Clinical trials: Disorder of Tooth Development
Pit and Fissure Sealants, Molar Incisor Hypomineralization
Clinical Evaluation of Two Different Pit and Fissure Sealants
It is planned to include girls and boys between the ages of 6-12 who apply to Başkent University Faculty of Dentistry, Pediatric Dentistry Clinic for routine dental examination.
- Trial name
- NCT06776471
- Testing
- Resin-based flowable filling material
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Baskent University
Autism Spectrum Disorder, Autism
Oral Health Care in Autism Spectrum Disorder
Persons with autism spectrum disorder (ASD) are characterized by impairments in social interactions, speech and communication, restricted patterns of behaviour, and unusual sensory sensitivities.
- Trial name
- CREASED (NCT03830541)
- Testing
- Oral care delivery analysis in participants with ASD
- Volunteers
- 52 people
- Sponsor
- University of Novi Sad
Intellectual Disability, Cerebral Palsy
Oral Health Promotion Among Preschool Children With Special Needs
Establishing good oral health-related habit is challenging among younger children, especially for preschool children with special needs, as they have physical, mental, sensory, behavioural, emotional, and chronic medical…
- Conditions
- Intellectual Disability, Cerebral Palsy, Developmental Disorders, Developmental Delay
- Trial name
- NCT03522337
- Testing
- Visual pedagogy (social stories), Conventional leaflets
- Where
- China
- Volunteers
- 306 people
- Sponsor
- The University of Hong Kong
Craniosynostosis, Anesthesia
Influence of General Anesthesia on the Dynamic Changes in Brain Damage Markers During and After Craniosynostosis Operations in Infancy
The issue of anesthetics neurotoxicity is one of the most discussed topics in pediatric anesthesiology, thus it opens the question of the safety of commonly used anesthetics in the pediatric patient.
- Trial name
- TAnBrainDam (NCT05911139)
- Where
- Slovakia
- Volunteers
- 45 people
- Sponsor
- Comenius University
Dentin Sensitivity, Molar Incisor Hypomineralization
Control of Pain Due to Dentin Hypersensitivity in Individuals With Molar-incisor Hypomineralization
Background: Dentin hypersensitivity (DH) is defined as high sensitivity of the vital dentin when exposed to thermal, chemical or tactile stimuli.
- Trial name
- NCT04407702
- Testing
- Hygiene Instructions, Sealant application, Low-level Laser
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Molar-Incisor Hypomineralization (MIH), Masticatory Performance
Evaluation of Occlusal Force and Masticatory Function in Children With Molar-Incisor Hypomineralization
This study aims to evaluate right-left chewing balance and masticatory function in children with Molar-Incisor Hypomineralization (MIH) before and after restorative treatment.
- Conditions
- Molar-Incisor Hypomineralization (MIH), Masticatory Performance, Occlusal Analysis, Chewing Function
- Trial name
- NCT07589179
- Testing
- Glass Hybrid Restorative Treatment
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Marmara University
Molar Incisor Hypomineralization
The Effect of Molar Incisor Hypomineralisation on the Stomatognathic System
This study aims to examine whether children with Molar Incisor Hypomineralization (MIH) are more likely to have problems with the jaw joint and chewing muscles.
- Trial name
- NCT06951139
- Testing
- Ultrasound and Shear Wave Elastography
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ozge Gungor
Molar Incisor Hypomineralization
Digital Intraosseous Anesthesia in MIH-Affected Permanent Molars
This multicentre, randomized clinical trial compared digital intraosseous anaesthesia with conventional local anaesthetic techniques in children aged 6-12 years receiving restorative treatment for MIH-affected permanent first…
- Trial name
- DIA-MIH (NCT07736677)
- Testing
- SleeperOne 5 Computer-Controlled Intraosseous Anaesthesia System, Conventional Maxillary Infiltration Anaesthesia, Conventional Inferior Alveolar Nerve Block Anaesthesia
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Ege University
Molar Incisor Hypomineralization
Local Anesthesia in Molar Teeth With Molar Incisor Hypomineralization
To compare responses to electrical pulp test (EPT) and cold test among molar incisor hypomineralization (MIH)-effected and not MIH-effected carious teeth before and after administration of local anesthesia for caries removal.
- Trial name
- NCT04061096
- Testing
- Evaluation of cold test, Evaluation of electrical pulp test, Evaluation of pain during the treatment
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Didem Sakaryali
Alveolar Bone Loss
Pontic Site Development Using Soft Tissue Augmentation
in patients with vertical or horizontal defective of there ridge it is difficult to have prosthetic restoration with natural appearance emetating and simulating the adjacent abutment emergence profile so this study aims to…
- Trial name
- NCT03834649
- Testing
- partially de-epithelized connective tissue graft, Mucograft
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Nouran Abdulla Mater,MD
Molar Incisor Hypomineralisation
Effect of Nano Hydroxy Apatite Varnish and Potassium Nitrate Gel on the MIH-affected Permanent Teeth
This clinical study main goal is to investigate the effectiveness of nano hydroxy apatite crystal varnish and potassium nitrate gel as a non invasive approach in managing MIH-affected teeth.
