Clinical trials: Distension
Hypertension
Bioimpedance and Arterial Distension
The overall objectives were to investigate if characteristic dimensions for tissue and vessels determined from measured bioimpedance spectra would provide the same values as dimensions determined from MR images of the upper arm…
- Trial name
- SenseC1 (NCT01622842)
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Sense A/S
Crohn Disease
Comparing Endoscopic Strictureplasty vs. Balloon Dilation in Crohn's Disease Strictures
Crohn's disease (CD) is an inflammatory bowel disease characterized by chronic ulcers, strictures, and penetrating lesions in the intestinal tract.
- Trial name
- ES vs BD in CD (NCT06203782)
- Testing
- endoscopic stricturoplasty, endoscopic balloon dilation
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cardiovascular Physiology
Effects of Tart Cherry and Aronia Extract Supplementation on Selected Physiological Parameters in Endurance-Trained Men
This study will evaluate the effects of four weeks of oral supplementation with a double-standardized tart cherry (Prunus cerasus) and aronia (Aronia melanocarpa) extract on cardiovascular regulation and exercise performance in…
- Trial name
- NCT07885098
- Testing
- Standardized Tart Cherry and Aronia Extract
- Where
- Poland
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Coronary Artery Ectasia
Arrhythmogenic Risk Assessment in Coronary Artery Ectasia Patients
The investigators thought to explore arrhythmias outcome - hidden arrhythmias, ECG features: Tp-Te interval and Tp-Te/QTc ratio, fQRS among patients with coronary artery ectasia as compared to normal coronary artery patients.
- Trial name
- NCT05106530
- Testing
- Holter, ECG
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Renal Stone
Percutaneous Nephrolithotomy for Treatment of Kidney Stones Greater Than 2 cm
Percutaneous nephrolithotomy (PCNL) is a minimally invasive procedure considered as the treatment of choice for the management of large-scale and fully-formed kidney stones.This procedure has a 5% risk of complications including…
- Trial name
- NCT03189264
- Testing
- percutaneous nephrolithotomy for kidney stones
- Where
- Colombia
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dr Carlos Hernández
Endometrial Biopsy
Oral Misoprostol Before Endometrial Biopsy
An endometrial biopsy involves a thin tube being passed through the cervix (opening of the uterus) to obtain a sample of the lining of the uterus.
- Trial name
- NCT00200226
- Testing
- misoprostol, vitamin B6
- Where
- 2 sites in Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Multiple Sclerosis
Efficacy Study of "Imaginative Distention", a Self Managed Tool to Cope With Fatigue,Insomnia and Stress in pw Insomnia and pw MS
Imaginative Distention (ID) is proposed as supportive and integrative intervention to cope with fatigue, (principal end point), to cope with insomnia, stress perception and to improve QoL of pw MS, insomnia pw and health care…
- Trial name
- DIMMISI (NCT02290990)
- Testing
- "Imaginative Distention" technique
- Where
- Italy
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Niguarda Hospital
Diabetic Nephropathy, Endothelial Dysfunction
Flavonoids in the Treatment of Endothelial Dysfunction in Children With Diabetes
Diabetes is the most common metabolic disease of childhood. Vascular disease is a leading complication of diabetes, and attempts to maintain close glycemic control do not prevent the sequelae that claim the lives and quality of…
- Trial name
- flavonoid (NCT01307917)
- Testing
- flavonoids
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Adhesive Capsulitis
AI-Assisted Ultrasound Therapy for Adhesive Capsulitis
This study aims to integrate artificial intelligence with ultrasound imaging to investigate the dynamic biomechanical characteristics of adhesive capsulitis and to compare the therapeutic effectiveness of three ultrasound-guided…
- Trial name
- NCT07599059
- Testing
- Dual-Target Injection, Rotator Interval Injection, Posterior Recess Injection
- Where
- Taiwan
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Cervical Dilation Prior to Dilation and Evacuation
Same-day Cervical Preparation Before Dilation and Evacuation
The purpose of this randomized trial is to compare same-day cervical preparation using Dilapan-S™ plus buccal misoprostol to overnight cervical preparation using Dilapan-S™ before D\&E at 16.0 to 20.0 weeks.
