Clinical trials: Disorder
Microbial Colonization
Shaping Microbiome in the First 1,000 Days of Life
Events occurring in the early stages of life play an important role in the development of chronic diseases; diet and lifestyle during pregnancy are recognized to be crucial determinants in modulating offspring microbiota…
- Trial name
- AMAMI (NCT04122612)
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Heart Failure
A Study Of The Usage Of Statins In A Community Heart Failure Population
Inflammation and fibrosis may be important contributors to worsening heart failure. As well as lowering cholesterol, statins are also known to reduce inflammatory markers such as C-reactive protein which are elevated in severe…
- Trial name
- NCT00795912
- Testing
- Atorvastatin
- Where
- Ireland
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- St Vincent's University Hospital, Ireland
Anovulation, FHA
FHA: Characterization of Metabolic Status, Brain Circuitry, and Stress-Reactivity
Functional Hypothalamic Amenorrhea (FHA), the spontaneous cessation of the menstrual cycle for at least 6 months after menstrual cyclicity has been established, is a common and reversible form of anovulation not due to…
- Conditions
- Anovulation, FHA, Eumenorrhea, Polycystic Ovary Syndrome
- Trial name
- NCT00453219
- Testing
- Screening evaluation, Meal Response, Blood Collection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Chronic Obstructive Pulmonary Disease
Airway Clearance Study
The purpose of the study is to evaluate how the airways in COPD patients, compared to healthy volunteers, absorb steroid drugs from Symbicort Turbuhaler and Seretide Diskus.
- Trial name
- NCT00379028
- Testing
- Budesonide/Formoterol Turbuhaler, Salmeterol/Fluticasone Diskus
- Where
- 2 sites in Sweden, United Kingdom
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Infertility
SprmPik AI Sperm Selection Study SiD, an Assistant for Sperm Selection During Intracytoplasmic Sperm Injection in Medically Assisted Reproduction: Effect on Fertilization, Blastocyst Formation, Early Pregnancy Loss, and Consistent Practice. A Prospective Pilot Study.
SprmPik AI Assisted Sperm Selection Study SiD, an assistant for sperm selection during intracytoplasmic sperm injection in medically assisted reproduction: effect on fertilization, blastocyst formation, early pregnancy loss, and…
- Trial name
- SprmPik (NCT06518928)
- Testing
- Artificial Intelligence assisted sperm selection
- Where
- 2 sites in United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Insulin Resistance, Chronic Heart Failure
The Role of Insulin Resistance in Patients With Heart Failure and Type 2 Diabetes
The purpose of this cross-sectional comparative 2x2 trial study is to compare the degree of insulin resistance, myocardial function and selected metabolic parameters and to explore the pathophysiological mechanisms by which…
- Trial name
- CARMET2 (NCT02559128)
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Metabolic Syndrome, Obesity Associated Disorder
Dedicated Breast CT for Quantitative Breast Density Measurements in Mexican-origin Women in Southern Arizona
The overall objective of this clinical study is to determine the feasibility of breast CT for breast density assessment and association of CT-derived density measures with metabolic syndrome in overweight/obese Mexican-origin…
- Trial name
- NCT04799665
- Testing
- Breast CT
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Bone Loss
Marginal Bone Loss in Single Implant Restaurations With Different Methods
The investigator is going to measure the marginal bone loss in single implant restaurations with three different methods: direct overcast, milled cad/cam direct to implant restauration and milled cad/cam implant restauration…
- Trial name
- NCT05301400
- Testing
- Bti Unit
- Where
- Spain
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Universidad de León
Parkinson's Disease, Alzheimer's Disease
Biomarkers in Neural Disorders
This study seeks to establish the sensitivity and specificity of what appears to be a unique brainstem biomarker of Parkinson's Disease (PD) - an electrically induced olygosynaptic nasotrigeminal reflex response - in…
- Conditions
- Parkinson's Disease, Alzheimer's Disease, Progressive Supranuclear Palsy, Essential Tremor
- Trial name
- NCT02761707
- Testing
- Electrical Brainstem Responses, Olfactory Tests, Visual Deprivation
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Breast Carcinoma, Cervical Carcinoma
The Ohio State University (OSU) SCREEN Community Program
This clinical trial develops and tests how well a multi-level intervention (MLI), The Ohio State University (OSU) SCREEN Community Program, works to increase screening and follow-up for breast, cervical and colorectal (CRC)…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma
- Trial name
- NCT06666192
- Testing
- Cancer Screening, Discussion, Educational Activity
- Where
- United States
- Volunteers
- 2,067 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Erectile Dysfunction
Stress Management Using an App to Improve Response With PDE5 Inhibitors in Men With Erectile Dysfunction.