- Trial name
- NCT06896565
- Testing
- nano hydroxy apatite varnish, Potassium Nitrate Gel, Varnishes, Fluoride
- Volunteers
- 48 people
- Sponsor
- Cairo University
Hypomineralization of Enamel
PMCs as a Treatment of Children With HSPM Using the HT
Hypomineralised primary second molars are primary molars with a developmental disorder of the enamel. Preformed metal crowns already have good results for the treatment of caries on primary molars.
- Trial name
- NCT04265183
- Testing
- Placing preformed metal crowns using Hall technique.
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Molar Incisor Hypomineralization
Prevalence of MIH Among Group of Egyptians Children Aged From 8 to 12 in Damietta
Assesment of the prevalence of molar incisor hypomineralization among a group of egyptian children aged from 8 to 12 years old in Damietta governate.
- Trial name
- NCT04410172
- Testing
- Mirror and prope
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Eman Zakaria Ali Hashem
Molar Incisor Hypomineralisation, Molar Incisor Hypomineralization
Prevalence of Hypomineralized Second Primary Molars and Its Association with Molar-Incisor Hypomineralization.
The aim for thid study is to detect the prevalence of HSPM and the possible association between MIH and HSPM in a group of Egyptian children aged from 6-12 years.
- Conditions
- Molar Incisor Hypomineralisation, Molar Incisor Hypomineralization, Hypomineralization Molar Incisor, Hypomineralization of Enamel
- Trial name
- NCT06727539
- Volunteers
- 825 people
- Sponsor
- Cairo University
Molar Incisor Hypomineralization
Educational Program to Improve Dental Interns, Knowledge ,Attitude and Awareness Toward Molar Incisor Hypo-mineralization.
This interventional, quasi experimental study aims to assess the effectiveness of an educational program on improving dental interns' knowledge, attitude and awareness regarding Molar-Incisor Hypo-mineralization (MIH).
- Trial name
- MIH (NCT07129720)
- Testing
- Educational Program on MIH
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Children, Adult, Molar Incisor Hypomineralization
Effectiveness of Infiltration With Resin in Treatment of MIH Incisors in Children Showing Opacities
Enamel development defects are the result of a set of environmental, systemic and genetic causal agents that reveal a multifactorial etiology model, which in anterior teeth produces a serious aesthetic problem, converted into a…
- Conditions
- Children, Adult, Molar Incisor Hypomineralization, Dental Diseases, Opacity
- Trial name
- NCT05597956
- Testing
- white defects, yellow defects, brown defects
- Where
- Spain
- Volunteers
- 110 people
- Sponsor
- University of Valencia
Pain and Anxiety in Children With MIH
Preemptive Analgesia for Pain and Anxiety Control in Children With MIH
This randomized, triple-blinded clinical trial aims to evaluate the effect of preemptive analgesia using ibuprofen on pain perception and anxiety during restorative treatment of first permanent molars in children diagnosed with…
- Trial name
- NCT07374354
- Testing
- ibuprofen 100mg/ml oral suspension syrup
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- October University for Modern Sciences and Arts
Dental Enamel Hypomineralization
Clinical Success of Stainless Steel Crowns Applied Using Different Cements
The main question of the study was to evaluate the one-year clinical success of SSc bonded with two different cement types in MIH teeth with excessive material loss.
- Trial name
- NCT06318520
- Testing
- Use of Calcium silicate based resin cement and resin modified glass ionomer cement
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Afyonkarahisar Health Sciences University
Dental Restoration, Caries
Cold Plasma for Dental Restoration and Caries Prevention
The main objective of this entire research project is to develop a miniature atmospheric cold plasma brush (m-ACPB) for dental clinical applications.
- Trial name
- NCT01529606
- Testing
- Composite restoration and tooth cleaning, Plasma treatment
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Nanova, Inc
Amelogenesis Imperfecta, Dental Age Estimation
Dental Age Estimation by Different Methods in Patients With Amelogenesis Imperfecta
The aim of this study is to investigate whether there is a significant difference in dental age between children with amelogenesis imperfecta (AI) and healthy controls using Cameriere European formula and London Atlas.
- Trial name
- NCT05343247
- Testing
- Cameriere method, London Atlas method
- Where
- Turkey (Türkiye)
- Volunteers
- 416 people
- Sponsor
- Istanbul University