Clinical trials: Disorder Heart
Out-Of-Hospital Cardiac Arrest, Foreign Body Aspiration
Foreign Body Airway Obstruction, Incidence, Survival EMS-treatment and First Aid Treatment by Laypersons
Background: Foreign body airway obstruction (FBAO) is often described as an uncommon cause of Out of Hospital Cardiac Arrest (OHCA) accounting for approximately 1.4% of all OHCA.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Foreign Body Aspiration, Cardiopulmonary Arrest
- Trial name
- NCT04279860
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Emergency Medical Services, Capital Region, Denmark
Healthy, Arrhythmia
Prospective Study to Validate the Clinical Accuracy of the Norbert Device to Measure Pulse Rate
The study will evaluate the mean average error (MAE) of measuring pulse rate using the Norbert Device (ND) as compared to a reference heart rate measured using an electrocardiogram (ECG).
- Trial name
- NCT05640323
- Testing
- Norbert Device
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Norbert Health
Hypertrophic Cardiomyopathy
Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)
The investigators are trying to find out how common sleep apnea is in hypertrophic cardiomyopathy. The purpose of this study is to see if sleep apnea is common in hypertrophic cardiomyopathy and if its presence is associated with…
- Trial name
- NCT03327623
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Aortic Valve Stenosis
Added Value of Patient-specific Computer Simulation in Transcatheter Aortic Valve Implantation (TAVI)
Transcatheter aortic valve implantation is increasingly used to treat patients with severe aortic stenosis who are at increased risk for surgical aortic valve replacement and is projected to be the preferred treatment modality.
- Trial name
- TAVIguide (NCT03196596)
- Testing
- Computer simulation
- Where
- 5 sites in Belgium, Denmark and 3 more
- Volunteers
- 80 people
- Sponsor
- Erasmus Medical Center
Mitral Regurgitation, Tricuspid Regurgitation
Combined Mitral and Tricuspid Versus Isolated Mitral Transcatheter Edge-to-Edge Repair for Mitral Regurgitation With Tricuspid Regurgitation (DUAL-TEER Trial)
This study aims to investigate the efficacy and safety of combined mitral and tricuspid transcatheter edge-to-edge repair (TEER) versus isolated mitral TEER in the treatment of patients with mitral regurgitation (MR) combined…
- Trial name
- NCT07349888
- Testing
- Transcatheter Edge-to-Edge Repair (TEER) System
- Volunteers
- 404 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Coronary Disease
"L-Sandwich" Strategy in the True Coronary Bifurcation Lesions
The treatment of coronary bifurcation lesions continue to remain challenges. Due to the complexity of the anatomical structure and the limitations of imaging, there are poor attachment and under-expansion of the stent at the…
- Trial name
- L-Sandwich (NCT04753827)
- Testing
- Drug eluting stent, Durg coated balloon
- Where
- China
- Volunteers
- 107 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Angioplasty, Chronic Coronary Occlusion
XIENCE V Everolimus Eluting Coronary Stent System (EECSS) China: Post-Approval, Single-Arm Study
This is a prospective, observational, single-arm, open-label, multicenter, postapproval registry study in China. The purpose of this study is to: Evaluate the continued safety and effectiveness of the XIENCE V EECSS in a cohort…
- Conditions
- Angioplasty, Chronic Coronary Occlusion, Stent Thrombosis, Vascular Disease
- Trial name
- XV CHINA SAS (NCT01249027)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent System (EECSS)
- Where
- United States
- Volunteers
- 2,605 people
- Sponsor
- Abbott Medical Devices
Diabetes Mellitus, Hypertension
Evidence-based Laboratory Test Order Sets in Primary Care
Cluster randomised controlled trial to evaluate what the effect is of evidence-based order sets aimed at five indications on the appropriateness of laboratory test ordering in primary care.
- Conditions
- Diabetes Mellitus, Hypertension, Cardiovascular Diseases, Fatigue
- Trial name
- NCT02950142
- Testing
- CPOE with order sets for lab testing, CPOE without order sets for lab testing
- Where
- Belgium
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Atrial Fibrillation
New Formulations of Propafenone to Treat Atrial Fibrillation
Propafenone is a currently used medicine to treat atrial fibrillation and is a mixture of two compounds, (R)-propafenone and (S)-propafenone.
- Trial name
- NCT02710669
- Testing
- (R)-propafenone, (S)-Propafenone
- Where
- United States
- Volunteers
- 193 people
- Sponsor
- Vanderbilt University
Atrial Fibrillation (Prevention of Stroke)
Real-Life Evidence on Stroke Prevention in SPAF
To obtain a better understanding on the comparative effectiveness of rivaroxaban and vitamin K antagonists (VKA) for stroke prevention in patients with non-valvular atrial fibrillation (SPAF) in a real-life setting
- Trial name
- RELIEF (NCT02485873)
- Testing
- Rivaroxaban (Xarelto, BAY59-7939), Vitamin K antagonists
- Where
- Germany
- Volunteers
- 8,607 people
- Sponsor
- Bayer
Atrial Fibrillation, Atrial Flutter
Potassium Infusion for Conversion of Atrial Fibrillation/-Flutter
Atrial fibrillation is a condition in which the heart's upper chambers, the atria, contract at an abnormally rapid rate. It is a common type of arrhythmia, and occurs in 1-2% of the general population.
