Clinical trials: Disorder
Prostatic Neoplasms, Metastases
68Ga-PSMA PET in the Prostate Cancer
Efficacy of 68Ga PSMA PET / CT in the diagnosis of lymph node metastasis in patients with prostate cancer: a single center prospective randomized controlled trial.
- Conditions
- Prostatic Neoplasms, Metastases, PSMA-PET
- Trial name
- NCT04967001
- Testing
- PSMA PET
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
HIV Infections
A Clinical Trial to Evaluate the Safety and Immunogenicity of Recombinant HIV-1 Envelope Protein BG505 SOSIP.GT1.1 Gp140 Vaccine, Adjuvanted in Healthy, HIV-uninfected Adults
This is a phase 1 clinical trial to evaluate the safety, tolerability, and immunogenicity of HIV-1 envelope protein BG505 SOSIP.GT1.1 gp140 trimer Vaccine, Adjuvanted, in up to 48 healthy HIV-uninfected adult volunteers.
- Trial name
- NCT04224701
- Testing
- BG505 SOSIP GT1.1 gp140 Vaccine, Adjuvanted
- Where
- 3 sites in United States, Netherlands
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- International AIDS Vaccine Initiative
Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease
Clinical Decision-Making and Virtual Reality Exercise
Degenerative lumbar spine disease (DLSD) is common in elderly individuals and can result in pain, muscle weakness, and paresthesia.
- Conditions
- Degenerative Lumbar Spinal Stenosis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
- Trial name
- NCT05375201
- Testing
- VR skateboarding training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Renal Impairment, Gout
Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients
Our findings are expected to provide real-world evidence of the renal-adverse effects of colchicine and NSAIDs combination therapy in patients with gout, which will guide healthcare professions in optimizing gout treatment…
- Conditions
- Renal Impairment, Gout, Colchicine Adverse Reaction, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT05006001
- Testing
- Colchicine and NSAID
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- En Chu Kong Hospital
COVID-19, SARS-CoV-2 Infection
A Study to Evaluate the Immunogenicity and Safety of A Recombinant Protein COVID-19 Vaccine as Booster Vaccines
This study is a phase Ⅱ clinical trial to evaluate the safety and immunogenicity of SCTV01E-2 in people of different ages who had been vaccinated with COVID-19 vaccines.
- Trial name
- NCT05933512
- Testing
- SCTV01E-2, SCTV01E
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sinocelltech Ltd.
Essential Tremor
Ventrointermediate Nucleus (VIM DBS) and Working Memory
This is part of a larger study for which participants have already completed memory and thinking tests. In this study, investigators are trying to learn how deep-brain stimulation affects memory skills in essential tremor (ET)…
- Trial name
- WMVIM (NCT00906412)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
MDD, Bipolar Disorder
Evaluation of Generalization Paradigm Patterns Among Different Psychiatric Disorders
Learning includes the ability to generalize to new situations and respond to similar, yet not identical stimuli. In previous work, focused on stimulus generalization in healthy volunteers, tones that were negatively reinforced…
- Conditions
- MDD, Bipolar Disorder, Schizophrenia Disorder, Anxiety Disorder (Panic Disorder or GAD)
- Trial name
- NCT01501812
- Testing
- Generalization pattern
- Where
- Israel
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Mental Health Disorder
Overview of the Mental Health of Adolescents in Therapeutci, Educational and Pedagogical Facilities in France
Assess the prevalence of various psychiatric disorders in adolescents aged 12 to 16 receiving support from therapeutic, educational and pedagogical institutes.
- Trial name
- PsyPreDi (NCT06489912)
- Testing
- WAIS IV
- Where
- 2 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University Hospital, Rouen
Cigarette Smoker, Tobacco Use Disorder
Varenicline and Combined NRT for Smoking Cessation
This randomized pilot phase IV trial studies the side effects and how well varenicline works compared to nicotine replacement therapy in helping patients that smoke to quit.
