Clinical trials: Disturbed Sleep
Post-Traumatic Stress Disorder, Sleep Disturbance
Aerobic Exercise Intervention for PTSD Symptoms and Sleep Quality After Earthquake
This randomized controlled trial aims to examine the effects of a moderate-intensity aerobic exercise program on post-traumatic stress disorder (PTSD) symptoms and sleep quality among earthquake survivors living in temporary…
- Trial name
- EX-PTSD (NCT07474259)
- Testing
- Moderate-Intensity Aerobic Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Malatya Turgut Ozal University
Cluster Headache
Sodium Oxybate in Patients With Episodic and Chronic Cluster Headache
The purpose of this study is to test the effects of sodium oxybate on headache response (frequency), sleep quality and quality of life in the prophylactic treatment of patients with chronic and episodic cluster headache.
- Trial name
- SOinCH (NCT02637648)
- Testing
- Sodium Oxybate
- Volunteers
- 60 people
- Sponsor
- Ramin Khatami
Restless Legs Syndrome (RLS), Restless Legs Syndrome
12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome
The purpose of this study is to assess the efficacy and safety of ropinirole CR-RLS in the treatment of patients with Restless Legs Syndrome and associated sleep disturbance and period limb movements during sleep.
- Trial name
- (CR-RLS) (NCT00373542)
- Testing
- ropinirole CR-RLS
- Where
- 45 sites in United States
- Volunteers
- 39 people
- Sponsor
- GlaxoSmithKline
Alcohol Abuse With Alcohol-Induced Sleep Disorder, Alcohol Use Disorder (AUD)
Smartphone-Based Intervention for Sleep Disturbance in Individuals Recovering From Alcohol Use Disorder
In order to assess the efficacy of the rhythm stabilization component of Health Rhythms' product in addressing sleep problems, investigators will recruit 128 outpatients over the age of 18, who are in early recovery (at least 2…
- Conditions
- Alcohol Abuse With Alcohol-Induced Sleep Disorder, Alcohol Use Disorder (AUD), Sleep Disorder, Sleep Disturbance
- Trial name
- NCT06108115
- Testing
- CueToSleep (Full Intervention Package)
- Where
- United States
- Volunteers
- 141 people
- Sponsor
- HealthRhythms, Inc.
Fatigue
The Effect of Reflexology on Radiation-related Fatigue in Breast Cancer Patients
Oncologic patients often report increased fatigue during and after radiation therapy. Reflexology treatment has been demonstrated to alleviate symptoms of fatigue, nausea, and anxiety in oncologic patients treated with…
- Trial name
- NCT00825682
- Testing
- Reflexology treatment.
- Where
- Israel
- Volunteers
- 72 people
- Sponsor
- Sheba Medical Center
Depression, Sleep Disturbance
Smart Light Therapy Glasses for Sleep and Mental Wellness
A pair of smart light therapy glasses (Lumos Glasses) was engineered to control the amount of blue light exposure at a person's eyes through a battery powered light source and nano-coating that reflect blue light.
- Trial name
- NCT07168954
- Testing
- Lumos Glasses
- Where
- Canada
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Waterloo
Perennial Allergic Rhinitis
Study of Nasonex® in Improving Sleep Disturbances Related to Perennial Allergic Rhinitis (Study P04909)(TERMINATED)
This study will hope to show that the treatment of the patient's perennial allergic rhinitis (PAR) using Nasonex® (mometasone furoate nasal spray) will result in improvement of the nasal symptoms of PAR and of nighttime…
- Trial name
- NCT00491374
- Testing
- Mometasone Furoate Nasal Spray
- Sponsor
- Schering-Plough
Sleep Disturbances
Individually Tailored Lighting System to Improve Sleep in Older Adults
In conjunction with investigators at the Cecil G. Sheps Center for Health Services Research, University of North Carolina (UNC) at Chapel Hill, we propose to develop and evaluate a low-cost, minimally obtrusive device that…
- Trial name
- NCT01855126
- Testing
- Blue light, Red light
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Rensselaer Polytechnic Institute
Sleep Apnea, Obstructive, Sleep Disorder
HSAT for OSA Management in Children
This clinical trial will compare the diagnostic accuracy of type II HSAT with PSG for determining OSA status following treatment with adenotonsillectomy in children
- Conditions
- Sleep Apnea, Obstructive, Sleep Disorder, Sleep Apnea Syndromes, Sleep Disturbance
- Trial name
- HOM-Kids (NCT05516524)
- Testing
- Home sleep apnea test, PSG
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Children's Hospital of Philadelphia
Pain, Nausea
Cannabis For Cancer-Related Symptoms
Clinical evidence is urgently needed to be able to advise patients on which cannabis-based products to take, or to avoid, in managing cancer-related symptoms.
- Conditions
- Pain, Nausea, Anxiety, Sleep Disturbance
- Trial name
- CAFCARS (NCT03948074)
- Testing
- Cannabis
- Where
- 8 sites in Canada
- Volunteers
- 91 people
- Sponsor
- Pippa Hawley
Sleep Disturbance
Developing and Testing a Spanish-Language Intervention to Reduce Cancer-Related Sleep Disturbance
The purpose of this study is to learn about how to provide treatment to cancer survivors who have difficulty sleeping.
- Trial name
- NCT04101526
- Testing
- Spanish-language Cognitive-Behavioral Therapy for Insomnia (CBT-I) delivered via videoconference
- Where
- 2 sites in United States, Puerto Rico
- Volunteers
- 30 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
AMCI - Amnestic Mild Cognitive Impairment, Sleep Disturbance
Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone
To investigate the effect of trazodone on sleep, hippocampal-dependent memory and hippocampal excitability. The investigators hypothesize that trazodone will improve total sleep time and proportion of time in Slow Wave Sleep…
- Trial name
- REST (NCT05282550)
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
type1diabetes, Sleep Disturbance
The Importance of Sleep for Diabetes Associated Tasks and Outcomes
Adolescents with type 1 diabetes (T1D) experience more disturbed sleep compared to their healthy peers, especially because they tend to spend less time in deep sleep, the most restoring part of sleep, potentially impacting…
- Trial name
- Sleep1child (NCT05762783)
- Where
- Denmark
- Volunteers
- 77 people
- Sponsor
- Steno Diabetes Center Copenhagen
Noise Exposure, Sleep Disturbance
Low Particle Emission and Low Noise Tyres
This study will investigate the biological mechanisms linking sleep disruption by noise and the development of disease. In a laboratory sleep study, the investigators will play synthesised automotive tyre sounds, investigating…
- Conditions
- Noise Exposure, Sleep Disturbance, Sleep Hygiene, Metabolic Disturbance
- Trial name
- LEON-T (NCT05611619)
- Testing
- Tyre noise - continuous flow, Tyre noise - discrete events, High noise level
- Where
- Sweden
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Sleep Disturbance
Esketamine vs Remimazolam for Postoperative Sleep Disturbance and Anxiety
To explore and compare the effects of esketamine and remimazolam on postoperative sleep disturbance in patients undergoing oocyte retrieval
- Trial name
- NCT06284668
- Testing
- normal Saline, Esketamine, Remimazolam
- Where
- China
- Volunteers
- 315 people
- Sponsor
- Tianjin Medical University General Hospital
Insomnia, Depression
Music to Improve Sleep Quality in Adults With Depression and Insomnia
Insomnia is a common sleep disorder for patients with depression. This has a major impact on the quality of life for the individual. The aim is to investigate, whether music intervention is effective in 1.
- Trial name
- MUSTAFI (NCT03676491)
- Testing
- Music Intervention
- Where
- Denmark
- Volunteers
- 112 people
- Sponsor
- Aalborg University Hospital
Lung Cancer, Sleep Disturbance
The Associations of Sleep Disturbance With Therapy Efficacy and Prognosis of Lung Cancer
This is the prospective, observational cohort study (Nezha) to explore the associations of sleep disturbance with progression, efficacy of immune checkpoint inhibitors (ICIs) and prognosis of Lung Cancer.
- Conditions
- Lung Cancer, Sleep Disturbance, Immune Checkpoint Inhibitors, Cancer, Treatment-Related
- Trial name
- Nezha (NCT06975384)
- Testing
- Exposure: sleep disturbance status
- Where
- China
- Volunteers
- 1,270 people
- Sponsor
- Second Xiangya Hospital of Central South University
Major Abdominal Surgery, Postoperative Delirium (POD)
MInimizing Delirium With Nasal Dexmedetomidine-InducEd Sleep (MIDDIES)
This study aims to determine whether, compared with placebo, the nighttime self-administration of a nasal dexmedetomidine is effective at inducing sleep and preventing postoperative delirium in high-risk patients.
- Conditions
- Major Abdominal Surgery, Postoperative Delirium (POD), Sleep Disturbances, Intranasal Dexmedetomidine
- Trial name
- MIDDIES (NCT07538284)
- Testing
- Dexmedetomidine
- Volunteers
- 400 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Relapsing Remitting Multiple Sclerosis, Sleep Initiation and Maintenance Disorders
Eszopiclone for Improving Sleep in Multiple Sclerosis (MS)
The purpose of this study is to determine if people with multiple sclerosis (MS) and fatigue have disrupted sleep, as was suggested in previous studies, and whether treating the disruptions of sleep improves the fatigue.
- Conditions
- Relapsing Remitting Multiple Sclerosis, Sleep Initiation and Maintenance Disorders, Fatigue
- Trial name
- NCT00594087
- Testing
- eszopiclone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Vermont
Sickle Cell Disease, Sleep Disturbance
Sleep and Pain in Sickle Cell Disease
This is a study testing the effects of behavioral sleep interventions on pain and brain function in sickle cell disease.
- Conditions
- Sickle Cell Disease, Sleep Disturbance, Pain
- Trial name
- NCT03150433
- Testing
- Behavioral symptom management, Sickle cell disease management
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Johns Hopkins University