Clinical trials: Disorder of Tooth Development
Molar Incisor Hypomineralization
Educational Program to Improve Dental Interns, Knowledge ,Attitude and Awareness Toward Molar Incisor Hypo-mineralization.
This interventional, quasi experimental study aims to assess the effectiveness of an educational program on improving dental interns' knowledge, attitude and awareness regarding Molar-Incisor Hypo-mineralization (MIH).
- Trial name
- MIH (NCT07129720)
- Testing
- Educational Program on MIH
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Mouthwashes, Chlorhexidine
Effects of Two Daily CHX Mouthrinses on Plaque, Gingivitis and Staining
Τhe aim of this randomized clinical trial was to investigate the efficacy of two daily mouth rinses containing CHX and different combinations of H2O2 and CPC, when used adjunctive to mechanical oral hygiene, and compare them with…
- Conditions
- Mouthwashes, Chlorhexidine, Dental Plaque, Gingival and Periodontal Disease
- Trial name
- NCT07351370
- Testing
- chlorhexidine/ cetylpyridinium chloride/ hydrogen peroxide mouthwash, Chlorhexidine/ cetylpyridinium chloride
- Where
- Greece
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Dental School
Molar Incisor Hypomineralization
Association Between Molar-Incisor Hypomineralization, Maternal Stress and Anxiety: A Cross-Sectional Study.
This study aims to evaluate the association between Molar-Incisor Hypomineralization, Maternal Stress and anxiety in a group of pediatric patients.
- Trial name
- NCT06081491
- Testing
- diagnosis
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Cairo University
Molar-Incisor Hypomineralization, Peridontal Disease
Molar-Incisor Hypomineralization Vs Periodontal Health
Background: To investigate the effect of molar incisor hypomineralization (MIH) on periodontal health, to evaluate the relationship between gingival crevicular fluid (GCF) volume, and GCF biomarkers such as matrix…
- Trial name
- MIH (NCT06764043)
- Testing
- Clinical evaluation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Vitamin D Deficiency, Dental Caries
Maternal Vitamin D Levels in Pregnancy and Dental Caries in Children
The main aim of this study is to investigate potential associations between maternal pre- and postnatal vitamin D level and oral health outcomes (caries and developmental defects of enamel) in their children at 7-9 years of age.
- Conditions
- Vitamin D Deficiency, Dental Caries, Dental Enamel Hypoplasia
- Trial name
- NCT03273725
- Testing
- Dental examination including taking a saliva sample.
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- Tannhelsetjenestens Kompetansesenter Midt-Norge
Dental Erosion
Effect of Smoking on Saliva Composition and the Development of Dental Erosion
The aim of this study is to investigate whether smoking is associated with changes in salivary composition and/or predisposition to erosion.
- Trial name
- NCT04208802
- Testing
- Use of fluoridated toothpaste, Wearing of an intraoral device with bovine tooth samples, Wearing of an intraoral device with resin samples
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Göttingen
Traumatic Dental Injury, Autism Spectrum Disorder
Occurrence of Traumatic Dental Injury in a Group of Egyptian Autistic Children Compared to Normal Children: (A Cohort Study)
The aim of the study is to assess the occurrence of traumatic dental Injury in a group of Egyptian Autistic Children compared to normal children. Population: Egyptian children Exposure: Autistic children.
- Conditions
- Traumatic Dental Injury, Autism Spectrum Disorder, Dental Trauma
- Trial name
- NCT04235543
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries, Early Childhood Caries
Oral Health and Dental Caries Prevention Intervention for Children in Romania
During 2019-2020, the National Oral Health Survey evaluated a significant sample of children aged 5, 6 and 12 years, gathering baseline data on oral health.
- Conditions
- Dental Caries, Early Childhood Caries, Quality of Life
- Trial name
- Smilebright (NCT06441500)
- Testing
- Daily tooth brushing programme
- Where
- 5 sites in Romania
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy "Victor Babes" Timisoara
Molar Incisor Hypomineralisation
Articaine 4% Versus Lidocaine 2% for Local Anesthesia of MIH-affected Maxillary Molars
Comparison of injection pain with lidocaine and articaine. Comparison of the efficacy of lidocaine and articaine during treatment of MIH- maxillary molars.
- Trial name
- NCT05585112
- Testing
- Lidocaine 2%, Articaine 4%
- Where
- Syria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Latakia University
Molar Hypomineralization
Pulpotomy in Hypominerlized Permanent Molars.
The first permanent molars in children can sometimes develop a condition called molar-incisor hypomineralization (MIH), which affects the strength and quality of the tooth structure.
