Clinical trials: Distension
Carotid Artery Stenosis
Evaluation of the 3-in-1 Neuroguard IEP System for Carotid Artery Stenosis
The Neuroguard IEP System is a 3-in-1 carotid stent delivery system consisting of an angioplasty balloon, an integrated embolic protection device and a nitinol self-expanding stent loaded over the balloon and constrained by an…
- Trial name
- PERFORMANCE (NCT04142541)
- Testing
- Neuroguard® IEP 3-in-1 Carotid Stent and Post-Dilation Balloon System with Integrated Embolic Protection (Neuroguard IEP System)
- Where
- 6 sites in Germany, Italy
- Volunteers
- 67 people
- Sponsor
- Contego Medical, Inc.
Smoking Cessation, Brachial Flow Mediated Dilatation
Smoking Cessation in a Cohort HIV+ Rio de Janeiro, Brazil.
The study was carried out within a large, urban prospective cohort of PLHIV at the Instituto Nacional de Infectologia Evandro Chagas (INI).
- Conditions
- Smoking Cessation, Brachial Flow Mediated Dilatation, Nicotine Replacement Therapy
- Trial name
- NCT05873738
- Testing
- Nicotine replacement
- Where
- Brazil
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Instituto Fernandes Figueira
Insulin Sensitivity, Flow-mediated Dilation
Vascular Function, Insulin Sensitivity, and Vitamin D
The overall objectives of this study are to examine the relationships between circulating vitamin D, insulin sensitivity, and multiple indices of vascular function and to examine whether vitamin D deficiency in African Americans…
- Conditions
- Insulin Sensitivity, Flow-mediated Dilation, Arterial Stiffness
- Trial name
- VIVID (NCT01041547)
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Cornea; Ectasia, Refractive Errors
Corneal Elastography and Patient Specific Modeling
The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors.
- Conditions
- Cornea; Ectasia, Refractive Errors, Keratoconus
- Trial name
- NCT03030755
- Testing
- Optical coherence tomography
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Peripheral Artery Disease
Lutonix Global SFA Registry
The registry will enroll patients with claudication or ischemic rest pain and an angiographically significant lesion in the superficial femoral or popliteal artery.
- Trial name
- NCT01864278
- Testing
- Lutonix Drug Coated Balloon
- Where
- 23 sites in Austria, Belgium and 8 more
- Volunteers
- 691 people
- Sponsor
- C. R. Bard
Cardiovascular Diseases, Vascular Dilation
Chardonnay Marc and Vascular Response
This study aims to obtain data on the potential influence of Vine to Bar product(s) containing Chardonnay marc on cardiometabolic health.
- Conditions
- Cardiovascular Diseases, Vascular Dilation, Oxidative Stress
- Trial name
- NCT05545865
- Testing
- Low Flavanol Cocoa Powder, High Flavanol Cocoa Powder, Vine to Bar Chocolate - 2 servings
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Crohn Disease
Endoscopic Balloon Dilatation Combined With PRP Injection in Colonic Stenosis in Crohn's Disease
The aim was to investigate whether endoscopic balloon dilatation combined with PRP injection can help prevent or prolong restenosis in patients with Crohn's disease with colonic stenosis, and to explore the concentration of PRP.
- Trial name
- NCT06165289
- Testing
- PRP Injection
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Intracranial Atherosclerotic Stenosis
Clinical Trial of Biolimus-coated Intracranial Balloon Dilation Catheter
This test took the target lesion restenosis rate 6 months after the operation as the main endpoint to verify the effectiveness of the intracranial balloon expansion catheter of Biolimus coating.
- Trial name
- NCT06140550
- Testing
- Drug balloon dilated, balloon dilated
- Volunteers
- 204 people
- Sponsor
- Bochang
Colonoscopy, Pain, Abdominal
The Effect of Abdominal Massage on Pain and Distention After Colonoscopy
Aim: This study aimed to evaluate the effect of abdominal massage on pain and distention in patients who underwent colonoscopy. Methods: This randomized controlled study was conducted between October 2019 and December 2021 with…
- Conditions
- Colonoscopy, Pain, Abdominal, Massage, Distension; Bowel
- Trial name
- NCT05823350
- Testing
- Abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Ectasia
Eye Rubbing and Transient Change in Corneal Parameters
This study addresses the research question: How does eye rubbing affect corneal (clear part of eye) parameters in healthy volunteers The study objectives are: 1. To determine the corneal changes following eye rubbing 2.
