Clinical trials: Distress
Tinnitus, Distress, Emotional
Internet-delivered Psychological Interventions for Tinnitus
Tinnitus can be very distressing for some individuals who experience it. The most studied intervention that works well for tinnitus distress is cognitive behavioral therapy (CBT).
- Conditions
- Tinnitus, Distress, Emotional, Depression, Anxiety, Sleep
- Trial name
- TinnitusLT (NCT05705323)
- Testing
- Internet-delivered cognitive behavioral therapy (iCBT), Internet-delivered mindfulness-based tinnitus stress reduction (iMBTSR)
- Where
- Lithuania
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Depression - Major Depressive Disorder, Psychological Distress
Testing a Non-Deceptive Placebo Intervention for Subclinical Depressive Symptoms
Subclinical depression - depressive symptoms that fall below the threshold for major depressive disorder - is common in young adults and predicts later depressive episodes, yet it often goes untreated.
- Conditions
- Depression - Major Depressive Disorder, Psychological Distress, Depression / Major Depressive Disorder
- Trial name
- NDP_CCG (NCT07889908)
- Where
- United States
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Miami University
Acute Lung Injury (ALI), Acute Respiratory Distress Syndrome (ARDS)
Effect of R-spondin3 on Sepsis Induced Endothelial Dysfunction
Sepsis is the most frequent risk factor for ALI/ARDS. Meanwhile, Pulmonary is the most vulnerable organ to fail in response to sepsis, vascular endothelial dysfunction is a central event in the pathophysiology of sepsis.
- Trial name
- NCT04546919
- Testing
- sepsis
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Virus Diseases, Pneumonia
Universal Anti-Viral Vaccine for Healthy Elderly Adults
This protocol tests the safety and efficacy of a novel universal vaccine concept called "allo-priming" which is designed to protect elderly adults from progression of any type of viral infection, including possible protection…
- Conditions
- Virus Diseases, Pneumonia, COVID-19 Respiratory Infection, RSV Pneumonia
- Trial name
- ALLOPRIME (NCT04441047)
- Testing
- AlloStim
- Where
- 4 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mirror Biologics, Inc.
Psychological Distress, Psychological Well-being
Two Sessions of Coach-Delivered Core Transformation for Distress and Well-Being
The goal of this study is to learn if Core Transformation, a guided coaching process, lowers psychological distress in adults. It will also look at well-being, daily functioning, and whether any changes last over time.
- Trial name
- NCT07879196
- Testing
- Core Transformation Process
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- Andreas NLP (Legal Entity - Real People Press)
Primary Dysmenorrhea, Menstrual Pain
The Effectiveness of an Intervention of Fresh Strawberries on Menstrual Pain and Menstrual Distress
The purpose of this project is to know the effectiveness of an intervention based on the consumption of fresh strawberries from the Huelva region on menstrual pain and menstrual distress in young university students with primary…
- Conditions
- Primary Dysmenorrhea, Menstrual Pain, Menstrual Distress \(Dysmenorrhea\)
- Trial name
- NCT06250660
- Testing
- Strawberry Intervention
- Where
- Spain
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Cynthia del Rocío Márquez Beltrán
Fetal Distress
Evaluation of Fetal Cardiac Function in Rheumatic Heart Disease (RHD) Patients
The goal of this study is to evaluate fetal myocardial performance in patients with heart diseases in comparison to normal pregnant patients.
- Trial name
- RHD (NCT03095937)
- Where
- Egypt
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Assiut University
Anxiety, Fetal Distress
Music Therapy on High Risk Pregnant Women of Non-Stress Test
Non-stress testing (NST) is one of the most commonly used methods to assess fetal health in the prenatal period because it is an easily interpreted, non-invasive, painless, and short-term diagnostic method.
- Conditions
- Anxiety, Fetal Distress, Music
- Trial name
- NCT04986475
- Testing
- Music Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Orthopaedic Surgery
An mHealth Self-Management Program to Decrease Postoperative Symptom Distress
The purposes of this study are to determine if use of the Postoperative Care at Home (PoCAH) tailored self-management program delivered via mobile technology (a mobile app) after discharge to home will result in: 1) fewer and/or…
- Trial name
- NCT02610894
- Testing
- mHealth application (PoCAH), As usual standard discharge and care instructions
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Jan Odom Forren
Counseling
The Effect of Mindfulness-based Sexual Counseling on Sexual Distress in Pregnant Women
The study was conducted in order to determine the effect of mindfulness-based sexual counseling on sexual distress, attitude towards sexuality and body image concerns in pregnant women.
