Clinical trials: Disorder
Hyperthermia, Heat Exposure
Hot Water Immersion as a Heat Acclimation Strategy in Older Adults
Aging is associated with impairments in heat loss responses of skin blood flow and sweating leading to reductions in whole-body heat loss.
- Conditions
- Hyperthermia, Heat Exposure, Heat Stress, Thermoregulation
- Trial name
- NCT05838612
- Testing
- Heat acclimation
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Pediatric Obesity
Developing Novel Methods to Teach Children to Recognize Internal Signals of Hunger
The purpose of this multi-year project is to develop an evidence-based curriculum for teaching preschool children to eat in response to internal hunger and fullness signals.
- Trial name
- CTSI (NCT03064919)
- Testing
- Curriculum Testing
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Penn State University
Virtual Reality, Anxiety
The Effect of Virtual Reality Application on Anxiety and Patient Satisfaction During Intrauterine Insemination (IUI)
This study will conduct as a randomized pretest-posttest study to examine the effect of virtual reality glasses (VRG) application during the IUI procedure on anxiety and patient satisfaction.
- Conditions
- Virtual Reality, Anxiety, Patient Satisfaction, Intrauterine Insemination (IUI)
- Trial name
- (IUI) (NCT06346730)
- Testing
- Virtual reality glasses to intervention group
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Suleyman Demirel University
Acute Cerebral Infarction
Correlation Analysis Between Peripheral Blood PrPC Levels and Disease Severity and Prognosis in Patients With Acute Cerebral Infarction
The primary objective of this observational study is to investigate alterations in PrPc levels in peripheral blood during acute cerebral infarction, as well as the correlation between these changes and both disease severity and…
- Trial name
- NCT07513428
- Where
- China
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- The First Hospital of Jilin University
Obesity, Child
Thiamin Deficiency in Obese Thai Children
This study is aimed to assess the prevalence of thiamin deficiency in obese Thai children.
- Conditions
- Obesity, Child, Thiamine Deficiency
- Trial name
- NCT02464865
- Testing
- Thiamine 1, Non-thiamine, Thiamine 2
- Where
- Thailand
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Healthy Aging, Overweight and Obesity
Multi-Domain Exercise Program In Older Women
The goal of this clinical trial is to learn whether a long-term exercise program can improve physical health and well-being in older women aged 60 years and older who live in the community.
- Conditions
- Healthy Aging, Overweight and Obesity, Physical Fitness, Psychological Well-being
- Trial name
- MD-EX Women (NCT07311265)
- Testing
- Supervised Multidomain Exercise Program
- Where
- Brazil
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Universidade do Oeste de Santa Catarina
Cervical Cancer, Behavior
Adaptation and Implementation of a Patient Navigation Program for Cervical Cancer Screening Across Contexts in Senegal
The goal of this project is to prevent unnecessary deaths due to cervical cancer in Senegal. This mixed methods research responds to identified intrapersonal- and community-level barriers to early cervical cancer screening…
- Trial name
- NCT05544084
- Testing
- Patient Navigator Approach
- Where
- Senegal
- Volunteers
- 901 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Sinusitis
Development and Validation of a NIRS-based Sinusitis Screening
The research at University of California Irvine, Beckman laser institute and Praxis Biosciences Incorporation, develope near-infrared trans-illumination methods.
- Trial name
- NCT01485484
- Testing
- Optic imaging use near-infrared trans-illumination methods
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Spinal Cord Injury, Paraplegia and Tetraplegia
Self-balancing Personal Exoskeleton for SCI (WINY)
This study aims to demonstrate the safety and effectiveness of the personal exoskeleton in individuals with spinal cord injury (SCI).
- Trial name
- NCT07222033
- Testing
- Hands-free exoskeleton
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Wandercraft
T Cell Lymphoma
A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-Cell Lymphoma Patients
This study will be a pilot study of sorafenib 400mg PO twice daily in refractory T-cell lymphomas including peripheral T-cell lymphoma (PTCL), angioimmunoblastic lymphadenopathy (AILD), cutaneous T cell lymphoma (CTCL)…
- Trial name
- NCT01561833
- Testing
- Sorafenib
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Kidney Diseases, Cardiovascular Diseases
Cardiorenal Protective Diet
This study will evaluate providing fruits and vegetables in a sustainable community care clinic setting, in addition to routine medical care, to individuals with CKD (Stage 2-4) on CKD and CVD risk, or cardio-renal risk factors.
