Clinical trials: Disturbed Sleep
Sleep, Sleep Disturbance
Radicle Rest 24: A Study of Health and Wellness Products on Sleep and Related Health Outcomes
A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on sleep and related health outcomes.
- Conditions
- Sleep, Sleep Disturbance, Sleep Disorder
- Trial name
- NCT06347744
- Testing
- Radicle Rest Active Study Product 1.1 Usage, Radicle Rest Active Study Product 2.1 Usage
- Where
- United States
- Volunteers
- 1,646 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Hot Flashes
A Mobile App for Hot Flashes and Sleep Disturbances
The purpose of the study is to compare the possible efficacy and acceptability of two mobile health applications for the reduction of hot flashes and related symptoms.This study is completely remote, and participants will be be…
- Trial name
- NCT06718803
- Testing
- Hypnosis, Structured Attention
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Baylor University
Sleep Disturbance, Depression
The Effects of Bright Light Therapy on Adolescent's Sleep Quality and Well-being
Sleep problems are common among adolescents which can have a variety of serious biological, emotional, cognitive and psychological consequences.
- Conditions
- Sleep Disturbance, Depression, Mood, Circadian Rhythms
- Trial name
- NCT05555186
- Testing
- BWL classrooms (Experimental), DWL classrooms (Comparison)
- Where
- Iceland
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Perceived Stress, Anxiety
Effects of Mobile App in House Staff Health and Well-being During COVID-19 Pandemic
Due to the COVID-19 global health pandemic, many people are likely experiencing increased stress. The well-being of physicians in training may be significantly impacted by this pandemic.
- Conditions
- Perceived Stress, Anxiety, Sleep Disturbance, Burnout
- Trial name
- NCT04374786
- Testing
- Calm Meditation App
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Schizophrenia, Insomnia Related to Schizophrenia (307.42)
Sodium Oxybate in Schizophrenia With Insomnia
The present protocol proposes study of the recently approved compound sodium oxybate (Xyrem), a gamma-aminobutyric acid type b (GABAB) and a g-hydroxybutyric acid (GHB) receptor agonist, for the study of persistent symptoms of…
- Trial name
- NCT00594256
- Testing
- Sodium Oxybate
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Nathan Kline Institute for Psychiatric Research
Sleep Disturbance, Total Joint Arthroplasty
Randomized Trial Investigating Melatonin Supplementation vs Placebo on Sleep Disturbance Following Total Joint Arthroplasty
The purpose of this study is to determine whether melatonin when used as a supplement after surgery improves sleep following total joint arthroplasty
- Trial name
- NCT04590742
- Testing
- melatonin 6mg
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Sleep Disturbance, Postmenopausal Symptoms
Effect of Sleep Restriction on Adipose Tissue and Skeletal Muscle Insulin Sensitivity
Inadequate sleep is an independent risk factor for metabolic abnormalities (such as obesity, insulin resistance, and hyperglycemia).
- Conditions
- Sleep Disturbance, Postmenopausal Symptoms, Insulin Sensitivity, Cardiovascular Risk Factor
- Trial name
- SLEEP-IN (NCT04286451)
- Testing
- Sleep Restriction, Habitual Sleep
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Breast Cancer, Depression
The Effect of Melatonin on Depression, Anxiety, Cognitive Function and Sleep Disturbances in Breast Cancer Patients
The purpose of this study is to investigate the effect of 6 mg melatonin daily for 1 week preoperatively to 12 weeks postoperatively on depressive symptoms, anxiety, cognitive function and sleep disturbances in breast cancer…
- Trial name
- MELODY (NCT01355523)
- Testing
- Melatonin (N-acetyl-5-methoxytryptamine)
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- Melissa Voigt Hansen
Total Knee Arthroplasty (TKA)
Effect of Preoperative Sleep Disturbance on Postoperative Pain and Recovery
The study subjects consisted of patients who underwent elective total knee arthroplasty (TKA) at Gansu Provincial Hospital of TCM from November 2023 to January 2024.
- Trial name
- NCT06815744
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Gansu Provincial Hospital
Parkinson Disease, Sleep Disturbance
Lighting Intervention to Improve Sleep
50 participants with Parkinson's disease will be recruited to complete actigraphy studies to assess sleep disturbances. For this, participants will wear an Actigraph for seven days.
- Trial name
- NCT05757414
- Testing
- Tailored Lighting Intervention (LIT), Actigraph
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Sleep Initiation and Maintenance Disorders
Effects of Valerian on Sleep in Healthy Older Adults
The purpose of this study is to examine the way valerian, an herbal sleep agent, is absorbed and distributed in the body. This study will also compare the effects of valerian after 1 week versus after 2 weeks.