- Trial name
- NCT02131740
- Testing
- Eye rubbing, No eye rubbing
- Where
- United Kingdom
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Sussex Eye Hospital
Nasolacrimal Duct Obstruction
Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years Old
The purpose of this study is: To report the success proportions for the treatment of persistent nasolacrimal duct obstruction for three surgical procedures: balloon catheter dilation, nasolacrimal intubation, and simple probing.
- Trial name
- NLD2 (NCT00315315)
- Testing
- Nasolacrimal balloon catheter dilation, Nasolacrimal intubation, Nasolacrimal duct probing
- Where
- 2 sites in United States
- Volunteers
- 194 people
- Sponsor
- Jaeb Center for Health Research
Mydriasis, Dilation
Safety and Efficacy of Ophthalmic Phentolamine Mesylate to Reverse Pharmacologically Induced Mydriasis
The objectives of this study are: To evaluate the efficacy of Nyxol (phentolamine mesylate ophthalmic solution 1%) to expedite the reversal of pharmacologic mydriasis To evaluate the safety of Nyxol To evaluate the effect of…
- Trial name
- NCT04024891
- Testing
- Phentolamine Mesylate Ophthalmic Solution 1%
- Where
- 4 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Opus Genetics, Inc
Acute Myocardial Infarction, Restenoses, Coronary
Abbott Vascular Medical Device Registry
The AV-MDR is a prospective, non-randomized, open-label, multi-center registry. The purpose of the AV-MDR study is to proactively collect and evaluate clinical data on the usage of the devices in scope within their intended use…
- Conditions
- Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism
- Trial name
- AV-MDR (NCT04573660)
- Testing
- Coronary and peripheral stents, Pacing catheters, Vascular plugs
- Where
- 37 sites in United States, Australia and 12 more
- Volunteers
- 3,784 people
- Sponsor
- Abbott Medical Devices
Healthy
Effect of Abdominal Wall Activity on the Responses to Meal Ingestion
Meal ingestion induces sensations that are influenced by a series of conditioning factors. Aim: to determine the effect of abdominal wall activity on the responses to a standard probe meal.
- Trial name
- NCT04691882
- Testing
- Diaphragmatic contraction, Diaphagmatic relaxation
- Where
- Spain
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Bronchiolectasis
PEP Breathing Versus Incentive Spirometry on Dyspnea and Sputum Profile in Bronchiolectasis Patients
Bronchiolectasis is the manifestation of chronic bronchitis characterized by saccular dilatation of the terminal bronchioles \& bronchiectasis refers to abnormal dilatation of the bronchi.
- Trial name
- NCT05719597
- Testing
- PEP (Positive Expiratory Pressure), IS (Incentive spirometry)
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
Keratoconus, Corneal Ectasia
Safety & Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus or Corneal Ectasia After Refractive Surgery
The objectives of this study are to evaluate and compare the safety and efficacy of three treatment regimens for corneal collagen cross-linking performed with VibeX (riboflavin ophthalmic solution) and the KXL System in impeding…
- Trial name
- NCT01459679
- Testing
- KXL System (15 mW/cm2), KXL System (30 mW/cm2), KXL System (45 mW/cm2)
- Where
- 83 sites in United States, Puerto Rico
- Volunteers
- 1,721 people
- Sponsor
- American-European Congress of Ophthalmic Surgery
Interstitial Cystitis, Painful Bladder Syndrome
Bladder Thermal Distention for Patients With Interstitial Cystitis / Painful Bladder Syndrome
Patients with Interstitial Cystitis / PBS will be treated with bladder thermal distention (BTD).
- Trial name
- IC (NCT01838486)
- Testing
- Bladder Thermal Distention
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf-Harofeh Medical Center
Mydriasis
Safety and Efficacy of Fixed Combination Phenylephrine-Tropicamide for Pupil Dilation
Subjects will receive ½ of the approved dose of MydCombi to determine the dilation curve with the reduced dose.
- Trial name
- NCT06217796
- Testing
- MydCombi
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Eyenovia Inc.
Coronary Ectasia, Microbial Disease
The Relationship Between Microbiota and Coronary Ectasia
Introduction: It is now known that the microbiota is far beyond the microbial communities living in certain parts of our body and functions like a metabolic organ.
- Trial name
- NCT06384703
- Testing
- Taking blood for kit study
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Konya Beyhekim Training and Research Hospital
Endothelial Function
Dose-dependent Effects of Blueberry Polyphenols on Endothelial Function in Healthy Individuals
The purpose of this study is to assess the impact of acute blueberry polyphenol intake on endothelial function of healthy volunteers.
- Trial name
- BB2 (NCT01829542)
- Testing
- Freeze-dried blueberry powder dissolved in water, Control
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Reading