Clinical trials: Disorder of Hip Joint
Osteoarthritis
Efficacy of Intravenous Versus Topical Tranexamic Acid in Primary Total Hip Arthroplasty
Bleeding during and after total hip replacement surgery is a primary concern to the surgical and anaesthetic team. Tranexamic acid is a commonly-used drug that helps blood clotting and decreases surgical bleeding.
- Trial name
- TeACH-R (NCT02056444)
- Testing
- Tranexamic Acid
- Where
- Canada
- Volunteers
- 149 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Rheumatoid Arthritis, Osteoarthritis
A Multi-centre Study to Assess the Long-term Performance of the DePuy ASR™ System in Primary Hip Resurfacing Surgery
The purpose of this study is to monitor the performance and determine the metal ion release of the DePuy ASR™ System in the treatment of patients with hip joint disease requiring hip resurfacing surgery.
- Conditions
- Rheumatoid Arthritis, Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders
- Trial name
- NCT00208377
- Testing
- DePuy ASR Hip System
- Where
- 3 sites in Australia, Germany and 1 more
- Volunteers
- 228 people
- Sponsor
- DePuy International
Developmental Dysplasia of the Hip
AI-assisted Preoperative Planning Technology for THA for DDH
In this study, the investigators retrospectively collected DDH case data of THA assisted by AI 3D planning and THA assisted by traditional planning.
- Trial name
- NCT05929105
- Testing
- artificial intelligence (AI)-assisted three-dimensional preoperative planning technology, X-ray film template for 2D planning
- Where
- China
- Volunteers
- 61 people
- Sponsor
- General Hospital of Ningxia Medical University
Osteolysis, Arthroplasty Complications
Plasmafit® Revision Structan® Hip Endoprosthesis Cup
The aim of this observational study is to collect clinical and radiological results of the new Plasmafit® Revision Structan® Hip Endoprosthesis Cup in a standard patient population and when used in routine clinical practice.
- Conditions
- Osteolysis, Arthroplasty Complications, Instability of Prosthetic Joint, Degenerative Osteoarthritis
- Trial name
- NCT04255966
- Testing
- Plasmafit® Revision Structan®
- Where
- 4 sites in Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG
Osteoarthritis
Tanezumab In Osteoarthritis Of The Hip Or Knee
The purpose of the study is to test the efficacy and safety of 2 doses of tanezumab compared to oxycodone CR and placebo in patients with osteoarthritis
- Trial name
- NCT00985621
- Testing
- tanezumab 10 mg, tanezumab 5 mg, oxycodone
- Where
- 112 sites in United States, Austria and 5 more
- Volunteers
- 614 people
- Sponsor
- Pfizer
Hip Osteoarthritis
Clinical Effects of Translatoric Grades of Movement in Hip Osteoarthritis Patients
In orthopaedic manual therapy translatoric grades of movement are used to determine the intensity of force applied during the mobilization.
- Trial name
- NCT02498314
- Testing
- Grade I-II SZ mobilization, Grade II TZ mobilization, Grade III mobilization
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Zaragoza
Osteoarthritis, Post-traumatic Arthritis
A Randomised Study to Compare Metal Ion Release and Long-term Performance of the Pinnacle™ Cup With a Ceramic-on-Metal or a Metal-on-Metal Bearing
The purpose of this study is to monitor the performance and compare the metal ion release of two bearing combinations, ceramic-on-metal and metal-on-metal in the treatment of patients with hip joint disease requiring a total hip…
- Conditions
- Osteoarthritis, Post-traumatic Arthritis, Collagen Disorders, Avascular Necrosis
- Trial name
- NCT00873444
- Testing
- Pinnacle™ Acetabular System
- Where
- Germany
- Volunteers
- 5 people
- Sponsor
- DePuy International
Coxarthrosis, Fracture of Femoral Neck
Zink and Bone Strength
Zink and bone strength
- Trial name
- NCT00317863
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Degenerative Osteoarthritis
A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis
A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Determine the Efficacy, Safety, and Dosing of TG-C in Adult Subjects with Symptomatic Early Hip Osteoarthritis.
- Trial name
- NCT05276011
- Testing
- TG-C
- Volunteers
- 255 people
- Sponsor
- Kolon TissueGene, Inc.
Hip Osteoarthritis, Hip Pain Chronic
Fast Track Total Hip Arthroplasty vs Standard Care
Fast-track total hip arthroplasty (THA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-H (NCT04211987)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoarthritis, Hip
Comparison of Clinical Results of Two Cementless Femoral Stem
In the present study, two types of cementless femoral stem- UTS Stem and UTF-reduced Stem- were utilized in total hip arthroplasty.
