Clinical trials: Dissociative Disorder
Laryngopharyngeal Reflux
Predictive Value of Subjective and Objective Measurement Tools for Extraesophageal Reflux
Acid reflux can cause many symptoms in the throat, including discomfort or pain, and difficulty with breathing and voice problems.
- Trial name
- NCT01829074
- Volunteers
- 150 people
- Sponsor
- Respiratory Technology Corporation
Functional Neurological Disorder, Convulsion, Non-Epileptic
Establishment of an Interdisciplinary Functional Neurological Disorder (FND) Treatment Program and Development of a Clinical Care Pathway for FND
The purpose of this study is to help providers develop an interdisciplinary treatment pathway for functional neurological disorder (FND) at University of Alabama at Birmingham (UAB), and will involve psychiatry, speech therapy…
- Conditions
- Functional Neurological Disorder, Convulsion, Non-Epileptic, Functional Seizure
- Trial name
- NCT06362161
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- University of Alabama at Birmingham
Functional Neurological Symptom Disorder
Trial Of Neurostimulation Treatment and Investigation for Causes of Functional Motor Symptoms: a Pilot Study
A pilot randomised controlled trial (RCT) of single-pulse transcranial magnetic stimulation (TMS) over the motor cortex to investigate efficacy in improving motor FND symptoms and to make a preliminary investigation of predictors…
- Trial name
- TONICS (NCT05829005)
- Testing
- Transcranial magnetic stimulation (TMS)
- Where
- United Kingdom
- Volunteers
- 51 people
- Sponsor
- King's College London
Functional Neurological Disorder, Motor FND
Impact of Theta Burst Repetitive Transcranial Magnetic Stimulation on the Patient's Self-reported Improvement in Their Motor Functional Neurological Disorder
Functional neurological disorder (FND) is a condition that causes significant suffering and disability. It is defined by the presence of neurological symptoms that interfere with an individual's functioning and are not consistent…
- Trial name
- Thêta-mTNF (NCT07527403)
- Testing
- theta-burst rTMS (repetitive transcranial magnetic stimulation)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Hospital Center Guillaume Régnier
Dissociative Disorders
Psychopathology of Dissociative Disorders
The goal of the project is to investigate the prevalence of dissociative disorders in psychiatric inpatients in Taiwan. Relevant clinical issues, including common psychiatric comorbidity (e.g., positive psychotic symptoms)…
- Trial name
- NCT01388140
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Convulsion, Nonepileptic, Conversion Disorder
Comparing Different Treatments in Reducing Dissociative Seizure Occurrence
The study will test the hypothesis that Cognitive Behavioural Therapy plus Standardised Medical Care (SMC) will have greater clinical and cost effectiveness than SMC alone in treating adult patients with dissociative seizures…
- Conditions
- Convulsion, Nonepileptic, Conversion Disorder, Dissociative Disorder
- Trial name
- CODES (NCT02325544)
- Testing
- Cognitive Behavioral Therapy, Standardized Medical Care
- Where
- 40 sites in United Kingdom
- Volunteers
- 368 people
- Sponsor
- King's College London
Schizophrenia, Autistic Disorder
Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum
The schizophrenic disorders and pervasive developmental disorders are neurodevelopmental disorders distinct origin who share common challenges to engage and maintain social relationships and mutual disturbances of affective…
- Trial name
- NCT01805128
- Testing
- Facial recognition of emotions, understanding metaphors, Attribution of intentionality to others in social situations depending on the type of situation
- Where
- 3 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Psychogenic Nonepileptic Seizures (PNESs), Post Traumatic Stress Disorder PTSD
Treatment for Psychogenic Nonepileptic Seizures and Post-traumatic Stress Disorder Using Prolonged Exposure Therapy (PE) or Psychoeducation for PNES
An outpatient randomized controlled clinical trial conducted at the Northeast Regional Epilepsy Group's PNES Program, involving mental health clinicians certified in PE and trained in administering PsychoEd.
- Trial name
- PNES (NCT07344766)
- Testing
- imaginal and in vivo exposure, psychoeducation for psychogenic nonepileptic seizures
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Northeast Regional Epilepsy Group
Headache
Ketamine for Acute Migraine in the Emergency Department
This research study will be a prospective, randomized, double-blind, placebo-controlled trial. Because ketamine has yet to be directly studied as treatment for acute migraine headache in the emergency department, the research…
- Trial name
- NCT02697071
- Testing
- Ketamine, Normal Saline
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Globus
The Effect of Laryngeal Manual Therapy as a Management of Globus
The purpose of this study is to assess the effect of laryngeal manual therapies in the treatment of globus (sensation of a lump in the throat).
- Trial name
- NCT04436146
- Testing
- laryngeal manual therapies
- Where
- Israel
- Volunteers
- 70 people
- Sponsor
- HaEmek Medical Center, Israel
Cerebral Palsy, Gait, Spastic
The Influence of Applying Additional Weight on Crouch Gait in Children With Spastic Cerebral Palsy
The purpose of this study was to investigate the effectiveness of applying additional weight in the improvement of the crouch gait pattern in children with spastic cerebral palsy.
- Conditions
- Cerebral Palsy, Gait, Spastic, Motor Disorders, Functional Neurological Disorder
- Trial name
- NCT06493344
- Testing
- Applying additional weight
- Where
- Greece
- Volunteers
- 2 people
- Sponsor
- University of Thessaly
Mild Traumatic Brain Injury, Functional Neurological Disorder
Rehabilitation for Functional Memory Symptoms After Concussion
This study aims to evaluate the feasibility of novel cognitive behavioural therapy (CBT)-based intervention designed to improve functional memory symptoms after concussion.
- Trial name
- NCT05581810
- Testing
- Cognitive Behavioural Therapy (CBT), Cognitive Rehabilitation
- Where
- 10 sites in Canada
- Volunteers
- 30 people
- Sponsor
- University of British Columbia
Functional Movement Disorder
Action Outcome Latencies as a Measure of Sense of Agency in Functional Movement Disorders.
Functional movement disorders (FMD) are among the most common neurological conditions seen in clinical practice, yet they are poorly understood and often misdiagnosed.
- Trial name
- NCT07302308
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Functional Neurological Disorder
Psilocybin in Functional Neurological Disorder
The goal of this study is to learn about the brain network response in people who have functional neurological disorder who are administered with a single dose of the psychedelic psilocybin with therapeutic support.
- Trial name
- PsiFUND (NCT05723276)
- Testing
- Psilocybin
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- King's College London
Functional Neurological Disorder, Conversion Disorder
Brain-computer Interface Rehabilitation And Virtual Environments in Functional Neurological Disorder (BRAVE-FND)
The purpose of this study is to determine whether a course of rehabilitation using a device called a brain-computer interface can change the level of control people feel over bodily movements, in functional neurological disorder.
- Conditions
- Functional Neurological Disorder, Conversion Disorder, Functional Neurological Disorders, Conversion Disorder With Weakness/Paralysis
- Trial name
- BRAVE-FND (NCT07006415)
- Testing
- Brain-computer interface rehabilitation
- Volunteers
- 24 people
- Sponsor
- King's College London
Functional Neurological Disorder, Conversion Disorder
Restoring Independence With Stimulation-Enhanced Treatment for People With Functional Neurological Disorder
The goal of this clinical trial is to test a new treatment for adults with walking problems due to Functional Neurological Disorder (FND).
- Trial name
- RISE-FND (NCT07769970)
- Testing
- Stimulation-Enhanced Physical Therapy, Active Comparator
- Where
- New Zealand
- Volunteers
- 60 people
- Sponsor
- University of Auckland, New Zealand
Compare the Response Rate of Atypical GERD After PPI Therapy
Comparison of the Efficiency of Two Different PPI Formula in Atypical GERD
Patients with atypical gastro-esophageal reflux disease (GERD), include cough, globus, and non-cardiac chest pain (NCCP) usually require more aggressive or double dose proton pump inhibitor (PPI) therapy than patients with typical…
- Trial name
- NCT03418337
- Testing
- dexilansoprazole (Dexilant 60 mg), lansoprazole (Takepron OD 30 mg)
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Functional Neurological Symptom Disorder
Eye MOvement DesensItisation and Reprocessing Therapy (EMDR) for FunctIonal Neurological Disorder (FND)
Functional Neurological Disorder (FND) is a problem with the functioning of the nervous system and how the brain and body send and receive signals, rather than due to neurological disease or injury.
- Trial name
- MODIFI (NCT05455450)
- Testing
- Eye movement desensitisation and reprocessing therapy, Neuropsychiatric care
- Where
- 2 sites in United Kingdom
- Volunteers
- 50 people
- Sponsor
- South West London and St George's Mental Health NHS Trust
Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease
Sub-dissociative Dose Ketamine in Treatment of Vaso-occlusive Pain Event in Children and Young Adults
The purpose of this research is to see if ketamine is effective and safe in treating children and young adults with sickle cell disease experiencing sickle cell related pain.
- Conditions
- Sickle Cell Disease, Vaso-Occlusive Pain Episode in Sickle Cell Disease, Ketamine Infusion, Pain Management
- Trial name
- NCT07369024
- Testing
- Sub-dissociative Ketamine Infusion
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Mohsen Saidinejad
Major Depressive Disorder, Post Traumatic Stress Disorder
Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)
This observational registry aims to collect real-world data on ketamine use in psychiatric inpatients within a regional tertiary-reference center.
- Conditions
- Major Depressive Disorder, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder, Somatoform Disorders
- Trial name
- KetGD (NCT05565352)
- Testing
- Ketamine Hydrochloride
- Where
- Poland
- Volunteers
- 140 people
- Sponsor
- Medical University of Gdansk