Clinical trials: Disorder
Hepatitis B
Safety and Immunogenicity of a Booster Dose of GlaxoSmithKline (GSK) Biologicals' Hepatitis B Vaccine
In this study, subjects who received primary neonatal vaccination with hepatitis B vaccine at 0, 1, 2, 12 months, 20 years ago in the 103860/272 primary study will be evaluated for immunological memory to hepatitis B vaccine via…
- Trial name
- NCT00657657
- Testing
- Engerix™-B
- Where
- Thailand
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Polycystic Ovary Syndrome (PCOS), Metabolic Syndrome
Malay Women With PCOS and Their Association With Metabolic Syndrome
The abnormalities that characterize the Metabolic Syndrome (MetS) confer an increased risk of cardiovascular and other diseases.
- Trial name
- MPMSS (NCT03414957)
- Testing
- Hormonal and biochemical blood tests and ultrasound scanning
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Cyberjaya University College of Medical Sciences
Glaucoma
The Genetic Study of Primary Angle-Closure Glaucoma
The purpose of this study is to evaluate the possible candidate gene of Primary Angle-Closure Glaucoma.
- Trial name
- NCT00155857
- Where
- Taiwan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Psoriasis
Effects of Treatment With Biological Agents on Vascular and Cardiac Function in Psoriasis
Psoriasis has been associated with an increasing risk for atherosclerosis. The investigators investigated whether surrogate markers of subclinical atherosclerosis, vascular dysfunction and myocardial dysfunction are impaired in…
- Trial name
- NCT02144857
- Testing
- etanercept, ustekinumab, cyclosporine
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Athens
Osteoarthritis
Retrospective Follow-up Study of Synvisc® in Patients With Knee Osteoarthritis
Retrospective collection of data, aimed at a better knowledge of the use of Synvisc® among the patients with knee osteoarthritis (OA) since at least three years.
- Trial name
- NCT02195557
- Testing
- Synvisc®
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Presbyopia
Evaluating the Success of Habitual Multifocal Wearers When Refit With a New Lens Design
The objective of the study was to adapt existing multifocal soft lens wearers to a CONTROL lens for 2 weeks and then evaluate the success of switching them to the TEST lens, with a review after 2 weeks.
- Trial name
- NCT04952701
- Testing
- Control lenses, Test lenses
- Where
- 5 sites in United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- CooperVision, Inc.
Infertility
Prospective, Randomized Trial Comparing ICSI to Insemination for Non-Male Factor Patients Undergoing PGT-A
Intracytoplasmic sperm injection (ICSI) is a procedure performed during in vitro fertilization (IVF) in which a single sperm is injected directly into an oocyte.
- Trial name
- NCT05548101
- Testing
- ICSI
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Texas Fertility Center
Healthy Volunteer, Skin Condition
CaroRite™ for Skin Health and Signs of Ageing
The goal of this study is to investigate the efficacy of carotenoids administered orally on skin health, skin condition and visible signs of ageing in healthy females aged 40-55 years old.
- Conditions
- Healthy Volunteer, Skin Condition, Ageing Signs
- Trial name
- NCT06878001
- Testing
- Carotenoids
- Where
- Australia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Probiotics Infant Formula, Infants Health
The Impact of Infant Formula With Probiotics on Infants Health
The trial will be divided into three groups, the experimental group: (I) probiotic A formula, (II) probiotic B formula; control group: (III) regular formula (Youluck infant formula).
- Trial name
- NCT03993301
- Testing
- Probiotic A formula, Probiotic B formula, Regular formula
- Where
- Taiwan
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Primary Progressive Aphasia, Repetitive Transcranical Magnetic Stimulation
rTMS Treatment of Primary Progressive Aphasia
Primary Progressive Aphasia (PPA) is a neurodegenerative disease in which language function is gradually and progressively impaired.
- Trial name
- NCT04431401
- Testing
- Magstim rTMS
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Autism Spectrum Disorder With Intellectual Deficiency
Recording Stress Biomarkers in Autism Spectrum Disorders
The goal of this observational study is to learn how stress affects children and young people with autism spectrum disorder (ASD).
