Clinical trials: Disorder Heart
Cardiac Arrest
Mild Versus Moderate Therapeutic Hypothermia in Out-of-hospital Cardiac Arrest Patients
This trial is currently a single-center, randomized, double-blind investigator initiated prospective clinical trial initiated at the University of Ottawa Heart Institute (UOHI).
- Trial name
- CAPITALCHILL (NCT02011568)
- Testing
- Therapeutic Hypothermia
- Where
- Canada
- Volunteers
- 389 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Venous Thrombosis, Pulmonary Embolism
Assessment of International Normalized Ratio (INR) Prolongation in Patients Treated Simultaneously With Warfarin and Cephalosporins
Many drug interactions with Warfarin are well documented in the literature, including interactions with a variety of antibiotics.
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation
- Trial name
- NCT01857050
- Volunteers
- 236 people
- Sponsor
- Meir Medical Center
Heart Failure
The Study of Heart Failure With Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-HF)
The purposes of the study is to evaluate the safety and efficacy of human umbilical cord mesenchymal stem cells (hUC-MSC) in treating heart failure patients
- Trial name
- NCT03180450
- Testing
- Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), conventional treatment
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Cardiovascular Diseases, Heart Diseases
Epidemiology of Cardiovascular Risk Factors in Women (Healthy Women Study)
To determine cardiovascular risk factors and the change in risk factors during and following the menopause.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Depression, Carotid Artery Diseases
- Trial name
- NCT00005160
- Volunteers
- 532 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Bacterial Overgrowth Syndrome Small Bowel, Heart Failure with Preserved Ejection Fraction
Rifaximin and Cardiac Function in Patients with Heart Failure with Preserved Ejection Fraction
Single-center, double-blind, randomized, controlled intervention study of the effect of correction of bacterial overgrowth syndrome in the small intestine (SIBO) on cardiac function in patients with heart failure with preserved…
- Trial name
- SIBO-HFpEF (NCT06652087)
- Testing
- Rifaximin, Standard HFpEF treatment
- Where
- Russia
- Volunteers
- 40 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Coronary Artery Disease, Atherosclerosis
Coronary Artery Geometry and the Severity of Coronary Atherosclerosis
The purpose of this study is to investigate the potential association of coronary artery geometry, based on coronary CT angiography (CCTA), with the complexity and the severity of coronary atherosclerosis.
- Conditions
- Coronary Artery Disease, Atherosclerosis, Atherosclerotic Plaque, Stable Angina
- Trial name
- GEOMETRY-CTA (NCT04185493)
- Testing
- CCTA
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- Aristotle University Of Thessaloniki
Coronary Artery Disease, Myocardial Ischemia
Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)
To assess the feasibility of coronary computed tomography angiography (CTA) and fractional flow reserve derived from CTA (FFRCT) to replace invasive coronary angiography (ICA) as a surgical guidance method for planning and…
- Conditions
- Coronary Artery Disease, Myocardial Ischemia, Coronary Disease, Heart Diseases
- Trial name
- NCT04142021
- Testing
- Coronary computed tomography angiography
- Where
- 3 sites in Belgium, Germany and 1 more
- Volunteers
- 114 people
- Sponsor
- National University of Ireland, Galway, Ireland
Ischemic Heart Disease, Cardiac Rehabilitation
A New Cardiac Rehabilitation Treatment in the Application of Ischemic Heart Disease
Cardiac rehabilitation is an important link in cardiovascular disease. This study mainly explores the effectiveness of new cardiac rehabilitation therapy (early respiratory rehabilitation, phase I rehabilitation, exercise…
- Trial name
- NCT06681506
- Testing
- Metronomic breathing, exercise rehabilitation, external counterpulsation, extracorporeal shock wave., bedside rehabilitation and breathing, balance, flexibility, movement rehabilitation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai 10th People's Hospital
Heart Failure
SCREEN-HFI (SCReening Evaluation of the Evolution of New Heart Failure Intervention Study)
Individuals who were a part of the investigators Screen-HF study (NCT00400257) whose BNP level are in the top quintile will be offered participation in this study.
- Trial name
- NCT00604006
- Testing
- Spironolactone
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Monash University
Death, Sudden, Cardiac, Ventricular Fibrillation
DISCOVERY: Diagnostic Data and Genetic Polymorphisms in ICD Patients.
To prospectively evaluate if the analysis of genetic polymorphisms can be used to identify patients at risk of ventricular tachycardia.
