Clinical trials: Disorder of Vein
Deep Vein Thrombosis
Whole-leg Ultrasound in Pregnant Patients
This study seeks to determine the rate of thromboembolic complications (blood clots), including death attributed to thromboembolic disease, when anticoagulation (blood thinner) therapy is withheld from pregnant patients suspected…
- Trial name
- CLOT-3 (NCT01319474)
- Testing
- Whole-leg compression ultrasound
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- Intermountain Health Care, Inc.
Diagnoses Disease
Establish Diagnostic Models Based on Portal Venous Blood for Pancreatic Cancer
Explore new markers based on portal venous blood sampling to establish novel diagnostic models for identification of malignant pancreatic mass.
- Trial name
- NCT04536220
- Testing
- Endoscopic Ultrasound (EUS), Fine Needle Aspiration
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT)
Cancer Venous Thromboembolism (VTE)
The primary objective is to demonstrate the non-inferiority of edoxaban (preceded by a short course of LMWH) compared with dalteparin for the prevention of the combined outcome of recurrent venous thromboembolism (VTE) or major…
- Conditions
- Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Cancer
- Trial name
- NCT02073682
- Testing
- Edoxaban, Dalteparin, Low molecular weight heparin
- Where
- 9 sites in United States, Belgium and 4 more
- Volunteers
- 1,046 people
- Sponsor
- Daiichi Sankyo
Stasis Dermatitis
Study Evaluating Efficacy and Safety of Crisaborole in Adults With Stasis Dermatitis
This is a Phase 2a, randomized, double blind, vehicle controlled, parallel group, proof of concept study that will include participants with stasis dermatitis without active skin ulceration, who will receive crisaborole ointment…
- Trial name
- NCT04091087
- Testing
- crisaborole ointment, vehicle ointment
- Where
- 4 sites in United States
- Volunteers
- 66 people
- Sponsor
- Pfizer
Venous Disease
Efficacy on Pain Following a Procedure for Injecting Sclerotherapeutic Foam Into the Great Saphenous Vein
The trial objectives are to compare efficacy relative to pain, along the route of the vein following echoguided endovenous injection of sclerotherapeutic foam into the Great Saphenous vein, of class III microfibre compression…
- Trial name
- NCT01368159
- Testing
- Compression Stockings
- Volunteers
- 120 people
- Sponsor
- Le Club Mousse
Atrial Fibrillation, Sleep Apnea, Obstructive
Origin of Premature Atrial Beats Induced by Simulated Obstructive Sleep Apnea
There is accumulating evidence for obstructive sleep apnea (OSA) as an independent risk factor for paroxysmal atrial fibrillation and for high recurrence rates of atrial fibrillation after ablation therapy.
- Conditions
- Atrial Fibrillation, Sleep Apnea, Obstructive, Atrial Premature Complexes
- Trial name
- NCT02269774
- Testing
- Standard pulmonary vein isolation
- Where
- Switzerland
- Volunteers
- 2 people
- Sponsor
- University of Zurich
Blood Coagulation Disorders, Venous Thromboembolism
Monitoring Trends in Venous Thromboembolism
To describe time trends in the epidemiology of venous thromboembolism.
- Conditions
- Blood Coagulation Disorders, Venous Thromboembolism, Cardiovascular Diseases
- Trial name
- NCT00063518
- Sponsor
- University of Massachusetts, Worcester
Retinal Vein Occlusion
Minocycline to Treat Central Retinal Vein Occlusion
Background: Central retinal vein occlusion (CRVO) is a blockage of the main vein that carries blood away from the retina in the back of the eye.
- Trial name
- NCT01468844
- Testing
- Minocycline, Bevacizumab
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 6 people
- Sponsor
- National Eye Institute (NEI)
Overweight and Obesity, Emergencies
Nurse-led Placement of Peripheral Venous Catheters in Overweight Patients Using Standard or Dynamic Ultrasound-guided Technique
Overweight and obesity may be associated with difficult intravenous access leading to longer procedure time and more placement attempts of peripheral venous catheters (PVC).
- Trial name
- DUST (NCT04412967)
- Testing
- Dynamic ultrasound-guided short-axis needle tip navigation, Standard technique of placing a PVC
- Where
- Sweden
- Volunteers
- 89 people
- Sponsor
- University Hospital, Linkoeping
Venous Thromboembolism, Arthroplasty, Replacement, Hip
A Study Evaluating Efficacy and Safety of YM150 Compared to Enoxaparin in Subjects Undergoing Hip Replacement Surgery
The purpose of this study is to evaluate the efficacy and safety of various doses of YM150 (the experimental drug) compared to enoxaparin in the prevention of venous thromboembolism in patients that are undergoing elective hip…
- Trial name
- ONYX-3 (NCT00902928)
- Testing
- YM150, enoxaparin
- Where
- 156 sites in United States, Australia and 26 more
- Volunteers
- 1,992 people
- Sponsor
- Astellas Pharma Europe B.V.
Intrauterine Growth Restriction
FETAL PULMONARY VEIN AND UMBILICAL ARTERY PULSATILITY INDICES AS PREDICTORS OF FETAL GROWTH RESTRICTION IN DIABETIC AND HYPERTENSIVE PREGNANT WOMEN
Diabetic and hypertensive pregnant women attending at Kasr Alani for antenatal care were subjected to Complete History taking. All the participants were scanned using B mode sonography to determine the fetal biometric parameters…
- Trial name
- NCT06988436
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 82 people
- Sponsor
- Cairo University
Heart Failure, Respiratory Insufficiency
A Study of Rivaroxaban (JNJ-39039039) on the Venous Thromboembolic Risk in Post-Hospital Discharge Patients
The purpose of this study is to evaluate the efficacy and safety of rivaroxaban compared with placebo in the prevention of symptomatic venous thromboembolism (VTE) events and VTE-related death post-hospital discharge in…
- Conditions
- Heart Failure, Respiratory Insufficiency, Stroke Acute, Infectious Diseases
- Trial name
- MARINER (NCT02111564)
- Testing
- Rivaroxaban, 10 mg, Rivaroxaban, 7.5 mg
- Where
- 593 sites in United States, Argentina and 35 more
- Volunteers
- 12,024 people
- Sponsor
- Janssen Research & Development, LLC
Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers
Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds
Use of a motorized waterjet to debride wounds to improve healing outcomes.
- Conditions
- Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries
- Trial name
- NCT07653165
- Testing
- Motion NPWT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Boca Center for Wound Healing
Atrial Fibrillation
Release of Acetylcholine From the Ganglionated Plexus During the Thaw Phase of Cryoballon Pulmonary Vein Ablation (GP RESPONSE Study)
Determine whether the presence of acetylcholine in the systemic circulation, correlates with the hypotensive response observed during the thaw phase of cryoballoon ablation.
- Trial name
- NCT03636100
- Testing
- Cryoballoon ablation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Saint Luke's Health System
Macular Edema, Retinal Vein Occlusion
Safety and Effectiveness of Bevacizumab Intravitreal Injections in the Treatment of Macular Edema Secondary to Retinal Vein Occlusion
Lack of an effective treatment for macular edema secondary to central retinal vein occlusion and the bad response to grid laser treatment in patients with macular edema secondary to branch retinal vein occlusion, together with…
- Trial name
- EBOVER (NCT00970957)
- Testing
- Avastin Intravitreal Injection
- Where
- 13 sites in Spain
- Volunteers
- 107 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Gynecologic Neoplasms, Venous Thromboembolism
Thromboprophylaxis After Surgery for Gynecologic Malignancy in China
Venous thromboembolism (VTE) is an important cause of post-operative morbidity and mortality in women undergoing surgery for gynecologic malignancies.
- Conditions
- Gynecologic Neoplasms, Venous Thromboembolism, Low Molecular Weight Heparin, Argatroban
- Trial name
- NCT02935530
- Testing
- s-LMWH, LMWH, Argatroban
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Huazhong University of Science and Technology
Colorectal Surgery, VTE (Venous Thromboembolism)
A Multicenter, Open-Label, Non-Inferiority Randomized Controlled Trial of Postoperative VTE Prevention in Chinese Patients After Colorectal Cancer Surgery
research objective 1. Optimize VTE prevention management after CRC surgery. 2. Improve the prevention and treatment level of VTE in current perioperative patients. 3. Reduce the social burden of VTE related diseases.
- Trial name
- NCT06583330
- Testing
- Low Molecular Weight Heparin (dalteparin)
- Volunteers
- 1,448 people
- Sponsor
- Beijing Friendship Hospital
Venous Insufficiency (Chronic)(Peripheral), Venous Reflux
Adrenaline Reduces Ecchymoses and Hematomas and Improves Quality of Life After Classic Saphenous Vein Stripping
Aim of the present study is to investigate the efficiency of adrenaline (epinephrine) used locally in reducing and avoiding post-operative formation of subcutaneous ecchymoses and hematomas, in comparison with traditional…
- Conditions
- Venous Insufficiency (Chronic)(Peripheral), Venous Reflux, Venous Insufficiency of Leg, Venous Stasis
- Trial name
- ARESQOLSAVES (NCT04758728)
- Testing
- Great saphenous vein stripping and varicectomies, Epinephrine Topical, normal saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Junior Doctors Network-Hellas
Hepatocellular Carcinoma
Comparing the Prognosis of Patients With HCC and PVTT Treated With Surgery Versus Locoregional Therapy.
Hepatocellular carcinoma is prone to invade the portal vein and form portal vein thrombosis, and patients in this period are directly included in the advanced stages, i.e. Barcelona clinical liver cancer stage C.
- Trial name
- NCT06248528
- Testing
- Liver resection, Locoregional therapy
- Where
- China
- Volunteers
- 1,076 people
- Sponsor
- Chen Xiaoping
Paroxysmal Atrial Fibrillation
Influence of an Innovative Telemetric Smartphone Application on Re-hospitalization
A randomized, open, mono-centric pilot study to investigate the influence of an innovative telemetric smartphone application on re-hospitalization and quality of life after cryoballoon pulmonary vein isolation in patients with…
- Trial name
- TRACE-AF (NCT03268707)
- Testing
- Telemetric smartphone application, Conventional follow up
- Where
- 2 sites in Germany
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
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