- Trial name
- NCT07756216
- Testing
- Step wise pulpotomy
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Fluorosis, Dental, Fluorosis
Design of a Multicomponent Intervention to Reduce the Risk of Exposure Fluorine
Introduction Systemic exposure to fluoride is a significant challenge for global public health; this is because although fluoride prevents dental caries, prolonged exposure to high concentrations can cause adverse effects on…
- Trial name
- NCT07359937
- Testing
- multicomponent intervention, Conventional intervention
- Where
- Colombia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Antonio Nariño
Molar-Incisor Hypomineralization
Evaluation of Different Anesthesias in Children With Molar Incisor Hypomineralization
In children with molar-incisor hypomineralization (MIH), insufficient depth of anesthesia can lead to increased anxiety and behavior management problems, which may negatively affect the quality of restorations.
- Trial name
- NCT07268157
- Testing
- Computer-controlled anesthesia device (SleeperOne), Conventional injection technique
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Canan Bayraktar Nahir
Osteogenesis Imperfecta, Rare Bone Disorders
Morphology in Oral Rare Syndromes & Artificial Intelligence for Clinical Diagnosis
MOSAIC aims to determine whether oro-dental morphological anomalies, particularly palatal morphology, associated with rare bone and cartilage diseases can be precisely characterized using 3D digital models analysed through…
- Conditions
- Osteogenesis Imperfecta, Rare Bone Disorders, Hypophosphatemia, X-Linked
- Trial name
- MOSAIC (NCT07666269)
- Testing
- intra-oral 3D optical impression
- Where
- France
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Dental Fluorosis
Presence of Enamel Fluorosis in Libyan Children
Fluorosis is caused by hypomineralization in the enamel due to increased fluoride ingestion during early childhood (Cawson.1, Wong et al. 2, and Sudhir 3).
- Trial name
- NCT03746990
- Volunteers
- 1,935 people, healthy volunteers welcome
- Sponsor
- Ajman University
Dental Fluorosis
Systemic Fluoride Bioavailability From Toothpastes Containing Calcium Carbonate or Silica as Abrasives
The risk of dental fluorosis development is related to the systemic exposure to fluoride during enamel formation. Currently, diet and fluoride toothpastes are the main sources of fluoride to children at the age-risk for fluorosis…
- Trial name
- NCT01571050
- Testing
- Purified water, Fresh MFP/CaCO3 toothpaste, Fresh NaF/SiO2 toothpaste
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Dental Enamel Hypoplasia
Laser Used in the Treatment of Hypomineralized Occlusal Lesions in Teeth Enamel Affected by MIH
Background: Nowadays an increase in the incidence of teeth affected by molar incisor hypomineralisation (MIH) has been observed.
- Trial name
- NCT03614819
- Testing
- Diode laser group, Glass Ionomer Sealing Group
- Where
- Brazil
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Molar Hypomineralization, Dental Restoration Failure of Marginal Integrity
CAD-CAM or Adhesive Approaches for MIH Treatment
Aim: This randomized controlled clinical study aimed to compare direct composite resin restorations and Computer Aided Design-Computer Aided Manufacturing (CAD-CAM) supported inlay or onlay restorations in young permanent molar…
- Trial name
- NCT06456619
- Testing
- Tooth restoration
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Baskent University
Molar Incisor Hypomineralization, Hypersensitivity
Intraosseous vs Infiltration Anesthesia in Molar-Incisor Hypomineralization (MIH) Children
This study aims to compare the effectiveness of intraosseous and infiltration anesthesia techniques administered using a computer-assisted anesthesia device (SleeperOne® 5; Dental HiTec, France) during restorative treatments of…
- Trial name
- MIH (NCT07352813)
- Testing
- Intraosseous anaesthesia using a computerized system, Infiltration anaesthesia using a computerized system
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Molar-Incisor Hypomineralization, Molar-Incisor Hypomineralization (MIH)
Comparison of Computer-Assisted and Conventional Local Anesthesia in Children With Molar-Incisor Hypomineralization
The main questions this study aims to answer are: Does computer-controlled local anesthesia cause less pain and anxiety than conventional local anesthesia in children with molar-incisor hypomineralization (MIH)? Is there a…
- Conditions
- Molar-Incisor Hypomineralization, Molar-Incisor Hypomineralization (MIH), Computer-Controlled Local Anesthesia
- Trial name
- NCT07733011
- Testing
- Computer-Controlled Local Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Marmara University
Molar Incisor Hypomineralization
Clinical Performance of Two Cad-cam Fabricated Ceramic Restoration in Teeth Affected With MIH
This study will be performed to evaluate the clinical performance (Plaque accumulation, fracture of (restoration or tooth), postoperative sensitivity, secondary caries, marginal fit and discoloration) of two CAD/CAM fabricated…
- Trial name
- NCT05434884
- Testing
- occlusal veneer restorations, endocrown restorations
- Where
- Egypt
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University