Clinical trials: Disorder of Vein
Idiopathic Intracranial Hypertension
Venous Sinus Stenting With the River Stent in IIH
The objective of the study is to show that stenting the transverse-sigmoid sinus with the River stent is safe and has probable benefit to relieve clinical symptoms in subjects with idiopathic intracranial hypertension (IIH).
- Trial name
- NCT03556085
- Testing
- Venous sinus stenting (Serenity River)
- Where
- 6 sites in United States
- Volunteers
- 39 people
- Sponsor
- Serenity Medical, Inc.
Macular Edema
Study Assessing AR-1105 in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)
This study will evaluate the safety, tolerability and efficacy of AR-1105 (dexamethasone implant) for the treatment of macular edema (ME) due to retinal vein occlusion (RVO).
- Trial name
- NCT03739593
- Testing
- AR-1105-CF1, AR-1105-CF2
- Where
- 11 sites in United States
- Volunteers
- 49 people
- Sponsor
- Aerie Pharmaceuticals
Atrial Fibrillation, Venous Thromboembolism
START-Register: Survey on Anticoagulated Patients Register
This is a phase 4 cohort prospective, open, national, multicentre study that collects data on history of patients treated chronically with anticoagulant drugs, including the novel direct oral anticoagulants (DOACs).
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases or Prosthesis
- Trial name
- NCT02219984
- Testing
- Anticoagulants
- Where
- Italy
- Volunteers
- 15,410 people
- Sponsor
- GUALTIERO PALARETI
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Cervical Cancer
Radiation Therapy With or Without Cisplatin or Fluorouracil in Treating Patients With Cancer of the Cervix
RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00003078
- Testing
- cisplatin, fluorouracil, brachytherapy
- Where
- 66 sites in United States, Canada
- Volunteers
- 870 people
- Sponsor
- Gynecologic Oncology Group
Stroke, Cerebral Palsy
Modulation of Brain Plasticity After Perinatal Stroke
Newborn stroke is the leading cause of a common type of cerebral palsy (CP) that affects thousands of Canadian children and families.
- Trial name
- PLASTIC CHAMPS (NCT01189058)
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), Constraint-induced movement therapy (CIMT)
- Where
- Canada
- Volunteers
- 64 people
- Sponsor
- University of Calgary
Covid19, Corona Virus Infection
Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events
An estimated 22% of the global population is at an increased risk of a severe form of COVID-19, while one in four coronavirus patients admitted to intensive care unit will develop a pulmonary embolism.
- Conditions
- Covid19, Corona Virus Infection, Thrombosis, ARDS
- Trial name
- iGenes-COVID19 (NCT04519398)
- Testing
- Complete thrombophilic profile testing by multiplex PCR
- Where
- Romania
- Volunteers
- 60 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Hepatocellular Carcinoma
A Study of Laparoscopic Middle Hepatic Vein Guidance and Traditional Anatomic Hemihepatectomy
The study, entitled "RCT study of laparoscopic middle hepatic venous guidance versus conventional ananatomical hemihepatectomy", was designed to compare the efficacy of two different ananatomical hemihepatectomy procedures under…
- Trial name
- NCT04422249
- Testing
- laparoscopic middle hepatic vein guidance anatomic hemihepatectomy
- Where
- China
- Volunteers
- 95 people
- Sponsor
- Southwest Hospital, China
Venous Thromboembolism, Deep Venous Thrombosis
A Study Comparing Abelacimab to Apixaban in the Treatment of Cancer-associated VTE
This is a Phase 3,multicenter, randomized, open-label, blinded endpoint evaluation study comparing the effect of abelacimab relative to apixaban on venous thromboembolism (VTE) recurrence and bleeding in patients with cancer…
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolism
- Trial name
- ASTER (NCT05171049)
- Testing
- Abelacimab, Apixaban
- Where
- 209 sites in United States, Australia and 19 more
- Volunteers
- 1,150 people
- Sponsor
- Anthos Therapeutics, Inc.
Chronic Venous Disease
Mobile Phone Thermal Imaging Assessment of Incompetent Perforator Veins
Chronic venous disease is a common disease of the lower limbs. Severe CVD can lead to lower limb swelling, pigmentation, and repeated skin ulceration, which seriously affects patients' quality of life.
- Trial name
- NCT06834555
- Testing
- Mobile phone thermal imaging
- Volunteers
- 100 people
- Sponsor
- Guangdong Second Provincial General Hospital
Atrial Fibrillation, Persistent
The Chinese Registration Study of Driver Ablation of Persistent Atrial Fibrillation.
This is an open label, multi-center, randomized parallel control clinical trial, to demonstrate the role of driver mechanism in maintenance substrate of persistent atrial fibrillation, and evaluate the clinical outcomes of driver…
- Trial name
- NCT04489004
- Testing
- Driver ablation+CPVI, Stepwise ablation
- Where
- China
- Volunteers
- 1,298 people
- Sponsor
- Shanghai Chest Hospital
Achilles Tendon Rupture, Ankle Fractures
Swedish Multicenter Trial of Outpatient Prevention of Leg Clots
Lower limb immobilization is associated with high risk of complications, i.e. venous thromboembolism (VTE) and failed healing. Pharmacoprophylaxis of VTE is in leg-immobilized patients, however, low- or non-effective and…
- Conditions
- Achilles Tendon Rupture, Ankle Fractures, Venous Thromboembolism
- Trial name
- StopLegClots (NCT03259204)
- Testing
- Adjuvant IPC
- Where
- Sweden
- Volunteers
- 1,400 people
- Sponsor
- Karolinska University Hospital
Hepatocellular Carcinoma
The Synergistic Effect of Portal Venous Supply Control and Immunotherapy in Hepatocellular Carcinoma
Hepatocellular carcinoma is one of the most common solid malignant tumors. The prognosis of unresectable hepatocellular carcinoma is very poor.
- Trial name
- NCT05760430
- Testing
- PVE+cTACE+Camrelizumab+Apatinib, cTACE+Atirizumab+Bevacizumab
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Varicose Veins
Ambulatory Surgery of Lower Extremity Varicose Vein
OBJECTIVE: To retrospectively analyze the results of ambulatory treatment on Taiwanese patients with primary varicosities of the lower extremities including the use of endovenous laser, phlebectomy, and sclerotherapy.
- Trial name
- NCT00702897
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Far Eastern Memorial Hospital
Atrial Fibrillation, Arrhythmia
Unipolar Atrial Electrogram Modification Combined to the Contact Force Sensing Technology for Pulmonary Vein Isolation
Prospective observational multicentric study evaluating the efficacy of considering unipolar signal modification during radio frequency catheter ablation of patients with symptomatic paroxysmal atrial fibrillation in France…
- Trial name
- Uniforce (NCT02520960)
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Hôpital Privé Les Franciscaines
Liver Disease
Correlation and Comparison of the HepQuant® Disease Severity Index (DSI) With Hepatic Venous Pressure Gradient (HVPG)
This study plans to learn more about a new test to look at liver function, the HepQuant-Shunt (HQ-Shunt). The HQ-Shunt is being evaluated for safety and effectiveness as an alternative to Hepatic Venous Pressure Gradient testing…
- Trial name
- NCT02523196
- Testing
- HepQuant-SHUNT (Drug and Device) #65,123 (4D-cholate) and IND #65,121 (13C-cholate), Hepatic Venous Pressure Gradient (HVPG)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Colorado, Denver
Venous Thromboembolic Disease
Predictors of Attempted Inferior Vena Cava Filters Retrieval.
The InferiorVena Cava (IVC) with filters has been recommended when there is a contraindication or a failure of anticoagulation. Due to the side effects related to the filters, it is recommended to remove them as soon as possible.
- Trial name
- NCT04846725
- Testing
- Data collection
- Where
- France
- Volunteers
- 356 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Deep Venous Thrombosis, Colonic Cancer
Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer
The chemoprophylaxis of deep vein thrombosis (DVT) with subcutaneous low-molecular-weight heparin (enoxaparin) in the postoperative period of elective surgeries is already well established in the literature and in clinical…
- Trial name
- Ésquilo (NCT05303818)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Hospital do Servidor Publico Estadual
Obstructive Sleep Apnea, Venous Thrombosis
Obstructive Sleep Apnea and Venous Thromboembolism
There is a clear link between obstructive sleep apnea (OSA) and cardiovascular disease. However, there has been no clear link between OSA and venous thromboembolism (VTE). The objective of this study is to evaluate such a link.
- Conditions
- Obstructive Sleep Apnea, Venous Thrombosis, Pulmonary Embolism, Venous Thromboembolism
- Trial name
- OSAVTE (NCT01051297)
- Volunteers
- 85 people
- Sponsor
- University of Missouri-Columbia
ICU Patients Requiring a Central Venous Access
Chlorhexidine vs Povidone Iodine in Alcoholic Solutions for Prevention of Central Venous Catheter Infection
The best antiseptic solution for cateheter care remains unknown.High concentration in aquous solution or low concentration in alcoholic solution of chlorhexidine actbetter than povidone iodine in aquous solutions.
- Trial name
- NCT00259350
- Testing
- Skin disinfection
- Where
- France
- Volunteers
- 520 people
- Sponsor
- Poitiers University Hospital
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