- Trial name
- NCT04501185
- Testing
- total hip arthroplasty
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Hip Dysplasia
Exercise and Patient Education Compared With Usual Care in Patients With Hip Dysplasia
This effectiveness trial will investigate if patients with hip dysplasia randomised to exercise and patient education have a different mean change in self-reported pain measured by the Copenhagen Hip and Groin Outcome Score…
- Trial name
- MovetheHip (NCT04795843)
- Testing
- Exercise and patient education, Usual Care
- Where
- 2 sites in Denmark
- Volunteers
- 200 people
- Sponsor
- University of Aarhus
Degenerative Joint Disease
R3 Delta Ceramic Acetabular System PAS U.S.
R3 Delta Post-Approval Study U.S.
- Trial name
- R3-PAS (NCT03056534)
- Testing
- R3 Biolox Delta Ceramic Acetabular System
- Where
- 8 sites in United States
- Volunteers
- 189 people
- Sponsor
- Smith & Nephew, Inc.
Cerebral Palsy (CP)
The Effect of Hip Joint Orthotic Intervention and Conventional Exercise Training on Spasticity, Balance and Walking Performance in Children With Cerebral Palsy
Cerebral palsy (SP) is defined as a group of persistent disorders that cause activity limitation of movement and postural development. Children with cerebral palsy are typically born with a normal anatomical hip sequence.
- Trial name
- NCT07000578
- Where
- Turkey (Türkiye)
- Volunteers
- 19 people
- Sponsor
- Medipol University
Osteoarthritis Hip, Joint Disease
Mobilization With Movement in Patients With Osteoarthritis of the Hip
The concept of mobilization with movement, also referred to as a Mulligan mobilization, has not been studied in patients with hip osteoarthritis, subsisting questions about the possible effects in this population.
- Conditions
- Osteoarthritis Hip, Joint Disease, Musculoskeletal Diseases, Pathologic Processes
- Trial name
- MWM (NCT02390336)
- Testing
- Real mobilization-with-movement (MWM)
- Volunteers
- 40 people
- Sponsor
- Natália Maria Oliveira Campelo
Developmental Dysplasia of Hip
Evaluation of the Effectiveness of Developmental Hip Dysplasia Screening in Risk Groups
This study is a non-drug clinical trial. Developmental dysplasia of the hip (DDH) encompasses a spectrum of hip developmental disorders, including dislocation, subluxation, and acetabular dysplasia.
- Trial name
- NCT07066852
- Testing
- x ray, ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Developmental Dysplasia of the Hip (DDH)
Universal Ultrasound-screening for Developmental Dysplasia of the Hip in Newborn
All newborn from the period 12.1988 to 31.12.2006 During the two last decades, hip ultrasound has gained acceptance as an accurate screening test for developmental dysplasia of the hip (DDH) and for monitoring the development and…
- Trial name
- NCT01053299
- Testing
- open, prospective cohort-study
- Where
- Norway
- Volunteers
- 4,200 people, healthy volunteers welcome
- Sponsor
- Vestre VikenHF Kongsberg Sykehus
Osteoarthritis, Pain
Study of Safety, Efficacy of Fulranumab Adjunctive Use in OA of Hip or Knee, PAI3007
The purpose of this study is to demonstrate the efficacy, safety, and tolerability of fulranumab as adjunctive therapy compared with placebo in participants with signs and symptoms of osteoarthritis of the hip or knee that are…
- Trial name
- NCT02301234
- Testing
- Fulranumab 1 mg, Fulranumab 3 mg, Celecoxib 100 mg
- Where
- 64 sites in United States, Australia and 9 more
- Volunteers
- 111 people
- Sponsor
- Janssen Research & Development, LLC
Hip Arthroplasty, Knee Arthroplasty
Effect of Combined Use of Naloxone and Tramacet on Postop Analgesia in Elderly Patients Having Joint Replacement Surgery
Patients over 70 years of age, scheduled for joint replacement surgery will be randomized to tramacet/ naloxone plus morphine PCA or to morphine PCA to assess quality of analgesia in the postoperative period.
- Conditions
- Hip Arthroplasty, Knee Arthroplasty, Spinal Anesthesia
- Trial name
- NCT00679614
- Testing
- tramacet, naloxone, tramacet, Acetaminophen
- Where
- Canada
- Volunteers
- 45 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Osteoarthritis
Systemic Effects of Chronic Metal Ion Exposure From Metal-on Metal Hip Resurfacing
In recent years hip resurfacing has become a very popular alternative treatment to total hip replacement for the treatment of hip arthritis.
- Trial name
- Metal Ions (NCT01493141)
- Where
- United Kingdom
- Volunteers
- 46 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
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