The aim of this study is to determine if patients with ED taking PDE5 inhibitors (e.g. Viagra, CIalis, Levitra, Stendra) and experiencing performance anxiety will benefit using a user-friendly stress reducing phone app, Serenita.
- Trial name
- NCT02757807
- Testing
- Utilization of Serenita for Relaxation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Eco Fusion
Stroke
Capsaicin for Cerebral Perfusion Augmentation.
To determine the safety and effect of crescent doses of capsaicin upon serial transcranial Doppler (TCD) markers of cerebral blood flow (CBF).
- Trial name
- NCT04545892
- Testing
- Capsaicin
- Where
- Mexico
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Juan Manuel Marquez Romero
Muscle Tone, Muscle Strength
Pure Impact Treatment to Strengthen and Tone Abdomen, Quadriceps and Glutes Muscles
Open-label, non-randomized, prospective, single-center, self-controlled clinical study.
- Trial name
- NCT07094971
- Testing
- Pure Impact
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Aging, Aphasia
Exercise Effects on Word Learning
The aging Veteran population will substantially increase over the next 10 years, as the 24.9% of Veterans who are currently between 55-64 years of age join the 38.5% who are already over age 65.
- Trial name
- NCT03370471
- Testing
- Retrieval Practice + Moderate Intensity Exercise, Retrieval Practice + Gentle Stretching, Study Only + Moderate Intensity Exercise
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Obese, Weight, Body
Evaluation of the Colonization Capacity of a Probiotic Bacterium.
The goal of this interventional study is to test the colonization of a new generation probiotic in normal weight and overweight/obese people.
- Trial name
- BIOPRED (NCT05878444)
- Testing
- Probiotic
- Where
- Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Valencian Innovation Agency
Hepatitis B, Hepatitis A
Long-Term Immune Persistence of GSK Biologicals' Combined Hepatitis A & B Vaccine Injected According to a 0,6 Month Schedule
The aim of this study is to evaluate the long-term persistence of hepatitis A and B antibodies at Years 6, 7, 8, 9 and 10 after subjects received their first two doses primary vaccination schedule of combined hepatitis…
- Trial name
- NCT00289744
- Testing
- TWINRIX™ ADULT, Engerix TM
- Where
- Belgium
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Postpartum Hemorrhage
Postpartum Oxytocin Administration in the Era of Delayed Cord Clamping
Increased blood loss after vaginal or cesarean delivery is one of the top causes of maternal complications. Oxytocin is a common medication given to mothers by IV or an injection to limit the amount of blood loss after delivery.
- Trial name
- PROCEEDING (NCT04632264)
- Testing
- Initiation of standard postpartum oxytocin immediately following fetal shoulder delivery, Initiation of standard postpartum oxytocin immediately following placenta delivery
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Columbia University
Premature Infant
Urine Biomarkers for Renal Function Monitoring in Preterm Infants
The true renal function of preterm infants is difficult to evaluate. Serum creatinine (Cr) levels in infants are unreliable as a detector of renal function in the first few days of life because they may continue to reflect…
- Trial name
- NCT02813109
- Where
- 2 sites in South Korea
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Inha University Hospital
Dentin Hypersensitivity
A Study Evaluating Oral-Health-Related Quality of Life and Treatment Patterns Among Dentin Hypersensitivity Sufferers
The primary purpose of this study is to characterize changes in Oral-Health-Related Quality of Life (OHrQoL), as measured by the Dentin Hypersensitivity Experience Questionnaire (DHEQ) over a 12-month period.
- Trial name
- NCT07337109
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- HALEON
Healthy Volunteers
Effects of Basic Body Awareness Therapy on Pain, Work Stress, Quality of Life, and Eating Attitudes in Adults
This study will examine the effects of a 10-week Basic Body Awareness Therapy (BBAT) program on pain, work-related stress, quality of life, and eating attitudes in healthy adults working at a university.
- Trial name
- TBFT-WELL (NCT07736599)
- Testing
- Basic Body Awareness Therapy (BBAT)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hitit University
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