- Conditions
- Death, Sudden, Cardiac, Ventricular Fibrillation, Tachycardia, Atrial Fibrillation
- Trial name
- DISCOVERY (NCT00478933)
- Testing
- Defibrillator, Dual Chamber ; Implantable, Blood sampling
- Volunteers
- 1,223 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
ST-segment Elevation Myocardial Infarction
Optimal Coronary Flow After PCI for Myocardial Infarction - a Pilot Study
In this study the investigators test the hypothesis that alteplase given intra coronary after PCI reduce infarct size in patients with ST-elevation myocardial infarction(STEMI) and impaired microvascular function defined as a…
- Trial name
- OPTIMAL (NCT02894138)
- Testing
- alteplase
- Where
- Sweden
- Volunteers
- 80 people
- Sponsor
- Vastra Gotaland Region
COPD
Finger Wearable Device to Monitor Heart Rate Variability and Oxygen Saturation
Introduction: Chronic obstructive airway disease (COPD) is common condition in old age and the perception of hypoxia is often impaired in some COPD patients.
- Trial name
- NCT03268538
- Where
- Hong Kong
- Volunteers
- 277 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Myocardial Infarction
Red Cell Distribution Width,,NT-proBNP and cTnT in Acute Myocardial Infraction Patient
the study is to investigate the relationship of several parameters of complete blood count (CBC) including RDW with N-terminal pro-B-type natriuretic peptide (NT-proBNP) and cardiac troponin T (cTnT) in a cohort of acute…
- Trial name
- NCT05595278
- Testing
- (CBC) ,(NT-proBNP) ,(cTnT)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Sohag University
Coronary Artery Disease
In Vitro Pharmacodynamic Effects of Cangrelor in Ticagrelor Treated Patients
Cangrelor is a potent intravenous P2Y12 receptor inhibitor with rapid onset and offset of action associated with a greater reduction in ischemic events, including stent thrombosis, in patients undergoing stent procedures who have…
- Trial name
- NCT02081443
- Testing
- Ticagrelor 180mg, Ticagrelor 90mg
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Florida
Heart Failure
Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure
To describe and compare the symptom burden in cancer patients with concurrent diagnosis of heart failure (HFrEF compared to HFpEF).
- Trial name
- NCT06656715
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- M.D. Anderson Cancer Center
Fetal Heart Rate Variability
Fetal Evaluation at Term Using Statistical ECG Signal Processing (FETUSES)
Background The fetal heart rate (FHR) is commonly monitored during labor to detect early fetal acidosis. FHR variability is traditionally investigated using Fourier transform, however, fetal conditions differ from adults (higher…
- Trial name
- FETUSES (NCT02835417)
- Volunteers
- 3,563 people
- Sponsor
- Hospices Civils de Lyon
Carcinoid Heart Disease
Development and Progression of Carcinoid Heart Disease in a Cohort of Adult Patients With Neuroendocrine Tumors
Carcinoid Heart Disease (CHD) is a rare form of heart disease, occurring in over 50% of the patients with carcinoid syndrome. Pathophysiology, prognostic factors of development of Carcinoid Heart Disease and progression of…
- Trial name
- CRUSOE-NETs (NCT03498040)
- Testing
- Study of the occurrence of Carcinoid Heart Disease
- Where
- 19 sites in France
- Volunteers
- 670 people
- Sponsor
- Hospices Civils de Lyon
Coronary Disease
Chest Pain, Illness Perception Compliance and Psychosocial Outcome After Coronary Arteriography
Chest pain, illness perception compliance and psychosocial outcome after coronary arteriography. A comparison between patients which were diagnosed with slow coronary flow and patients who have been diagnosed with coronary artery…
- Trial name
- NCT00787540
- Where
- Israel
- Volunteers
- 160 people
- Sponsor
- Hillel Yaffe Medical Center
Atrial Fibrillation (AF)
AF Screening in Patients With Abnormal Echocardiographic Parameters
To evaluate the feasibility of specific echocardiographic parameters as criteria for AF screening and to determine the AF detection yield of scheduled extended ECG monitoring compared to contemporary care.
- Trial name
- SAFE-ECHO (NCT07278089)
- Testing
- study arm
- Where
- Taiwan
- Volunteers
- 3,000 people
- Sponsor
- Tze-Fan Chao
Atrial Fibrillation
Reduction in Arrhythmia Burden With Left Atrial Posterior Wall Ablation for Persistent AF
RABLAP-AF will compare pulmonary vein isolation (PVI) in combination with posterior wall isolation (PWI) for patients with persistent atrial fibrillation (AF).
- Trial name
- RABLAP-AF (NCT05195268)
- Testing
- Intracardiac Catheter Ablation
- Where
- United Kingdom
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
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