Clinical trials: Disorder of Blood Gas
Healthy Volunteers, Pathologies for Which paCO2 Monitoring is Crucial, Particularly in the Context of Chronic Obstructive Pulmonary Disease (COPD)
Influence of Temperature on Transcutaneous Blood Gas Diffusion: CAPNOS Project
The measurement of tcpCO2 has many disadvantages: the need for regular calibration (4 to 8 hours) of the sensor, the fact that the sensor heats the skin (risk of burns), the impossibility of measurement in ambulatory and the high…
- Trial name
- CAPNOS (NCT05637138)
- Testing
- tcpCO2 measure, tcpO2 measure, measurement of tissue conductivity to CO2: KS
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Myelomeningocele, Terbutaline Adverse Reaction
In Utero Repair of Myelomeningocele: Atosiban Versus Terbutaline
Myelomeningocele is a malformation with high incidence, and it consists in a neural tube defect. Fetal intrauterine surgery is an alternative for correction, and it improves the prognosis of the fetus, but has an increased risk…
- Conditions
- Myelomeningocele, Terbutaline Adverse Reaction, Pregnancy; Malformation Central Nervous System
- Trial name
- NCT04468568
- Testing
- Atosiban, Terbutaline
- Where
- Brazil
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Hypoxia, Normobaric Hypoxia
Effect of Acute Hypoxia on RIght VEntRicular Function in Healthy Adults.
More and more people are engaging in sports in the mountains, including individuals with heart or lung diseases. At the same time, such diseases are becoming more common in Switzerland.
- Conditions
- Hypoxia, Normobaric Hypoxia, Altitude Hypoxia, Right Heart Function
- Trial name
- RIVER-H (NCT07431567)
- Testing
- Normobaric Hypoxia
- Where
- 2 sites in Switzerland
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mona Lichtblau
Disorder of Blood Gas, Bleeding Disorder
Blood Gas and Bleeding Disorders in Healthy Volunteers Exposed to Nitroglycerin and Nitrogen Compounds
The aim of the study was to investigate the possible relationship about blood gas and bleeding disorders in healthy volunteers of blasters and no blasters groups of the Italian National Mountain and Cave Rescue who handled…
- Trial name
- NCT04201860
- Testing
- Arterial blood gas analyses and haemostasis measures
- Where
- Italy
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Emiliano Petrucci
Heart Valve Diseases
Effect Of Power Breath Device On Arterial Blood Gases And Diaphragmatic Excursion After Valve Surgery
The aim of this study is to evaluate the effect of power breath device on arterial blood gases, diaphragmatic excursion and the 6 min walk test after cardiac valve surgery.
- Trial name
- NCT06012474
- Testing
- Power breath plus, Incrementing the training load, Diaphragmatic breathing exercises
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy, Cyclists
Effects of Contemporary Cycling Saddle Designs on Penile Transcutaneus Oxygen and Carbon Dioxide Levels in Elite Road Cyclists Riding on a Stationary Trainer
Aim of this research is to compare novel 3D printed cycling saddle with the bestselling saddles from two major cycling manufacturers in terms of effects on penile blood gasses and update these findings on current style of racing…
- Conditions
- Healthy, Cyclists, Blood Gas Monitoring, Transcutaneous, Penile Numbness
- Trial name
- EC-SADDLE (NCT05887193)
- Testing
- Biothesiometry, Transcutaneous blood gas monitoring, Cycling on a home trainer
- Where
- Czechia
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Milan Martínek
Chronic Obstructive Pulmonary Disease, Bronchial Asthma
Influence of Bag Volume Variation on the Reproducibility of Inert Gas Rebreathing
Non-invasive inert gas rebreathing (IGR) based on the Fick Principle showed promising results in the determination of pulmonary blood flow (PBF).
- Conditions
- Chronic Obstructive Pulmonary Disease, Bronchial Asthma, Restrictive Pulmonary Disease
- Trial name
- NCT01762917
- Where
- Germany
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Universitätsmedizin Mannheim
COPD, Healthy Subjects
Sublingual Tonometry to Assess Tissue Perfusion in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Sublingual positioning of a silicon capillary system is applied. After 15 min, while the individual is in resting position with closed mouth and normal tidal breathing through the nose is performed, the silicon capillary system…
- Trial name
- subton (NCT01169506)
- Testing
- sublingual silicon capillary
- Where
- Hungary
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Szeged University
Respiration Disorders
Epidural Analgesia and Postoperative Respiratory Functions (EPAPRES)
Patients operated with posterolateral thoracotomy were enrolled. Post-operative analgesia was provided either by TEA with 0.1% bupivacaine or pethidine based intravenous analgesia (IVA) in our sample population.
- Trial name
- EPAPRES (NCT03643757)
- Testing
- Thoracic epidural analgesia, Bupivacaine
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Yedikule Training and Research Hospital
Preeclampsia, Severe Preeclampsia
Excess Base Comparison Between Pregnant Subjects With Severe Preeclampsia vs. Normotensive Pregnant Women
The study's primary goal is to compare the base excess (BE) values-an indicator of metabolic changes-in two groups of patients at Santo Tomás Hospital: those with severe preeclampsia and healthy, pregnant individuals.
- Trial name
- NCT07265336
- Testing
- Arterial Blood gases
- Where
- Panama
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saint Thomas Hospital, Panama
Abnormal; Birth
Changes of Gas Values in Cord Blood Versus Time and Temperature
The pH levels of a neonatal at his birth are an important factor in establishing the connection between events that occurred during the actual time of birth, to the risk of a significant morbidity development in the future.
- Trial name
- NCT02785367
- Testing
- Cord blood samples
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Chronic Obstructive Pulmonary Disease Exacerbation
Evaluation of Oxygen Delivery Methods in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
To examine the effects of oxygen therapy methods applied as indicated in COPD acute exacerbations on blood gas results and spirometric measurements.
- Trial name
- NCT06561464
- Testing
- EzPAP®, Non-invasive mechanical ventilation (NIMV)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital
Tobacco Smoke Pollution, Maternal Exposure During Pregnancy
Prenatal Tobacco Exposure and Newborn Outcomes: A Maternal Urinary Cotinine Study
Prenatal exposure to tobacco smoke, through either active maternal smoking or secondhand exposure, has been associated with impaired fetal oxygenation, metabolic stress, and adverse early neonatal outcomes.
- Conditions
- Tobacco Smoke Pollution, Maternal Exposure During Pregnancy, Infant, Newborn, Carbon Monoxide Poisoning
- Trial name
- NCT07201181
- Testing
- Maternal Urinary Cotinine Assessment
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Intensive Care Unit Syndrome
The Effect of Prone Position Use Ventilator-Associated Pneumonia in Intensive Care Patients
The aim of this experimental study was to investigate the effect of prone position use on ventilator values, blood gas and ventilator-associated pneumonia in intensive care unit patients.
- Trial name
- prone (NCT05760716)
- Testing
- practicing prone position
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul Arel University
Apnea, Ventilation Therapy; Complications
THRIVE Apneic Ventilation With Standardized Airway Management During General Anesthesia.
Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) denotes the use of high-flow humidified nasal oxygen system (for example Optiflow®) as an alternative ventilation modality for an anesthetized patient without…
- Conditions
- Apnea, Ventilation Therapy; Complications, Respiratory Acidosis
- Trial name
- NCT03797859
- Testing
- Apneic ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet