Clinical trials: Distal Subungual Onychomycosis
Distal and Lateral Subungual Onychomycosis
Safety and Efficacy of Luliconazole Solution, 10% in Subjects With Mild to Moderate Onychomycosis
The purpose of this study is to determine the safety and efficacy of a topical antifungal formulation, Luliconazole Solution, 10%, in the treatment of adults with onychomycosis of the toenails.
- Trial name
- SOLUTION (NCT01431820)
- Testing
- Luliconazole Solution, 10%, Vehicle Solution
- Where
- 28 sites in United States
- Volunteers
- 334 people
- Sponsor
- Topica Pharmaceuticals
Onychomycosis
A Vehicle-controlled Study of Topical MOB015B in the Treatment of Distal Subungual Onychomycosis (DSO)
This is a Phase 3 multicenter, double-blind study to evaluate the safety and efficacy of vehicle-controlled topical MOB015B in the treatment of Distal Subungual Onychomycosis (DSO)
- Trial name
- NCT05279846
- Testing
- MOB015B
- Where
- 35 sites in United States, Canada
- Volunteers
- 350 people
- Sponsor
- Moberg Pharma AB
Onychomycosis
Treatment of Mild to Moderate Distal Subungual Onychomycosis of the Toenail
The purpose of the study is to determine whether NB002, 0.25%, and 0.5% are safe and effective in the treatment of distal subungual onychomycosis of the toenail.
- Trial name
- NCT00453271
- Testing
- NB-002, Vehicle control
- Where
- 24 sites in United States, Canada
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- NanoBio Corporation
Onychomycosis
Efficacy, Safety, and Tolerability of HTS-519 Insert in Patients With Toenail Fungus of the Big Toenail
The purpose of this study is to assess the efficacy, safety and tolerability of HTS-519 Inserts in the treatment of mild to moderate toenail fungus disease of the big toenail.
- Trial name
- NCT02798380
- Testing
- HTS-519 Insert
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hallux, Inc.
Onychomycosis of Toenail
Safety and Efficacy of Next Science Gel on Toenail Fungus
This is a 52 week, 20-patient open-label pilot study on the safety and efficacy of Next Science Wound gel in the treatment of mild to moderate Distal Subungual Onychomycosis.
- Trial name
- NCT04042857
- Testing
- Next Science Treatment Gel
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Next Science TM
Distal, Subungual Onychomycosis
Study of Different Doses of a Novel Treatment for Onychomycosis
The purpose of the study is to determine the safety and efficacy of 2.5%, 5.0%, and 7.5% AN2690 Solutions compared to the vehicle alone in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT00679770
- Testing
- AN2690, 2.5%, AN2690, 5%, AN2690, 7.5%
- Where
- 4 sites in United States
- Volunteers
- 28 people
- Sponsor
- Pfizer
Onychomycosis
TDT 067 Open Label Multi-Dose Onychomycosis Study
The aim of this study is to establish a clinical bridge to Lamisil® tablets by conducting a clinical pharmacokinetic (PK) study comparing the systemic exposure of a Lamisil® tablet with that of with TDT 067 under maximal use…
- Trial name
- NCT01790165
- Testing
- TDT067 and Lamisil
- Volunteers
- 27 people
- Sponsor
- Celtic Pharma Development Services
Distal, Subungual Onychomycosis
Study of Different Doses of a Novel Treatment for Onychomycosis
The purpose of the study is to determine the safety and efficacy of 2.5%, 5.0%, and 7.5% AN2690 Solutions compared to the vehicle alone in the treatment of distal, subungual onychomycosis of the great target toenail.
- Trial name
- NCT00679965
- Testing
- AN2690, 2.5%, AN2690, 5%, AN2690, 7.5%
- Where
- 9 sites in Mexico
- Volunteers
- 159 people
- Sponsor
- Pfizer
Distal Subungual Onychomycosis
A Study to Evaluate TMI-358 in the Treatment of Distal Subungual Onychomycosis
The purpose of this study is to determine if a local treatment is effective for the treatment of toenail fungus (distal subungual onychomycosis).
- Trial name
- NCT01093118
- Testing
- TMI-358, MMI-467
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Talima Therapeutics, Inc.
Distal Subungual Onychomycosis
A Multi-centre, Double-blind, Randomized, Vehicle-controlled Study of Efficacy and Safety of Topical MOB015B in the Treatment of Mild to Moderate Distal Subungual Onychomycosis (DSO)
The primary objective of this study is to evaluate the efficacy of topical MOB015B in patients with mild to moderate distal subungual onychomycosis (DSO).
- Trial name
- NCT02859519
- Testing
- MOB015B, MOB015B Vehicle
- Where
- 10 sites in United States, Canada
- Volunteers
- 365 people
- Sponsor
- Moberg Pharma AB
Onychomycosis
Erbium-doped Yttrium Aluminium Garnet Laser(Er:Yag)Associated With Amorolfine Lacquer in the Treatment of Onychomycosis
The study aims to investigate the effectiveness of a single application of Er:YAG laser to the nail plate in increasing the efficacy of the amorolfine lacquer used in the treatment of onychomycosis (fungal infection of nails)…
- Trial name
- NCT01528813
- Testing
- Er:YAG laser + amorolfine lacquer, Amorolfine lacquer
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Brasilia University Hospital
Foot Dermatoses
Antifungal Activity of Loceryl Nail Lacquer in Combination With a Cosmetic Varnish
The main objective is to compare efficacy, in terms of antifungal activity of Loceryl Nail Lacquer associated with a Cosmetic Varnish and Loceryl Nail Lacquer alone, in the treatment of mild to moderate toenail Distal Subungual…
- Trial name
- COOL (NCT02321098)
- Testing
- Loceryl NL + Cosmetic varnish, Loceryl NL 12 weeks, Loceryl NL 15 months
- Where
- Iceland
- Volunteers
- 50 people
- Sponsor
- Galderma R&D
Onychomycosis
A Study to Evaluate the Efficacy and Safety of Oral VT-1161 in Patients With Onychomycosis of the Toenail
Several properties of VT-1161 suggest that it might be a safer and more effective treatment for onychomycosis of the toenail (also known as toenail fungus) than other oral antifungal medicines.
- Trial name
- NCT02267356
- Testing
- VT-1161
- Where
- 33 sites in United States
- Volunteers
- 259 people
- Sponsor
- Viamet