Clinical trials: Disorder Heart
Hospital Readmission, Pneumonia
Mobile Integrated Healthcare and Community Paramedicine
Background: Initially conceived of as a method to address healthcare needs of underserved rural populations, Mobile Integrated Healthcare and Community Paramedicine (MIH/CP) is a new model of inter-professional, community-based…
- Conditions
- Hospital Readmission, Pneumonia, Myocardial Infarction, COPD
- Trial name
- NCT05061433
- Testing
- Mobile Integrated Healthcare/Community Paramedicine (MIH/CP) Support
- Volunteers
- 44 people
- Sponsor
- Rhode Island Hospital
Coronary Artery Perforation, Coronary Stent Occlusion
Glasgow Natural History Study Of Covered Coronary Interventions
Covered stents (CS) are a potentially lifesaving treatment for grade III coronary perforation but delivery can be challenging, and the long-term durability and safety including risk of acute stent thrombosis are unknown.
- Conditions
- Coronary Artery Perforation, Coronary Stent Occlusion, Stent Thrombosis
- Trial name
- GNOCCI (NCT03862352)
- Testing
- Covered coronary stent
- Where
- United Kingdom
- Volunteers
- 161 people
- Sponsor
- NHS National Waiting Times Centre Board
Pneumonia, Interstitial, Cancer Patients
Study of of Oxygen Nebulized Inhalation EGCG in Cancer Patients With New Coronary Pneumonia
Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a wide variety of actions, such as anti-inflammatory, anti-fibrotic, pro-apoptotic, anti-tumorous, and metabolic effects via modulation of a…
- Trial name
- NCT06924749
- Testing
- EGCG
- Where
- 2 sites in China
- Volunteers
- 111 people
- Sponsor
- Shandong Cancer Hospital and Institute
Heart Diseases, Cardiovascular Diseases
Acute Cardiac Ischemia in Women in the ACI/TIPI Trial
To conduct a series of five inter-related studies on acute cardiac ischemia (ACI) in women.
- Conditions
- Heart Diseases, Cardiovascular Diseases, Angina Pectoris, Myocardial Ischemia
- Trial name
- NCT00005701
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure, Hyperuricemia
Prednisone for Heart Failure Patients With Hyperuricemia
Hyperuricemia is a very common finding in patients with heart failure. It is usually related to diuretic use and deteriorated renal function.
- Trial name
- PUSH-PATH-2 (NCT02129764)
- Testing
- Prednisone, Allopurinol
- Where
- China
- Volunteers
- 205 people
- Sponsor
- Hebei Medical University
Atrial Fibrillation Paroxysmal
Esophageal Temperature During PVI Using Q-DOT Micro
This study will assess how two different ablation strategies, using two different ablation catheters during catheter ablation for paroxysmal atrial fibrillation, affect the temperature of the esophagus during ablation, and the…
- Trial name
- NCT06392932
- Testing
- QDOT Micro ablation catheter, ST SF ablation catheter
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Cedars-Sinai Medical Center
Heart Failure
TEXT4HF: A Randomized Controlled Trial of a Tailored Text Messaging Intervention to Improve Self-Care in Older Adult Patients With Heart Failure
The goal of this study is to determine whether an individually tailored text messaging intervention can improve self-care in older adult patients with heart failure.
- Trial name
- TEXT4HF (NCT06473532)
- Testing
- TEXT4HF
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Illinois Chicago
Coronary Artery Disease, Valvular Heart Disease
The ABC Trial Does All-Blood Cardioplegia Prevent Blood Transfusion in Cardiac Surgery? A Single Centre Pilot Study
This study is a single centre pilot for a randomized trial comparing all-blood cardioplegia to more dilute 4:1 blood cardioplegia during cardiac surgery.
- Trial name
- ABC (NCT01623193)
- Testing
- All-blood cardioplegia, Standard cardioplegia
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Pam Trenholm
Hypertension, Pulmonary, Cardiac Failure
Levosimendan Administration in Pulmonary Hypertension
The aim of the study is to examine the pharmacokinetics and pharmacodynamic properties of Levosimendan in cardiac surgery patients with pulmonary hypertension and impaired right ventricular function.
- Conditions
- Hypertension, Pulmonary, Cardiac Failure, Pulmonary Vascular Resistance Abnormality
- Trial name
- Levosim-PH (NCT04599816)
- Testing
- levosimendan at a dose of 3 mcg/kg, levosimendan at a dose of 6 mcg/kg, levosimendan at a dose of 12 mcg/kg
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aretaieion University Hospital
Heart Failure
Forxiga HF General Drug Use-Results Study
To capture safety when Forxiga is administered to patients with HF in clinical practice after launch.
- Trial name
- NCT04865406
- Where
- 45 sites in Japan
- Volunteers
- 1,221 people
- Sponsor
- AstraZeneca
Congenital Heart Disease With Systemic Right Ventricle
Study of Adaptation of the Right Ventricle to Systemic Afterload
the first purpose of the study is to determine the adaptative mechanisms of right ventricle (RV) to systemic afterload, and the mechanisms of RV failure, in patients with congenital heart disease and subaortic RV, using cardiac…
- Trial name
- STARS (NCT02066506)
- Testing
- asymptomatic group, symptomatic group
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Aortic Stenosis
Prediction of Long-term Outcome in Aortic Stenosis After Valve Intervention
Patients with severe aortic stenosis accepted for transcatheter intervention or open surgery are included before the intervention, and then followed up with clinical visits during the first year after intervention.
