Clinical trials: Distension
Chronic Obstructive Pulmonary Disease (COPD), Inflammatory Disease
Endothelial Dysfunction in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD)
The purpose of the study is to determine a possible association between the clinical entity of exacerbation, markers of systemic inflammation and endothelial dysfunction in patients with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease (COPD), Inflammatory Disease, Endothelial Dysfunction
- Trial name
- EDAECOPD (NCT01460082)
- Where
- Austria
- Volunteers
- 29 people
- Sponsor
- LudwLudwig Boltzmann Institute for COPD and Respiratory Epidemiology
Endoscopic Papillary Balloon Dilation, Bile Duct Stones
Long-term Outcomes of Endoscopic Papillary Balloon Dilation for 8-12mm Bile Duct Stones: a Prospective Study
The investigators prospectively evaluated long-term outcomes of ELBPD+EST for CBD stones up to 8-12mm. EPBD+EST in patients with CBD stones up to 8-12mm appears to be associated with a very low (<3%) rate of long-term stone…
- Conditions
- Endoscopic Papillary Balloon Dilation, Bile Duct Stones, Endoscopic Sphincterotomy, Stone Recurrence
- Trial name
- NCT05191693
- Testing
- ERCP
- Where
- Greece
- Volunteers
- 72 people
- Sponsor
- Venizelio General Hospital
Crohn Disease
Evaluation of the Efficacy and Safety of Endoscopic Dilatation and Biological Therapy in Intestinal Stenosis Due to CD
All patients with Crohn\'s disease, already undergoing biological therapy for the treatment of clinically significant intestinal stenosis and/or already undergoing endoscopic balloon dilatation during the period January 2016…
- Trial name
- NCT06603298
- Where
- Italy
- Volunteers
- 182 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
End Stage Kidney Disease (ESRD)
Effect of the Amplifi™ Vein Dilation System on Outflow Vein Dilation and AV Fistula Maturation (AMPLIFI-1)
The AMPLIFI-1 Study is a prospective, multicenter pivotal clinical trial designed to evaluate the safety and effectiveness of the Amplifi™ Vein Dilation System in patients requiring distal arteriovenous fistula (AVF) creation for…
- Trial name
- AMPLIFI-1 (NCT07211035)
- Testing
- The Amplifi System is a temporary extracorporeal blood pump designed to deliver controlled flow through a peripheral vein for 24-72 hours prior to AVF creation., Standard of Care (AVF creation)
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- Amplifi Vascular, Inc.
Corneal Ectasia Disorders Including Keratoconus
The Effects of Corneal Collagen Cross-linking
The corneal collagen cross-linking treatment has been used with increasing success to treat corneal dystrophies such as "keratoconus." Recent advances have allowed different techniques for performing this cross-linking treatment.
- Trial name
- NCT01708538
- Testing
- CXL
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Rush Eye Associates
Cardiovascular Disease, Endothelial Dysfunction
Effect of Homocysteine-lowering Therapy With Folic Acid, Vitamin B12, and Vitamin B6 on Endothelium-dependent Vasodilatation of Forearm Resistance Vessels in Patients With Coronary Heart Disease
Endothelial dysfunction is an early marker of atherosclerosis and is found in patients (pts) with coronary (CAD) and peripheral artery disease (PAD).
- Trial name
- NCT00693589
- Testing
- folic acid, vitamin B12 and B6 and rosuvastatin
- Volunteers
- 36 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Stroke
MitoQ and Ischemic Conditioning To Assess Vascular Health Outcomes
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Trial name
- MITO (NCT06930638)
- Testing
- Ischemic Conditioning, Antioxidant Supplement
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical College of Wisconsin
Cervical Dilation
Self-Obtained Ultrasound Scans for Measurement of Cervical Dilation and Effacement in Labor
This is a pilot study to test the accuracy and comfort of self-directed ultrasound imaging of cervical dilation and effacement in pregnant women undergoing induction of labor.
- Trial name
- NCT05038891
- Testing
- Digital Cervical Exam, Transperineal Ultrasound, Transvaginal Ultrasound
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Crohn Disease, Stenosis
Long-term Study of Endoscopic Treatment of Stenosis in Crohn´s Disease
Stenosis is one of the most frequent complications in patients with Crohn's disease (CD), causing greater morbidity and increasing the probability of repeated surgery and short bowel syndrome.
- Trial name
- Long-ProtDilat (NCT06036680)
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital Mutua de Terrassa
Keratoconus
Eye Rubbing and Keratoconus in Montpellier CHU
Evaluate the illness experience of patients with keratoconus as well as the rubbing habits of this population compared to the general population.