- Trial name
- NCT02271919
- Testing
- Nicotine Lozenge, Nicotine Patch, Tobacco Cessation Counseling
- Where
- United States
- Volunteers
- 631 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Growth Hormone Deficiency
Growth Hormone's Effect on the Cardiovascular System
To evaluate specific markers of cardiovascular risk before and after growth hormone replacement therapy in a population of growth hormone deficient adults, as compared to an age, gender, and BMI-matched healthy population.
- Trial name
- NCT00397319
- Testing
- Growth Hormone
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Cystic Fibrosis, Healthy Subjects
Evaluation of Nebulization and Positive Expiratory Pressure Combination
The purpose of this study is to compare the efficiency of nebulization and positive expiratory pressure combination
- Trial name
- NCT02535130
- Testing
- Positive expiratory pressure, amikacine nebulization
- Where
- Belgium
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
HIV
Application of IV 99mTc-tilmanocept for Imaging of Macrophage-specific Inflammation
The purpose of this study is to evaluate uptake of intravenously administered 99mTc-tilmanocept using single photon emission computed tomography (SPECT/CT) scanning in individuals with HIV and individuals without HIV.
- Trial name
- NCT03523130
- Testing
- Imaging
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
COVID-19
The Effects of Long-Term Mask Use in the Pandemic Period
Various restrictions have been made all over the world due to coronavirus pandemics. In addition to situations such as social isolation and hygiene, the use of masks is among these rules.
- Trial name
- NCT05358665
- Testing
- mask use
- Where
- Turkey (Türkiye)
- Volunteers
- 909 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
ADHD - Attention Deficit Disorder With Hyperactivity
Sustained Endogenous Attention Deficits in Attention Deficit Hyperactivity Disorder
Subjects with ADHD may exhibit deficits in sustained internal attention. The "Sustained-Paced Finger Tapping" test was recently developed and experimentally used in international literature to assess sustained internal attention…
- Trial name
- NCT06900400
- Testing
- Sustained-Paced Finger Tapping" (Petilli et al., 2018)
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Parkinson Disease, Autonomic Dysfunction
Parkinson's Autonomic Responses to Treadmill Walking
This study will compare examine autonomic and cardiovascular responses to peak exercise testing in Parkinson's disease patients in varying stages of the disease, and healthy, age-matched participants.
- Trial name
- NCT03156400
- Testing
- Exercise Stress Test
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Miami
Obesity, Leptin Deficiency
Effect of Triticum Aestivum on Appetite, Ghrelin, Leptin, Adiponectin Hormonal Axis in Patients With Obesity
Obesity represents one of the major health problems worldwide; it is clear that current approaches to address obesity are largely unsuccessful.
- Conditions
- Obesity, Leptin Deficiency, Ghrelin, Adiponectin
- Trial name
- NCT06496100
- Testing
- Triticum Aestivum
- Where
- Mexico
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Edentulous Jaw
Comparison of Full-arch Implant-supported Frameworks From an Intraoral Scanning or From a Conventional Impression
Purpose: To determine if adjustment of full-arch zirconia frameworks processed on a model obtained with an intraoral scanner and an auxiliary device is not inferior to that of identical frameworks obtained from an elastomeric…
- Trial name
- NCT03992300
- Testing
- Clinical adjustment
- Where
- Spain
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Periodontal Diseases, Pregnancy
The 4th Month Oral Consultation at Pregnant Women
Epidemiological studies have suggested that maternal periodontitis affects the fetal-placental unit, with an increased risk of adverse pregnancy outcome.
- Trial name
- C4M (NCT03132207)
- Testing
- Non interventionel study
- Where
- 2 sites in France
- Volunteers
- 622 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Diabetes, Diabetes Mellitus
Leveraging Community-clinical Linkages to Address Unmet Social Needs for People With Diabetes
This study is a hybrid type 2 design to evaluate the effectiveness and implementation of a community-clinical linkage intervention in primary clinics to address unmet social needs for patients with diabetes living in rural…
- Trial name
- NCT07196007
- Testing
- Community-Clinical Intervention
- Where
- United States
- Volunteers
- 12,000 people, healthy volunteers welcome
- Sponsor
- Mary Lacy
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