Clinical trials: Disorder of Endocrine Ovary
Polycystic Ovary Syndrome
Auricular Acupressure (AA) For Overweight/Obese Adolescent and Young Polycystic Ovary Syndrome ( PCOS)
The purpose of this trial is to investigate the effect and safety of auricular acupressure on adolescent and young women with PCOS.
- Trial name
- NCT02326714
- Testing
- Auricular acupressure
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Heilongjiang University of Chinese Medicine
Polycystic Ovary Syndrome, Overweight and Obesity
Lifestyle Intervention in Pregnant Women With PCOS
Polycystic ovarian syndrome (PCOS) is the most common reproductive disorder in women of childbearing age and is also associated with metabolic abnormalities including obesity, type 2 diabetes, dyslipidemia, etc.
- Conditions
- Polycystic Ovary Syndrome, Overweight and Obesity, Gestational Diabetes
- Trial name
- NCT04216485
- Testing
- Intensive Lifestyle Intervention, Standard Care
- Where
- China
- Volunteers
- 296 people
- Sponsor
- Capital Medical University
PCOS (Polycystic Ovary Syndrome)
Impact of Myo-Inositol Alone vs Myo-Inositol Plus Metformin on Conception, Adherence, and Tolerability in PCOS
The goal of this clinical trial (prospective randomized controlled trial) is to compare whether myo-inositol alone or in combination with metformin can improve conception rates, treatment compliance, and side-effect profiles in…
- Trial name
- NCT07323589
- Testing
- Myoinositol, Metformin 1500 mg daily
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- PAEC general hospital
Polycystic Ovarian Syndrome, Subfertility
Comparison Between the Role of Follicular Output Rate and Preovulatory Count in the Prediction of Pregnancy in Women With Polycystic Ovarian Syndrome Undergoing Intra Cytoplasmic Sperm Injection (ICSI)
Our study is observational, we are observing data from routine measurements during IVF/ICSI. Our study does not assess IVF/ICSI as an intervention, we are evaluating the role of FSI and preovulatory count which are calculated by…
- Conditions
- Polycystic Ovarian Syndrome, Subfertility, ICSI
- Trial name
- NCT02190006
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Effect of Laser Puncture Versus Ultraviolet Radiation on Women With Polycystic Ovarian Syndrome
Obese women with polycystic ovarian syndrome aged between 25 and 35 years old will be divided into three groups. For three months, group (A) will receive laser puncture (3 sessions per week), along with a metformin…
- Trial name
- NCT05986838
- Testing
- aser puncture, ultraviolet radiatio, Metformin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Polycystic Ovarian Syndrome
In-Vitro Maturation of Oocytes From Polycystic Ovarian Patients Undergoing IVF
Retrieval of immature oocytes from women with polycystic ovaries, their in-vitro maturation, fertilization and embryo transfer can prevent hormonal treatment that can lead to ovarian hyperstimulation.
- Trial name
- IVM (NCT00561808)
- Testing
- In-vitro maturation oocytes
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Quality of Life
Polycystic Ovary Syndrome and Education
Aim: This research is being designed to determine the effect of Polycystic Ovary Syndrome (PCOS) education given to women on their quality of life.
- Trial name
- NCT06401850
- Testing
- Education Group, Control Group
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Marmara University
Polycystic Ovary Syndrome, Diabetes, Gestational
Metformin for Prevention Gestational Diabetes in Pregnant Women With Polycystic Ovarian Syndrome
Randomized, placebo controlled clinical trial that evaluate the role of taking metformin therapy during pregnancy in women with polycystic ovarian syndrome(PCOS) in reducing the development of gestational diabetes(GDM) and…
- Trial name
- MGDPCOS (NCT02802215)
- Testing
- metformin
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Ain Shams University
Polycystic Ovary Syndrome
Effect of Magnesium Supplementation on Polycystic Ovary Syndrome
This is a double-blind randomized clinical trial which will start at June 2014 and end on June 2015 in Isfahan city. Serum insulin level is considered as a key variable and the sample size calculated 70 persons (35 persons for…
- Trial name
- NCT02178150
- Testing
- Magnesium Oxide
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Polycystic Ovary, Progesterone Resistance
Progesterone Action on Endometrium of PCOS
Objective: To study the influence of metabolic factors on the action of progesterone on the endometrium of women with PCOS. Design: A prospective open-label clinical trial.
