Clinical trials: Distal Femur Fracture
Femoral Fractures
A Multicenter Randomized Trial Comparing IM Nails and Plate Fixation in Distal Femur Fractures
This study looks at two (2) types of surgical treatments and hopes to answer the question, "which is the best way to surgically treat a distal femur fracture?" Both procedures being studied are standard of care (used routinely)…
- Trial name
- NCT00429663
- Testing
- reamed, interlocking intramedullary nail, locking periarticular plate
- Where
- 22 sites in United States
- Volunteers
- 160 people
- Sponsor
- Boston Medical Center
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Humerus Fracture, Femur Fracture
Evaluation of Handling and Possible Complications Related to the Newly Developed Angular Stable Locking System (ASLS)
In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. Due to the play between screw and nail, the reduction can be lost and the instability can result in malunions…
- Conditions
- Humerus Fracture, Femur Fracture, Tibia Fracture
- Trial name
- ASLS-Pre (NCT00793637)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 30 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Distal Femoral Fractures, Extra-articular Distal Radius Malunions
Retrograde Nail vs Double Plating for Distal Femoral Extra and Simple Articular Fractures With Metaphyseal Comminution
The objective of this study is to compare the short term functional clinical and radiological outcomes of retrograde nail versus double plating for distal femoral extra-articular and simple articular fractures with metaphyseal…
- Conditions
- Distal Femoral Fractures, Extra-articular Distal Radius Malunions, Intramedullary
- Trial name
- NCT07542249
- Testing
- Retrograde nail, Double plating
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Benha University
Distal Femur Fracture, Geriatrics
DP Vs DFR for Management of Geriatric Distal Femur Fractures.
The aim of this study was to compare the functional and radiological outcomes of fixation by using double plating technique versus replacement using distal femur tumor prothesis as a primary management for the distal femoral…
- Trial name
- NCT05363943
- Testing
- double plating, Distal femoral replacement
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Amr Gamaleldin Mahmoud Khalil Gendya
Femoral Fractures
Evaluation of the Effects of Less Invasive Stabilization System (LISS) Plating Techniques in Distal Femoral Fractures
The purpose of this study is to determine whether the rate of fracture healing and fracture union, repaired with the LISS device, will be as good as or better than the usual fracture fixation systems.
- Trial name
- NCT00552331
- Testing
- Plates to treat fractures of the distal femur, LISS
- Where
- Canada
- Volunteers
- 150 people
- Sponsor
- Nova Scotia Health Authority
Proximal (Subtrochanteric)Femoral Fractures, Distal Femoral Fractures
Evaluation of the Safety and Efficacy of a Guided Bone Regeneration Membrane for the Treatment of Femoral Fractures
Certain types of fractures require surgical intervention that may involve the use of bone grafts or bone graft substitutes. Many of the materials used as bone graft substitutes suffer from disadvantages such as soft tissue…
- Trial name
- NCT01687530
- Testing
- AMCA Bone Membrane.
- Where
- 2 sites in Israel
- Volunteers
- 48 people
- Sponsor
- RegeneCure, Ltd.
Humeral Neck Fracture, Vertebral Fracture
Integrated Rehabilitation Program for Fractures
The recovery of range of motion and muscle power after surgical intervention of the fracture will mostly affect patient's daily activities. So postoperative rehabilitation program will play the important role.
- Conditions
- Humeral Neck Fracture, Vertebral Fracture, Distal Radial Fracture, Hip Fractures
- Trial name
- NCT01817933
- Testing
- physical therapy
- Sponsor
- Changhua Christian Hospital
Distal Femur Fracture, Periprosthetic Fractures
Safety and Performance of the Biphasic Plate Distal Femur: A Multicenter Case Series
The goal of this observational multicenter case series is to assess the safety and performance of the CE-marked "Biphasic Plate Distal Femur" during standard of care.
- Conditions
- Distal Femur Fracture, Periprosthetic Fractures, Intra-Articular Fractures, Supracondylar Fracture
- Trial name
- NCT06028971
- Where
- 5 sites in Germany, Switzerland
- Volunteers
- 60 people
- Sponsor
- 41medical AG
Periprosthetic Fractures, Distal Femur Fractures
Periprosthetic Distal Femur Fracture
A periprosthetic distal femur fracture is a fracture close to a knee implant. This type of fracture is often difficult to fix because of the close proximity of the two surgical implants which can sometimes interfere with proper…
- Trial name
- NCT01973712
- Testing
- Locked Compression Plating, Retrograde Intramedullary Nailing (RIMN)
- Where
- Canada
- Volunteers
- 94 people
- Sponsor
- Unity Health Toronto
Supracondylar Femoral Fractures, Femoral Fractures
Robot-Assisted Closed Reduction and Internal Fixation for Distal Femoral Fractures
This study aims to evaluate the clinical efficacy and safety of an intelligent robotic system for the closed reduction of extra-articular supracondylar femoral fractures (Arbeitsgemeinschaft für Osteosynthesefragen/Orthopaedic…
- Trial name
- NCT07738406
- Testing
- Robot-assisted closed reduction, Conventional fracture reduction and internal fixation
- Where
- 2 sites in China
- Volunteers
- 80 people
- Sponsor
- Beijing Jishuitan Hospital
Distal Femur Fracture
Distal Femur Fx: ORIF(Open Reduction and Internal Fixation) vs DFR (Distal Femur Replacement Total Knee Arthroplasty)
Supracondylar femur periprosthetic fractures about a total knee arthroplasty (TKA) are a catastrophic and challenging complication of TKA and unfortunately are increasing in incidence.
- Trial name
- NCT05792189
- Testing
- Timed Up and Go Test on subjects with ORIF of distal femur fractures, Koos Jr assesment on subjects with ORIF of distal femur fractures, Timed Up and Go Test on subjects with DFR of distal femur fracture
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Florida
Osteoarthritis, Knee, Rheumatoid Arthritis
A Comparison of Two Surgical Techniques Using the Unity Knee™ Total Knee System
A comparison of two Unity Knee™ tissue-balancing techniques by analysing the results from X-rays and patient questionnaires.
- Conditions
- Osteoarthritis, Knee, Rheumatoid Arthritis, Post-Traumatic Osteoarthritis of Knee, Varus Deformity, Not Elsewhere Classified, Knee
- Trial name
- NCT03511144
- Testing
- Unity Knee™ TKR using measured resection, Unity Knee™ TKR using ligament balancing
- Sponsor
- Corin
Hip Fracture
Influence of Static Distal Locking of a Short Proximal Femoral Nail
Prospective, comparative, randomized, double-blind study to evaluate the outcomes of trochanteric nailing in unstable hip fractures with and without a distal interlocking screw.
- Trial name
- NCT06357312
- Testing
- hip trochanteric nail
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Elda University Hospital
Femoral Fractures, Tibial Fractures
Reamed Locked Plating - Metaphyseal Fractures of the Distal Femur and Tibia
Comminuted metaphyseal fractures (OTA classification A2/3 and C2/3) of the distal femur and distal tibia are difficult to treat and typically have more complications than other metaphyseal fractures.
- Trial name
- NCT01553630
- Testing
- RIA bone graft, Surgery without bone graft
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Florida Orthopaedic Institute
Infected Distal Femoral Fractures, Knee Stiffness
Preventing Knee Stiffness in Infected Distal Femoral Fractures in Children
The goal of this observational study is to prevent keen stiffness health in in Infected Distal Femoral Fractures in Children. This prospective study aimed to compare the effects of early patellar traction versus no patellar…
- Trial name
- ABCCI (NCT07864441)
- Testing
- Patellar Traction
- Volunteers
- 101 people
- Sponsor
- The Second Hospital of Qinhuangdao
Distal Femur Fracture, Tibial Plateau Fracture
Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries
The overall objective of this study is to compare outcomes following early advanced weight bearing (EAWB) using the AlterG antigravity treadmill versus standard of care physical therapy for adult patients with lower extremity…
- Conditions
- Distal Femur Fracture, Tibial Plateau Fracture, Distal Tibia Fracture, Pilon Fracture
- Trial name
- AlterG (NCT03562364)
- Testing
- AlterG anti-gravity treadmill
- Where
- 10 sites in United States
- Volunteers
- 81 people
- Sponsor
- Major Extremity Trauma Research Consortium
Distal Radius Fracture, Osteoporosis
Utility of Cortical Bone Tissue Properties in the Assessment of Fracture Risk
The objective of this study is to determine whether a new minimally invasive method for in vivo measurement of cortical bone tissue properties can identify those who are at risk for fragility fractures of the hip and radius.
- Conditions
- Distal Radius Fracture, Osteoporosis, Hip Fractures
- Trial name
- NCT03076034
- Testing
- Reference Point Indentation
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Distal Femur Fracture
DIFFIR - Geriatric Distal Femur Fixation Versus Replacement
The current standard of care for most intra-articular distal femur fractures (above the knee joint) in geriatric patients is a surgical fixation using plates and screws to hold the fracture pieces in the correct position, until…
- Trial name
- DIFFIR (NCT04076735)
- Testing
- Distal femoral replacement, Surgical Fixation (ORIF)
- Where
- Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
Traumatic; Lesion, Degenerative Lesion of Articular Cartilage of Knee
Randomized Evaluation of BST-CarGel Versus Microfracture Alone On Recovery From Distal Femoral Cartilage Lesions
This multi-centre randomized, controlled trial will assess the impact of BST-CarGel scaffold with microfracture versus microfracture alone on short and long term clinical benefit in patients with cartilage lesions of the femoral…
- Trial name
- RECORD (NCT02981355)
- Testing
- Microfracture treatment, BST-CarGel
- Where
- 15 sites in Australia, Canada and 5 more
- Volunteers
- 5 people
- Sponsor
- Piramal Healthcare Canada Ltd