- Trial name
- NCT05629104
- Testing
- There is no intervention since it is an observational study patients are treated according to clinical praxis
- Where
- Sweden
- Volunteers
- 300 people
- Sponsor
- Uppsala University
Coronary Disease
Intervention in Lifestyle and Therapeutic Adherence After Coronary Event Based on Web Application
Ischemic heart disease is the most frequent cause of mortality in the surrounding countries. Once a coronary event is over, there is a high risk of readmission, recurrence and, mortality, attributed to a sub-optimal control of…
- Trial name
- EVITE (NCT04118504)
- Testing
- Mobile application
- Where
- Spain
- Volunteers
- 240 people
- Sponsor
- Instituto de investigación e innovación biomédica de Cádiz
Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension
Evolution of Hypoxic Burden and Sympathetic/Parasympathetic Balance in Patients With Pulmonary Hypertension
Background and Rationale: Sleep-disordered breathing and nocturnal hypoxemia are highly prevalent in patients with precapillary pulmonary hypertension (PH), and current guidelines recommend systematic sleep assessment in this…
- Conditions
- Precapillary Pulmonary Hypertension, Pulmonary Arterial Hypertension, Sleep-disordered Breathing, Nocturnal Hypoxemia
- Trial name
- HRV&PH (NCT07464184)
- Testing
- Standard Clinical and Functional Assessment, Overnight Polysomnography
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Rouen
Depression, Diabetes Mellitus Type 2
Pilot Study of a Self-help Intervention for Depression in Patients With a Chronic Disease
A feasibility pilot trial of the self-help, "Cognitive behavioural therapy" based "Living Life to the Full" Materials for use by patients with diabetes type 2 and / or coronary heart disease.
- Conditions
- Depression, Diabetes Mellitus Type 2, Coronary Heart Disease
- Trial name
- NCT00854984
- Testing
- Living Life to the Full
- Where
- 2 sites in United Kingdom
- Volunteers
- 49 people
- Sponsor
- University of Edinburgh
Respiratory Function Tests，Heart Function Tests, Cardiopulmonary Function
Xiangya Cardiopulmonary Health and Disease Cohort
Xiangya Cardiopulmonary Health and Disease Cohort (XY-CPHDC) is a non-intervention study grounded in real-world data. It is designed as a bidrectional clinical cohort combined retrospective and prospective design, in order to…
- Trial name
- XY-CPHDC (NCT06972784)
- Where
- China
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Xiangya Hospital of Central South University
Coronary Artery Disease, Microvascular Coronary Artery Disease
Inclusive Invasive Physiological Assessment in Angina Syndromes Registry
This study evaluates the prognostic value and potential therapeutic impact of combined pressure and flow measurements in the evaluation of epicardial coronary stenosis and microvascular function.
- Trial name
- ILIAS Registry (NCT04485234)
- Testing
- Resting distal coronary to aortic pressure ratio, Fractional flow reserve, Coronary Flow Reserve, Microvascular resistance
- Where
- 12 sites in United States, Denmark and 5 more
- Volunteers
- 2,322 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Aortic Valve Stenosis
Analgesia in Patients Undergoing Transfemoral Transcatheter Aortic Valve Implantation (TF-TAVI)
Ilioinguinal and iliohypogastric (ILIH) nerve blocks are frequently performed for analgesia in inguinal surgery. The investigators hypothesized that preoperative ultrasound-guided ilioinguinal and iliohypogastric (ILIH) nerve…
- Trial name
- TF-TAVI (NCT03863899)
- Testing
- Nerve block, Local infiltration, TAVI
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Medical University of Gdansk
Cardiomyopathy, Heart Failure
Bone Marrow Derived Mesenchymal Stem Cells in Improving Heart Function in Patients With Heart Failure Caused by Anthracyclines
This randomized pilot phase I trial studies the side effects and best method of delivery of bone marrow derived mesenchymal stem cells (MSCs) in improving heart function in patients with heart failure caused by anthracyclines (a…
- Trial name
- NCT02408432
- Testing
- Laboratory Biomarker Analysis, Standard of Care, Mesenchymal Stem Cell Transplantation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- M.D. Anderson Cancer Center
Saphenectomy, No Touch
Morbidity of Conventional and No-touch Saphenectomy in Coronary Artery Bypass Grafting.
A clinical research project will be carried out that will consist of a non-inferiority study. The objective is to compare the morbidity of two different surgical techniques for the extraction of the internal saphenous vein…
- Conditions
- Saphenectomy, No Touch, Coronary Artery Disease, Cardiovascular Diseases
- Trial name
- TNT (NCT06496321)
- Testing
- Conventional Saphenous vein harvest, No touch Saphenous vein harvest
- Where
- Uruguay
- Volunteers
- 52 people
- Sponsor
- Instituto Nacional de Cirugia Cardiaca, Uruguay
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