronic disabled condition caused by mental or physical impairments. Children with developmental disabilities may face life-long difficulties in motor functioning, self-care, condition…
- Trial name
- NCT02057809
- Where
- Taiwan
- Volunteers
- 130 people
- Sponsor
- Chang Gung University
Central Nervous System Tumor, Pediatric, Leukemia
Etoposide, Cyclophosphamide, Thalidomide, Celecoxib, and Fenofibrate in Relapsed or Progressive Cancer
RATIONALE: Drugs used in chemotherapy, such as etoposide and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing.
- Conditions
- Central Nervous System Tumor, Pediatric, Leukemia, Lymphoma, Neuroblastoma
- Trial name
- NCT00357500
- Testing
- celecoxib, cyclophosphamide, etoposide
- Where
- 10 sites in United States
- Volunteers
- 101 people
- Sponsor
- Dana-Farber Cancer Institute
Sickle Cell Anemia
Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea
The primary goal of the Phase III TWiTCH trial is to compare 24 months of alternative therapy (hydroxyurea) to standard therapy (transfusions) for pediatric subjects with sickle cell anemia and abnormally high (≥200 cm/sec)…
- Trial name
- TWiTCH (NCT01425307)
- Testing
- Hydroxyurea
- Volunteers
- 159 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Glioma, Rhabdomyosarcoma
Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors
This study proposes to treat patients with the combination of erlotinib and temozolomide. Patients with relapsed, recurrent, refractory, or high risk malignancies whose tumors possess a non-synonymous mutation in EGFR, ERBB2, or…
- Conditions
- Glioma, Rhabdomyosarcoma, Osteosarcoma, Medulloblastoma
- Trial name
- NCT02689336
- Testing
- Erlotinib, Temozolomide
- Sponsor
- Washington University School of Medicine
Eye Diseases
Evaluation and Treatment of Pediatric, Developmental, and Genetic Eye Diseases
This study will evaluate and treat children or adults with inherited or developmental eye conditions. It will allow specialists in pediatric ophthalmology, genetic ophthalmology, and ocular motility at the National Eye Institute…
- Trial name
- NCT00076271
- Where
- 2 sites in United States
- Volunteers
- 350 people
- Sponsor
- National Eye Institute (NEI)
Asthma (Diagnosis)
Chronic Effects of Photobiomodulation With an LED Vest on Functional Capacity, Inflammatory Markers, and Muscle Perfusion in Children With Asthma
Asthma is a chronic inflammatory disease of the airways that results in tissue remodeling, airflow limitation, and bronchial hyperresponsiveness.
- Trial name
- Asthma PBM (NCT07613671)
- Testing
- Photobiomodulation, Exercise
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Nove de Julho
Asthma
Study of Daily Dosing With Levalbuterol, Racemic Albuterol, and Placebo in Pediatric Subjects With Asthma
Study of Daily Dosing with Levalbuterol, Racemic Albuterol, and Placebo in Pediatric Subjects with Asthma
- Trial name
- NCT00073814
- Testing
- Levalbuterol tartrate MDI, racemic albuterol MDI
- Where
- 45 sites in United States
- Volunteers
- 80 people
- Sponsor
- Sumitomo Pharma America, Inc.
Obesity, Childhood
Milk Proteins and Micronutrient Supplementation in Obese Children
Milk proteins and micronutrients could be beneficial in the prevention and treatment of obesity. The objective was to evaluate a supplement with milk proteins and multivitamins and minerals with nutrition education on…
- Trial name
- NCT04319419
- Testing
- Supplement with micronutrients, Nutrition education
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Queretaro
Cerebral Palsy (CP)
Non-Immersive Virtual Reality for Gait and Balance Training in Children With Cerebral Palsy
The goal of this clinical trial is to evaluate the feasibility and user satisfaction of a non-immersive VR rehabilitation system, i.e.