- Trial name
- NCT01818583
- Testing
- Potassium chloride, Glucose 50 MG/ML
- Where
- Norway
- Volunteers
- 143 people
- Sponsor
- Diakonhjemmet Hospital
Aortic Valve Stenosis
Medtronic Evolut Transcatheter Aortic Valve Replacement in Low Risk Patients
The study objective is to demonstrate that the safety and effectiveness of the Medtronic TAVR system as measured by rates of all-cause mortality or disabling stroke at two years is noninferior to SAVR in the treatment of severe…
- Trial name
- NCT02701283
- Testing
- Medtronic Transcatheter Aortic Valve Replacement Systems, Surgical Aortic Valve Replacement (SAVR)
- Where
- 87 sites in United States, Australia and 5 more
- Volunteers
- 2,223 people
- Sponsor
- Medtronic Cardiovascular
Paroxysmal Atrial Fibrillation
Effect of Cavotricuspid Isthmus Ablation in Patients Without History of Typical Flutter During Ablation
It has been demonstrated that successful cavotricuspid isthmus ablation may be effective in preventing paroxysmal atrial fibrillation. However, the effectiveness of only isthmus ablation on atrial fibrillation itself is unclear.
- Trial name
- NCT02031705
- Testing
- cavotricuspid isthmus ablation, control group
- Where
- South Korea
- Volunteers
- 366 people
- Sponsor
- Yong Seog Oh
Cardiac Arrest (CA)
Self-training and Resuscitation Techniques: Evaluation of the Performance and Impact on the Quality of Cardiopulmonary Resuscitation (CPR)
Cardiac arrest (CA) remains one of the leading causes of death worldwide, and its incidence continues to increase. The median survival rate following in-hospital cardiac arrest in France is 19%.
- Trial name
- ATIPIQ (NCT07820605)
- Where
- France
- Volunteers
- 265 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Patient Participation, Heart Defects, Congenital
Liver Disease, Myocardial Fibrosis and Collaterals in the Adult Fontan Patient a Metabolomics and Proteomics Approach
Out objective is to identify the mechanisms that promote hepatic and myocardial fibrosis, and collateral vessel formation in patients with complex congenital heart disease and Fontan circulation.
- Conditions
- Patient Participation, Heart Defects, Congenital, Liver Diseases, Collateral Circulation, Any Site
- Trial name
- NCT04764305
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Kidney Injury, Acute
A Machine Learning Prediction Model for Postoperative Acute Kidney Injury in Non-Cardiac Surgery Patients
Primary objectives of this study is to develop and validate a predictive model for acute kidney injury after non-cardiac surgery based on machine learning.
- Trial name
- NCT07030166
- Testing
- No intervention measures were used.
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Lanyue Zhu
Cardiovascular Disease
Effect of Wine Consumption on Cardiovascular Markers in CHDs Patients
Many epidemiological studies support that 20-30gr of alcohol consumption per day is related with lower risk for cardiovascular diseases, heart attack as well as mortality related to these diseases.
- Trial name
- NCT04438122
- Testing
- Cabernet Sauvignon, Tsipouro
- Where
- Greece
- Volunteers
- 57 people
- Sponsor
- Harokopio University
Mitral Stenosis
Role of Ivabradine on Heart Rate and Quality of Life in Patients With Mitral Stenosis in Sinus Rhythm
Mitral stenosis, a condition characterized by narrowing of the mitral valve orifice, remains a significant cause of morbidity and mortality worldwide, particularly in regions where rheumatic fever is endemic.
- Trial name
- NCT06371222
- Testing
- Ivabradine, Beta blocker
- Where
- Bangladesh
- Volunteers
- 42 people
- Sponsor
- Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
Congestive Heart Failure
Engaging Patients in Heart Failure Management
An interventional study to empower congestive heart failure patients who have a cardiac resynchronization therapy-cardiac implantable electronic device (CRT-CIED) by using a personal health record (PHR) to directly message them…
- Trial name
- NCT02682251
- Testing
- PHR Messaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Parkview Health
Heart; Dysfunction Postoperative, Cardiac Surgery, Disorder; Heart, Functional, Postoperative, Cardiac Surgery
Influence of Anesthesia on Mechanical Efficiency of Left Ventricle in Patients Undergoing Open Heart Surgery
The aim of the study is to delineate and compare the changes in coupled mechanical properties of left ventricle and arterial vascular bed caused by two popular anesthetic protocols commonly used in cardiac surgery (intravenous…
- Trial name
- NCT01397331
- Testing
- Isoflurane, Propofol
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Sheba Medical Center
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