Clinical trials: Disorder Heart
Atrial Fibrillation, Atrial Flutter
Strategies for the Management of Atrial Fibrillation in patiEnts Receiving Dialysis 2 (SAFE-D2)
People receiving dialysis are more likely to develop atrial fibrillation (AF), an irregular heartbeat that increases the risk of stroke.
- Conditions
- Atrial Fibrillation, Atrial Flutter, End Stage Kidney Disease (ESRD), Dialysis Patients
- Trial name
- SAFE-D2 (NCT07779746)
- Testing
- Eliquis, No oral anticoagulation
- Volunteers
- 848 people
- Sponsor
- Unity Health Toronto
Cardiac Amyloidosis
Prevalence of Cardiac Thrombi in Cardiac Amyloidosis
Cardiac amyloidosis (CA) is an infiltrative disease characterized by deposits of amyloid proteins of genetic or acquired origin (often in elderly patients), leading to heart failure and arrhythmias.
- Trial name
- CATICA (NCT07648303)
- Testing
- Cardiac CT scan with contrast
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
ITV Sosu Aortique, Cardiac Output, High
PLR in a Good Helath After 24 Week of Preganancy
fluid resuscitation is one of the bases of strategies in ICU to take in charge patients , one of the technique to evaluate preload charge , is Passive leg raising, that allows reliable prediction of fluid responsiveness even in…
- Conditions
- ITV Sosu Aortique, Cardiac Output, High, PLR
- Trial name
- NCT05646342
- Testing
- Measure of CO by ECHocardiac Machine
- Volunteers
- 60 people
- Sponsor
- Mohammed VI University Hospital
Aortic Valve Stenosis
Transcatheter Aortic Valve Replacement (TAVR) Double Balloon Valvuloplasty
In this study, the investigators evaluate whether routine double inflation of the valve could have a lasting impact. The investigators hypothesize that a routine second reinflation of the balloon, or "double tap", will improve…
- Trial name
- NCT05189886
- Testing
- Double Balloon Valvuloplasty in TAVR
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Community Memorial Health System
Pulmonary Hypertension, Right Ventricular Dysfunction
Feasibility Trial for a Right Ventricular Failure Platform Trial
The primary objective of the CRAVE feasibility trial is to assess the feasibility of conducting a larger CRAVE platform trial by performing a randomized trial of 30 participants with pulmonary hypertension and right ventricular…
- Conditions
- Pulmonary Hypertension, Right Ventricular Dysfunction, Right Heart Failure
- Trial name
- CRAVE (NCT06570473)
- Testing
- Empagliflozin, Ranolazine
- Where
- 5 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Coronary Disease, Acute Coronary Syndrome
Clinical Study Protocol - Debris Interventional Removal in ACS (DESIRE-ACS)
DebriS Interventional REmoval in ACS (DESIRE-ACS) Study to assess the safety and performance of the ECA Bell balloon in subjects undergoing coronary percutaneous interventions.
- Conditions
- Coronary Disease, Acute Coronary Syndrome, Coronary Occlusion
- Trial name
- DESIRE-ACS (NCT02325869)
- Testing
- Bell Balloon Catheter
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Angioslide Ltd.
Atrial Fibrillation
Blood Pressure Assessment in Atrial Fibrillation
This is a cross-sectional study including patients with permanent atrial fibrillation. Assessment will include: clinic blood pressure measurements (mercury sphygmomanometer and automated oscillometric device) 24-hour ambulatory…
- Trial name
- NCT01088269
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Intimal Proliferation, Immunosuppression
Intracoronary Analysis of Cardiac Allograft Vasculopathy by Means of Optical Coherence Tomography
Randomized prospective multi-center imaging study which investigates the impact of different immunosuppressive protocols (Everolimus (Certican®) or Mycophenolate mofetil (CellCept®)) on cardiac allograft vasculopathy (CAV) in…
- Trial name
- OCTandCAV (NCT02254668)
- Testing
- Protocol with Everolimus (Certican®), Protocol with Mycophenolate mofetil (CellCept®)
- Where
- Switzerland
- Volunteers
- 278 people
- Sponsor
- University of Zurich
Tachycardia, Ventricular, Arrhythmia, Ventricular
Effectiveness of the EMPOWER™ Modular Pacing System and EMBLEM™ Subcutaneous ICD to Communicate Antitachycardia Pacing
The MODULAR ATP Clinical Study is designed to demonstrate safety, performance, and effectiveness of the Modular Cardiac Rhythm Management (mCRM) Therapy System.
- Trial name
- MODULAR ATP (NCT04798768)
- Testing
- mCRM Therapy System
- Where
- 38 sites in United States, Austria and 7 more
- Volunteers
- 297 people
- Sponsor
- Boston Scientific Corporation
Fibromyalgia Syndrome
The Effect of Neural Therapy on Heart Rate Recovery, Cardiac Parameters and Pain in Fibromyalgia
Background: Autonomic dysfunction has been observed in patients with fibromyalgia and is associated with symptoms and arrhythmia development in such patients.The investigators can analyze dysautonomia using heart rate recovery…
- Trial name
- NCT06795750
- Testing
- neural therapy, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Uşak University
Resting Heart Rate, Blood Glucose Control
Assessing the Effects of Cool Roofs on Indoor Environments and Health
Ambient air temperatures in Asian, Latin American, African, and Pacific climate hotspots have broken record highs in 2024, driven by man-made climate change. Solutions are needed to reduce heat exposure in communities.
- Conditions
- Resting Heart Rate, Blood Glucose Control, Depression, Heat-related Symptoms
- Trial name
- REFLECT (NCT06579950)
- Testing
- Cool roof
- Where
- 5 sites in Burkina Faso, Fiji and 3 more
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- Aditi Bunker
Coronary Heart Disease
Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease
The purpose of this study is to compare the efficacy between two lipid lowering treatments, rosuvastatin (10-40 mg) and atorvastatin (20-80 mg) in reducing low-density lipoprotein cholesterol (LDL-C) levels after 16 weeks of…
- Trial name
- NCT00235950
- Testing
- Rosuvastatin or atorvastatin or simvastatin and clopidogrel
- Where
- 18 sites in Sweden
- Volunteers
- 255 people
- Sponsor
- AstraZeneca
Acute Decompensated Heart Failure, COPD Exacerbation
Use of ΔIVC for Early Diagnosis of AHF in AECOPD
Acute Heart failure (AHF) is a common cause of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). This association is frequently underestimated with regard to the difficulty of clinical diagnosis.
- Trial name
- NCT05327374
- Testing
- calculation of the inferior vena cava collapsibility index
- Where
- 3 sites in Tunisia
- Volunteers
- 401 people
- Sponsor
- University of Monastir
Coronary Artery Disease
Dynamic Change of Coronary Artery Curvature
The novolimus-eluting DynamX bioadaptor system is composed of 71 µm cobalt-chromium sinusoidal rings connected to each other axially by three S-links Each ring contains three uncaging elements that are positioned at equal…
- Trial name
- DC3 (NCT04936191)
- Testing
- DynamX Bioadaptor
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- National Taiwan University Hospital
Coronary Artery Disease, Myocardial Infarction
Comparison Between Moderate-high Interval Exercise and Moderate Continuous Exercise in an Advanced Cardiac Rehabilitation Program
The research will study the differences between interval training and continuous training among cardiac patients in a cardiac rehabilitation facility. The main objectives are: 1. Functional capacity measures (VO2 max). 2.
- Trial name
- NCT02162290
- Testing
- Interval exercise training, Continuous exercise training
- Where
- Israel
- Volunteers
- 84 people
- Sponsor
- Assaf-Harofeh Medical Center
Cardiovascular Diseases, Diabetes Mellitus, Non-insulin Dependent
Epidemiology of Cardiovascular Disease in Diabetes
To locate and identify genes contributing to the genetic component of subclinical cardiovascular disease (CVD) in Type 2 diabetes and to evaluate the impact of lifestyle and environment on the expression of these genetic…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Non-insulin Dependent, Heart Diseases, Atherosclerosis
- Trial name
- NCT00037297
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Cardiovascular Disease
Heart Attack Prevention Programme for You (HAPPY) London
Diseases of the heart and blood vessels, such as heart attacks and strokes, are very common and can lead to severe disability or death.
- Trial name
- HAPPYLondon (NCT01911910)
- Testing
- Electronic coaching plus standard care
- Where
- United Kingdom
- Volunteers
- 402 people
- Sponsor
- Queen Mary University of London
Atrial Fibrillation
eHealth-based Bavarian Alternative Detection of Atrial Fibrillation: A Randomized Controlled Trial (eBRAVE-AF)
Atrial fibrillation (AF) is the most common arrhythmia in western countries and causes of up to one quarter of ischemic strokes.
- Trial name
- eBRAVE-AF (NCT04250220)
- Testing
- e-Health based strategy: PPG-based screening using a smartphone and ECG patch
- Where
- Germany
- Volunteers
- 4,400 people
- Sponsor
- LMU Klinikum
Heart Failure
Non-invasive Filling Pressure(NIFP) Device Based on Low Frequency Heart Sound in Assessment of Congestion in Heart Failure Patients
Congestion plays a key role in heart failure (HF) trajectory .Clinical congestion refers to the signs and symptoms resulting from elevated cardiac filling pressures.
- Trial name
- NCT06593223
- Testing
- Assess Non-invasive filling pressure(NIFP) in heart failure patients
- Where
- China
- Volunteers
- 400 people
- Sponsor
- The University of Hong Kong-Shenzhen Hospital
Cardio Respiratory Arrest
AiCR : Artificial Intelligence in Cardiac aRrest
The overall incidence of cardiorespiratory arrest in Europe is estimated at 350,000 to 700,000 cases per year. Survival rate is estimated at 10.7% for all rhythm disorders combined.
- Trial name
- AiCR (NCT04462380)
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
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