- Conditions
- Chronic Kidney Diseases, Cardiovascular Diseases, Hypertension
- Trial name
- CPD (NCT04117204)
- Testing
- Fruits and Vegetables
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Opiate Dependence
ALK21-004: Single-dose Opiate Challenge of Medisorb® Naltrexone (VIVITROL®) in Adults Who Use Opioids
This was a Phase 2, multicenter, randomized, double-blind pilot study in opioid-using adults to assess the presence, duration, and degree of opiate blockade as well as the safety and tolerability of Medisorb® naltrexone…
- Trial name
- NCT01218984
- Testing
- Medisorb naltrexone 75 mg, Medisorb naltrexone 150 mg, Medisorb naltrexone 300 mg
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alkermes, Inc.
Prostate Cancer
DNA Changes in Patients With Prostate Cancer
RATIONALE: Collecting and storing samples of blood from patients and their brothers with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
- Trial name
- NCT00899184
- Testing
- polymorphism analysis, laboratory biomarker analysis
- Volunteers
- 646 people, healthy volunteers welcome
- Sponsor
- ECOG-ACRIN Cancer Research Group
Rheumatoid Arthritis
Study of the Tolerability of Different SAR153191 Drug Products, That Differ With Respect to Manufacturing Processes and Formulation, at Different Concentrations and Doses in Healthy Male Subjects
Primary objective: To determine the tolerability of different SAR153191 drug products that differ with respect to manufacturing processes and formulation, at different concentrations and doses, after administration of single…
- Trial name
- NCT06159452
- Testing
- SAR153191-P3 drug product, SAR153191-P2 drug product, SAR153191-C1F3 drug product
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Sanofi
Human Papillomavirus Infection, Cervical Intraepithelial Neoplasia
Long-Term Immune Persistence After Bivalent HPV Vaccination in Females From Study 311-HPV-1005
This is a single-center, open-label, prospective observational extension of Study 311-HPV-1005 (NCT04965350). The study follows females who received at least one dose of a bivalent human papillomavirus vaccine containing HPV-16…
- Trial name
- NCT07833852
- Testing
- Recombinant Human Papillomavirus Bivalent (Types 16 and 18) Vaccine (Pichia pastoris)
- Where
- China
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- Shanghai Zerun Biotechnology Co.,Ltd
Overweight and Obesity
The Fasting and Shifted Timing (FAST) of Eating Study
The aim of this study is to assess peoples' satisfaction with their diet based on adhering to three different meal-timing protocols for one week each: (1) Time-restricted feeding (TRF); (2) Intermittent fasting (IF); and (3)…
- Trial name
- FAST (NCT04527952)
- Testing
- Online handouts describing how to follow each diet for 1 week each
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Obesity
The Effect of Vitamin A Supplementation on Cytokine Profile in Obesity
In this double blind placebo controlled trial,cytokine secretion of CD4+ T-cells after 4 month supplementation of vitamin A will be compared with placebo intaking group.
- Trial name
- NCT01405352
- Testing
- Vitamin A
- Where
- Iran
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Falciparum Malaria, Antimalarials
The Impact of Artemether-Lumefantrine on Genes Associated With Antimalarial Resistance
The newly introduced antimalarial drug artemether-lumefantrine is currently recommended as second line antimalarial in Sudan. Recurrent infection after treatment with this drug has been associated with selection of certain genes…
- Trial name
- NCT00440752
- Where
- Sudan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tropical Medicine Research Institute
Sickle Cell Disease, Pain
Nitric Oxide and Sickle Cell Pain
Background: Sickle cell disease often causes crises, with episodes of pain. Many people with sickle cell disease also have pain between crises. Inflammation is an important part of sickle cell pain.
- Trial name
- NCT01393847
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Sleep, Alzheimer Disease
Sleep Trial to Prevent Alzheimer's Disease
The purpose of this study is to determine if treatment with the sleep aid suvorexant can decrease the rate of amyloid-β (Aβ) accumulation in the brain.
- Trial name
- SToP-AD (NCT04629547)
- Testing
- Suvorexant 20 mg
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.