- Trial name
- NCT04900194
- Testing
- mindfulness-based sexual counseling
- Where
- Turkey (Türkiye)
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Inonu University
Post Traumatic Stress Disorder, Insomnia
RESILIENT - An Online Multidimensional Treatment to Promote Resilience After a Disaster: Randomized Controlled Trial Protocol
Background. The wildfires on May 1, 2016 in Fort McMurray, Alberta (Canada), destroyed approximately 2,400 homes and buildings and led to massive displacement of approximately 88,000 people.
- Conditions
- Post Traumatic Stress Disorder, Insomnia, Depression
- Trial name
- RESILIENT (NCT04808713)
- Testing
- Treatment
- Where
- Canada
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Laval University
Survival, Prosthesis, Oxygen Deficiency
Awake Prone Positioning for COVID-19 Acute Hypoxaemic Respiratory Failure
The objective of our study is to evaluate the effectiveness of prone position in preventing intubation or death in spontaneously ventilated patients with COVID-19 with acute respiratory failure.
- Trial name
- NCT05866289
- Testing
- Prone position
- Where
- Morocco
- Volunteers
- 1,069 people, healthy volunteers welcome
- Sponsor
- Mohammed VI University Hospital
Psychological Distress, Stress, Psychological
The Effect of Psychoeducation Based on NSM on the Psychological Distress and Coping of the Spouses of Patients in ICU
The aim of action research this study is to examine the effect of psychoeducation based on Neuman's Systems Model on psychological distress and coping with the stress of spouses of patients in the intensive care unit.
- Trial name
- NCT06243523
- Testing
- The stress management psychoeducation program based on Neuman's Systems Model
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Respiratory Distress, Newborn
Effectiveness of HVNI in Preterm Infants With Moderate Respiratory Distress
Neonatal respiratory distress is a common problem in preterm infants. The application of CPAP is widely used in neonatal units as a primary mode of respiratory support for respiratory distress.
- Trial name
- NCT06436222
- Testing
- HVNI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Suicide, Distress, Emotional
Surveillance of Suicide Ideation in Adolescents (VISIA)
The goal of this observational study is to validate an AI algorithm's capability to differentiate the population with suicidal ideation from a control population using various multimodal variables, including voice analysis…
- Conditions
- Suicide, Distress, Emotional, Adolescent Behavior, Healthy
- Trial name
- VISIA (NCT06341634)
- Where
- 4 sites in Spain
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- Servicio Gallego de Salud
Emotional Resilience
A Network Analysis on the Role of Specific ER Abilities as ERFs for Distress and Mental Health, in Relation to CAs Exposure in the AYAs
This activity will aim to compare the network of emotional resilience factors and stress in adolescents and young adults depending on the childhood abuse exposure (considered moderator), using a network analysis approach.
- Trial name
- NCT06986928
- Testing
- No intervention will be applied.
- Where
- Romania
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Psychological Distress, Bonding
The Effects of Listening to Lullabies and Self-selected Music on Distress and Maternal Attachment in Pregnant Women
The purpose of this study is to compare the effects of listening to lullabies and self-selected music at home in reducing the distress experienced in the prenatal period and increasing maternal attachment in pregnant women.
- Trial name
- NCT05228392
- Testing
- listening to music
- Where
- Turkey (Türkiye)
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
COVID-19 Acute Respiratory Distress Syndrome, Pregnancy Related
Melatonin Levels on COVID-19 Positive Pregnant Women
This study aimed to investigate the prognostic value of serum melatonin as a biomarker for the determination of severe COVID-19 infection in pregnant women.
- Conditions
- COVID-19 Acute Respiratory Distress Syndrome, Pregnancy Related, Pregnancy Complications
- Trial name
- NCT05318144
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Nazan Yurtcu MD
Alzheimer Disease, Mild Memory Disturbance
The MObile AssessMENT of Behavioral and Psychological Symptoms of Dementia in Amnestic MCI and AD (MOMENT) Study
The purpose of this research study is to learn whether it is possible and useful for caregivers to report behavioral or psychological symptoms of people with mild memory problems or Alzheimer's disease through a smartphone mobile…
- Conditions
- Alzheimer Disease, Mild Memory Disturbance, Mild Cognitive Impairment
- Trial name
- MOMENT (NCT04482036)
- Testing
- Mobile Phone Application Assessments, Standard Assessments
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Indiana University
Pregnancy, Respiratory Distress Syndrome
Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial
This is a randomized placebo controlled trial to evaluate whether antenatal corticosteroids can decrease the rate of neonatal respiratory support, thus decreasing the rate of NICU admissions and improving short-term outcomes in…
- Conditions
- Pregnancy, Respiratory Distress Syndrome, Pregnancy Outcomes, Preterm Birth
- Trial name
- ALPS (NCT01222247)
- Testing
- Betamethasone
- Where
- 17 sites in United States
- Volunteers
- 2,831 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center