- Trial name
- STRESSDEFIS (NCT07535801)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universite Cote d'Azur
Cerebrovascular Disorders, Cognition Disorders
Renji Cerebral Small Vessel Disease Corhort Study
We aim to make clear the impact with the mechanisms of variant pathological injuries on the outcomes of CSVD, to find independent imaging markers and establish prediction model of it.
- Trial name
- RCCS (NCT03544801)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- RenJi Hospital
Malocclusion
Effect of AcceleDent® Aura on Orthodontic Tooth Movement With Aligners
The purpose of this study is to examine the amount of tooth movement achieved over time between subjects undergoing aligner treatment using a pulsation device known as AcceleDent® Aura with those not using the device.
- Trial name
- NCT01962012
- Testing
- AcceleDent Aura
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- OrthoAccel Technologies Inc.
Obesity
The Impact of an Investment Based Intervention on Weight-loss and Beliefs About Food in Patients Post Bariatric Surgery
Although obesity surgery is currently the most effective method for achieving weight loss, not all patients lose the desired amount of weight and some show weight regain.
- Trial name
- NCT02045628
- Testing
- Investment intervention
- Where
- United Kingdom
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- University of Surrey
Cognitive Impairment, Mild, Cognitive Dysfunction
MCLENA-2: A Phase II Clinical Trial for the Assessment of Lenalidomide in Patients With Mild Cognitive Impairment
This is a randomized, double-blind, placebo-controlled, parallel group study. The use of placebo is appropriate to minimize bias related to treatment expectations of the subject, study partner, and site investigator, as well as…
- Conditions
- Cognitive Impairment, Mild, Cognitive Dysfunction, Amyloid Plaque, Neurodegenerative Disease, Hereditary
- Trial name
- NCT06177028
- Testing
- Lenalidomide 10 mg
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
Leber Congenital Amaurosis (LCA)
Psychotherapy Group for Parents of Children With LCA
The objectives of this study are to evaluate the effect of a group psychotherapy intervention for parents of children/adolescents with LCA on indicators of emotional health, parental stress, acceptance, cognitive defusion, and…
- Trial name
- NCT07026565
- Testing
- Psychotherapy group for parents, Control Group
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Instituto de Genética Ocular
Vaginosis, Bacterial
Use of Blue Light Emitting Diode in the Treatment of Women With Bacterial Vaginosis: a Clinical Trial
Bacterial Vaginosis (BV) is a infectious process of the female genitourinary tract, an important health issue due to the high incidence and high rate of recurrence of the infection.
- Trial name
- NCT03500107
- Testing
- Blue Light Emitting Diode (LED) 401 +/- 5nm
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Sleep Disorder
Effects of an Osteopathic Treatment Protocol on Sleep Quality
SIngle-centre interventional single-blinded randomized controlled trial, with random assignment of the subjects in two groups (intervention and control, 1: 1 ratio) and to be carried out with volunteers that present alterations…
- Trial name
- NCT04955392
- Testing
- Osteopathic treatment protocol
- Where
- Spain
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Ramón Mateos Alpuente
Obstructive Sleep Apnea, Metabolic Syndrome X
Obstructive Sleep Apnea (OSA) and Metabolic Syndrome: Role of Oxidative Stress
The purpose of this study is to define the mechanism(s) through which Obstructive Sleep Apnea/Hypopnea (OSAH) promotes abnormal metabolic processes which characterize the metabolic syndrome.
- Trial name
- NCT00177892
- Testing
- sleep disruption, sleep with and without positive pressure
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
Psoriasis
The Association Between Psoriasis and Intestinal Bacterial Population
At least 20 psoriasis patients will be compared to at least 20 participants without psoriasis Bacterial genomic DNA will be extracted from stool samples of participants.
- Trial name
- PIB (NCT02417792)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Assuta Hospital Systems
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