- Trial name
- Rub'Cornea (NCT04249180)
- Where
- France
- Sponsor
- University Hospital, Montpellier
Cervical Dilation, Induction of Labor
Ultrasound Assessment of DILAPAN-S
The goal of this observational prospective study is to assess the change in Dilapan-S rod diameters using transvaginal ultrasound over a period of 12 hours in term women undergoing induction of labor.
- Conditions
- Cervical Dilation, Induction of Labor, Ultrasound Evaluation
- Trial name
- NCT04529837
- Testing
- Gauze, No gauze
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Eastern Virginia Medical School
Eustachian Tube Dysfunction
XprESS ET Registry
A prospective, multicenter, registry of patients undergoing balloon dilation of the Eustachian tubes (ET).
- Trial name
- NCT04136977
- Testing
- Eustachian tube dilation
- Where
- 11 sites in United States
- Volunteers
- 169 people
- Sponsor
- Entellus Medical, Inc.
Hemorrhage
Uterotonic Prophylaxis Trial
Excessive bleeding after dilation and evacuation (D\&E) requiring interventions is common, occurring in approximately 30% of cases at one large abortion-providing clinic.
- Trial name
- UPT (NCT02408965)
- Testing
- Methergine
- Where
- United States
- Volunteers
- 284 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Keratoconus, Ectasia
UVA-Riboflavin Crosslinking Treatment of Corneal Ectasia
The primary objective of this study is to evaluate two different ultraviolet (UV) dosing regimens for corneal collagen cross linking to slow the progressive changes in corneal curvature in eyes with progressive keratoconus or…
- Conditions
- Keratoconus, Ectasia, Corneal Ectasia
- Trial name
- NCT01325298
- Testing
- UV-X Light, Riboflavin
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mercy Center for Corrective Eye Surgery
Coronary Arteriosclerosis
Scoreflex TRIO - Scoring PTCA Catheter
To evaluate the acute safety and device procedural success of the Scoreflex TRIO Scoring PTCA catheters versus Scoreflex NC Scoring PTCA catheters in subjects with stenotic coronary arteries during percutaneous coronary…
- Trial name
- NCT05929313
- Testing
- OrbusNeich Scoreflex TRIO, OrbusNeich Scoreflex NC
- Where
- 4 sites in China
- Volunteers
- 210 people
- Sponsor
- OrbusNeich
Eustachian Tube Dysfunction
Balloon Dilation of the Eustachian Tube
In this study, patients with dysfunction of the eustachian tube will be included. They will be randomized to one of two treatment groups. 1. balloon dilation of the eustachian tube or 2.
- Trial name
- BDET (NCT05270031)
- Testing
- Balloon dilation of the eustachian tube
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Polycystic Ovary Syndrome, Endothelial Dysfunction
Metformin+ Drospirenone/ethinylestradiol30µg and Flow-mediated Dilation in Polycystic Ovary Syndrome
The purpose of this study is to assess the effects of ethinylestradiol 30µg-drospirenone combined with metformin and weight loss by means of dietary intervention on the indices of endothelial dysfunction (i.e.
- Trial name
- NCT01459445
- Testing
- Metformin, Ethinylestradiol 30µg-Drospirenone
- Where
- Romania
- Volunteers
- 26 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
FURS, Ureteral Dilatation
Pre-Op Sildosine and Ureteral Dilation During F-URS
We proposed that silodosin administration preoperatively may facilitate ureteral access sheath (UAS) placement prior to flexible ureteroscopy (F-URS) and decrease the incidence of ureteric injury in some difficult cases.
- Conditions
- FURS, Ureteral Dilatation, Sildosine
- Trial name
- NCT05798572
- Testing
- Sildosin group
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Benha University
Gastric Dilation, Bowel Distention
Effect of Mask Ventilation on Surgical Field View in Robotic Colorectal Surgery
The goal of this clinical trial is to demonstrate the effects of pressure-controlled mask ventilation and non-mask ventilation during anaesthesia induction on gastric insufflation, gastric dilatation, increased bowel movements…
- Conditions
- Gastric Dilation, Bowel Distention, Surgical Procedure, Unspecified
- Trial name
- NCT07097129
- Testing
- Mask Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Koç University
Aortic Valve Stenosis
Ascending Aortic Dilation in BiAV After TAVR
This study sought to evaluate changes in ascending aorta size after transcatheter aortic valve replacement (TAVR) in patients with bicuspid aortic valve (BiAV) compared with patients with tricuspid aortic valve (TAV).
- Trial name
- NCT03051334
- Testing
- diagnosed as bicuspid aortic valve
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital