Clinical trials: Disorder Characterized by Fever
Acute Febrile Illness, Pneumococcal Infections
Immunogenicity and Safety PCV-20 of the Vaccine Administered During an Acute Febrile Illness in Adults
Streptococcus pneumoniae is responsible for serious infections associated to numerous hospitalizations and high rate of mortality.
- Trial name
- PREV-HOSPIT (NCT06822907)
- Testing
- Early intervention, Delayed intervention
- Where
- 24 sites in France
- Volunteers
- 1,052 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Febrile Illness Acute, Biomarkers
Clinical Aspects, Management and Surveillance of Febrile Illnesses in DRC
The epidemiology and outcome of febrile illnesses in the Democratic Republic of Congo (DRC) is poorly documented. The FIKI² study, a prospective observational study of community-acquired febrile illnesses coordinated by ITM and…
- Conditions
- Febrile Illness Acute, Biomarkers, Surveillance
- Trial name
- FI-CARE (NCT07345286)
- Where
- Democratic Republic of the Congo
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Mothers
The Effect of Salutogenic Model-Based Care on Mothers of Children Suffering From Febrile Illness
This study was designed as an experimental study with pre-test-post-test comparisons and control groups, in order to investigate the effects of salutogenic model-based care on the individual integrity and coping attitudes of…
- Trial name
- NCT07265401
- Testing
- Salutogenic Care Model Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Febrile Illness Acute, Seizures, Febrile
Respiratory Physiology in Children With Febrile Seizures.
Febrile seizures occur in 2-5% of the population and are typically limited to children between 3 months and 5 years-of-age. The pathophysiological link between increased body temperature and increased seizure susceptibility is…
- Trial name
- NCT01906619
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Charite University, Berlin, Germany
Fever, Orthostatic Hypotension
Orthostatic Hypotension in Children With Acute Febrile Illness
Objective:to determent if children suffering from acute febrile illness has higher rate of orthostatic hypotension compared with children with no febrile illness. Design: a prospective cohort study.
- Trial name
- NCT00452712
- Testing
- All subjects will have their blood pressure measured in supine position (after 5 minute of rest) and after 3 minute of standing.
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
Otitis Media, Febrile Illness
Using Pneumococcal Vaccines in Combination for Maximum Protection From Ear and Lung Infections in First 3 Years of Life
HYPOTHESES: 1. That infants receiving PHiD-CV10 as a booster at 12 months of age, compared to controls having no PHiD-CV10 booster (i.e.
- Conditions
- Otitis Media, Febrile Illness, Cough, Lower Respiratory Tract Infection
- Trial name
- PREV-IX_B (NCT01735084)
- Testing
- Prevenar13, Synflorix
- Where
- Australia
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- Menzies School of Health Research
Dengue Fever, Fever
Study of Febrile Illness for Dengue-Endemic Areas in Latin America
The purpose of this study is to detect acute febrile episodes and dengue infection in five Latin American countries to assess dengue seroprevalence.
- Trial name
- NCT01293331
- Where
- 18 sites in Brazil, Colombia and 2 more
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Sanofi
Healthy, Febrile Illness
Prospective Study to Validate the Clinical Accuracy of Norbert Device to Measure Body Temperature
The study will evaluate the clinical bias and clinical repeatability of measuring body temperature using the Norbert Device (ND).
- Trial name
- NCT05640310
- Testing
- Norbert Device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Norbert Health
Cardiovascular Diseases, Respiratory Disease
The Measurement of Vital Signs in Children by Lifelight® Software in Comparison to the Standard of Care
A prospective basic science study for collection of training and testing data for development of Lifelight® Junior
- Conditions
- Cardiovascular Diseases, Respiratory Disease, Febrile Illness, Pediatric ALL
- Trial name
- VISION-Jr (NCT05850013)
- Testing
- Lifelight Junior
- Where
- United Kingdom
- Volunteers
- 504 people
- Sponsor
- Xim Limited
Malaria, Febrile Illness
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: TESTsmART Aim 2 - Nigeria
Highly subsidized first-line antimalarials (artemisinin combination therapy or ACT) are available over the counter in the private retail sector in most malaria-endemic countries.
- Trial name
- NCT04428385
- Testing
- Testing incentive, Conditional artemisinin combination therapy subsidy
- Where
- Nigeria
- Volunteers
- 2,205 people
- Sponsor
- Duke University
Malaria, Febrile Illness
A Randomised Trial of Rapid Diagnostic Tests in the Diagnosis of Malaria in Tanzania
There is clear evidence diagnosis of malaria in much of Africa is sub-optimal and this has a negative impact on patient care. Many of those treated for malaria do not have it.
- Trial name
- NCT00146796
- Testing
- Rapid diagnostic test for malaria
- Where
- Tanzania
- Volunteers
- 2,400 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Febrile Illness Acute, Meningitis, Bacterial
Febrile Infants Swedish Study
Approximately one million febrile infants aged ≤60 days present annually to pediatric emergency departments (PEDs) in Europe and the United States.
- Conditions
- Febrile Illness Acute, Meningitis, Bacterial, Urinary Tract Infection (Diagnosis), Invasive Bacterial Infection
- Trial name
- FISS (NCT07134751)
- Where
- 11 sites in Sweden
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Pseudomyxoma Peritonei, Colorectal Carcinoma
Peritoneal Surface Malignancies - Characterization, Models and Treatment Strategies
The aim of this study is to identify biomarkers of disease recurrence and prognosis to optimize patient selection for treatment with cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC), and through…
- Conditions
- Pseudomyxoma Peritonei, Colorectal Carcinoma, Ovarian Carcinoma, Mesothelioma
- Trial name
- PSM (NCT02073500)
- Testing
- Observational study.
- Where
- Norway
- Volunteers
- 300 people
- Sponsor
- Oslo University Hospital
Acute Febrile Illness, Melioidosis
Diagnostic Accuracy of the DPP II Assay
Burkholderia pseudomallei is responsible for melioidosis, a disease that can present a range of signs and symptoms and can be treated by a specific drug regimen.
- Conditions
- Acute Febrile Illness, Melioidosis, Diagnoses Disease
- Trial name
- NCT04299412
- Testing
- DPP Fever Panel II assay
- Where
- Australia
- Volunteers
- 104 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Febrile Illness
Knowledge, Attitudes, Perceptions and Behaviors of Healthcare Professionals and the General Population Regarding Vaccination During Febrile Illness
Patients and healthcare professionals often lack adequate information regarding the possibility of vaccinating during febrile illnesses due to limited data.
- Trial name
- NCT06959420
- Testing
- Questionnaire
- Where
- France
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Disorder Characterized by Fever
Scanadu Consumer Health Outcomes (SCOUT) Study
There is a great need within healthcare to develop systems of care that better engage and activate people in their own care before they become patients.
- Trial name
- SCOUT (NCT02134145)
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Scripps Translational Science Institute
Acute Febrile Illness
Advancing Access to Diagnostic Innovation Essential for UHC and AMR Prevention
This study aims to evaluate clinical outcomes and antibiotic prescription patterns following the use of diagnostic algorithms, point of care (PoC) rapid diagnostic tests, and behaviour change interventions in cases of acute…
- Trial name
- Accelerator (NCT04081051)
- Testing
- diagnostic algorithm+Point of care rapid diagnostic tests+ Behavior change ( assessed together as a single package of interventions)
- Where
- 8 sites in Burkina Faso, Ghana and 3 more
- Volunteers
- 17,294 people
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Diarrhea, Pneumonia
Efficacy of Bifidus DR10 and Oligo Saccharides / Micronutrient Fortification of Milk
The purpose of the study is to evaluate effect or fortifying milk with pre and probiotics or with micronutrients on prevention of diarrhea, pneumonia and other childhood illnesses and improvement in growth and development.
- Conditions
- Diarrhea, Pneumonia, Febrile Illness, Growth
- Trial name
- NCT00255385
- Testing
- Micronutrient (Zinc and Iron) fortification, Pre and Probiotic fortification
- Where
- India
- Volunteers
- 1,200 people
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Vaccine
Impact of Vaccines on Antimicrobial Microbial Resistance
Vaccination is a potentially critical component of efforts to arrest development and dissemination of antimicrobial resistance (AMR), though little is known about vaccination impact within low-income and middle-income countries.
- Trial name
- IVAR (NCT06450379)
- Where
- Malawi
- Volunteers
- 13,200 people, healthy volunteers welcome
- Sponsor
- Malawi Liverpool Wellcome Programme
Malaria, Febrile Illness
Malaria Diagnostic Testing and Conditional Subsidies to Target ACTs in the Retail Sector: the TESTsmART Trial AIM 1
The TESTsmART Trial consists of two main aims. The overall goal of the two aims is to investigate the impact of malaria rapid diagnostic test (mRDT) subsidies and conditional artemisinin combination therapy (ACT) subsidies on the…
- Trial name
- TESTsmART (NCT03810014)
- Testing
- Conditional ACT subsidy, Arm 1 levels, Conditional ACT subsidy, Arm 2 levels, Conditional ACT subsidy, Arm 3 levels
- Where
- Kenya
- Volunteers
- 842 people
- Sponsor
- Duke University