- Trial name
- NCT00097604
- Testing
- Valerian root extract
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Washington
Sleep Disturbance, Arthropathy
The Effect of Mindfulness Training Before Primary Total Joint Arthroplasty on Sleep Quality
The primary purpose of this study is the determine whether a 15 minute Mindfulness Meditation (MM) administered at the preoperative appointment prior to primary unilateral total joint arthroplasty (TJA) results in any improvement…
- Trial name
- NCT05295004
- Testing
- Mindfulness Meditation Training
- Where
- United States
- Volunteers
- 282 people
- Sponsor
- Colorado Joint Replacement
Chronic Fatigue Syndrome, Myalgic Encephalomyelitis
Melatonin and Zinc Administration on Cardinal Symptoms in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
The aim of the study is to investigate the effects of oral melatonin and zinc supplementation on core features in individuals with ME/CFS
- Trial name
- MelatoZincME (NCT05454683)
- Testing
- melatonin plus zinc, isomaltose and magnesium stearate
- Where
- Spain
- Volunteers
- 106 people
- Sponsor
- Laboratorios Viñas, S.A.
Anxiety, Sleep Disturbance
Effects of Peer Support and Progressive Relaxation Exercises on Sleep Quality and Anxiety
The effect of peer support and progressive relaxation exercise programs on midwifery students' sleep and anxiety levels in the COVID-19 pandemic was investigated in the present research.
- Trial name
- NCT05570773
- Testing
- peer support program
- Where
- Turkey (Türkiye)
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Chronic Widespread Pain, Sleep Disturbance
Sleep Disturbances and Chronic Widespread Pain
Chronic widespread pain (CWP), defined as long-lasting pain in multiple body regions, has a prevalence of 10-14% in Europe and is associated with other physical symptoms such as fatigue and cognitive problems.
- Trial name
- POSEIDON (NCT03908905)
- Testing
- Polysomnography
- Where
- Sweden
- Volunteers
- 96 people
- Sponsor
- Uppsala University
Sleep Apnea, Sleep Disturbance
Nuestro Sueno: Cultural Adaptation of a Couples Intervention to Improve PAP Adherence and Sleep Health Among Latino Couples With Implications for Alzheimer's Disease Risk
The goal of this clinical trial is to learn if the culturally adapted couples sleep health intervention (Nuestro Sueno) improves positive airway pressure use and sleep among Hispanic couples in which one partner was diagnosed…
- Trial name
- NCT06649929
- Testing
- Couples-based treatment- Patient, Couples-based treatment- Partner, Information control- Patient
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Brain Stimulation, Alzheimer Disease
Transcranial Alternating Current Stimulation (TACS) for Sleep Disturbances in Neurocognitive Disorders Due to Alzheimer's Disease
Background: Sleep disturbances are highly prevalent in ageing population and patients with age-related neurodegenerative diseases, which severely affect cognition and even lead to accumulated amyloid-β (Aβ).
- Conditions
- Brain Stimulation, Alzheimer Disease, tACS, Sleep Disturbance
- Trial name
- NCT05544201
- Testing
- High-definition transcranial current stimulation
- Where
- Hong Kong
- Volunteers
- 99 people
- Sponsor
- Chinese University of Hong Kong
Post-Traumatic Stress Disorders, Stress Disorders
Psychotherapy Treatment of Deployment-Related PTSD in Primary Care Settings
The purpose of this study is to evaluate Cognitive-behavioral therapy (CBT) for deployment-related post-traumatic stress disorder (PTSD) that can be used by behavioral health consultants working with Service Members in the…
- Conditions
- Post-Traumatic Stress Disorders, Stress Disorders, Combat Disorders
- Trial name
- NCT00974402
- Testing
- Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 35 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
GI Cancers, Gastrointestinal Cancer
Sleep Disturbances in Surgical Patients With GI Cancers: A Quantitative and Qualitative Analysis
The primary objective of the study is to determine sleep disturbance and its types among patients with gastrointestinal cancers during the perioperative period (preoperative and in-hospital stay following surgery) by using…
- Trial name
- NCT05044312
- Testing
- Sleeping Disturbances
- Sponsor
- M.D. Anderson Cancer Center
Bipolar Disorder, Insomnia
Mindfulness Therapy on Disrupted Sleep in Bipolar Disorder
The investigators propose to investigate the efficacy of a brief (4-session) Body Scan (BS) meditation intervention for individuals with bipolar I disorder with insomnia (i.e. difficulties falling or staying asleep).
- Conditions
- Bipolar Disorder, Insomnia, Hypersomnia, Sleep Problems
- Trial name
- NCT01764035
- Testing
- Body Scan (BS) Meditation Intervention, Brief Supportive Psychotherapy (SP)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Massachusetts General Hospital