- Trial name
- Rehametrics-CP (NCT07612332)
- Testing
- non inmersive VR System
- Where
- Peru
- Volunteers
- 10 people
- Sponsor
- Universidad Nacional de San Agustin de Arequipa
Inadequate or Impaired Breathing Pattern or Ventilation, Difficult Intubation
Difficult Bag Mask Ventilation and Difficult Intubation in Children
Unanticipated difficult airway comprises of unexpected difficult bag mask ventilation or unforeseen difficult laryngoscopy. The incidence of difficult laryngoscopy or unanticipated difficult intubation in children was varied from…
- Conditions
- Inadequate or Impaired Breathing Pattern or Ventilation, Difficult Intubation, Anesthesia; Adverse Effect
- Trial name
- NCT02823392
- Testing
- DBMV
- Where
- Thailand
- Volunteers
- 765 people
- Sponsor
- Prince of Songkla University
Multisystem Inflammatory Syndrome in Children, COVID-19
COVID-19: Immunological Mechanisms in Multisystem Inflammatory Syndrome in Children
This study seeks to explore immunological mechanisms in patients with Multisystem Inflammatory Syndrome in Children (MIS-C) to improve the understanding of this pathogenesis of this disease.
- Conditions
- Multisystem Inflammatory Syndrome in Children, COVID-19, SARS-CoV-2 Infection
- Trial name
- NCT05334134
- Where
- Denmark
- Volunteers
- 300 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Familial Mediterranean Fever
Genotype and Phenotype in Pediatric Familial Mediterranean Fever
This cross-sectional study aims to assess the spectrum of MEFV gene mutations and their relation to clinical manifestations and disease severity in children with Familial Mediterranean Fever attending Assiut University Children…
- Trial name
- NCT07849998
- Volunteers
- 84 people
- Sponsor
- Assiut University
Familial Hypercholesterolaemia
An Study to Evaluate Rosuvastatin in Children and Adolescents With Familial Hypercholesterolaemia
This study is being carried out to see if the study medication, rosuvastatin, is effective in treating familial hypercholesterolaemia in children and adolescents, and to determine the long term (over 2 years) safety, tolerability…
- Trial name
- NCT01078675
- Testing
- rosuvastatin calcium
- Where
- 15 sites in United States, Belgium and 3 more
- Volunteers
- 315 people
- Sponsor
- AstraZeneca
Obsessive-Compulsive Disorder, Tic Disorder
Pathogenesis of Pediatric Obsessive-compulsive Disorder: Based on the Microbiota-gut-brain Axis
This study aims to investigate the characteristics of the microbiota-gut-brain axis in pediatric patients with obsessive-compulsive disorder (OCD) through performing an integrated analysis of gut microbiota, serum metabolomics…
- Trial name
- NCT06754319
- Where
- China
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Inflammatory Bowel Disease, Crohn's Disease
Levels of the Stat4 Alpha and Stat4 Beta Isoforms in PBMCs From Patients With Crohn's Disease and Ulcerative Colitis
The goal in these studies will be to assess the relative levels of the Stat4 alpha and Stat4 beta isoforms in PBMCs from patients with Crohn's Disease, ulcerative colitis, celiac disease or from control patients.
- Conditions
- Inflammatory Bowel Disease, Crohn's Disease, Ulcerative Colitis
- Trial name
- NCT00586599
- Testing
- measurement of inflammatory markers
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Indiana University
Lysosomal Acid Lipase Deficiency
Lysosomal Acid Lipase Deficiency in Risk Groups
A multicenter real-world observational study of the prevalence, diagnostic pathways, and clinical characteristics of lysosomal acid lipase deficiency in pediatric and adolescent risk groups in the Russian Federation (HELIOS)
- Trial name
- HELIOS (NCT07455864)
- Where
- 2 sites in Russia
- Volunteers
- 25 people
- Sponsor
- AstraZeneca
Pediatric Pain and Anxiety
Painful Procedures in the Emergency Department: A Distraction Intervention
This study is designed to assess the effectiveness of the video-based intervention over and above current standard practice for pain control in the pediatric emergency department (ED).
- Trial name
- ERPain (NCT00338364)
- Testing
- PAT
- Where
- Canada
- Volunteers
- 189 people, healthy volunteers welcome
- Sponsor
- IWK Health Centre
Obesity, Pregnancy
Starting Pediatric Obesity Prevention in Pregnancy
The purpose of this study is to examine whether we can use social networks to spread health information and health behaviors during pregnancy to prevent excessive gestational weight gain.
- Trial name
- NCT01279109
- Testing
- Social network building intervention, Home visit
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
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