Clinical trials: Disorder of Circulatory System
Acute Stroke, Ischemic Stroke
Analysing the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke
The main purpose of this trial is to analyse the Effects of Xingnaojing for Mild-to-severe Acute Ischemic Stroke by Metabonomics, proteomics and clinical parameters.
- Trial name
- NCT04813445
- Testing
- Xingnaojing injection
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dongzhimen Hospital, Beijing
Stroke, Stroke, Ischemic
Understanding the Need and Feasibility of Transitional Care Training Program Among Family Caregivers of Geriatric Stroke Survivors in Pakistan
The main intention of the study is to understand the need and feasibility of transitional care training program among family caregivers of geriatric stroke survivors in Pakistan
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- NCT06341881
- Testing
- Transitional Care Training Program
- Where
- 3 sites in Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
PreDiabetes, Obesity
Effect of Mango Consumption on Individuals with Pre-diabetes
This study is designed to explore the effect of mango consumption on glycemic indices, cardiovascular health, and body composition in overweight and obese individuals with prediabetes.
- Trial name
- NCT05571800
- Testing
- Mango
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Florida State University
Foot Ulcer, Diabetic
Reliability of a Diabetic Foot Ulcer Risk Stratification and Referral Algorithm
The main objective of this research study is to validate the St Joseph's Health Care Harmonized Foot Ulcer Assessment and Stratification tool using inter-rater reliability technique to determine if the score would consistently be…
- Trial name
- NCT03370237
- Where
- Canada
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Heart Failure, Diastolic, Edema Brain
Feasibility Study of a New Peripheral Oedema Monitor for Heart Failure
The study aims at assessing the usefulness of the Heartfelt1 device in patients suffering from heart failure, who have peripheral oedema. The device is non-contact and does not requires patient compliance to work.
- Conditions
- Heart Failure, Diastolic, Edema Brain, Decompensated Heartfailure
- Trial name
- NCT02993601
- Testing
- Heartfelt-1, Weighing scales, Medical grading of oedema
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Heartfelt Technologies
Stroke, Spasticity, Muscle
Individualized rTMS Based on fNIRS to Spasticity
Stroke is of high morbidity and mortality, and surviving patients are often unable to take care of themselves because of severe motor dysfunction.
- Conditions
- Stroke, Spasticity, Muscle, Rehabilitation
- Trial name
- NCT05318586
- Testing
- individual rTMS based on fNIRS, Traditional rTMS strategy
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Moyamoya Disease
The Role of m6A RNA Modification in Moyamoya Disease
The purpose of this study is to detect the change of m6A RNA modification from peripheral blood of patients with moyamoya disease, and to assess the relationship between clinical characteristics.
- Trial name
- NCT04696094
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Gestational Diabetes Mellitus, Pregnancy
Gestational Diabetes Mellitus and Cardiovascular Disease: The Role of Vascular Dysfunction
The purpose of this research study is to look at whether there are differences in blood vessel function, risk for developing diabetes (high blood sugar), lipid (blood fat) levels, and levels of other blood markers between black…
- Trial name
- NCT00998712
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Heart Disease, Heart Failure
Investigating Systemic and Local Vascular Responses to Apelin in the Context of Renin-angiotensin Upregulation
The apelin-APJ system is a relatively new discovery. It has generated interest in part due to it's apparent ability to counteract the renin-angiotensin system, which is frequently overactive in many cardiovascular disease.
- Conditions
- Heart Disease, Heart Failure, Vasodilatation
- Trial name
- NCT00901719
- Testing
- Apelin, Acetylcholine, Sodium nitroprusside
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Congenital Adrenal Hyperplasia
Cardiovascular Risk Profile in Patients With Congenital Adrenal Hyperplasia
Treatment with glucocorticoids and mineralocorticoids has changed congenital adrenal hyperplasia (CAH) from a fatal to a chronic lifelong disease.
- Trial name
- cardiohcs (NCT01807364)
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dysglobulinemia
Familial Dysglobulinemia
Multiple Myeloma (MM) is a malignant proliferation of monoclonal plasma cells. Myeloma accounts for almost 14% of all hematologic cancers and is essentially incurable.
- Trial name
- PreFamDys (NCT02853214)
- Testing
- Genetic analysis of peripheral blood samples
- Where
- 47 sites in France
- Volunteers
- 1,868 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Hemorrhoids
Calcium Dobesilate vs Flavonoids for the Treatment of Early Hemorrhoidal Disease
Haemorrhoids are vascular cushions in the anal canal that help in the control of stool. When inflamed they become pathological and may present with protrusion and bleeding.
- Trial name
- NCT02782455
- Testing
- Flavonoids, CDobi
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Services Hospital, Lahore
Stroke, Gait Disorders, Neurologic
Dynamic Ultrasound of the Calf Muscles After Stroke
Muscle behaviour of calf muscles can be studied during dynamic conditions using dynamic ultrasound. In particular, the medial gastrocnemius is suitable for measurements with dynamic ultrasound due to its superficial location.
- Trial name
- Stroke_DynUS (NCT06250478)
- Testing
- Dynamic ultrasound of the calf muscles
- Where
- Belgium
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Atrial Fibrillation
The Effectiveness of Patch-Based Screening for Pre-Symptomatic Atrial Fibrillation to Improve Patient Outcome
The goal of the screening trial is to determine whether early screening for atrial fibrillation improves outcomes, including lowering the chance of death, hospitalization for stroke, blood clots, heart failure, heart attack, and…
- Trial name
- VALIANT-AF-S (NCT06953778)
- Testing
- Zio XT® Patch
- Where
- United States
- Volunteers
- 24,060 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Diabete Type 2, Diabetic Foot
Turkish Validity-Reliability Study of the Diabetic Foot Self-Care Questionnaire
The aim of this study is to evaluate the translation, cross-cultural adaptation and psychometric properties of the Diabetic Foot Self-Care Questionnaire in patients with primary Type 2 Diabetes.
- Trial name
- NCT05404178
- Testing
- Type 2 diabetes group
- Where
- Turkey (Türkiye)
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Harran University
Cerebrovascular Disorders
Neuroprotective and Cardioprotective Effects Of Palm Vitamin E Tocotrienols
The purpose of the study is to assess the neuroprotective, anti atherogenic and hepatoprotective properties of tocotrienols (palm vitamin E) supplementation as determined by white matter lesion load on serial magnetic resonance…
- Trial name
- NCT00753532
- Where
- Malaysia
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Brain Ischemia, Cerebral Ischemia
PROgnostic Value of MicroParticles and Markers of Hemostasis in TIA and Ischemic Stroke
The purpose is to investigate if different microparticles and markers of hemostasis predict outcome after TIA or ischemic stroke and to study the association between these variables and stroke subtype or etiology.
- Conditions
- Brain Ischemia, Cerebral Ischemia, Extracellular Vesicles, Hemostasis
- Trial name
- PROMPTS (NCT05524506)
- Where
- Sweden
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Behcet's Disease, Central Sensitisation
Assessment of Central Sensitization, Neuropathic Pain, Sleep Quality and Daily Life Activities in Behcet's Disease
There are few studies in the literature regarding increased frequency of neuropathic pain and sleep disturbance and decreased quality of life in Behçet's disease.
- Trial name
- NCT03531385
- Testing
- Central sensitisation, Neuropathic pain, Sleep disturbance
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Stroke, Healthy
fNIRS Study of Effort-dependent Brain Activations During Pointing Movements of the Upper Limb in Post-stroke Patients and Healthy Subjects
Background: Following a stroke, as part of neurorehabilitation, the intensity of effort is important to promote neural changes and stimulate motor recovery.
- Trial name
- BIROBONIRS (NCT06116006)
- Testing
- Upper limb pointing movements in 3 experimental conditions
- Where
- France
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Clinique Les Trois Soleils
Stroke, Immobilization
Characterization of Skeletal Muscle Using Magnetic Resonance Elastography (MRE)
The goal of this proposal is two-fold: (1) to further develop and validate a technology, magnetic resonance elastography (MRE), for quantitatively imaging mechanical properties and tension distribution in muscle and (2) to apply…
- Conditions
- Stroke, Immobilization, Myofacial Pain, Hyperthyroid Myopathy
- Trial name
- NCT00588432
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
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