- Trial name
- NCT05062135
- Testing
- Progesterone 400 Mg Vaginal Suppository on PCOS
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Polycystic Ovarian Syndrome (PCOS), Oxidative Stress
Oxidative Stress in Polycystic Ovary Syndrome
The aim of the study was to determine changes in hematological and biochemical parameters and specific oxidative stress markers in patients with PCOS.
- Trial name
- NCT06826625
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Mardin Artuklu University
Obesity, Polycystic Ovary Syndrome
Treatment of Obesity With Topiramate in Patients With Polycystic Ovary Syndrome
Treatment of obesity related to Polycystic Ovary Syndrome with topiramate or placebo to assess improvement of clinical and laboratory parameters after 6 months of follow-up
- Conditions
- Obesity, Polycystic Ovary Syndrome, Hyperandrogenism
- Trial name
- NCT04453306
- Testing
- Topiramate
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Polycystic Ovarian Syndrome (PCOS)
Comparative Study Between HOMA1-IR and HOMA2-IR in Prediction of Ovulation Outcome in Women With PCOS
122 women diagnosed with PCOS seeking fertility in the fertility clinic at kasr Alainy hospital will be subjected to Homeostatic model assessment for insulin resistance 1 was calculated for all participants through the equation…
- Trial name
- NCT06793904
- Testing
- Aromatase inhibitor Letrozole
- Where
- Egypt
- Volunteers
- 122 people
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Prevalence of Polycystic Ovary Syndrome (PCOS) in Obese Premenopausal Women
Between 40% and 85% of women with Polycystic Ovary Syndrome (PCOS) are overweight or obese and obesity is closely linked to the development of PCOS.
- Trial name
- NCT01319162
- Testing
- Weight reduction regimen
- Where
- Sweden
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Polycystic Ovary Syndrome
Efficacy of Jianpi Qushi Huatan Decoction in the Treatment of Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common reproductive disease associated with endocrine and metabolic disorders. Some studies have shown that Chinese herbal medicine is beneficial for PCOS, but the efficacy of Chinese herbal…
- Trial name
- NCT05976295
- Testing
- Jianpi Qushi Huatan Decoction
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Polycystic Ovary Syndrome
Effect of Low-frequency Electroacupuncture (EA) on Polycystic Ovary Syndrome
Low-frequency electroacupuncture (EA) can decrease serum 17-hydroxyprogesterone (17-OHP), androstenedione (A) and testosterone (T)of young women with polycystic ovary syndrome in the Human chorionic gonadotrophin (HCG)…
- Trial name
- NCT01812161
- Testing
- acupuncture protocol 1, Acupuncture protocol 2
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Huazhong University of Science and Technology
Polycystic Ovary Syndrome, Chronic Periodontitis
Chronic Periodontitis and Polycystic Ovary Syndrome
Background: The aim of this study was to investigate the levels of malondialdehyde (MDA), total antioxidant status (TAS), 8-hydroxy-2´- deoxyguanosine (8-OHdG) in blood serum and saliva samples in female patients with chronic…
- Trial name
- NCT02954120
- Testing
- no intervention provided
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Gene Abnormality
Endometrial Heparin-binding Epidermal Growth Factor Expression
Women with PCOS comprise a majority of fertility clinic attendees. Unfortunately, a high failure rate following fertility treatment was observed especially in obese women due to implantation failure.
- Trial name
- NCT04175002
- Testing
- utrogestan
- Where
- Malaysia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Ovarian Neoplasms, Endometrial Neoplasms
A Study of PF-07260437 in Advanced or Metastatic Solid Tumors
A study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and antitumor activity of PF-07260437, a B7-H4 x CD3 bispecific mAb, in participants aged ≥18 years of age with advanced or metastatic…
- Conditions
- Ovarian Neoplasms, Endometrial Neoplasms, Breast Neoplasms
- Trial name
- C4431001 (NCT05067972)
- Testing
- PF-07260437, B7-H4 IHC
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- Pfizer
Polycystic Ovarian Syndrome (PCOS)
This Study Aims to Evaluate Whether Milamend's Product Could Improve Hormone Balance in Women Who Suffer From Self-reported PCOS Symptoms.
The rationale for this study is to observe the impact of a consumer-grade commercially available product called Milamend Hormone Balance on quality of life and hormonal health in women with self-reported symptoms associated with…
- Trial name
- NCT07764328
- Testing
- A dietary supplement powder for women
- Where
- United States
- Volunteers
- 225 people
- Sponsor
- Mila Mend Inc.