Clinical trials: Disorder of Circulatory System
Diabetic Retinopathy
Comparison of Aurora Fundus Camera With Traditional Camera in Diabetic Retinopathy With Visual Artificial Intelligence
This study aims to compare the effect of Aurora handheld fundus camera with traditional desktop fundus camera in the fundus photography screening of diabetic patients, and to evaluate the effect of artificial intelligence…
- Trial name
- NCT03903042
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Intracerebral Hemorrhage, Cerebral Hemorrhage
High Risk of Death or Disability in Brain Hemorrhage: Role of Spot Sign and Secondary Markers
This study looks at patients with brain hemorrhage to see if a special sign on brain scans, called the "Spot Sign," combined with other scan features, can predict a higher risk of death or disability.
- Conditions
- Intracerebral Hemorrhage, Cerebral Hemorrhage, Stroke, Brain Injuries
- Trial name
- NCT07172542
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier de Gonesse
Stroke
ArmeoSenso - Reward
This study investigates the use of motivating/rewarding features in a computer based arm rehabilitation program. Half of the subjects will take part, besides receiving standard therapy, in a computer based program delivering a…
- Trial name
- NCT02257125
- Testing
- high incentive, low incentive
- Where
- 3 sites in Switzerland
- Volunteers
- 38 people
- Sponsor
- Cereneo AG
Stroke, Ischemic
Quality Control Project of Stroke in Liaoning Province
To reduce the incidence of stroke and standard the treatment of stroke in Liaoning Province, the present study should be conducted.
- Trial name
- NCT03507517
- Volunteers
- 10,000 people
- Sponsor
- Hui-Sheng Chen
Supraventricular Tachycardia
Adenosine Versus Verapamil for Management of Supraventricular Tachycardia Post- Coronary Artery Bypass Grafting
This prospective study was conducted in 268 patients aged from 65-70 years posted for coronary artery bypass grafting. Patients were randomly allocated to either adenosine or verapamil(control) groups.
- Trial name
- NCT04203368
- Testing
- adenosine, verapamil
- Where
- Egypt
- Volunteers
- 268 people
- Sponsor
- Ain Shams University
Stroke
COMbination of Clopidogrel and Aspirin for Prevention of Early REcurrence in Acute Atherothrombotic Stroke
Primary objective: Comparison of efficacy of the combination therapy (clopidogrel plus aspirin) and the aspirin alone (main comparison) to prevent any recurrent ischemic lesion .
- Trial name
- COMPRESS (NCT00814268)
- Testing
- Clopidogrel, Aspirin
- Where
- South Korea
- Volunteers
- 358 people
- Sponsor
- Sanofi
Stroke
Evaluation of the Benefit of the H'Ability Home Device Used in Supervised Self-rehabilitation at Home on the Autonomy of Post-stroke Patients
The goal of this clinical investigation is to evaluate the benefit of the H'Ability Home device used in supervised self-rehabilitation at home on the autonomy of post-stroke patients.
- Trial name
- NCT07202520
- Testing
- IVR : H'Ability Home, Control: paper-based exercise guide
- Where
- 5 sites in France
- Volunteers
- 44 people
- Sponsor
- H'ability
Cardiovascular Complication, Pulmonary Embolism
MACE and PE in Elective Primary TKA & THA
This study ought to identify the occurence of the major adverse cardiovascular events (MACE) and the pumonary emoblism (PE) in patients undergoing elective primary THA \& TKA
- Conditions
- Cardiovascular Complication, Pulmonary Embolism, Stroke, Transient Ischemic Attack
- Trial name
- NCT05116280
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Stroke, Endovascular Thrombectomy
Multidimensional Evaluation of Patients With Acute Ischemic Stroke Undergoing Pharmacological and Endovascular Revascularization Procedures for the Identification of Positive Prognostic Factors
In developed countries, stroke is the third leading cause of death and the leading cause of permanent disability. Systemic and endovascular thrombolytic treatments in acute cerebral ischemic stroke caused by occlusion of large…
- Conditions
- Stroke, Endovascular Thrombectomy, Ischemic Stroke
- Trial name
- NCT05708079
- Testing
- Endovascular thrombectomy
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hypotension, Orthostatic
Study to Assess the Benefit of Midodrine in the Treatment of Patients With Neurogenic Orthostatic Hypotension
The purpose of this clinical study is to evaluate the clinical effect of midodrine hydrochloride (ProAmatine®) compared to placebo in patients with orthostatic hypotension by measuring the time to onset of near syncopal symptoms…
- Trial name
- NCT00555880
- Testing
- Midodrine hydrochloride
- Where
- 11 sites in United States
- Volunteers
- 24 people
- Sponsor
- Shire
Abdominal Aortic Aneurysm
Nectero EAST System Clinical Study
The purpose of this randomized clinical trial is to treat patients with small to mid-sized abdominal aortic aneurysms (AAA), maximum diameter of 3.5 cm to 5.0 cm, using a locally delivered, single-dose endovascular treatment.
- Trial name
- stAAAble (NCT06001918)
- Testing
- Nectero EAST System
- Where
- 42 sites in United States, Australia and 1 more
- Volunteers
- 400 people
- Sponsor
- Nectero Medical, Inc.
COVID-19, Cardiovascular Diseases
The COVID-RASi Trial (COVID-19)
The COVID-RASi study is an international randomized clinical trial that will evaluate the potential benefit of angiotensin modulators on clinical outcomes, in COVID-19 patients.
- Trial name
- NCT04591210
- Testing
- Angiotensin converting enzyme inhibitor, Angiotensin II Receptor Blockers
- Where
- 31 sites in Brazil, Canada and 1 more
- Volunteers
- 372 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Intracranial Atherosclerotic Stenosis (ICAS), Stroke
The New Clinical Registration Trial of Interventional Treatment for Patients with Symptomatic Intracranial Artery Stenosis
Background: Intracranial atherosclerotic stenosis (ICAS) is a major etiology of stroke worldwide, especially in East and South Asia, accounting for up to 50% of all ischemic stroke.
- Trial name
- CRTICAS-2 (NCT06740513)
- Testing
- Endovascular Treatment
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Xuanwu Hospital, Beijing
Cardiovascular Disease
Comprehensive Rimonabant Evaluation Study of Cardiovascular ENDpoints and Outcomes
The primary objective is to show whether rimonabant reduces the risk of a heart attack (MI), stroke, or death from an MI or stroke in patients with abdominal obesity with other cardiovascular (CV) risk factors.
- Trial name
- CRESCENDO (NCT00263042)
- Testing
- Rimonabant
- Where
- 43 sites in United States, Argentina and 41 more
- Volunteers
- 18,695 people
- Sponsor
- Sanofi
Multiple Myeloma
Pharmacokinetic Study of Thalidomide in Subjects With Multiple Myeloma
Objective of this study is to characterize the steady-state pharmacokinetics (PK) of thalidomide when given orally as monotherapy to subjects with multiple myeloma.
- Trial name
- NCT01937442
- Testing
- Thalidomide Celgene™
- Where
- 7 sites in France, United Kingdom
- Volunteers
- 7 people
- Sponsor
- Celgene
Diabetes, STEMI
Sweetheart-Register: Risk Management of Diabetics with Acute Myocardial Infarction
The Sweetheart register (Risk management of Diabetics with acute myocardial infarction) documents both the prevalence of pathologic glucose metabolism in consecutive high-risk patients with STEMI and NSTEMI in daily hospital…
- Conditions
- Diabetes, STEMI, NSTEMI, Myocardial Infarction
- Trial name
- Sweetheart (NCT01197742)
- Where
- 2 sites in Germany
- Volunteers
- 2,772 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Acute Stroke
Investigation of the Reliability and Validity of the Movement Imagination Questionnaire - Revised Second in Acute Stroke Patients
Our study was planned to investigate the reliability validity of the Movement Imagery Questionnaire- RS in acute stroke patients.
- Trial name
- NCT04283760
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Neuroendocrine Neoplasm, Neuroendocrine Neoplasm of Gastrointestinal Tract
Genetic Bases of Neuroendocrine Neoplasms in Mexican Patients
Neuroendocrine neoplasms (NENs) are a heterogeneous group of lesions derived from cells with the ability to produce hormones that may arise from multiple different organs.
- Conditions
- Neuroendocrine Neoplasm, Neuroendocrine Neoplasm of Gastrointestinal Tract, Neuroendocrine Neoplasm of Lung, Thymic Neuroendocrine Neoplasm
- Trial name
- NCT06523582
- Where
- 3 sites in Mexico
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Ventricular Arrhythmia, Acute Myocardial Infarction (AMI)
Ventricular Arrhythmias in Acute Myocardial Infarction
Ventricular arrhythmias are a serious complication of myocardial infarction. The aim of this study is to provide reliable data on the management and mortality associated with ventricular arrhythmia in the setting of acute…
- Trial name
- ADVERSE-MI (NCT07517523)
- Where
- 8 sites in France
- Volunteers
- 500 people
- Sponsor
- Poitiers University Hospital
Type 2 Diabetes
An Observational Study to Assess the Prevalence of Heart Failure in Type 2 Diabetes Patients
An Observational Study to assess the Prevalence of Heart Failure in Type 2 Diabetes Patients in India.
- Trial name
- HF-Registry (NCT04072523)
- Where
- 26 sites in India
- Volunteers
- 621 people
- Sponsor
- AstraZeneca
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