Clinical trials: Disorder of Circulatory System
Primary Aldosteronism, Hypertension
Adrenal Artery Ablation for Primary Aldosteronism
Primary aldosteronism (PA) is one of the most common causes of endocrine and resistant hypertension. Current studies have shown that the activation of the renin-angiotensin-aldosterone system (RAAS) and the increased sympathetic…
- Trial name
- NCT03653845
- Testing
- Endovascular chemical Ablation of Adrenal Gland, Sequenced antihypertensvie drugs with titrated dosage
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Third Military Medical University
Atrial Fibrillation
Cerebral Embolism (CE) in Catheter Ablation of Atrial Fibrillation (AF)
Radiofrequency catheter ablation of atrial fibrillation (AF) induces a procoagulant state, which leads to an acute risk for symptomatic cerebral embolism (CE) of approximately 1%.
- Trial name
- CE-AF (NCT01361295)
- Testing
- PVI with PVAC gold, PVI with Cooled-RF
- Where
- Netherlands
- Volunteers
- 70 people
- Sponsor
- Serge A. Trines
Stroke
Spanish Version of the Brief-BESTest in Stroke Patients
The aim of this study is to adapt and validate the Spanish version of the Brief-BESTest in stroke patients
- Trial name
- NCT04673539
- Testing
- Spanish version of the Brief-BESTest in stroke patients
- Where
- Spain
- Volunteers
- 44 people
- Sponsor
- University of Salamanca
Multiple Myeloma
Postmarketing Study of Empliciti in Korean Patients With Multiple Myeloma
This study is a regulatory postmarketing surveillance study for Empliciti with a representative sample of the overall Korean multiple myeloma (MM) population.
- Trial name
- NCT03660072
- Testing
- Non-Interventional
- Where
- South Korea
- Sponsor
- Bristol-Myers Squibb
Non-valvular Atrial Fibrillation
WAVECREST Post Market Clinical Follow-Up (PMCF) Study
The WAVECREST PMCF Study is a prospective, non-randomized, multicenter study to confirm safety and performance of the Coherex WaveCrest Left Atrial Appendage (LAA) Occlusion System in the current medical practice setting in…
- Trial name
- NCT03204695
- Testing
- Percutaneous LAA Closure, Anticoagulation or Clopidogrel
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- Coherex Medical
Aortic Valve Replacement, Aortic Stenosis
TAVI Protocol - Paravertebral Block Study
Trans-apical aortic valve replacement is a new treatment for severe aortic stenosis. It is offered to elderly patients with medical problems that would markedly increase the risk of conventional cardiac surgery.
- Trial name
- TAVI PVB (NCT01404975)
- Testing
- Thoracic paravertebral block (PVB)
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University Health Network, Toronto
Nephropathy, Cardiovascular Diseases
The Effects of Atorvastatin on the Nitrogen Oxide-system in Patients With Type 2 Diabetes and Nephropathy
It has been documented that statin reduce mortality and morbidity in patients with cardiovascular disease. This effect can partly be related to a reduction in cholesterol levels in blood.
- Conditions
- Nephropathy, Cardiovascular Diseases, Diabetes Mellitus
- Trial name
- STAD (NCT01208701)
- Testing
- Atorvastatin, Unikalk
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- Erling Bjerregaard Pedersen
Insufficiency;Cardiac, Cancer
Effect of Physical Training in Patients With Heart Failure Caused by Chemotherapy for Cancer Treatment
New therapies for cancer increased patient survival, but led to the recognition of adverse effects associated with cancer treatment, such as the use of chemotherapy.
- Conditions
- Insufficiency;Cardiac, Cancer, Cardiotoxicity, Heart Failure
- Trial name
- NCT04047901
- Testing
- exercise training
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke
Kinesio Taping Along With Functional Activation Pattern in Stroke Patients
In stroke; gait deviation occurs usually due to weakness in the tibialis anterior and over activation/spasticity of planter flexors.
- Trial name
- NCT05425212
- Testing
- Functional activation with kinesio tapping, Conventional physical therapy
- Where
- Pakistan
- Volunteers
- 16 people
- Sponsor
- Riphah International University
Stroke
Effect of Segmental Muscle Vibration on Upper Limb Function in Post Stroke Patients
The aim of this study is to observe and to compare effects of segmental vibration on flexors versus extensor muscle groups on upper limb function in post-stroke patients.
- Trial name
- NCT05356481
- Testing
- segmental muscle vibration
- Where
- 2 sites in Pakistan
- Volunteers
- 57 people
- Sponsor
- Riphah International University
Hypertension, Hypotension
Accuracy of Non-Invasive Blood Pressure Measurement in Adults
The purpose of this study is to compare the accuracy of the Sotera ViSi, an investigational device, to auscultation (measurement with a cuff) in determining systolic and diastolic blood pressure (BP) in adult subjects.
- Trial name
- NIBP (NCT01183741)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sotera Wireless, Inc.
Diabetes Mellitus, Hypertension
Effectiveness of Home-Based Health Messaging for Patients With Hypertension and Diabetes
Patients treated at Veterans Affairs (VA) medical centers are older and have multiple chronic conditions. Two of the most common conditions in the VA population are hypertension (HTN) and Type 2 diabetes (DM).
- Trial name
- NCT00119054
- Testing
- In Home Health Messaging Device
- Where
- United States
- Volunteers
- 302 people
- Sponsor
- US Department of Veterans Affairs
Systemic Lupus Erthematosus (SLE), Lupus Nephritis (LN)
Non Invasive Assessment of Subclinical Atherosclerosis and Cardiovascular Risk Using TYG Index in Lupus Nephritis
Systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune disease characterized by loss of immune tolerance, autoantibody production, immune complex deposition, and complement activation, resulting in widespread…
- Trial name
- NCT07719322
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- Assiut University
Stroke, Impairment Upper Limb
Therapy to Improve Reaching Movement in Upper Limb
Strokes are caused by a bleed in the brain and can be life threatening. One common consequence is upper limb impairment. This causes stroke patients to be unable to use their arms and upper body to do simple tasks such as…
- Trial name
- NCT03508037
- Testing
- Neuromodulation electroencephalographic signals and functional electrical stimulation based
- Where
- Spain
- Volunteers
- 16 people
- Sponsor
- Cajal Institute of the Spanish National Research Council
Stroke
The Effect of Home-Based Telerehabilitation in Individuals With Stroke
Stroke is a clinical picture that develops due to occlusion or rupture of cerebral vessels and results in loss of cerebral functions.
- Trial name
- NCT05083195
- Testing
- Home-based Telerehabilitation, Exercise Brochure
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University - Cerrahpasa
Gastric Antral Vascular Ectasia
Endoscopic Band Ligation Versus Argon Plasma Coagulation for the Treatment of Gastric Antral Vascular Ectasia: a Randomized Clinical Trial
The investigators goal is to compare the standard argon plasma coagulation (APC) treatment with endoscopic band ligation (EBL) in patients with Gastric Antral Vascular Ectasia.
- Trial name
- NCT01601639
- Testing
- Endoscopic Band Ligation, Argon plasma Coagulation (APC) for GAVE
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of Alberta
Acute Ischemic Stroke
Evaluation of the Safety and Efficacy of Hemacord HPC, Cord Blood in Subjects With Acute Ischemic Stroke
This is a phase one study investigating the safety and efficacy profile of allogeneic cord blood hematopoietic progenitor cells (HPC, Cord Blood), when administered by intravenous infusion and intrathecal injection, in subjects…
- Trial name
- NCT03735277
- Testing
- HPC, Cord Blood
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- BHI Therapeutic Sciences
Multiple Myeloma
2006-32 Phase II Study of Rapidly Recycled High Dose DTPACE
This study is being done in an attempt to improve the remission rate and the survival time for subjects with high-risk myeloma. It is hoped that by giving higher doses of commonly used chemotherapy drugs and by giving courses…
- Trial name
- NCT00577512
- Testing
- DTPACE
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Arkansas
Chromosome 13 Aneuploidy, Chromosome 18 Aneuploidy
Non-invasive Prenatal Diagnostic Validation Study
The primary purpose of this study is to collect maternal blood samples from pregnant women to develop a non-invasive prenatal diagnostic test based on fetal DNA isolated from maternal blood.
- Conditions
- Chromosome 13 Aneuploidy, Chromosome 18 Aneuploidy, Chromosome 21 Aneuploidy, Sex Chromosome Aberrations
- Trial name
- NIPD (NCT01574781)
- Testing
- Blood draw, Cheek swab/Saliva Sampling
- Where
- United States
- Volunteers
- 1,781 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
Coronary Artery Disease, High Bleeding Risk Patients
ULTRA LONG: BioFreedom Ultra
The goal of this Prospective, multi-center, open-label single-arm study is to Assess the Safety and Effectiveness of additional sizes of the BioFreedom Ultra CoCr Biolimus A9 coated coronary stent system in Patients at high risk…
- Trial name
- NCT05643430
- Testing
- BioFreedom Ultra
- Where
- 9 sites in France, United Kingdom
- Volunteers
- 86 people
- Sponsor
- Biosensors Europe SA
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