- Trial name
- NCT03002441
- Testing
- Same-Day Dilapan-S, Overnight Dilapan-S
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Planned Parenthood of Greater New York
Keratoconus, Ectasia
Progressive Keratoconus or Ectasia Treatment Plan
Keratoconus and pellucid marginal degenerations are genetically based ocular conditions and post surgical ectasia is an iatrogenic condition.
- Trial name
- NCT01384773
- Testing
- Riboflavin Solution, UV-X Illumination System
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Stephen Trokel
Dysmenorrhea Primary
The Effect of Cervical Dilatation on Primary Dysmenorrhea
Primary dysmenorrhea (PD) is defined as recurrent, crampy pain occurring with menses in the absence of identifiable pelvic pathology.
- Trial name
- NCT04682262
- Testing
- Cervical dilatation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Healthy Subjects
The Effect of Inhibitory Control Processes Induced by Rectal Distension on Impulse Control Measured by Stroop Task Performance and Intertemporal Discounting.
The aim of this study will be to investigate the effect of rectal distension, controlled by electronic barostat, on cognitive control ability in healthy subjects.
- Trial name
- NCT02043561
- Testing
- induction of urge by rectal distension
- Where
- Belgium
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cardiovascular Disease
Nitric Oxide Bioavailability and Early Life Stress (NO-Stress)
Cardiovascular disease is the leading cause of death in the United States. Other studies have shown that stress, early in life, could be a risk factor for cardiovascular disease, later in life.
- Trial name
- NO-Stress (NCT02115724)
- Testing
- Antioxidant cocktail, Biopsy, NMD; 0.4mg sub-lingual nitroglycerin spray
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Augusta University
Borderline High LDL-cholesterol
Effects of Ubiquinol and Ubiquinone on Vascular Function in Healthy Adults With Borderline High LDL-Cholesterol
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of Ubiquinol and Ubiquinone on vascular endothelial function in generally healthy adults with borderline high LDL-cholesterol.
- Trial name
- NCT07881601
- Testing
- Ubiquinol, Ubiquinone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Dilatation of Cranial Arteries; MMA, STA and MCA, Headache
The Effect of Levcromakalim Infusion on the Cranial Arteries Over Several Hours Using a High Resolution MRA Technique in a Randomized, Double-blind Placebo-controlled Design in Healthy Volunteers.
Healthy participants vill randomly be allocated in a 2:1 order to receive 1 mg levcromakalim or placebo (isotonic saline) for 20 min.
- Trial name
- NCT03609008
- Testing
- Levcromakalim, Saline
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Preterm Birth, Preterm Premature Rupture of Membrane
Cerclage After Full Dilatation Caesarean Section
CRAFT-OBS: Observational Study; To evaluate subsequent pregnancy risk of preterm birth in women with a history of previous caesarean in established labour.
- Conditions
- Preterm Birth, Preterm Premature Rupture of Membrane, Preterm Spontaneous Labor With Preterm Delivery
- Trial name
- CRAFT (NCT04110704)
- Testing
- Insertion of transvaginal cerclage
- Where
- United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Hysteroscopic Surgery, Pain, Postoperative
A Trial for Peroperative Procedure and Postoperative Pain After Rectal Misoprostol or Rectal Hyoscine Administration
Dilatation of the cervix is necessary before operative hysteroscopic procedures. This dilatation with Hegar dilators has certain difficulties and is associated with pain.
- Trial name
- NCT03359655
- Testing
- Misoprostol, Hyoscine butyl bromide
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Endothelial Dysfunction
Enhancing Parasympathetic Activity to Improve Endothelial Dysfunction, Vascular Oxidative Stress in African Americans
Specific Aim 1: To test the hypothesis that prolonged (3-month) treatment with galantamine inhibits NADPH IsoLG-protein adducts formation and improves markers of endothelial cell (EC) dysfunction in AAs.
- Trial name
- NCT04769206
- Testing
- Galantamine, TENS 7000
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Pregnancy
Pregnancy, Nitrate, Endothelial Function and Tissue Oxygen Saturation
Adequate macro and microvascular endothelial function during pregnancy is essential for the normal placental development and growing fetus.
- Trial name
- NCT03315806
- Testing
- Beetroot juice
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro