Clinical trials: Distress
Psychological Distress, Depression
Ensuring Quality in Psychological Support
The goal of this project is to test tools that will be part of a platform for training and supervision of mental health and psychosocial support helpers, including providers without specialized training in mental health.
- Trial name
- EQUIP (NCT04704362)
- Testing
- Ensuring Quality in Psychological Support, Standard Training and Supervision
- Where
- 7 sites in Ethiopia, Jordan and 5 more
- Volunteers
- 896 people, healthy volunteers welcome
- Sponsor
- George Washington University
Fetal Distress, Fetal Hypoxia
Application of Electronic Endoscope in Fetal Distress
Fetal distress is a common emergency in obstetrics, which refers to the combined symptoms of fetal health and life in utero due to acute or chronic hypoxia, with an incidence of 2.7% to 38.5%.
- Trial name
- NCT06608654
- Testing
- endoscope application
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
COVID-19 Pneumonia, Bromelains Adverse Reaction
Nebulised BromAc in Healthy Volunteers
COVID-19 is a disease that has multiple facets including an inflammatory storm, it promotes blood clotting and causes kidney damage, mucinous secretions in the lung are of great importance to outcome.
- Conditions
- COVID-19 Pneumonia, Bromelains Adverse Reaction, Acetylcysteine Adverse Reaction, Mucus; Plug
- Trial name
- NCT05220605
- Testing
- BromAc
- Where
- Australia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Mucpharm Pty Ltd
Cancer, Psychological Distress
Assessment Psychological Distress for Cancer Heredity Test
The study of hereditary cancer related syndromes allows reducing the risk of suffering in cancer to patients and close relatives.
- Conditions
- Cancer, Psychological Distress, Hereditary Diseases, Genetic Counseling
- Trial name
- NCT04428710
- Testing
- assessment with psychometric questionnaire
- Where
- Spain
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Fe
Oxygen Inhalation Therapy, Labour
Maternal Oxygen Administration for Fetal Distress II
Supplementary oxygen is routinely administered to patients, even those with adequate oxygen saturations, in the belief that it increases oxygen delivery.
- Conditions
- Oxygen Inhalation Therapy, Labour, Fetal Distress
- Trial name
- NCT03764696
- Testing
- tight-fitting simple facemask
- Where
- 3 sites in China
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Navy General Hospital, Beijing
Stress Disorders, Post-Traumatic
Identifying Toddlers and Their Parents Who Are Suffering From Posttraumatic Distress Following War and Terror
The project is aimed at identifying children who are suffering from posttraumatic distress and increasing capacity to provide treatment for them and for their caretakers.
- Trial name
- NCT00600418
- Where
- Israel
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Herzog Hospital
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Comparing Telephone Symptom Monitoring Interventions for Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment
In this clinical trial, symptom monitoring (interactive voice response [IVR] is compared to automated telephone symptom management [ATSM] and telephone interpersonal counseling [TIPC]) for reducing symptom burden and…
- Trial name
- SYMON (NCT06279013)
- Testing
- Counseling, Health Education, Interview
- Where
- 34 sites in United States, Puerto Rico
- Volunteers
- 486 people, healthy volunteers welcome
- Sponsor
- NRG Oncology
HIV - Human Immunodeficiency Virus, Psychological Distress
Comparison of Acceptance and Commitment Therapy and Cognitive Behavior Therapy: Managing Psychological Distress and Its Multifaceted Impact on Stigmatization, Psychological Wellbeing, Social Support and Treatment Adherence in HIV/AIDS Patients
This is a randomized controlled trial comparing Acceptance and Commitment Therapy (ACT) and Cognitive Behavioral Therapy (CBT) for HIV/AIDS patients at Sheikh Zayed Hospital.
- Trial name
- HIV CBT ACT (NCT07652918)
- Testing
- CBT, ACT+ Standard Care
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sadia Batool
Burnout, Professional, Anxiety
Occupational Distress in Doctors: The Effect of an Induction Programme
Background: Over 39% of approximately 3,000 doctors (The British Medical Association quarterly survey, 2015) admitted to frequently feeling drained, exhausted, overloaded, tired, low and lacking energy.
- Conditions
- Burnout, Professional, Anxiety, Grief, Adaptation, Psychological
- Trial name
- NCT02838290
- Testing
- Induction, Control group
- Volunteers
- 232 people, healthy volunteers welcome
- Sponsor
- Birkbeck, University of London
Emotional Distress
Mechanisms of Mindfulness Intervention：Rumination Behavioral Experiments
This study hopes to explore whether the changes in rumination exhibited in behavioral experiments mediates the effects of mindfulness intervention on alleviating emotional distress
- Trial name
- NCT06722573
- Testing
- Mindfulness Intervention for Emotional Distress(MIED)-normal version
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Peking University
Depressive Symptoms, Psychological Distress
Internet-based Intervention for Enhancing the Psychological Well-being of Elderly Caregivers
This study will examine whether an Internet-based Acceptance and Commitment Therapy (ACT) intervention is effective, firstly, on reducing depressive symptoms, and, secondly, on improving well-being of elderly family caregivers.
- Conditions
- Depressive Symptoms, Psychological Distress, Quality of Life
- Trial name
- CareACT (NCT03391596)
- Testing
- Internet-based ACT intervention, Standardized rehabilitation, Support by voluntary caregiver associations
- Where
- Finland
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- The Gerocenter Foundation for Research and Development
Acute Respiratory Distress Syndrome, Pneumonia in Children
AI-Guided Mechanical Ventilation in Children: A Randomized Controlled Trial
This prospective, randomized controlled trial aims to evaluate whether an AI-driven decision support system can improve clinical outcomes for mechanically ventilated pediatric patients (aged 1 month to 18 years) in the PICU…
- Conditions
- Acute Respiratory Distress Syndrome, Pneumonia in Children, Respiratory Failure (Pediatric Patients), Congenital Heart Disease in Children
- Trial name
- NCT07728136
- Testing
- AI-generated recommendations for ventilator parameters.
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Wu Rongzhou
Psychological Distress, Post Partum Depression
Impact of Mothers Touch Program on Women's Psychological Functioning
The study investigates the effect of the Mothers Touch program on the psychological well-being of new mothers following 5 weeks of child birth.
- Conditions
- Psychological Distress, Post Partum Depression, Mood
- Trial name
- NCT03703219
- Testing
- Mothers Touch Program
- Where
- India
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Psychological Distress
The Together Webinar Programme For Military Partners
Military partners are at risk of mental health difficulties, including depression, anxiety and secondary traumatization. However, many partners face a range of barriers in accessing psychological support.
- Trial name
- TTP-Webinar (NCT05013398)
- Testing
- The Together Webinar Programme
- Where
- United Kingdom
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Combat Stress
Anxiety, Distress
Using Virtual Reality Simulation to Prepare Children Undergoing MRI
This study will evaluate the effectiveness of using virtual reality (VR) to reduce distress in pediatric patients undergoing MRI scans compared to other methods of preparation. Children will be divided into four groups.
- Trial name
- NCT04402216
- Testing
- Child Life-led preparation, MRI preparation video, KindVR Virtual Reality MRI Preparation Experience
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Colorado
Transient Tachypnea of the Newborn, Neonatal Respiratory Distress
Efficacy of Misoprostol in Prevention of Neonatal Respiratory Morbidity in Parturient at Early Term Elective Caesarian Section
Neonatal respiratory morbidities represent a common group of post natal complications including respiratory distress syndrome, transient tachypnea of newborn, and persistent pulmonary hypertension of newborn.
- Trial name
- NCT04780412
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Psychological Distress, Trauma, Psychological
Feasibility Study of a Group Intervention for Youth Wellbeing
Psychological distress, anxiety and depression are common in adolescence, and even more so following traumatic events. On Friday 15 March 2019, two mosques in Ōtautahi, Christchurch were targeted in an act of terrorism, resulting…
- Conditions
- Psychological Distress, Trauma, Psychological, Emotional Problem
- Trial name
- NCT05030909
- Testing
- transdiagnostic group treatment
- Where
- New Zealand
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Otago
Parenting, Self Efficacy
The Development and Evaluation of a Web-based Childbirth and Parenting Intervention Program
Background: The transition to parenthood is stressful for first-time mothers and fathers and links to adverse health outcomes. Despite Internet use's popularity, an effective web-based, individually-tailored intervention to…
- Conditions
- Parenting, Self Efficacy, Psychological Distress
- Trial name
- NCT04981730
- Testing
- Web-based intervention
- Where
- Taiwan
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Neonatal Respiratory Distress
In-person Versus Online Debriefing in HBB
The objective of this study is to assess the effectiveness of online formative feedback and debriefing on nursing and medical students enrolled in the HBB course in comparison to traditional face-to-face feedback.
- Trial name
- NCT05257499
- Testing
- On line debriefing
- Where
- 2 sites in Lebanon
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Long-COVID, Post-COVID
ASAP - Assisted Immediate Augmented Post-/Long-COVID Plan for Patients Infected With COVID-19
Post-/long-COVID occurs in patients with severe, moderate, and even mild courses. The symptomatology is multi-layered and complex.
- Conditions
- Long-COVID, Post-COVID, Psychosomatic Disorder, Psychological Distress
- Trial name
- ASAP (NCT05238415)
- Testing
- Psychological and Physiological Assessments
- Where
- Germany
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Prof. Dr. Sonia Lippke