Clinical trials: Disorder
Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma
Near Infrared Technology and Laparoscopic Resection of Pancreatic Lesions: the COLPAN Project
The purpose of this study is to determine whether the use of Near-Infrared Technology can guide the laparoscopic resection of hypervascular neoplasms of the pancreas.
- Conditions
- Pancreatic Neuroendocrine Tumors, Clear Cell Renal Carcinoma, Solid Pseudopapillary Tumors of the Pancreas
- Trial name
- NCT02685553
- Testing
- NIR
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Malnutrition, Intestinal Diseases, Parasitic
The Effect of a Deworming Intervention to Improve Early Childhood Growth and Development in Resource-poor Areas
Worldwide, over 2 billion people suffer from worm infections in developing countries. These infections are especially damaging to the health of children, resulting in both short-term and lifelong disability.
- Trial name
- NCT01314937
- Testing
- Mebendazole, Usual care
- Where
- Peru
- Volunteers
- 1,760 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Pulp Necrosis, Periapical Lesion
Success Rate of Single Versus Two Visit Regenerative Treatment Protocol in Non Vital Mature Anterior Teeth
This study evaluates success rate of non vital mature anterior teeth with periapical lesion treated by regenerative endodontic protocol in single visit versus two visit technique.
- Conditions
- Pulp Necrosis, Periapical Lesion, Anterior Teeth
- Trial name
- NCT03717337
- Testing
- Single visit pulp regeneration, Two visit pulp regeneration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Appointments and Schedules, Outpatient Clinics, Hospital/Economics
Non Attendance at Scheduled Appointments as a Marker of Mortality and Hospital Admission
To evaluate the association of non attendance at scheduled appointments with visits in the emergency department, hospitalizations and mortality during one year follow up.
- Conditions
- Appointments and Schedules, Outpatient Clinics, Hospital/Economics, Emergency Department, Hospitalization
- Trial name
- NCT02210637
- Where
- Argentina
- Volunteers
- 177,083 people, healthy volunteers welcome
- Sponsor
- Hospital Italiano de Buenos Aires
HIV Infections
Safety and Pharmacokinetics of Dapivirine/Maraviroc Vaginal Ring
The purpose of this study is to assess the pharmacokinetics of the combination dapivirine and maraviroc vaginal ring and determine whether it is safe when used continuously for 28 days by healthy women in the United States.
- Trial name
- NCT01363037
- Testing
- Dapivirine Vaginal Ring, Maraviroc Vaginal Ring, Dapivirine-Maraviroc Vaginal Ring
- Where
- 3 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- International Partnership for Microbicides, Inc.
Stroke
Development of a Tailored Life-Sustaining Treatment Decision Support Intervention for Stroke Surrogate Decision Makers
The trial is testing an investigator-developed decision support tool for surrogate decision makers for stroke patients that are unable to make medical decisions for themselves.
- Trial name
- NCT03427645
- Testing
- Decision tool
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Pregnancy Complications, Pregnancy Related
PRECISE - Objective Measures and Observations of Physical Exposures Among Pregnant Employees in the Danish Workforce
Occupational physical activity during pregnancy may decrease blood supply to the uterus and be connected to negative pregnancy outcomes.
- Conditions
- Pregnancy Complications, Pregnancy Related, Preterm Birth, Small for Gestational Age at Delivery
- Trial name
- PRECISE (NCT05670145)
- Testing
- PRECISE
- Where
- Denmark
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Major Depressive Disorder, Post-Traumatic Stress Disorder
Examination of Glutamate and mGluR5 in Psychiatric Disorders
This research study is designed to look at the involvement of the glutamate system in depression. Each subject will undergo a screening appointment to determine study eligibility.
- Conditions
- Major Depressive Disorder, Post-Traumatic Stress Disorder, Bipolar Disorder
- Trial name
- NCT02727972
- Testing
- Cognitive Testing, MRI, PET
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Yale University
Laryngopharyngeal Reflux
The Effects of Dexlansoprazole for the Treatment of Throat-Related Reflux
Recent studies have demonstrated that patients with throat-related reflux often require twice daily proton pump inhibitor therapy to attain significant symptomatic improvement, with once daily therapy offering little relief.
- Trial name
- NCT01317472
- Testing
- dexlansoprazole
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hepatitis B
Development of Read-outs in Healthy, Hepatitis B Virus Naive Adults Vaccinated With the Hepatitis B Surface Antigen (HBsAg) in Combination With a GlaxoSmithKline (GSK) Biologicals' Adjuvant System
This study aims to develop innovative immunological read-outs and new technologies in order to further characterise the early immune response and its kinetics as well as the adaptive immune responses to adjuvanted vaccines.
- Trial name
- NCT01777295
- Testing
- Adjuvanted Hepatitis B surface antigen (HBsAg) candidate vaccine GSK2231392A., EngerixTM-B
- Where
- Belgium
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Sciatica
Pain Relief by Platelet-rich Plasma (PRP) Treatment
Past PRP therapy is not sufficient for some part of patients.In this clinical research, The integrated application of PRP with extracellurar matrix and some type of stem cell technique.
- Trial name
- NCT01749839
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Saint Bernard Mission University
Hepatitis B
Persistence of Immunity Against Hepatitis B in 12-13 Year Old Adolescents After Infant Hepatitis B Vaccination
This phase IV open study will evaluate the persistence of humoral antibodies against hepatitis B as well as the immune response to a challenge dose of hepatitis B vaccine in adolescents aged 12-13 years, who received three…
- Trial name
- NCT00984139
- Testing
- Engerix™-B Kinder
- Where
- 24 sites in Germany
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Huntington's Disease
Child to Adult Neurodevelopment in Gene Expanded Huntington's Disease
Huntington's Disease (HD) is an autosomal dominant disease manifested in a triad of cognitive, psychiatric, and motor signs and symptoms. HD is caused by a triplet repeat (CAG)expansion in the gene Huntingtin (HTT).
- Trial name
- ChANGE HD (NCT01860339)
- Where
- 6 sites in United States
- Volunteers
- 488 people, healthy volunteers welcome
- Sponsor
- Peggy C Nopoulos
Prader-Willi Syndrome
Stress and Brain Response Using MEG in PWS
Individuals with Prader-Willi Syndrome (PWS) have increased hunger and food seeking behaviour, as well as learning (cognitive) challenges.
- Trial name
- NCT04032639
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Cardiac Arrest
Pediatric Intubation During CPR
We hypothesized that the video-laryngoscopes are beneficial for intubation of pediatric manikins while performing CPR. In the current study, we compared effectiveness of two video-laryngoscopes (the Coopdech video Laryngoscope…
- Trial name
- ETICPR (NCT02289677)
- Testing
- ATMOS Scope, COOPDECH, AirTraq
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Hypertension, Cardiovascular Risk
Evaluation of the Clinical Benefit of the Aktiia Blood Pressure Monitoring for Early Awareness of Hypertension and Prediction of Cardiovascular Risk
Because Aktiia S.A. has been the first-ever company to put in the market an Optical Blood Pressure Monitoring device, there is a need for Aktiia S.A.
- Conditions
- Hypertension, Cardiovascular Risk, Blood Pressure Check (Hypertension Screening)
- Trial name
- FORESEE2024 (NCT06670677)
- Testing
- Lifestyle survey completion, Unlimited on-demand blood pressure measurements with G2C, Continual blood pressure measurements with G1
- Where
- 2 sites in Switzerland, United Kingdom
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- Aktiia SA
Peanut Allergy
The Safety and Efficacy of a Peanut Immunotherapy Dissolving Film for Peanut Allergy
The purpose of this study is to determine if a new method of administration of peanut sublingual immunotherapy, a dissolving peanut film, is effective.
- Trial name
- NCT01897077
- Testing
- Peanut Dissolving Film
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Multiple System Atrophy - Cerebellar Subtype (MSA-C), Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
Targeted Α-synuclein PET Imaging in the Diagnosis of Multiple System Atrophy
The aim of this study was to apply the targeted α-synuclein PET study technique to investigate the pathological load and spatial distribution characteristics of α-syn in MSA patients, and to assess its value as a biomarker for…
- Trial name
- NCT06890377
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Min Zhao,MD
Obstructive Sleep Apnea
Vasoactive Hormones and Oxygen Saturation During Apneic Events in Patients With Obstructive Sleep Apnea
The mechanisms involved in development and maintenance of hypertension in obstructive sleep apnea are not clarified. We hypothesize that patients with obstructive sleep apnea have an abnormal level of some vasoactive hormones…
- Trial name
- NCT00438412
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Regional Hospital Holstebro
Asymptomatic State
Effect of Massage Therapy in Cortisol Level
This study evaluates the effect of a single session of Massage Therapy in salivary cortisol level. All participants were assessed on three conditions: Massage session, rest in supine position listening music, and under normal…
- Trial name
- MTCL (NCT02440412)
- Testing
- Massage Therapy, Rest in supine
- Where
- Chile
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Chile
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